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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Biocompatible Materials (3):
Recent article
Biocompatible Materials
Biomaterials (32)34 2011
Abstract
We have developed a bioreactor containing single hollow fiber membranes that requires relatively small amounts of cells. Special hollow fiber membranes with the skin layer on the outer surface and consisting of polyethersulfone/polyvinylpyrrolidone were developed. The results suggested that such hol...
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PMID: 21872923
PDF is available here.
PDF is available here.
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Biomaterials (32)34 2011
Abstract
We have developed a bioreactor containing single hollow fiber membranes that requires relatively small amounts of cells. Special hollow fiber membranes with the skin layer on the outer surface and consisting of polyethersulfone/polyvinylpyrrolidone were developed. The results suggested that such hol...
|
PMID: 21872923
PDF is available here.
PDF is available here.
Biomaterials (32)34 2011
Abstract
We have developed a bioreactor containing single hollow fiber membranes that requires relatively small amounts of cells. Special hollow fiber membranes with the skin layer on the outer surface and consisting of polyethersulfone/polyvinylpyrrolidone were developed. The results suggested that such hol...
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PMID: 21872923
PDF is available here.
PDF is available here.
Abstract
We have developed methods to coculture osteoblasts, which are the primary cell type making up bone, and endothelial cells, which form the vasculature supplying cells in the bone with oxygen and nutrients to survive on 2- and 3-D biomaterials....
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PMID: 21042976
PDF is available here.
PDF is available here.
Abstract
Injectable hydrogels are being developed as potential translatable materials to influence the cascade of events that occur after myocardial infarction. These hydrogels, consisting of both synthetic and natural materials, form through numerous chemical crosslinking and assembly mechan...
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PMID: 21710332
PDF is available here.
PDF is available here.
Abstract
This article reviews current applications and novel candidate biomaterials for use as tissue-engineered scaffolds in pediatric cardiac tissue engineering. This overview of different types of biomaterials includes naturally derived and synthetic polymers and their biological, physical...
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PMID: 21647794
PDF is available here.
PDF is available here.
Acta Biomaterialia (7)10 2011
Abstract
Although Bioglass® has existed for nearly half a century its ability to trigger bone formation and tuneable degradability is vastly superior to other bioceramics, such as SiO(2)-CaO bioactive glasses. The sol-gel process of producing glass foams is well established for SiO(2)-CaO co...
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PMID: 21689791
PDF is available here.
PDF is available here.
Abstract
Recent pre-clinical and clinical studies indicate that certain exogenous stem cells and biomaterials can preserve cardiac tissue after myocardial infarction. Regarding stem cells, a growing body of data suggests that the short-term positive outcomes are mainly attributed to paracrine...
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PMID: 21735303
PDF is available here.
PDF is available here.
Abstract
We provide a brief overview of valves in clinical use as well as of the materials being investigated as novel tissue-engineered heart valve scaffolds. Additionally, we focus on natural-based biomaterials for promoting cell behavior that is indicative of the developmental biology process that occurs...
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PMID: 21751069
PDF is available here.
PDF is available here.
Biomedical Materials (6)5 2011
Abstract
Our studies strengthen the application of electrospun PLGA/Gel nanofibers as a bio-mechanical support for injured myocardium and as a potential substrate for induction of endogenous cardiomyocyte proliferation, ultimately reducing the cardiac dysfunction and improving cardiac remodeling....
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PMID: 21813957
PDF is available here.
PDF is available here.
Abstract
Abstract
Biomedical Materials (6)5 2011
Abstract
We aim to design new biocompatible materials to overcome this. In this paper we investigate the use of photoelastomers for artificial vascular constructs since they may be precisely structured by means of additive manufacturing technologies. Hence, 3D computer aided design and manufacturing technolo...
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PMID: 21849722
PDF is available here.
PDF is available here.
Abstract
Abstract
Tissue engineering promises to restore tissue and organ function following injury or failure by creating functional and transplantable artificial tissues. The development of artificial tissues with dimensions that exceed the diffusion limit (1-2 mm) will require nutrients and oxygen...
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PMID: 21892744
PDF is available here.
PDF is available here.
Acta Biomaterialia (7)10 2011
Abstract
In this study, a two-part bone tissue engineering scaffold was investigated. The scaffold consists of a solid poly(propylene fumarate) (PPF) intramedullary rod for mechanical support surrounded by a porous PPF sleeve for osseointegration and delivery of poly(dl-lactic-co-glycolic aci...
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PMID: 21757034
PDF is available here.
PDF is available here.
