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Biological Factors (10)
Articles on Biological Factors
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Two-dimensional LC-MS fractioning and cross-matching of mass spectrometric data for rational identification of bioactive compounds in crude ...
J Sep Sci 34(23):3359-63 (2011) PMID 22086770
We report on a novel two stage rational LC-MS strategy of extracts already pre-screened and proven to contain bioactive compound(s). All extracts are initially fractionated using one and the same LC condition with parallel mass spectrometric detection. Fractions containing bioactive compound(s) are... -
Ulcerative colitis.
N Engl J Med 365(18):1713-25 (2011) PMID 22047562
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Huaier aqueous extract inhibits proliferation of breast cancer cells by inducing apoptosis.
Cancer Sci 101(11):2375-83 (2010) PMID 20718753
We aim to investigate its inhibitory effect on both MCF-7 and MDA-MB-231 cells, and explore the possible mechanisms of its anticancer effect. Cell viability and motility were measured by MTT and invasive assays, migration and scratch assays in vitro, respectively. The distribution of cell cycle, PI-... -
Procyanidin-rich fractions from Parkia biglobosa (Mimosaceae) leaves cause redox-sensitive endothelium-dependent relaxation involving NO and...
J Ethnopharmacol 132(1):246-50 (2010) PMID 20727401
Parkia biglobosa leaves are traditionally used as an antihypertensive agent in Benin. The present study assessed the vasorelaxant activity of different Parkia biglobosa leaf extracts using isolated porcine coronary artery rings. A hydroalcoholic leaf extract was submi... -
International workshop on "Modeling interaction in biomolecules IV", held in Hrubá Skála, 14-19 September 2009.
(2010) PMID 20848149
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An extract of the pleurotus ostreatus mushroom bolsters the glutathione redox system in various organs of aged rats.
J Med Food 13(4):771-8 (2010) PMID 20673055
This study is to investigate the putative effect of an extract of the oyster mushroom, Pleurotus ostreatus, on reduced glutathione (GSH) and its metabolic enzymes in major organs of male albino rats. A significant (P < .05) decrease in the level of GSH was observed in liver, kidneys, heart, and brai... -
[Determination of biological activity of extract from hirudo by N-benzoyl-L-arginine ethyl ester].
Zhongguo Zhong Yao Za Zhi 35(15):1990-2 (2010) PMID 20931853
As a potent anticoagulant, leech a traditional Chinese medicine, has become increasing topics. Hirudin, which is the primary effective component in leech, is a specific and efficient inhibitor of thrombin, mainly used in prevention and treatment of thrombus on the clinic practice. However, there is... -
[Biologic agents in myositis: unsolved questions].
Med Clin (Barc) 135(6):263-4 (2010) PMID 20451933
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Solid-phase microextraction in bioanalysis: New devices and directions
J Chromatogr 1217(25):20 (2010) PMID 20031143
The primary objective of this review is to discuss recent technological developments in the field of solid-phase microextraction that have enhanced the utility of this sample preparation technique in the field of bioanalysis. These developments include introduction of various new biocompatible coati... -
[OSMAC (one strain many compounds) approach in the research of microbial metabolites--a review].
Wei Sheng Wu Xue Bao 50(6):701-9 (2010) PMID 20687332
Microbial secondary metabolites have a wide range of biological activities due to their structural diversity and have been proved a major source for drug lead compounds. However,the traditional method of a single culture restricts the metabolic pathways of microorganisms and as a result many metabol...
