Abstract
33 subjects were enrolled and completed the study. The adjusted mean volatile sulfur compound (VSC) levels were significantly lower in the SnF2 groups than the NaF groups, at both 24 (P < 0.01) and 28 (P < 0.001) hours post baseline time points. Tongue brushing did not provide additional statistical...
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PMID: 20718217
PDF is available here.
Abstract
This investigation compared the effects of a fluoride dentifrice and toothpastes formulated with antimicrobial ingredients (stannous fluoride and triclosan/copolymer) on oral micro-organisms, including those found in samples taken from the human oral cavity. Microbiological techniques determined the...
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PMID: 20129893
PDF is available here.
Abstract
To determine and compare the clinical performance of formulations containing 7.5% calcium sodium phosphosilicate (NovaMin), 5% potassium nitrate, and 0.4% stannous fluoride for the management of dentin hypersensitivity.
This was a single-center, randomized, double-blind, parallel-group design with a...
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PMID: 21207920
PDF is available here.
Abstract
The objective of these three clinical trials was to compare the impact of two commercial products, Colgate Total and Crest Pro-Health, on the formation of dental plaque over a 24-hour period of time. The studies utilized the Modified Gingival Margin Plaque Index (MGMPI), a validated and reliable cli...
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PMID: 21269038
PDF is available here.
Abstract
To assess the efficacy ofa dentifrice containing 0.3% triclosan/2.0% PVM/MA copolymer/0.243% sodium fluoride for controlling established gingivitis and supragingival plaque relative to that of a dentifrice containing 0.454% stannous fluoride, sodium hexametaphosphate, and zinc lactate, and a dentifr...
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PMID: 21269039
PDF is available here.
Abstract
To compare the efficacy ofa dentifrice containing 0.3% triclosan, 2.0% PVM/MA copolymer, and 0.243% sodium fluoride in controlling established gingivitis and supragingival plaque to that of a commercially available dentifrice containing 0.454% stannous fluoride, sodium hexametaphosphate, and zinc la...
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PMID: 21269040
PDF is available here.
Abstract
This double-blind clinical study, conducted at the University of Puerto Rico, San Juan, Puerto Rico, was designed to compare the efficacy of two commercially available dentifrices for the control of supragingival plaque and gingivitis.
Qualifying adult male and female subjects from the San Juan, Pue...
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PMID: 21269041
PDF is available here.
Abstract
In vitro testing of antimicrobial agents is an important tool in the testing hierarchy, and may provide interesting insights into their potential clinical efficacy. Agents with demonstrable in vitro antimicrobial activity may be effective against the same microorganisms in vivo, whereas agents witho...
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PMID: 21269037
PDF is available here.
Abstract
One hundred twelve specimens from bovine incisors were divided into eight groups: Group 1 (treated with 10% strontium chloride gel), Group 2 (treated with 2% sodium fluoride gel), Group 3 (treated with 2% stannous fluoride gel), Group 4 (treated with 5% potassium nitrate gel), Group 5 (treated with...
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PMID: 19903641
PDF is available here.
Abstract
Fluoride uptake by incipient erosive lesions treated with toothpastes containing NaF was quantitatively compared by DSIMS and found to be directly proportional to the fluoride concentration over the studied range (0-1400 ppm). Lesion repair observed in a single-treatment lesion rehardening model was...
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PMID: 20131678
PDF is available here.
Abstract
Twenty-seven subjects completed the study. The SnF2/SHMP dentifrice provided a statistically significant lower level of plaque area coverage compared to the AlF3/Chx dentifrice at all time points. For the SnF2/SHMP dentifrice, plaque coverage was 19.4% lower (p = 0.0043) at the A.M. pre-brush, 25.6%...
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PMID: 19591334
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Abstract
A good fluoride dose-response was established for EFU and REM, with NaF delivering greater EFU and REM than NaF-675, which was superior to NaF-0 (p < 0.05). The new dentifrice NaF also showed greater EFU and REM than AmF and SnNaF (p < 0.05). In EFU, AmF and SnNaF were as efficacious as NaF-675 and...
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PMID: 19591336
PDF is available here.
Abstract
It can be concluded that the frequent topical application of fluoride could be a successful treatment for incipient root carious lesions, irrespective of the type of fluoride treatment used....
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PMID: 19583040
PDF is available here.
Abstract
All 25 subjects completed the study. The SnF2/SHMP positive control dentifrice provided statistically significantly lower levels of plaque area coverage versus the NaF/KNO3 test dentifrice at each timepoint. For the SnF2/SHMP dentifrice, plaque coverage was 23.0% lower (p< 0.0001) at A.M. pre-brushi...
