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Sodium Fluoride (1):
Recent article
Sodium Fluoride
Abstract
We already reported that IPF% values were highly fluctuated in stored whole blood sample with EDTA-2K at 4 degrees C day by day. In this study we investigated the stability of IPF% in blood samples obtained from 11 patients with chronic immune thrombocytopenic purpura (ITP) and 19 healthy volunteers...
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PMID: 21706858
PDF is available here.
PDF is available here.
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Abstract
Excessive fluoride ingestion has been identified as a risk factor for fluorosis and oxidative stress. The oxidative stress results from the loss of equilibrium between oxidative and antioxidative mechanisms that can produce kinase activation, mitochondrial disturbance and DNA fragmentation, resultin...
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PMID: 20738751
PDF is available here.
PDF is available here.
Food and Chemical Toxicology (48)10 2010
Abstract
Ninety female Balb/c mice were used. The animals were allocated to evenly six groups. While the first group was maintained as control, Groups 3, 4, 5, and 6 were administered 750 ppm, 1500 ppm, 3000 ppm, and 6000 ppm of N-acetylcysteine, respectively, for a period of 15 days. After day 15, Groups 2-...
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PMID: 20637250
PDF is available here.
PDF is available here.
Journal of Dentistry (38)10 2010
Abstract
To investigate the effect of an aqueous sodium fluoride solution of increasing concentration on erosion and attrition of enamel and dentine in vitro.
Enamel and dentine sections from caries-free human third molars were polished flat and taped (exposing a 3 mm x 3 mm area) before being randomly alloc...
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PMID: 20600557
PDF is available here.
PDF is available here.
Abstract
Enamel surface microhardness significantly decreased after bleaching with nonenhanced 10% CP (WHI). The chemical analyses suggest F uptake promoted by high-concentrate F bleaching gels (CPF, OPA, and PN) and a F loss with nonenhanced 10% CP bleaching gels (PLA, WHI). CP agent enhanced with Ca (CPCa)...
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PMID: 20657849
PDF is available here.
PDF is available here.
Biology of the Cell (102)9 2010
Abstract
We show that Cdc42 (cell-division cycle 42), Rac1 and RhoA activities are stimulated in NaF-treated cells. However, podosome assembly is dependent on Cdc42 and Rac1, but not RhoA. Although the sole activation of Cdc42 is sufficient to induce individual podosomes, a balance between RhoGTPase activiti...
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PMID: 20504277
PDF is available here.
PDF is available here.
Abstract
Solutions containing tin and fluoride exhibit remarkable anti-erosive properties with tin ions as a major agent. To elucidate its mechanism of action in dentine, the tin uptake on and in the tissue was investigated and related to histological findings and substance loss. Samples were treated twice d...
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PMID: 20662911
PDF is available here.
PDF is available here.
Abstract
Rats receiving fluoride during the whole pregnancy up to the 9th day of lactation showed, when isolated at 10th day of life, a reduced rate of ultrasonic vocalizations (UV) in male pups (NaF 5.0 mg) and, in 90th days male rats, an increase of the Pre-Pulse Inhibition (PPI) with a reduction of the Pe...
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PMID: 20712257
PDF is available here.
PDF is available here.
Abstract
Chlorhexidine (CHX) is the most tested and leading oral antiseptic agent. Zinc as an active ingredient has shown additive and synergistic effect and when Sodium fluoride (NaF) was used it failed to show added effectiveness and the combined effect of NaF and Zinc chloride (ZnCl2) both as active ingre...
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PMID: 21188919
PDF is available here.
PDF is available here.
Abstract
There is low quality evidence suggesting that sodium fluoride may be of benefit to preserve hearing and reduce vestibular symptoms in patients with otosclerosis....
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PMID: 20163750
PDF is available here.
PDF is available here.
Abstract
33 subjects were enrolled and completed the study. The adjusted mean volatile sulfur compound (VSC) levels were significantly lower in the SnF2 groups than the NaF groups, at both 24 (P < 0.01) and 28 (P < 0.001) hours post baseline time points. Tongue brushing did not provide additional statistical...
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PMID: 20718217
PDF is available here.
