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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Nucleotides (1):
Recent article
Nucleotides
Abstract
In recent developments in chemistry and genetic engineering, the humble researcher dealing with the origin of life finds her(him)self in a grey area of tackling something that even does not yet have a clear definition agreed upon. A series of chemical steps is described to be conside...
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PMID: 21641557
PDF is available here.
PDF is available here.
| < More recent | Older article > |
Abstract
We studied how nucleotides bind to PAN. Although PAN has six identical subunits, it binds ATPs in pairs, and its subunits exhibit three conformational states with high, low, or no affinity for ATP. When PAN binds two ATPγS molecules or two ATPγS plus two ADP molecules, it is maximally active in bi...
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PMID: 21335235
PDF is available here.
PDF is available here.
Journal of Molecular Biology (405)3 2011
Abstract
We report a fluorescence-based assay for measuring the real-time kinetics of single-nucleotide incorporation during transcription elongation. The fluorescent adenine analogue 2-aminopurine was incorporated at various single positions in the template or the nontemplate strand of the promoter-free elo...
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PMID: 21035457
PDF is available here.
PDF is available here.
Abstract
We have recently demonstrated that the T. brucei telomere structure plays an essential role in regulation of surface antigen gene expression, which is critical for T. brucei pathogenesis. However, T. brucei telomere structure has not been extensively studied due to the limitation of methods for anal...
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PMID: 21307825
PDF is available here.
PDF is available here.
Abstract
We employed the use of hydrophilic interaction liquid chromatography-mass spectrometry (HILIC-MS) in a focused metabolomic study of sugar-nucleotides relevant to the biosynthesis of highly novel carbohydrate modifications on the flagellin of Campylobacter sp. We exploited the unique selectivity of t...
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PMID: 19882128
PDF is available here.
PDF is available here.
Cancer Science (101)11 2010
Abstract
We showed that the overexpression of full-length PGK-1 in Lewis lung carcinoma (LLC-1) can reduce tumor growth in vivo by downregulation of COX-2 expression. Phosphoglycerate kinase 1 has two functional domains: a catalytic domain (CD); and a nucleotide-binding domain (NBD). To identify the function...
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PMID: 20731664
PDF is available here.
PDF is available here.
Abstract
We succeeded in the synthesis of triplex-forming oligonucleotides (TFOs) that contain a deoxyribonucleotide (Py) bearing a 2-pyridine nucleobase or the 2',4'-BNA congener (Py(B)). By UV melting experiments, it was found that 2-pyridine was a very promising nucleobase for the sequence-selective recog...
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PMID: 20648389
PDF is available here.
PDF is available here.
Abstract
The strain-promoted "double-click" (SPDC) reaction using Sondheimer diyne, a novel convergent method conjugating three molecules spontaneously, has enabled us to readily modify an azido-biomolecule with a small reporter azido-molecule.
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PMID: 20657923
PDF is available here.
PDF is available here.
Kidney International (78)10 2010
Abstract
Kidney International (78)10 2010
Abstract
Kidney International (67) 2010
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Kidney International (78)10 2010
Abstract
Kidney International (78)10 2010
Abstract
Kidney International (78)10 2010
Abstract
Kidney International (78)10 2010
Abstract
Kidney International (78)10 2010
Abstract
Kidney International (78)10 2010
Abstract
Kidney International (76) 2010
Abstract
Kidney International (78)10 2010
Abstract
Kidney International (78)10 2010
Abstract
Kidney International (78)10 2010
Abstract
Kidney International (78)10 2010
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Kidney International (78)10 2010
Abstract
Kidney International (78)10 2010
Abstract
Journal of Chromatography A (1217)34 2010
Abstract
An ion-pairing reversed-phase liquid chromatography-mass spectrometry (IP-RP-LC-MS) was developed for the determination of nucleotides, nucleosides and their transformation products in Cordyceps. Perfluorinated carboxylic acid, namely pentadecafluorooctanoic acid (PDFOA, 0.25mM), was used as volatil...
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PMID: 20637470
PDF is available here.
PDF is available here.
Abstract
We describe a standardized approach for searching potent and selective inhibitors of glycosyltransferases by high throughput quantitative MALDI-TOFMS-based screening of focused compound libraries constructed by 1,3-dipolar cycloaddition of the desired azidosugar nucleotides with various alkynes. An...
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PMID: 20684602
PDF is available here.