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PMID: 19279966
PDF is available here.
Abstract
ASF and EO mouthrinses exerted effective and similar plaque inhibition. The two dosages tested for ASF did not differ in plaque reduction. These findings, together with those from long-term trials, suggest that ASF and EO rinses may represent effective alternatives to CHX rinse as adjuncts to oral h...
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PMID: 18597599
PDF is available here.
Abstract
Stannous fluoride dentifrice was superior to triclosan dentifrice in plaque growth inhibition between toothbrushing. Both mouthrinses provided additional plaque prevention benefits when used with antimicrobial dentifrices. The cetylpyridinium chloride mouthrinse and stannous fluoride dentifrice regi...
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PMID: 18686773
PDF is available here.
Abstract
MICs of AmF / SnF(2) and CHX varied between 1 and 4 microg ml(-1), whereas those of NaF were 15 000 microg ml(-1). Statistically significant growth inhibition was detected after AmF / SnF(2) (OD(24 h) +/- SD 0.457 +/- 0.059) and CHX (0.175 +/- 0.065) in comparison with PBS (0.925 +/- 0.087) and NaF...
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PMID: 18410574
PDF is available here.
Abstract
IL-1beta, VEGF and PGE(2) levels were significantly lower in test compared to control group. Comparing first with second week of treatment, a greater decrease of IL-1beta and VEGF was evident in sample group during the second week. There was a lower decrease of IL-1beta and VEGF during the entire tr...
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PMID: 18496484
PDF is available here.
Abstract
Baseline Knoop Hardness (mean +/- S.D.) amounted to 403.1 +/- 39.4. Immediately after softening, mean SMH was reduced to 214.4 +/- 24.1 KHN. Rinsing with 250 ppm fluoride, milk or water after 5 minutes or 30 minutes intraoral exposure of softened samples had a significant effect on rehardening. The...
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PMID: 18578180
PDF is available here.
Abstract
It can be concluded that fluoride can be released from flossing with the tested SnF(2)-impregnated dental floss elevating salivary fluoride levels for at least 30 minutes. Use of this fluoride-containing dental floss offers an option for delivery of fluoride to individuals at risk for dental caries....
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PMID: 18416988
PDF is available here.
Abstract
The aim of this in situ study was to compare the protective effect of TiF4, SnF2 and NaF on the development of erosion-like lesions in human enamel. Fourteen human molars were each divided into 4 specimens, mounted on acrylic mouth appliances and worn by 7 volunteers for 9 days. In order to mimic a...
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PMID: 18160812
PDF is available here.
Abstract
The aim of the study was to evaluate the relevance of cations in different fluoride compounds for their effectiveness as anti-erosive agents. Human enamel samples underwent a de- and re-mineralisation procedure for 10 days. Erosive demineralisation was performed with 0.05 M citric acid (pH 2.3) 6 x...
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PMID: 18042984
PDF is available here.
Abstract
White Light DPIA Qualification--All 17 subjects completed the trial. The white light modification of DPIA successfully distinguished known variations in plaque coverage. Mean plaque coverage of the 12 anterior facial surfaces, as determined by the system for the four images, was: a) 0.07%; b) 11.44%...
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PMID: 18763686
PDF is available here.
Abstract
Twenty-five subjects completed the study. Twice daily use of the therapeutic night-time regimen resulted in a significant (p>0.001) 35% reduction of mean VSC levels in the overnight breath compared to the control regimen. CONCLUSION: One-day use of a night-time regimen consisting of a therapeutic pa...
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PMID: 18784853
PDF is available here.
Abstract
The purpose of this prospective, double-blinded, placebo-controlled clinical trial was to investigate the efficacy and tolerability of a novel gel containing 0.4% stannous fluoride (MedEquine) for the treatment of cutaneous bacterial infections in horses. Twenty privately owned horses diagnosed with...
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PMID: 17991163
PDF is available here.
Abstract
anova showed statistically significant differences between the treatments (F = 4.21, p = 0.02). A post hoc test showed that SnF(2) produced a statistically significantly lower PI than did NaF. CONCLUSION: SnF(2) in toothpaste may be effective in inhibiting plaque accumulation in the elderly....
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PMID: 17999737
PDF is available here.
Abstract
The maintenance of an effective level of oral hygiene is the cornerstone of all attempts to prevent and control periodontal disease, and yet the widespread prevalence of the disease indicates the inability of most people to maintain a level of plaque control commensurate with periodontal health. The...
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PMID: 17716293
PDF is available here.
Abstract
TiF(4) gave the best protection against acid attack. SnF(2) provided significant protection only after 2 min of acid exposure, while NaF had no significant protective effect....
