Find your PDFs fast.
Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Polysaccharides (17):
Recent article
Polysaccharides
Journal of Neuroscience (31)31 2011
Abstract
We examine the effect of endotoxin-induced inflammation on Ox neuron biology and LMA in rats. Our results demonstrate a vital role for diminished Ox signaling in mediating inflammation-induced lethargy. This work defines a specific population of inflammation-sensitive, arousal-associated Ox neurons...
|
PMID: 21813697
PDF is available here.
PDF is available here.
| < More recent | Older article > |
Abstract
We lack insight into the impact of structure and size for their capacity to affect immune responses.
This study addresses the importance of chemical structure, size, origin and presence of contaminants for the capacity of both dietary and non-food NSP to modulate DC. Of 28 NSP produc...
|
PMID: 20938988
PDF is available here.
PDF is available here.
Abstract
Pretreatment of rice husk by alkaline peroxide assisted wet air oxidation (APAWAO) approach was investigated with the aim to enhance the enzymatic convertibility of cellulose in pretreated rice husk. Rice husk was presoaked overnight in 1% (w/v) H(2) O(2) solution (pH adjusted to 11....
|
PMID: 21538972
PDF is available here.
PDF is available here.
Abstract
We describe a multi-step chromatographic strategy required to isolate three new endo-β-glucanases (denoted EG V, EG VI, and EG VII) with activity against cereal mixed-linkage β-glucans from the thermophilic fungus Talaromyces emersonii. This work also illustrates the challenges frequently involved...
|
PMID: 20978986
PDF is available here.
PDF is available here.
Abstract
We have witnessed critical advances in genomics and proteomics which contributed to delineate the "tumor progression signature". This includes the altered expression of genes and proteins not only in tumor cells, but also in tumor-associated stromal, endothelial, and immune cells. Adding more comple...
|
PMID: 20941621
PDF is available here.
PDF is available here.
Abstract
We have used the Mammalian Glycan Array to determine the specific affinities of these proteins. This was correlated with binding protein expression induced by different prebiotics including HMO. Half of the F1SBPs in B. infantis were determined to bind mammalian oligosaccharides. Their affinities in...
|
PMID: 21423604
PDF is available here.
PDF is available here.
BMC Systems Biology (5)Suppl 1 2011
Abstract
We analyzed both the RNA profile, to reveal changes in gene expression, and the glycan profile, to identify changes in glycan structures, between 51 cell samples of four parental somatic cell (SC) lines from amniotic mesodermal, placental artery endothelial, and uterine endometrium sources, fetal lu...
|
PMID: 21689476
PDF is available here.
PDF is available here.
Abstract
To examine the usefulness of contrast-enhanced color Doppler ultrasonography (CDU) in differentiating between invasive and noninvasive gestational trophoblastic disease (GTD).
|
PMID: 21682118
PDF is available here.
PDF is available here.
Abstract
We have verified that such heterogeneity exists in PCI purified from single individuals, and that individuals of two different ethnicities possess a similar PCI pattern, verifying that the micro-heterogeneity is conserved among humans. Furthermore, we have provided experimental evidence that PCI in...
|
PMID: 21056543
PDF is available here.
PDF is available here.
Biocontrol Science (15)4 2010
Abstract
We conclude that KE possesses potent anti PRV activity, and the candidate responsible for the antiviral property was the polysaccharide fraction....
|
PMID: 21212504
PDF is available here.
PDF is available here.
Biomaterials (31)34 2010
Abstract
The long-term success of orthopedic implants may be compromised by defective osseointegration and bacterial infection. An effective approach to minimize implant failure would be to modify the surface of the implant to make it habitable for bone-forming cells and anti-infective at the same time. In t...
|
PMID: 20800276
PDF is available here.
PDF is available here.
Molecular BioSystems (6)12 2010
Abstract
The majority of molecular processes in higher organisms are performed by various proteins and are thus determined by genes that encode these proteins. However, a significant structural component of at least half of all cellular proteins is not a polypeptide encoded by a single gene,...
|
PMID: 20957246
PDF is available here.