PDF is available here.
Journal of Biological Chemistry (285)33 2010
Abstract
The nucleotide state of actin (ATP, ADP-P(i), or ADP) is known to impact its interactions with other actin molecules upon polymerization as well as with multiple actin binding proteins both in the monomeric and filamentous states of actin. Recently, molecular dynamics simulations predicted that a se...
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PMID: 20530485
PDF is available here.
PDF is available here.
Abstract
RNA interference pathways can involve amplification of secondary siRNAs by RNA-dependent RNA polymerases. In plants, RDR6-dependent secondary siRNAs arise from transcripts targeted by some microRNAs (miRNAs). Here, Arabidopsis thaliana secondary siRNAs from mRNA as well as trans-acti...
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PMID: 20562854
PDF is available here.
PDF is available here.
Abstract
We previously confirmed that they conferred GCV resistance to recombinant baculoviruses (Nakano et al., J. Virol. Methods 161:223-230, 2009). Six characterized mutations, including a previously reported one that encodes a GCV-sensitive kinase-activity mutant (Isegawa et al., J. Clin. Virol. 44:15-19...
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PMID: 20083192
PDF is available here.
PDF is available here.
Abstract
We have recently shown that the nucleotide accessibility in double-stranded DNA molecules strongly depends on sequence context and can be predicted using neighbor information. In this work, we investigate statistics, neighbor-dependence and predictability of nucleotide solvent accessibility for vari...
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PMID: 20470873
PDF is available here.
PDF is available here.
Abstract
We report that two methyltransferases, RsmB and RsmF, are responsible for all four 5-methylcytidine (m(5)C) modifications in 16S rRNA of Thermus thermophilus. Like Escherichia coli RsmB, T. thermophilus RsmB produces m(5)C967. In contrast to E. coli RsmF, which introduces a single m(5)C1407 modifica...
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PMID: 20558545
PDF is available here.
PDF is available here.
Abstract
We use an algorithm now commonly used in microbial ecology, UniFrac, to cluster 175 genomes spanning all three domains of life based on the phylogenetic relationships among their complete tRNA pools. We find that the overall pattern of similarities and differences in the tRNA pools recaptures univer...
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PMID: 20558546
PDF is available here.
PDF is available here.
Abstract
We have established a strategy to produce and purify recombinant farnesylated guanylate-binding protein 1 (hGBP1), a dynamin-related large GTPase. Our system is based on the coexpression of hGBP1 with the two subunits of human farnesyltransferase in Escherichia coli and a chromatographic separation...
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PMID: 20348589
PDF is available here.
PDF is available here.
Abstract
We characterize the integrated response of a rat host to the liver fluke Fasciola hepatica using a combination of (1)H nuclear magnetic resonance spectroscopic profiles (liver, kidney, intestine, brain, spleen, plasma, urine, feces) and multiplex cytokine markers of systemic inflammation. Multivaria...
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PMID: 20664642
PDF is available here.
PDF is available here.
Journal of Biological Chemistry (285)30 2010
Abstract
We have previously shown that the mutagenic potential of DinB is regulated by the DNA damage response protein UmuD(2). In the current study, we employ a pre-steady-state fluorescence approach to gain a mechanistic understanding of DinB regulation by UmuD(2). Our results suggest that DinB, like its m...
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PMID: 20467052
PDF is available here.
PDF is available here.
Bioinformatics (26)14 2010
Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology.
Abstract
We describe a novel algorithm (Iterative Correction of Reference Nucleotides) that iteratively aligns deep coverage of short sequencing reads to correct errors in reference genome sequences and evaluate their accuracy.
Using Plasmodium falciparum (81% A + T content) as an extreme exa...
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PMID: 20562415
PDF is available here.
PDF is available here.
Bioinformatics (26)14 2010
Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology.
Abstract
We describe a novel algorithm (Iterative Correction of Reference Nucleotides) that iteratively aligns deep coverage of short sequencing reads to correct errors in reference genome sequences and evaluate their accuracy.
Using Plasmodium falciparum (81% A + T content) as an extreme exa...
|
PMID: 20562415
PDF is available here.
PDF is available here.
Bioinformatics (26)14 2010
Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology.
Abstract
We describe a novel algorithm (Iterative Correction of Reference Nucleotides) that iteratively aligns deep coverage of short sequencing reads to correct errors in reference genome sequences and evaluate their accuracy.