Acta Biomaterialia (7)10 2011
Abstract
These results correlate with measurements of the mechanical properties of the scaffolds, since both the ultimate tensile strength and tensile modulus of the cell seeded scaffolds had increased by the end of the culture period. This experiment demonstrates that porcine and avian collagen could be use...
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PMID: 21723967
PDF is available here.
PDF is available here.
Abstract
Abstract
Biomacromolecules (12)9 2011
Abstract
We used noncrystalline poly(trimethylene carbonate) (PTMC) or poly(δ-valerolactone-co-ε-caprolactone) (PVLCL) macrodiols of different molecular weights as SSs that were reacted with 1,4-diisocyanatobutane and chain extended with 1,4-diaminobutane. Mechanical properties of the PUUs were characteriz...
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PMID: 21755999
PDF is available here.
PDF is available here.
Biomacromolecules (12)9 2011
Abstract
The final goal of the present study was the development of a 3-D chitosan dressing that would shorten the healing time of skin wounds by stimulating migration, invasion, and proliferation of the relevant cutaneous resident cells. Three-dimensional chitosan nanofibrillar scaffolds pro...
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PMID: 21761871
PDF is available here.
PDF is available here.
Biomacromolecules (12)9 2011
Abstract
I and elastin was significantly up-regulated when compared with TCPS control, whereas collagen III was down-regulated on PHBV fibers and 2-D film after 14 days in culture. The less ductile PHBV 2-D films showed higher levels of elastin expression. Furthermore, the PHBV fibers in the presence and abs...
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PMID: 21800891
PDF is available here.
PDF is available here.
Biomacromolecules (12)9 2011
Abstract
Polyhydroxyalkanoates (PHA) synthesis genes phbC and orfZ cloned from Ralstonia eutropha H16 were transformed into beta-oxidation weakened Pseudomonas putida KTOY08ΔGC, a mutant of P. putida KT2442. The recombinant P. putida strain termed KTHH06 was able to produce a short-chain-len...
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PMID: 21863836
PDF is available here.
PDF is available here.
Abstract
Abstract
We will be focusing on ESCs as a promising cell source for cartilage regeneration, the various strategies and approaches employed in chondrogenic differentiation and tissue engineering, the associated outcomes from animal studies, and the challenges that need to be overcome before clinical applicati...
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PMID: 21188652
PDF is available here.
PDF is available here.
Abstract
Natural biopolymers, such as collagen or chitosan, are considered ideal for biomedical scaffolds. However, low processability of the materials has hindered the fabrication of designed pore structures controlled by various solid freeform-fabrication methods. A new technique to fabrica...
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PMID: 21472408
PDF is available here.
PDF is available here.
Abstract
Mandibular defect occurs more frequently in recent years, and clinical repair operations via bone transplantation are difficult to be further improved due to some intrinsic flaws. Tissue engineering, which is a hot research field of biomedical engineering, provides a new direction fo...
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PMID: 21887853
PDF is available here.
PDF is available here.
Abstract
Recently, poly(ester urethanes) were investigated for use as ligament grafts due to their exceptional mechanical properties and highly tunable structure; however, these grafts are susceptible to hydrolytic degradation that occurs independent of tissue regeneration. To address this li...
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PMID: 21681959
PDF is available here.
PDF is available here.
Acta Biomaterialia (7)8 2011
Abstract
The objective of the present in vitro research was to investigate cardiac tissue cell functions (specifically cardiomyocytes and neurons) on poly(lactic-co-glycolic acid) (PLGA) (50:50 wt.%)-carbon nanofiber (CNF) composites to ascertain their potential for myocardial tissue engineer...
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PMID: 21571106
PDF is available here.
PDF is available here.
Abstract
Fibrin glue (FG) is used in a variety of clinical applications and in the laboratory for localized and sustained release of factors potentially important for tissue engineering. However, the effect of different fibrinogen concentrations on FG scaffold delivery of bioactive adeno-asso...
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PMID: 21449684
PDF is available here.
PDF is available here.
Acta Biomaterialia (7)8 2011
Abstract
A low density and high strength alloy, Ca65Mg15Zn20 bulk metallic glass (CaMgZn BMG), was evaluated by both in vitro tests on ion release and cytotoxicity and in vivo implantation, aimed at exploring the feasibility of this new biodegradable metallic material for potential skeletal a...
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PMID: 21571105
PDF is available here.
PDF is available here.
The use of veritas collagen matrix to reconstruct the posterior chest wall after costovertebrectomy.