PDF is available here.
Abstract
The ProSeal and Light Bond treatment groups exhibited significant reductions in mean lesion depths as compared to the controls (P < 0.05). ProSeal with NaF rinsing and Light Bond with NaF rinsing treatment groups exhibited significant reductions in mean lesion depth when compared to Pro Seal and Lig...
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PMID: 20718218
PDF is available here.
PDF is available here.
Abstract
Fluorosis or crippling disease is one of the existing environmental challenges for animal and human beings in most parts of the globe. In the present study, sodium fluoride alone and with aluminium sulphate (ameliorative agent) was administered orally daily for 30 days in healthy goats of group 1 an...
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PMID: 19652927
PDF is available here.
PDF is available here.
Archives of Toxicology (84)5 2010
Abstract
Sperm hyperactivation is crucial for a successful fertilization; however, the influence of fluoride (F) to hyperactivation is still in its infancy. The purpose of this study was to investigate the effect of sodium fluoride (NaF) on sperm hyperactivation, Ca2+/CALM-CAMK2 signaling, and CatSper1 and C...
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PMID: 20052459
PDF is available here.
PDF is available here.
Abstract
The present study was aimed to evaluate curcumin as a potential natural antioxidant to mitigate the genotoxic effects of arsenic (As) and fluoride (F) in human peripheral blood lymphocytes. The study was divided into nine groups consisting of negative control, positive control treated with ethyl met...
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PMID: 20170701
PDF is available here.
PDF is available here.
Abstract
The study aimed to compare the wear behaviour of human and bovine dentine due to toothbrushing with different relative dentin abrasivity (RDA) toothpastes. Forty human and 40 bovine dentine samples were prepared from bovine lower incisors or human premolars roots, and baseline surface profiles were...
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PMID: 19452177
PDF is available here.
PDF is available here.
Abstract
A total of 156 fractures were detected at baseline skeletal survey, and 200 fractures were detected at PET. Compared with the reference standard (findings in the 14 patients who underwent baseline and follow-up skeletal survey), PET had sensitivities of 85% for the detection of all fractures, 92% fo...
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PMID: 20308455
PDF is available here.
PDF is available here.
Abstract
This method is an efficient, space-saving and extremely low-cost operation that easily performed in an aseptic environment meeting GMP standard. The quality of the "Sodium fluoride ((18)F) injection" so yielded meets EP specifications. This setup provides hospital with facility meeting GMP standard...
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PMID: 20177835
PDF is available here.
PDF is available here.
Toxicology Letters (192)3 2010
Abstract
In order to reveal the mechanism of the decreased ability of learning and memory induced by chronic fluorosis, nicotinic acetylcholine receptors (nAChRs) and the pathway of extracellular signal regulated protein kinase (ERK1/2) were investigated by using the rats fed with different concentrations of...
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PMID: 19900517
PDF is available here.
PDF is available here.
Abstract
This study evaluated the effect of different parameters of erbium, chromium:yttrium-scandium-gallium-garnet (Er,Cr:YSGG) laser irradiation on enamel mineral loss in a simulated caries model. Forty-five enamel samples obtained from third molar teeth (3 mmx 3 mm) were randomly divided...
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PMID: 18787759
PDF is available here.
PDF is available here.
Journal of Oral Science (52)1 2010
Abstract
This study was done to assess the influence of the topical application of two different desensitizing agents on dentin permeability and dentinal tubule occlusion. Twenty-one rats provided 84 teeth: 36 for the in vitro and 48 for the in vivo investigation. The following agents were tested: Group 1, 2...
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PMID: 20339229
PDF is available here.
PDF is available here.
Abstract
These results will greatly contribute to our understanding of the effects of fluoride exposure on the physiological and biochemical functions of Takifugu and the toxicological mechanism of fluoride causing fluorosis in both fish and human....
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PMID: 20146379
PDF is available here.
PDF is available here.
Abstract
To evaluate in vitro the effect of fluoride therapies on the surface roughness of human dental enamel exposed to bleaching agents.
Sixty-six specimens obtained from 33 third molars were centrally cut, mounted on acrylic resin supports, polished, and submitted to baseline surface roughness readings (...