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PMID: 18092200
PDF is available here.
Abstract
QLF indicated no enhancement of remineralization of white spot lesions by additional weekly brushing with amine fluoride gel. No inter-group differences emerged with regard to salivary bacterial counts. However, the oral hygiene of both groups improved, with a strong significance over time. CONCLUSI...
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PMID: 17851827
PDF is available here.
Abstract
Twice daily use of the SnF(2)/SHMP dentifrice over 6 months provided statistically significant anti-plaque and anti-gingivitis benefits relative to a negative control....
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PMID: 17645550
PDF is available here.
Abstract
A total of 334 subjects were evaluable. During run-in, average CAL relative to initial examination was 1.33 mm. Probing depth increased 0.95 mm. At year 2 in the treatment phase, attachment gain was 0.77 mm for the test group and 0.79 mm for the control group versus baseline. Probing depth decreased...
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PMID: 17668969
PDF is available here.
Abstract
The data provide further support for tooth brushing before meals. Results of this study further suggest the sodium hexametaphosphate containing paste could be used to provide significant erosion protection in susceptible individuals over that provided by conventional fluoride products....
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PMID: 17329006
PDF is available here.
Abstract
We conclude that 3 wk of use of AmF/SnF(2) rinse once daily does not result in a reduction of plaque formation or in a reduction of sucrose metabolism in buccal and interproximal plaque after discontinuing the rinse....
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PMID: 17451506
PDF is available here.
Abstract
All dentifrice supernates containing SLS were effective in detaching co-adhering bacteria from pellicles surfaces, except in combination with SnF(2). When hexametaphosphate was added immediate detachment was relatively low, but continued even during re-deposition. The re-deposition of streptococci a...
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PMID: 17097208
PDF is available here.
Abstract
Each tested antimicrobial agent when applied on an excisional wound with epithelial and connective tissue deficiency did not have a negative effect on the rate of wound closure. The best results were achieved with 1%CHX gel and Listerine....
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PMID: 17309591
PDF is available here.
Abstract
59 subjects, 29 in Study 1 and 30 in Study 2, were evaluable and included in the Week 2 analyses. Subjects ranged from 21-68 years of age. In each study, the positive control dentifrice statistically significantly (P < 0.0001) reduced stain scores following 2 weeks of brushing with median reductions...
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PMID: 17380809
PDF is available here.
Abstract
These results suggest that treatment of enamel with a TiF(4) solution, with or without pellicle removal, may provide protection for the enamel against acid attack....
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PMID: 17167265
PDF is available here.
Abstract
The aim of this study was to investigate the effectiveness of both waiting periods between acid exposure and tooth brushing and fluoride applications in preventing toothbrush abrasion of acid-softened enamel surfaces. The study, on 5 subjects, had an in situ crossover design with experimental period...
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PMID: 17284917
PDF is available here.
Abstract
Fifty-two and 58 subjects completed studies 1 and 2, respectively. In each study, there were no statistically significant differences in Lobene composite stain scores between the two treatment groups across all three visits. Both groups showed statistically significant reductions in Lobene composite...
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PMID: 17410949
PDF is available here.
Abstract
The SnF2 dentifrice was observed to produce statistically significant reductions in dental plaque, measuring 24.4% in the morning pre-brushing, and 27.9% in the afternoon assessment. Tooth brushing was observed to significantly reduce plaque on the teeth in the morning post-brushing for subjects usi...
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PMID: 17410952
PDF is available here.
Abstract
One-hundred and seventy-four subjects completed the study and were included in the data analysis. At Week 8, the overnight adjusted whole mouth plaque scores were statistically significantly lower in all other groups relative to the Wave + Total group (p < or = 0.030). Plaque scores were also statis...
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PMID: 18277739
PDF is available here.
Abstract
CLSM and SEM analyses showed that specimens treated with SnF2/HMP appeared to resist acid solubilization, evidenced by the absence of disclosed dentinal tubuli. The histo-tomographic observations in this study were in agreement with the hardness measurements. The superior surface protection of denti...
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PMID: 17508625
PDF is available here.
Abstract
Compared to the control group, the experimental dentifrice group had a mean calculus score statistically significantly lower at both three months (50%) and six months (55%) post-treatment (p<0.001). Compared to control scores, mean experimental dentifrice calculus scores at three and six months were...
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PMID: 17618324
PDF is available here.
Abstract
At the 6-month sampling occasion, the subjects using dentifrice with either amine fluoride-stannous fluoride or triclosan showed a tendency to lower MS scores in interdental plaque (p < 0.05). In saliva and in the 1- and 3-month plaque samples, no changes of MS were detected in any of the four group...