Abstract
We describe the reconstruction of the chest wall with Veritas (Synovis, St Paul, MN) collagen matrix of a posterior chest wall defect after costovertebrectomy for Ewing's sarcoma. En bloc resection was performed, including partial D7 through D9 vertebrectomy along with the posterolateral segments of...
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PMID: 21718821
PDF is available here.
PDF is available here.
Acta Biomaterialia (7)7 2011
Abstract
Ultrathin films (also called nanofilms) are two-dimensional (2-D) polymeric structures with potential application in biology, biotechnology, cosmetics and tissue engineering. Since they can be handled in liquid form with micropipettes or tweezers they have been proposed as flexible s...
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PMID: 21421086
PDF is available here.
PDF is available here.
Biomacromolecules (12)6 2011
Abstract
It was more than 50 years ago that an appearance of birefringence in alginate gels prepared under cation flow was reported for the first time, however, the anisotropic structure of the alginate gel has not been studied in detail. In the present study, anisotropic Ca-alginate gels wer...
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PMID: 21504159
PDF is available here.
PDF is available here.
Biomacromolecules (12)6 2011
Abstract
Currently, biomedical engineering is rapidly expanding, especially in the areas of drug delivery, gene transfer, tissue engineering, and regenerative medicine. A prerequisite for further development is the design and synthesis of novel multifunctional biomaterials that are biocompati...
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PMID: 21469742
PDF is available here.
PDF is available here.
Biomacromolecules (12)6 2011
Abstract
We report an approach for the fabrication of fully biodegradable self-rolled tubes based on patterned polysuccinimide/polycaprolactone bilayers. These polymers are biocompatible, biodegradable, produced industrially, and are already approved for biomedical purposes. Both polycaprolactone and polysuc...
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PMID: 21524116
PDF is available here.
PDF is available here.
Biomacromolecules (12)6 2011
Abstract
We have designed and produced a modular, recombinant resilin-like polypeptide bearing both mechanically active and biologically active domains to create novel biomaterial microenvironments for engineering mechanically active tissues such as blood vessels, cardiovascular tissues, and vocal folds. Pre...
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PMID: 21553895
PDF is available here.
PDF is available here.
Biomacromolecules (12)6 2011
Abstract
This Review is focused on the growing interest brought to phosphorus-containing organic materials for applications in the biomedical field, mainly because of their properties such as biocompatibility, hemocompatibility, and protein adsorption resistance. It mainly describes relevant...
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PMID: 21553908
PDF is available here.
PDF is available here.
Abstract
Hydrogels are three-dimensional networks of crosslinked hydrophilic polymers widely used for protein delivery and tissue engineering. To be eligible for in vivo applications, the hydrogels should not evoke an adverse tissue response. In this study the angiogenic and inflammatory resp...
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PMID: 21442723
PDF is available here.
PDF is available here.
Biomedical Materials (6)3 2011
Abstract
A key step during the synthesis of collagen constructs is the incubation of monomeric collagen in phosphate buffer saline (PBS) to promote fibrillogenesis in the collagen network. Optimal PBS-treatment conditions for monomeric collagen solutions to induce gelation are well establishe...
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PMID: 21540522
PDF is available here.
PDF is available here.
Vojnosanitetski pregled (68)5 2011
Abstract
Abstract
Tissue engineering approaches have been successfully used in repairing bone defects and have become a viable alternative to autologous bone. The aim of the present study was to investigate if a construct of porous beta-tricalcium phosphate (β-TCP) combined with osteogenically induce...
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PMID: 21226625
PDF is available here.
PDF is available here.
Abstract
A new class of biomimetic, bioresorbable apatitic calcium phosphate cement (CPC) was recently developed. The handling characteristics, and the ability to harden at body temperature in the presence of physiological saline, make this material an attractive clinical bone substitute and...
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PMID: 21384543
PDF is available here.
PDF is available here.
Medicinal Chemistry (7)3 2011
Abstract
We report that by using a simple chemical modification technique we can obtain new biomaterials, specifically suitable for biomedical applications. Concretely, we describe the chemical modification of gelatin and the suitable characteristics of the modified protein to develop new nanomedicines. This...
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PMID: 21486207
PDF is available here.
PDF is available here.
Abstract
We have developed a simple and controllable approach that allows construction of a two-level, three-dimensional (3D) networked structure to provide sufficient calcium source and achieve desired mechanical function and mass transport (permeability and diffusion) properties. Using a nontoxic cross-lin...
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PMID: 21491931
PDF is available here.
PDF is available here.
Abstract
Synthetic biomaterials serve as a cornerstone in the development of clinically focused regenerative medicine therapies that aim to reduce suffering and prolong life. Recent improvements in biodegradable elastomeric materials utilize natural extracellular matrix proteins as inspiratio...