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PMID: 19907736
PDF is available here.
PDF is available here.
Pediatric Dentistry (32)5 2010
Abstract
These results show that casein phosphopeptide-amorphous calcium phosphate-containing paste has the ability to maintain the enamel surface; the combined use of CPP-ACP paste and fluoride enhances this ability, thereby reducing demineralization....
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PMID: 21070712
PDF is available here.
PDF is available here.
Operative Dentistry (35)3 2010
Abstract
The one-bottle self-etching adhesives and dentin desensitizers involved in the current clinical investigation could significantly relieve dentin hypersensitivity immediately and over the course of a month after treatment (except for Bifluorid 12 for tooth mechanical sensitivity). The placebo (water)...
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PMID: 20533627
PDF is available here.
PDF is available here.
Operative Dentistry (35)2 2010
Abstract
This study evaluated the influence of bleaching gel pH, the effect of applying remineralizing gels after bleaching and the effect of artificial saliva on enamel microhardness. Seventy bovine incisors were divided into three groups: Group 1 (n=10) received no bleaching procedure (control); Group 2 wa...
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PMID: 20420061
PDF is available here.
PDF is available here.
General dentistry (58)1 2010
Abstract
This investigation compared the effects of a fluoride dentifrice and toothpastes formulated with antimicrobial ingredients (stannous fluoride and triclosan/copolymer) on oral micro-organisms, including those found in samples taken from the human oral cavity. Microbiological techniques determined the...
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PMID: 20129893
PDF is available here.
PDF is available here.
Abstract
To measure the desensitizing benefits of an experimental stannous-containing sodium fluoride dentifrice versus a regular sodium fluoride negative control.
This study was a randomized, double-blind, parallel group, four-week clinical trial. Subjects reporting dentinal...
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PMID: 20098960
PDF is available here.
PDF is available here.
Abstract
It is generally accepted that the pain of dental hypersensitivity resulting from gum recession is from the movement of fluid within the exposed tubules of dentin, causing changes in pressure on the nerve within the pulpal cavity. One method of treating hypersensitivity is to occlude...
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PMID: 20158016
PDF is available here.
PDF is available here.
Caries Research (44)2 2010
Abstract
This study evaluated in vitro commercial desensitizing toothpastes with respect to the prevention of erosion and explored the effect of their agents alone or in combination with fluoride. Bovine enamel blocks were randomly allocated to five groups of 20 and exposed to: Sensodyne ProNamel (1,425 ppm...
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PMID: 20145397
PDF is available here.
PDF is available here.
Caries Research (44)1 2010
Abstract
This split-mouth study aimed to assess the efficacy of resin-infiltrated lesions covered by fluoride varnish (FV) versus FV treatment only of proximal lesions on deciduous molar teeth. The study lasted for 1 year. Children with 2 or more superficial proximal lesions on deciduous molar teeth detected...
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PMID: 20090327
PDF is available here.
PDF is available here.
Caries Research (44)2 2010
Abstract
While the clinical anticaries efficacy of fluoride toothpaste is now without question, our understanding of the relation of fluoride efficacy to brushing time and dentifrice quantity is limited. The aim of this in situ study was to determine how differences in brushing time and dentifrice quantity i...
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PMID: 20160441
PDF is available here.
PDF is available here.
Abstract
Surface imaging showed the dentifrice had coated the treated sample. Sub-surface information gained by preparing longitudinal cross-sections of the treated samples showed the tubule openings to be plugged, and EDX mapping of the cross-section confirmed enhanced strontium levels within the tubules se...
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PMID: 20669814
PDF is available here.
PDF is available here.
Abstract
Seventy-seven subjects completed this clinical study. Both subject groups exhibited significant cumulative reductions from baseline to Days 14, 28, and 56 in dentin hypersensitivity as measured by Schiff, Yeaple, and VAS (for the 8% strontium acetate group, p < or = 0.0001 for all time points; for t...
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PMID: 20669816
PDF is available here.
PDF is available here.
Abstract
Seventy-nine subjects completed this clinical study. Both subject groups exhibited reductions in dentin hypersensitivity directly after a single dab-on application. These reductions were significant across all measures for the test dentifrice. Between-treatment analyses showed the test dentifrice to...