Using Plasmodium falciparum (81% A + T content) as an extreme exa...
|
PMID: 20562415
PDF is available here.
PDF is available here.
Bioinformatics (26)14 2010
Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology.
Abstract
We describe a novel algorithm (Iterative Correction of Reference Nucleotides) that iteratively aligns deep coverage of short sequencing reads to correct errors in reference genome sequences and evaluate their accuracy.
Using Plasmodium falciparum (81% A + T content) as an extreme exa...
|
PMID: 20562415
PDF is available here.
PDF is available here.
Bioinformatics (26)14 2010
Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology.
Abstract
We describe a novel algorithm (Iterative Correction of Reference Nucleotides) that iteratively aligns deep coverage of short sequencing reads to correct errors in reference genome sequences and evaluate their accuracy.
Using Plasmodium falciparum (81% A + T content) as an extreme exa...
|
PMID: 20562415
PDF is available here.
PDF is available here.
Bioinformatics (26)14 2010
Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology.
Abstract
We describe a novel algorithm (Iterative Correction of Reference Nucleotides) that iteratively aligns deep coverage of short sequencing reads to correct errors in reference genome sequences and evaluate their accuracy.
Using Plasmodium falciparum (81% A + T content) as an extreme exa...
|
PMID: 20562415
PDF is available here.
PDF is available here.
Bioinformatics (26)14 2010
Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology.
Abstract
We describe a novel algorithm (Iterative Correction of Reference Nucleotides) that iteratively aligns deep coverage of short sequencing reads to correct errors in reference genome sequences and evaluate their accuracy.
Using Plasmodium falciparum (81% A + T content) as an extreme exa...
|
PMID: 20562415
PDF is available here.
PDF is available here.
Bioinformatics (26)14 2010
Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology.
Abstract
We describe a novel algorithm (Iterative Correction of Reference Nucleotides) that iteratively aligns deep coverage of short sequencing reads to correct errors in reference genome sequences and evaluate their accuracy.
Using Plasmodium falciparum (81% A + T content) as an extreme exa...
|
PMID: 20562415
PDF is available here.
PDF is available here.
Bioinformatics (26)14 2010
Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology.
Abstract
We describe a novel algorithm (Iterative Correction of Reference Nucleotides) that iteratively aligns deep coverage of short sequencing reads to correct errors in reference genome sequences and evaluate their accuracy.
Using Plasmodium falciparum (81% A + T content) as an extreme exa...
|
PMID: 20562415
PDF is available here.
PDF is available here.
Bioinformatics (26)14 2010
Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology.
Abstract
We describe a novel algorithm (Iterative Correction of Reference Nucleotides) that iteratively aligns deep coverage of short sequencing reads to correct errors in reference genome sequences and evaluate their accuracy.
Using Plasmodium falciparum (81% A + T content) as an extreme exa...
|
PMID: 20562415
PDF is available here.
PDF is available here.
Bioinformatics (26)14 2010
Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology.
Abstract
We describe a novel algorithm (Iterative Correction of Reference Nucleotides) that iteratively aligns deep coverage of short sequencing reads to correct errors in reference genome sequences and evaluate their accuracy.
Using Plasmodium falciparum (81% A + T content) as an extreme exa...
|
PMID: 20562415
PDF is available here.
PDF is available here.
Bioinformatics (26)14 2010
Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology.
Abstract
We describe a novel algorithm (Iterative Correction of Reference Nucleotides) that iteratively aligns deep coverage of short sequencing reads to correct errors in reference genome sequences and evaluate their accuracy.
Using Plasmodium falciparum (81% A + T content) as an extreme exa...
|
PMID: 20562415
PDF is available here.
PDF is available here.
Bioinformatics (26)14 2010
Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology.
Abstract
We describe a novel algorithm (Iterative Correction of Reference Nucleotides) that iteratively aligns deep coverage of short sequencing reads to correct errors in reference genome sequences and evaluate their accuracy.
Using Plasmodium falciparum (81% A + T content) as an extreme exa...
|
PMID: 20562415
PDF is available here.
PDF is available here.
Bioinformatics (26)14 2010
Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology.
Abstract
We describe a novel algorithm (Iterative Correction of Reference Nucleotides) that iteratively aligns deep coverage of short sequencing reads to correct errors in reference genome sequences and evaluate their accuracy.
Using Plasmodium falciparum (81% A + T content) as an extreme exa...
|
PMID: 20562415
PDF is available here.
