Abstract
We performed classical molecular dynamics simulations using both fixed-charge and polarizable water and protein force fields to contrast the hydration dynamics near hydrophilic and amphiphilic peptides as a function of temperature. The high peptide concentrations we use serve as a model for the surf...
|
PMID: 19425247
PDF is available here.
Abstract
The extension of the concepts of Fractal Geometry (Mandelbrot [1983]) toward the life sciences has led to significant progress in understanding complex functional properties and architectural / morphological / structural features characterising cells and tissues during ontogenesis and both normal an...
|
PMID: 19718622
PDF is available here.
Abstract
The domesticated cow is the latest farm animal to have its genome sequenced and deciphered. The members of the Bovine Genome Consortium have published a series of papers on the assembly and what the sequence reveals so far about the biology of this ruminant and the consequences of its domestication....
|
PMID: 19439025
PDF is available here.
Abstract
We present the details of the existing kinetic simulation methods and discuss their strengths and shortcomings. A list of the publicly available kinetic simulation tools and our reflections for future prospects are also provided....
|
PMID: 19381542
PDF is available here.
Abstract
We identify and establish important issues that affect the acquisition and analysis of biological samples with PEEM. We will briefly review the biological impact and importance of PEEM with respect to our work. The article also concludes with a discussion of some of the current challenges that must...
|
PMID: 19076307
PDF is available here.
Abstract
The synthesis of indolin-2-one derivatives substituted in the 3-position by an aminomethylene group bearing either an ornithine or a lysine residue is described. The inhibitory activities of these compounds toward a panel of eight kinases were examined. Furthermore, the antibacterial activities of t...
|
PMID: 18313174
PDF is available here.
Abstract
Concurrent administration of radiation and chemotherapy has emerged as a dominant form of cancer treatment. Nevertheless, our understanding of the specific mechanisms of interaction between radiation and chemotherapy is still evolving. Biological evidence gained in experimental cell lines and tumors...
|
PMID: 16378901
PDF is available here.
Abstract
We study light propagation in biological tissue containing an absorbing obstacle. In particular, we solve the infinite-domain problem in which an absorbing plate of negligible thickness prevents a portion of the light from the source from reaching the detector plane. Inasmuch as scattering in the me...
|
PMID: 14765913
PDF is available here.
Abstract
We present reconstruction techniques for recovering phosphorescent objects in highly scattering media based on the telegraph equation and two regularization methods, i.e., the Tikhonov-Phillips regularization and the maximum entropy method. Theoretical results are experimentally validated, and the r...
|
PMID: 14765914
PDF is available here.
Abstract
A nonlinear, Bayesian optimization scheme is presented for reconstructing fluorescent yield and lifetime, the absorption coefficient, and the diffusion coefficient in turbid media, such as biological tissue. The method utilizes measurements at both the excitation and the emission wavelengths to reco...
|
PMID: 12790460
PDF is available here.
Abstract
We report what to our knowledge is a novel perturbation approach for time-resolved transmittance imaging in diffusive media, based on the diffusion approximation with extrapolated boundary conditions. The model relies on the method of Padé approximants and consists of a nonlinear approximation of t...
|
PMID: 12790465
PDF is available here.
Abstract
Schizophrenia is a common and debilitating illness, characterized by chronic psychotic symptoms and psychosocial impairment that exact considerable human and economic costs. The literature in electronic databases as well as citations and major articles are reviewed with respect to the phenomenology,...
|
PMID: 12788337
PDF is available here.
Abstract
The role of fruit and vegetables in human nutrition and public health are taken into account in most nutritional recommendations. Fruit and vegetables contain an abundance of phenolic substances, terpenoids and other natural antioxidants that have been associated with protection from and treatment o...
|
PMID: 12743459
PDF is available here.
Abstract
We demonstrate the accuracy of these two approximations by solving the problem of reflection and transmission of a plane wave normally incident on a slab composed of a uniform scattering medium....
|
PMID: 12542322
PDF is available here.
Abstract
We describe a case of cervicofacial purpura in a powerlifter attributed to the accompanying Valsalva-associated increased arterial pressure. Powerlifting should be added to the list of activities that may cause purpura....
|
PMID: 12234164
PDF is available here.
Abstract
Examples of elation, grandiosity, decreased need for sleep, racing thoughts, and hypersexuality in PEA-BP subjects were compared to examples in prepubertal normal controls and to examples in late teenage/adult-onset mania. Because it is not intuitive that children can be pathologically happy or expa...
|
PMID: 12014593
PDF is available here.
Abstract
Early-onset poststroke major depression was associated with a higher frequency of vegetative symptoms and larger lesion volume than late-onset major depression. Similarly, early-onset minor depression was associated with poorer social functioning and a higher frequency of melancholic, vegetative, an...
|
PMID: 12213692
PDF is available here.
Abstract
In an article in the August 2000 issue of Demography titled "Racial Differences in Birth Health Risk: A Quantitative Genetic Approach," van den Oord and Rowe attempted to study the genetic and environmental factors contributing to the black/white gap in infant birth weight. Their findings indicate t...
|
PMID: 11723952
PDF is available here.
Abstract
An analytical solution is developed to quantify a site-specific fluorophore lifetime perturbation that occurs, for example, when the local metabolic status is different from that of surrounding tissue. This solution may be used when fluorophores are distributed throughout a highly turbid media and t...
|
PMID: 11444544
PDF is available here.
Abstract
Human organism is interpenetrated by the world of microorganisms, from the conception until the death. This interpenetration involves different levels of interactions between the partners including trophic exchanges, bi-directional cell signaling and gene activation, besides genetic and epigenetic p...
|
PMID: 11313655
PDF is available here.
Abstract
We used 420 M. tuberculata, from Sumidouro. Fourteen different latex concentrations were tested using World Health Organization general methodology. Probit analysis was used for LD90 and LD50 determination. The LD50 was 3.57 mg/l and LD90 was 6.22 mg/l. At the highest concentration (10 mg/l) there w...
|
PMID: 11285483
PDF is available here.
Abstract
The antifouling activities of vacuum-dried 70% aqueous alcohol extracts of four gorgonian and five soft corals against four dominant marine fouling diatoms (Navicula subinflata Grun, N. crucicula Smith, Amphora sp., Nitzschia sp.) are described. Of the 36 possible combinations (9 corals x 4 diatoms)...
|
PMID: 11327107
PDF is available here.
Abstract
The phenomenon of self-healing forces has again and again challenged doctors in the different historical periods of medical science. They relied on effects of self-healing forces in diagnosis and therapy. They also tried to explain these effects based on the current model of organism. The understand...
|
PMID: 11939425
PDF is available here.
Abstract
These results suggest the existence of compounds, other than cuticular lipids, responsible for the absence of aggressiveness in the ants. The case of V. tertianus is relatively new as myrmecophily within Hesperiidae has been described only once. Moreover, it preferentially involves a member of the P...
|
PMID: 11019365
PDF is available here.
Abstract
I and Tunnelling bacterial attack, termites are the main wood biodegradation agents....
|
PMID: 10974706
PDF is available here.
Abstract
Life cannot be simply defined in biochemical terms but it is associated with autodynamic behaviour. This fact implies that all aspects of cell biology should be viewed in terms of the resultant temporal features. Theoretical arguments indicate that the dynamic state can be explained only by the exis...
|
PMID: 10924230
PDF is available here.
Abstract
The living world is an exciting and inexhaustible source of high performance solutions to the multitude of biological problems, which were attained as a result of a natural selection, during the millions and millions years evolution of life on Earth. This work presents and comments some examples of...
|
PMID: 10423826
PDF is available here.