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PMID: 20669815
PDF is available here.
PDF is available here.
Abstract
An 8% strontium acetate, 1040 ppm sodium fluoride-based dentifrice has been demonstrated in in vitro and in situ studies to provide deep and acid-resistant tubule occlusion. Clinical efficacy studies have shown instant and lasting dentin hypersensitivity relief from this dentifrice, which has recent...
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PMID: 20669817
PDF is available here.
PDF is available here.
Abstract
CTP provided a significant (p = 0.01) antiplaque effect versus CRT. The results are consistent with previously reported data for CTT. All three examiners demonstrated a strong correlation for this clinical study utilizing the MGMPI methodology. CONCLUSION: This clinical investigation examined the ef...
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PMID: 20527504
PDF is available here.
PDF is available here.
Abstract
The objective of these three clinical trials was to compare the impact of two commercial products, Colgate Total and Crest Pro-Health, on the formation of dental plaque over a 24-hour period of time. The studies utilized the Modified Gingival Margin Plaque Index (MGMPI), a validated and reliable cli...
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PMID: 21269038
PDF is available here.
PDF is available here.
Abstract
Abstract
To assess the efficacy ofa dentifrice containing 0.3% triclosan/2.0% PVM/MA copolymer/0.243% sodium fluoride for controlling established gingivitis and supragingival plaque relative to that of a dentifrice containing 0.454% stannous fluoride, sodium hexametaphosphate, and zinc lactate, and a dentifr...
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PMID: 21269039
PDF is available here.
PDF is available here.
Abstract
To compare the efficacy ofa dentifrice containing 0.3% triclosan, 2.0% PVM/MA copolymer, and 0.243% sodium fluoride in controlling established gingivitis and supragingival plaque to that of a commercially available dentifrice containing 0.454% stannous fluoride, sodium hexametaphosphate, and zinc la...
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PMID: 21269040
PDF is available here.
PDF is available here.
Abstract
This double-blind clinical study, conducted at the University of Puerto Rico, San Juan, Puerto Rico, was designed to compare the efficacy of two commercially available dentifrices for the control of supragingival plaque and gingivitis.
Qualifying adult male and female subjects from the San Juan, Pue...
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PMID: 21269041
PDF is available here.
PDF is available here.
Abstract
In vitro testing of antimicrobial agents is an important tool in the testing hierarchy, and may provide interesting insights into their potential clinical efficacy. Agents with demonstrable in vitro antimicrobial activity may be effective against the same microorganisms in vivo, whereas agents witho...
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PMID: 21269037
PDF is available here.
PDF is available here.
Abstract
These results indicate that lactate metabolism is impaired in critically ill horses and [LAC]deltaT can be a useful prognostic indicator in horses....
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PMID: 19925572
PDF is available here.
PDF is available here.
Abstract
Groups B and C showed significant increases in enamel microhardness following treatment (P < 0.001), whereas no statistically significant changes were observed in Groups A, D, or E (P > 0.05). One-way ANOVA of delta Vickers microhardness numbers (deltaVHN) revealed significant differences among grou...
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PMID: 20178219
PDF is available here.
PDF is available here.
Bulletin du cancer (96)11 2009
Abstract
The authors discuss the various roles of 18F-FDG PET/CT in the management of breast cancer. Roles of new tracers such as F-18 fluoro-L-thymidine (a marker of cell proliferation), 18-fluoro-17-B-estradiol (marker of estrogen receptor) and sodium fluoride (marker of bone matrix) are also mentioned. Th...
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PMID: 19758959
PDF is available here.
PDF is available here.
Dental update (36)7 2009
Abstract
The method of applying fluoride varnish is described and the evidence of its effectiveness in the prevention and control of caries is summarized.The application of fluoride varnish should be an integral part of caries preventive programmes. CLINICAL RELEVANCE: This paper describes how to apply fluor...
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PMID: 19810396
PDF is available here.
PDF is available here.