PDF is available here.
Abstract
The aim of this study was to investigate the effect of lubricant eyedrops containing propylene glycol 400 (PEG) and polyethylene glycol (PG) with hydroxypropyl guar (HP-guar) as a gelling agent on the precorneal mucous layer in vivo.
Sixteen New Zealand white rabbits were randomly assigned to 1 of 4...
|
PMID: 20805744
PDF is available here.
PDF is available here.
Abstract
We report in this paper the first chemoenzymatic synthesis of homogeneous CD52 glycoforms carrying both N- and O-glycans. The synthetic strategy consists of two key steps: monosaccharide primers GlcNAc and GalNAc were first installed at the pre-determined N- and O-glycosylation sites by a facile sol...
|
PMID: 20848033
PDF is available here.
PDF is available here.
Journal of Biological Chemistry (285)45 2010
Abstract
We found that the first fibronectin type III repeat (FN1) of NCAM is required for the polysialylation of N-glycans on the adjacent Ig5 domain, and we proposed that the polysialyltransferases recognize specific sequences in FN1 to position themselves for Ig5 N-glycan polysialylation. Other studies id...
|
PMID: 20805222
PDF is available here.
PDF is available here.
Abstract
Fruit of Zizyphus jujuba Mill, a traditional Chinese herb widely consumed in Asian countries, has been reported to possess several vital biological activities. This study intends to develop an appropriate analytical method for isolation of polysaccharides from Z. jujuba fruits and evaluate their ant...
|
PMID: 20615429
PDF is available here.
PDF is available here.
Abstract
Abstract
We demonstrate that effective identification and characterization of both peptides and glycopeptides mixtures, and their constituent glycan structures, can be achieved from a single sample injection event....
|
PMID: 19882125
PDF is available here.
PDF is available here.
Abstract
We present an automated tool, SimGlycan, for this purpose, which accepts raw/standard MS data files as input and characterizes the associated glycan structure with high accuracy using database searching and scoring techniques. Not only does it predict the glycan structure using an MS/MS database sea...
|
PMID: 19882135
PDF is available here.
PDF is available here.
Hospital practice (1995) (38)4 2010
Abstract
Many acutely ill medical patients are at significant risk for developing venous thromboembolism (VTE) during hospitalization. Venous thromboembolism risk arises from both the presenting clinical condition as well as predisposing risk factors, such as advanced age. Thromboprophylaxis is underprescrib...
|
PMID: 21068523
PDF is available here.
PDF is available here.
Abstract
We give an overview of strategies for glycan isolation, derivatization, fractionation, immobilization and structural characterization. Detection methods such as fluorescence analysis and surface plasmon resonance are summarized. The importance of glycan density and multivalency is discussed. Further...
|
PMID: 20973647
PDF is available here.
PDF is available here.
Abstract
Our results showed that the high polarity fraction of the hot water extract exhibited stimulatory effects on PBMC proliferation as shown in [methyl-(3)H]-thymidine incorporation assay. In an attempt to isolate the active components responsible for the activities, further partition with ethyl acetate...
|
PMID: 20609432
PDF is available here.
PDF is available here.
Abstract
Longan (Dimocarpus longan Lour.) is used as a traditional edible and medicinal material in China. In this paper, the effects of polysaccharides from longan pulp with ultrasonic extraction (UELP) on the radicals scavenging, immunity-modulatory and antitumor activities in S180 tumor mice models were i...
|
PMID: 20685359
PDF is available here.
PDF is available here.
Abstract
To research the microemulsion preparation of Ganoderma lucidum polysaccharides and triterpenes and investigate its properities. Evaluate the effects of polysaccharides and triterpenes microemulsions against transplant tumor growth.
The microemulsion formula was optimized by constructing the pseudo-t...
|
PMID: 21246817
PDF is available here.
PDF is available here.
Abstract
We also sought post priori to determine if there was a difference in effect based on percentage of ventilatory threshold (VT) at which the subjects cycled to exhaustion. Fifteen trained male and female cyclists exercised on 2 separate occasions at intensities alternating between 45 and 70% VO2max fo...
|
PMID: 20733521
PDF is available here.