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PMID: 21229578
PDF is available here.
PDF is available here.
Minerva chirurgica (66)2 2011
Abstract
Abdominal wall defects and tissue loss that result from traumatic injury, surgical resection, failure of abdominal closures (i.e., incisional hernias) or ventral hernias are a common clinical problem. Currently, the repair of these tissue defects represents a reconstructive challenge to surgeons. The...
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PMID: 21593715
PDF is available here.
PDF is available here.
Abstract
We developed microfibrous scaffolds made from blends of PGS and poly(ε-caprolactone) (PCL) using a standard electrospinning set-up. At a given PGS:PCL ratio, higher voltage resulted in significantly smaller fibre diameters (reduced from ∼4 µm to 2.8 µm; p < 0.05). Further increase in voltage re...
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PMID: 20669260
PDF is available here.
PDF is available here.
Abstract
Our previous study has shown significant improvement in tensile properties of these materials due to the enhanced interfacial adhesion between the polymer matrix and HA particles. To further investigate the potential applications of these composites in bone repair and other orthopedic surgeries, a s...
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PMID: 21416229
PDF is available here.
PDF is available here.
Abstract
We searched for cellular pathways that impair the heat shock response in mesothelial cells after PDF-exposure. In a dose-response experiment, increasing PDF-exposure times resulted in rapidly increasing mesothelial cell damage but decreasing HSP expression, confirming impaired heat shock response. U...
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PMID: 21435443
PDF is available here.
PDF is available here.
Abstract
We have engineered highly compliant small-diameter arterial constructs by culturing primary adult baboon arterial SMCs under pulsatile perfusion on tubular, porous, elastomeric scaffolds composed of poly(glycerol sebacate) (PGS). This study investigates the effect of hydrostatic pressure on the biol...
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PMID: 21268239
PDF is available here.
PDF is available here.
Abstract
Poly(ethylene glycol) (PEG) hydrogels hold great promise as in vivo cell carriers for tissue engineering. To ensure appropriate performance of these materials when implanted, the host response must be well understood. The objectives for this study were to characterize the temporal ev...
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PMID: 21268236
PDF is available here.
PDF is available here.
Abstract
Chitosan/hydroxyapatite scaffolds could be used for bone regeneration in case the application of auto- or allografts is impossible. The objective of the present work was to characterize and study in vivo biodegradation of simple chitosan/hydroxyapatite scaffolds. For this purpose, a...
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PMID: 21268238
PDF is available here.
PDF is available here.
Abstract
Pore formation and pore closure in poly(D,L-lactide-co-glycolide)-based drug delivery systems are two important processes as they control the release of the encapsulated drug. The phenomenon pore closure was investigated by studying the effects of the pH and the temperature of the re...
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PMID: 21094192
PDF is available here.
PDF is available here.
Abstract
We focus on construction of cartilage, tendon and bone. The purpose of this review was to summarize the advances in the engineering of these three tissues, particularly focusing on tissue regeneration and defect repair in our laboratory. In cartilage engineering, articular cartilage was reconstructe...
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PMID: 21681676
PDF is available here.
PDF is available here.
Abstract
In this paper, the poly(vinyl alcohol)/poly(epsilon-caprolactone)-PEG-poly(epsilon-caprolactone)/nano-hydroxyapatite (PVA/PCEC/n-HA) composite membranes were prepared by solution casting and evaporation methods. The effect of n-HA content on the properties of the composite membranes...
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PMID: 21449393
PDF is available here.
PDF is available here.
Abstract
Porous scaffold biomaterials may offer a clinical alternative to bone grafts; however, scaffolds alone are typically insufficient to heal large bone defects. Numerous studies have demonstrated that osteoinductive growth factor significantly improves bone repair. In this study, a strategy combining de...
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PMID: 21473456
PDF is available here.
PDF is available here.
Abstract
Abstract
To study clinical and radiographic outcome of patients who underwent the Cervios cage-assisted anterior cervical discectomy and fusion (ACDF) without plate fixation in single to two-level degenerative disc disease (DDD).
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PMID: 21534365
PDF is available here.
PDF is available here.
Biomedical Materials (6)1 2011
Abstract
We report on the development of a CpG ODN-loaded suture that can close up the wound following tumor excision and provide sustained localized delivery of CpG ODN to treat local disease recurrence. The suture was prepared by melt extruding a mixture of polylactic acid-co-glycolic acid (PLGA 75:25 0.47...
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PMID: 21206000
PDF is available here.
PDF is available here.