Molecular and Cellular Biochemistry (328)1-2 2009
Abstract
We used NaF and antimycin A as treatment agents to manipulate intracellular levels of InsPs. NaF is known to increase levels of higher InsPs by inhibiting InsPs phosphatases, a process that is reversed by antimycin A because InsPs kinases are inhibited as a result of depletion of cellular ATP pools....
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PMID: 19322641
PDF is available here.
PDF is available here.
Abstract
The mean percent area remineralization (+/-SD) was: bioerodible fluoridated resin 44.1 +/- 12.1; fluoride varnish 19.1 +/- 9.2; control 2.4 +/- 3.4. ANOVA indicated a significant variance among groups (P < 0.001). Tukey's multiple comparison test demonstrated the fluoridated resin to enhance reminer...
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PMID: 19824554
PDF is available here.
PDF is available here.
Archives of Oral Biology (54)8 2009
Abstract
This study aimed to analyse and compare the protective effect of buffered (pH 3.5) and native (pH 1.2) TiF(4) in comparison to NaF solutions of same pH on dentin erosion.
Bovine samples were pretreated with 1.50% TiF(4) or 2.02% NaF (both 0.48M F) solutions, each with...
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PMID: 19482262
PDF is available here.
PDF is available here.
Abstract
Brushing twice a day for 2 minutes with Fluor Kin antisarro effectively reduces supragingival calculus....
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PMID: 19587891
PDF is available here.
PDF is available here.
Abstract
A fluoride dose response was observed for the test dentifrices after 10 and 20 days of pH cycling, with test dentifrice C promoting the highest remineralization among the groups while both the MI Paste Plus and PreviDent systems provide the least remineralization (one-way ANOVA, SNK, P < 0.05). With...
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PMID: 19650601
PDF is available here.
PDF is available here.
Abstract
Significant differences resulted between the distilled water and fluoride-containing groups. Among the fluoride-containing groups, Group B demonstrated statistically low levels of enamel fluoride deposition and deltaVHN, while Group E statistically outperformed Group D. Among the groups with differe...
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PMID: 19650602
PDF is available here.
PDF is available here.
Archives of Toxicology (83)5 2009
Abstract
Long-term excessive fluoride intake is linked to skeletal disease. Skeletal health is influenced by the balance between bone formation and resorption of which osteoblast function is critical. The objectives of this study were to determine the effect of fluoride treatment on osteoblast proliferation,...
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PMID: 19009284
PDF is available here.
PDF is available here.
The Journal of Chemical Physics (130)13 2009
Abstract
We study ionenes that are short chains (six monomer units) in solutions of different counterions, with sodium as the coion by molecular dynamics simulations in explicit water. We explore the pair distributions of various atoms within the system at three different temperatures: T=278, 298, and 318 K....
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PMID: 19355776
PDF is available here.
PDF is available here.
Abstract
With increasing PO concentrations, the inhibition rates of collagen matrix degradation and the mineral loss were increased. Moreover, there was a positive statistical correlation between mineral loss and collagen matrix degradation, demonstrating that preservation of the collagen matrix would contri...
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PMID: 19626976
PDF is available here.
PDF is available here.
Dentistry today (28)3 2009
Abstract
American Journal of Dentistry (22 Spec No A) 2009
Abstract
68 subjects completed the 12-week study. No statistically significant differences from baseline scores were indicated at the Post-Scaling Examinations for either the Test Paste or Control Paste groups. Immediately following product application and 4 weeks after product application, subjects assigned...
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PMID: 19472556
PDF is available here.
PDF is available here.
American Journal of Dentistry (22 Spec No A) 2009
Abstract
The desensitizing paste containing 8% arginine and calcium carbonate did not have a significant effect on the surface roughness of the substrates tested. Although the 3D non-contact profilometry images showed slight roughness after toothbrushing followed by the use of the desensitizing paste, these...
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PMID: 19472558
PDF is available here.
PDF is available here.
Abstract
Participants were apparently knowledgeable about prevention, the need to limit sugary beverages, and the importance of brushing twice a day. They were not as knowledgeable about the need for flossing, providing fruits and vegetables to their children, the significance of not skipping a meal, or the...
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PMID: 19723433
PDF is available here.
PDF is available here.