PDF is available here.
New Phytologist (188)1 2010
Abstract
• Brown algal cell walls share some components with plants (cellulose) and animals (sulfated fucans), but they also contain some unique polysaccharides (alginates). Analysis of the Ectocarpus genome provides a unique opportunity to decipher the molecular bases of these crucial metabolisms. • An...
|
PMID: 20618907
PDF is available here.
PDF is available here.
Abstract
We previously isolated the novel heteropolysaccharide maitake Z-fraction (MZF) from the maitake mushroom (Grifola frondosa), and demonstrated that MZF significantly inhibited tumor growth by inducing cell-mediated immunity. In this study, we demonstrated that MZF upregulated the expression of CD80,...
|
PMID: 20563803
PDF is available here.
PDF is available here.
Bioresource Technology (101)19 2010
Abstract
Modified fibres with high-cellulose content were obtained with two new bacterial xylanases from families 11 and 5. These xylanases were applied separately or simultaneously in a complete ECF (Elemental Chlorine Free) bleaching sequence. Both xylanases improved delignification and ble...
|
PMID: 20576566
PDF is available here.
PDF is available here.
Abstract
We investigated macrophage activation by fucoidan from Laminaria angustata var. longissima in a murine macrophage cell line, RAW 264.7. The ratio of the chemical composition of the fucoidan was L-fucose:D-galactose:D-glucose:D-xylose:uronic acid:sulfate=1.00:0.54:0.08:0.08:0.64:0.87. The fucoidan in...
|
PMID: 20834144
PDF is available here.
PDF is available here.
Abstract
Several key enzymes in lignin biosynthesis of Populus have been down-regulated by transgenic approaches to investigate their role in wood lignification and to explore their potential for lignin modification. Cinnamate 4-hydroxylase is an enzyme in the early phenylpropanoid pathway that has not yet b...
|
PMID: 20831275
PDF is available here.
PDF is available here.
Nanotechnology (21)35 2010
Characterization of endocytosis and exocytosis of cationic nanoparticles in airway epithelium cells.
Abstract
We found that clathrin pathway is implied in their endocytosis. Cholesterol depletion increased NP uptake by 300% and this phenomenon was explained by the fact that cholesterol depletion totally blocked NP exocytosis. These results suggest that these cationic NPs interact with anionic sites, are qui...
|
PMID: 20689164
PDF is available here.
PDF is available here.
Abstract
Wound sealants provide an excellent alternative for closing surgical and non-surgical wounds, as well as stopping external bleeding for prehospital trauma injuries. Numerous biomaterials have been investigated to address specific requirements for their use as suitable wound sealants. This article fo...
|
PMID: 20822387
PDF is available here.
PDF is available here.
Orthopedics (33)9 2010
Abstract
Venous thromboembolism remains the most common cause of hospital readmission and death after total joint arthroplasty. The 2008 American College of Chest Physicians (ACCP) guidelines, based on prospective randomized clinical trials with a venography endpoint, endorse the use of low-molecular-weight...
|
PMID: 20839678
PDF is available here.
PDF is available here.
Abstract
Heparin-induced thrombocytopenia (HIT) is a significant cause of morbidity and mortality in hospitalized patients, due to life and limb-threatening thrombosis. Prompt recognition, laboratory testing, and alternate anticoagulation are essential. At present, HIT remains an underdiagnosed and undertrea...
|
PMID: 20601872
PDF is available here.
PDF is available here.
Abstract
To study the effect of light quality on growth, polysaccharides content of Ganoderma lucidum.
G. lucidum was planted under different light qualities. The growth of G. lucidum was observed and polysaccharides content was determined in different growth periods.
There were significant differences in th...
|
PMID: 21137329
PDF is available here.
PDF is available here.