PDF is available here.
Bioinformatics (26)14 2010
Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology.
Abstract
We describe a novel algorithm (Iterative Correction of Reference Nucleotides) that iteratively aligns deep coverage of short sequencing reads to correct errors in reference genome sequences and evaluate their accuracy.
Using Plasmodium falciparum (81% A + T content) as an extreme exa...
|
PMID: 20562415
PDF is available here.
PDF is available here.
Bioinformatics (26)14 2010
Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology.
Abstract
We describe a novel algorithm (Iterative Correction of Reference Nucleotides) that iteratively aligns deep coverage of short sequencing reads to correct errors in reference genome sequences and evaluate their accuracy.
Using Plasmodium falciparum (81% A + T content) as an extreme exa...
|
PMID: 20562415
PDF is available here.
PDF is available here.
Bioinformatics (26)14 2010
Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology.
Abstract
We describe a novel algorithm (Iterative Correction of Reference Nucleotides) that iteratively aligns deep coverage of short sequencing reads to correct errors in reference genome sequences and evaluate their accuracy.
Using Plasmodium falciparum (81% A + T content) as an extreme exa...
|
PMID: 20562415
PDF is available here.
PDF is available here.
Bioinformatics (26)14 2010
Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology.
Abstract
We describe a novel algorithm (Iterative Correction of Reference Nucleotides) that iteratively aligns deep coverage of short sequencing reads to correct errors in reference genome sequences and evaluate their accuracy.
Using Plasmodium falciparum (81% A + T content) as an extreme exa...
|
PMID: 20562415
PDF is available here.
PDF is available here.
Bioinformatics (26)14 2010
Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology.
Abstract
We describe a novel algorithm (Iterative Correction of Reference Nucleotides) that iteratively aligns deep coverage of short sequencing reads to correct errors in reference genome sequences and evaluate their accuracy.
Using Plasmodium falciparum (81% A + T content) as an extreme exa...
|
PMID: 20562415
PDF is available here.
PDF is available here.
Bioinformatics (26)14 2010
Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology.
Abstract
We describe a novel algorithm (Iterative Correction of Reference Nucleotides) that iteratively aligns deep coverage of short sequencing reads to correct errors in reference genome sequences and evaluate their accuracy.
Using Plasmodium falciparum (81% A + T content) as an extreme exa...
|
PMID: 20562415
PDF is available here.
PDF is available here.
Bioinformatics (26)14 2010
Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology.
Abstract
We describe a novel algorithm (Iterative Correction of Reference Nucleotides) that iteratively aligns deep coverage of short sequencing reads to correct errors in reference genome sequences and evaluate their accuracy.
Using Plasmodium falciparum (81% A + T content) as an extreme exa...
|
PMID: 20562415
PDF is available here.
PDF is available here.
Bioinformatics (26)14 2010
Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology.
Abstract
We describe a novel algorithm (Iterative Correction of Reference Nucleotides) that iteratively aligns deep coverage of short sequencing reads to correct errors in reference genome sequences and evaluate their accuracy.
Using Plasmodium falciparum (81% A + T content) as an extreme exa...
|
PMID: 20562415
PDF is available here.
PDF is available here.
Bioinformatics (26)14 2010
Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology.
Abstract
We describe a novel algorithm (Iterative Correction of Reference Nucleotides) that iteratively aligns deep coverage of short sequencing reads to correct errors in reference genome sequences and evaluate their accuracy.
Using Plasmodium falciparum (81% A + T content) as an extreme exa...
|
PMID: 20562415
PDF is available here.
PDF is available here.
Bioinformatics (26)14 2010
Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology.
Abstract
We describe a novel algorithm (Iterative Correction of Reference Nucleotides) that iteratively aligns deep coverage of short sequencing reads to correct errors in reference genome sequences and evaluate their accuracy.
Using Plasmodium falciparum (81% A + T content) as an extreme exa...
|
PMID: 20562415
PDF is available here.
PDF is available here.
Bioinformatics (26)14 2010
Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology.
Abstract
We describe a novel algorithm (Iterative Correction of Reference Nucleotides) that iteratively aligns deep coverage of short sequencing reads to correct errors in reference genome sequences and evaluate their accuracy.
Using Plasmodium falciparum (81% A + T content) as an extreme exa...
|
PMID: 20562415
PDF is available here.
PDF is available here.