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PMID: 17977294
PDF is available here.
Abstract
The studies in this systematic review provide strong evidence of the antiplaque, antigingivitis effects of multiple agents. These results support the use of these agents as part of a typical oral hygiene regimen....
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PMID: 17138709
PDF is available here.
Abstract
Only the enamel samples treated with the fluoridated bleaching gel (group B) and with the amine fluoride gel (group C) exhibited significant fluoride acquisition. Thereby, both gels showed significantly lower uptake in series 1 as compared to series 2. Both KOH-soluble and structurally bound fluorid...
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PMID: 16472904
PDF is available here.
Abstract
All treatment strategies resulted in significant (p<0.05) improvements of all clinical parameters over the entire duration of the study. Inter-treatment differences were often encountered. The NC group nearly always showed significant smaller improvements than the two CHX groups. The differences bet...
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PMID: 16856902
PDF is available here.
Abstract
These results support the strong retention and lasting antimicrobial efficacy of high stabilized stannous fluoride/sodium hexametaphosphate dentifrices....
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PMID: 16820802
PDF is available here.
Abstract
I and etch II). Toothpaste was applied to the labial surfaces with a soft brush (four applications, each of 1-min duration), with gentle water rinsing between applications. Each subject had one pair of teeth treated with each of the test toothpastes. Enamel dissolution was examined by assessment of...
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PMID: 16776765
PDF is available here.
Abstract
I (n = 72 patients), SN identification was done with radioisotope marker of 400–3000 nm molecule size (tin colloid). In Group II (n = 50 patients) radioisotope marker of <100 nm molecule size (colloidal albumin) was used.
Methods
All the patients of both groups received the markers with a single...
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PMID: 16621427
PDF is available here.
Abstract
The aim of this examiner-blind, clinical monitoring was to observe long-existing white spot lesions over a period of 6 months and to evaluate the effectiveness of fluoridated toothpastes on these lesions. Thirty-nine subjects with at least one lesion participated in the study. They were randomly div...
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PMID: 16546854
PDF is available here.
Abstract
The aim of this study was to examine the effect of combined use of a toothpaste/mouthrinse containing amine fluoride/stannous fluoride (AmF/SnF2; meridol) on the development of white spot lesions, plaque, and gingivitis on maxillary anterior teeth in orthodontic patients. A prospective, randomized,...
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PMID: 16230329
PDF is available here.
Abstract
Undiluted Meridolmouth rinse killed most study strains within a few minutes. In ascending order, C. parapsilosis, C. tropicalis, C. albicans, C. glabrata, C. krusei and C. dubliniensis showed higher resistance against AmF/SnF2 than C. guilliermondii. CONCLUSION: AmF/SnF2 could be used as a potent ad...
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PMID: 16390468
PDF is available here.
Abstract
Fluoride levels in saliva correlated with time from tooth-brushing and with oral cavity rinsing. Toothbrushing with rinsing led to similar increase/decrease in fluoride level in saliva for both toothpastes. The use of toothpaste without rinsing vs rinsing produced a two-fold increase in the level of...
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PMID: 17469502
PDF is available here.
Abstract
The objectives of this study were to evaluate and compare the amount and pattern of fluoride release from teeth after topical application of 2% NaF, 8% SnF2 and 1.23% APF at different time intervals. The growth inhibitory effects of this released fluoride ion was assessed on mutans streptococci (MS)...
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PMID: 16683673
PDF is available here.
Abstract
The use of SnF(2) dentifrices results in gingivitis and plaque reduction when compared with a conventional dentifrice. The precise magnitude of this effect was difficult to assess because of a high level of heterogeneity in study outcomes....
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PMID: 16367849
PDF is available here.
Abstract
The proposed method holds promise for assessment of both immediate and retained antimicrobial actions of oral treatments against dental plaque in vivo....
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PMID: 16367850
PDF is available here.
Abstract
The purpose of this in vitro study was to compare the protective effect of TiF4, SnF2 and NaF (all 0.5 M F) on the development of erosion-like lesions in human dental enamel. Four enamel specimens from each of 6 extracted molars were polished and embedded in epoxy resin. The enamel surfaces of 3 spe...
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PMID: 16946614
PDF is available here.
Abstract
The aim of this study was to determine whether a tooth cream containing casein/calcium phosphate (CasCP) protects enamel against erosion. Sixty bovine enamel specimens were prepared for profilometry and distributed into five groups. Specimens were rinsed with artificial saliva interrupted by 1% citr...
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PMID: 16508274
PDF is available here.