Abstract
We report a new approach to identify carbohydrate-targeting serum biomarkers, termed isotopic glycosidase elution and labeling on lectin-column chromatography (IGEL). This technology is based on glycan structure-specific enrichment of glycopeptides by lectin-column chromatography and site-directed t...
|
PMID: 20811073
PDF is available here.
PDF is available here.
Abstract
To examine the potential use of hemicellulose hydrolysate (HH) for the production of chitosan by Rhizopus oryzae and investigate the influence of contents in HH on mycelia growth and chitosan synthesis.
Compared to xylose medium, HH enhanced mycelia growth, chitosan content and production of R. oryz...
|
PMID: 20636326
PDF is available here.
PDF is available here.
Applied Spectroscopy (64)9 2010
Abstract
X-ray diffraction, scanning electron microscopy (SEM), and solid-state cross-polarization magic-angle-spinning (CP/MAS) (13)C-NMR spectroscopy were applied to determine changes over time in the morphology and crystallinity of lime wood (Tilia cordata Miller) generated by the soft-rot fungi. Wood sam...
|
PMID: 20828443
PDF is available here.
PDF is available here.
Abstract
An efficient short protocol for the preparation of N-perfluoroacylated glycals of neuraminic acid, by simple short treatment of differently protected N-acetylneuraminic acid with perfluorinated anhydrides in acetonitrile at 135 degrees C, is reported, together with a rationalitazion of the reaction...
|
PMID: 20559590
PDF is available here.
PDF is available here.
Abstract
Sialic acids are ubiquitously found on the surface of all vertebrate cells at the extremities of glycan chains and widely exploited by viruses and bacteria to enter host cells. Carbohydrate-bearing receptors are equally important for host cell invasion by the obligate intracellular protozoan parasit...
|
PMID: 20430033
PDF is available here.
PDF is available here.
Abstract
Classical swine fever virus (CSFV) outer surface E2 glycoprotein represents an important target to induce protective immunization during infection but the influence of N-glycosylation pattern in antigenicity is yet unclear. In the present work, the N-glycosylation of the E2-CSFV extracellular domain...
|
PMID: 20460099
PDF is available here.
PDF is available here.
Abstract
We genetically introduced an additional N-glycosylation sequon into HEXA, which caused amino acid substitutions (S51 to N and A53 to T) at homologous positions to N84 and T86 in the beta-subunit. The mutant HexA (NgHexA) obtained from a Chinese hamster ovary (CHO) cell line co-expressing the mutated...
|
PMID: 20571546
PDF is available here.
PDF is available here.
Abstract
Mutagenic properties of water soluble polysaccharides (WSPS) extracted from Acorus calamus L. have been studied. Neither a single intravenous injection nor a course intraperitoneal introduction of WSPS in a dose of 1/2 LD50 to mice of the CBA/CaLac line increases the level of cytogenetic disorders i...
|
PMID: 20919559
PDF is available here.
PDF is available here.
Abstract
Bacterial infection shortly after mating interferes with establishment of pregnancy. Injection of peptidoglycan-polysaccharide (PG-PS), a component of gram-positive bacteria, into sheep on day 5 after mating reduces pregnancy rate. Experiments were designed to evaluate the acute-phase response (APR)...
|
PMID: 20603027
PDF is available here.
PDF is available here.
Abstract
We diagnosed the patient with monoclonal immunoglobulin deposition disease (MIDD) associated with monoclonal IgA (mIgA). After the initiation of a monthly treatment with melphalan and predonisolone (MP therapy), the patient's serum IgA levels declined, and clinical remission was ultimately achieved....
|
PMID: 20454825
PDF is available here.
PDF is available here.
Marine Biotechnology (12)4 2010
Abstract
We found that the mechanisms of the inhibition may be that the beta-1,3-glucanase competed for binding to beta-1,3-glucan on the sensitive yeast cell wall with the WC91-2 toxin, causing decrease in the amount of the WC91-2 toxin bound to beta-1,3-glucan on the sensitive yeast cell wall and the activ...
|
PMID: 19941023
PDF is available here.
PDF is available here.
