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Bleomycin (2)
Articles on Bleomycin
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ABVD alone versus radiation-based therapy in limited-stage Hodgkin's lymphoma.
N Engl J Med 366(5):399-408 (2012) PMID 22149921
We randomly assigned 405 patients with previously untreated stage IA or IIA nonbulky Hodgkin's lymphoma to treatment with doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD) alone or to treatment with subtotal nodal radiation therapy, with or without ABVD therapy. Patients in the ABVD-only g... -
Predictive models for pulmonary function changes after radiotherapy for breast cancer and lymphoma.
Int J Radiat Oncol Biol Phys 82(2):e257-64 (2012) PMID 21621341
To propose multivariate predictive models for changes in pulmonary function tests (ΔPFTs) with respect to preradiotherapy (pre-RT) values in patients undergoing RT for breast cancer and lymphoma. A prospective study was designed to measure ΔPFTs of patients undergoi... -
Chemotherapy alone for early-stage Hodgkin's lymphoma.
N Engl J Med 366(5):470-1 (2012) PMID 22149920
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Ameloblastomas have already been treated successfully with intralesional chemotherapy in dogs, why not in humans?
Oral Oncol 48(2):e1 (2012) PMID 21821463
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Intensified chemotherapy for diffuse large B-cell lymphomas.
Lancet 378(9806):1828-9 (2011) PMID 22118432
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Modeling pulmonary fibrosis with bleomycin.
Curr Opin Pulm Med 17(5):355-61 (2011) PMID 21832918
We summarize the characteristics of the bleomycin animal model, the most commonly used model of pulmonary fibrosis, highlighting recent advances it has led us to despite its disadvantages. Repetitive intratracheal administration of bleomycin more effectively mimics the chronic aspect... -
To dive or not to dive with bleomycin: a practical algorithm.
Aviat Space Environ Med 82(8):814-8 (2011) PMID 21853861
Bleomycin is used in the treatment of different cancers, but possible side effects of interstitial pneumonitis and fibrosis are associated with increased concentrations of oxygen. Therefore, clinicians are reluctant to declare young people fit for scuba diving after bleomycin treatme... -
Progress toward improving animal models for idiopathic pulmonary fibrosis.
Am J Med Sci 341(6):444-9 (2011) PMID 21613932
Idiopathic pulmonary fibrosis (IPF) remains a disease with an unknown cause and a poor prognosis. Among attempts to define disease pathogenesis, animal models of experimental lung fibrosis have a prominent role. Commonly used models include exposure to bleomycin, silica, fluorescein... -
Direct leukocyte migration across pulmonary arterioles and venules into the perivascular interstitium of murine lungs during bleomycin injur...
Am J Pathol 178(6):2560-72 (2011) PMID 21641381 PMCID PMC3124021
We hypothesized that leukocytes also migrate across pulmonary arterioles and venules, which serve as alternative sites for leukocyte influx into the lung during acute lung injury and repair. Lung sections from C57BL/6J mice up to 14 days after intratracheal bleomycin (3.33 U/kg) or saline instillati... -
[Treatment strategy for central nervous system involvement in intravascular large B-cell lymphoma].
Brain Nerve 63(5):467-72 (2011) PMID 21515926
Intravascular large B-cell lymphoma (IVLBCL) is a distinct disease entity of non-Hodgkin lymphoma which is characterized in the current WHO classification by the selective growth of tumour cells in the lumina of small vessels of various organs. This rare disease entity has a high incidence of central...