Clinical Immunology (136)2 2010
Abstract
We investigated the effects and mechanisms by which FTY720 (FTY) inhibits arthritis development in the SKG mouse rheumatoid arthritis (RA) model. FTY (1mg/kg/day) administration suppressed the progression of laminarin-induced arthritis in SKG mice. FTY treatment decreased IL-6 and TNF-alpha expressi...
|
PMID: 20421177
PDF is available here.
PDF is available here.
Abstract
In the present work, a new particulate controlled release system was prepared, by coating alginate-g-PCL/Ca(2+) beads with chitosan. The swelling behaviour and controlled release of a poorly water-soluble drug (theophylline) model were studied in media of varying pH, by simulating human fluids at 37...
|
PMID: 20471413
PDF is available here.
PDF is available here.
Abstract
These results indicated that EP and PF possessed synergistically immune enhancement, EP-PF had the best efficacy, especially at medium dose, and would be expected to exploit into a new-type immunopotentiator.
Copyright 2010 Elsevier B.V. All rights reserved....
|
PMID: 20562020
PDF is available here.
PDF is available here.
Abstract
In this paper, the crude polysaccharides from the flowers of tea plant (Camellia sinensis) (TFPS) extracted with hot water were fractionated on a DEAE Sepharose FF chromatography to get TFPS1 with a yield of 18%. The properties and chemical compositions of TFPS1 were analyzed with GC, HPGPC, IC, IR...
|
PMID: 20430052
PDF is available here.
PDF is available here.
Abstract
The extraction conditions of intracellular polysaccharide (IPS) from Pleurotus sp. mycelium in submerged culture were investigated. Four parameters affecting the IPS extraction, ultrasonic treatment time, extraction temperature, extraction time and ethanol concentration, were determined by single fa...
|
PMID: 20580645
PDF is available here.
PDF is available here.
Abstract
Agaricus blazei polysaccharides were analyzed by GC-MS. Results indicated that the polysaccharides contained glucose (93.87%), mannose (3.54%), and arabinose (2.25%). The compositional analysis was completed by the methylation data. These data indicated that Agaricus blazei polysaccharides are gluca...
|
PMID: 20471414
PDF is available here.
PDF is available here.
Abstract
We suggest that the molecular morphology of TPS is a homogeneous and spherical polymer with branch in solution.
Copyright 2010 Elsevier B.V. All rights reserved....
|
PMID: 20438749
PDF is available here.
PDF is available here.
GC-MS, FT-IR analysis of black fungus polysaccharides and its inhibition against skin aging in mice.
Abstract
The monosaccharide compositions, molecular weights, structure were investigated for the black fungus polysaccharides. Analysis of sugar components by gas chromatograph-mass spectrometer (GC-MS) showed that component ratios of neutral sugars in the polysaccharides were Glc:Man=82.97:12.93. Fourier tr...
|
PMID: 20371369
PDF is available here.
PDF is available here.
Abstract
In this study, structural features of Tricholoma matsutake polysaccharide (TMP-A) were investigated by a combination of infrared (IR) spectra, gas chromatography-mass spectrometry (GC-MS), nuclear magnetic resonance (NMR) spectroscopy. The results indicated that TMP-A had a backbone of 1,4-beta-d-gl...
|
PMID: 20430053
PDF is available here.
PDF is available here.
Thrombosis and Haemostasis (104)2 2010
Abstract
Fondaparinux is a synthetic antithrombotic agent with specific anti-factor Xa activity. A population pharmacokinetic model of fondaparinux, based on data obtained in patients included in phase II/III trials, has been described. However, the validity of this model in everyday practice needed to be con...
|
PMID: 20539905
PDF is available here.
PDF is available here.
Abstract
When injected into adult or nymphal Locusta that have been deprived of food for 2h, immunogens such as laminarin and bacterial LPS can induce an almost immediate dose-dependent state of anorexia for at least 1h. Such anorexia is a component of a medley of physiological and behavioural changes called...
|
PMID: 20416315
PDF is available here.
PDF is available here.
Journal of Medical Microbiology (59)Pt 8 2010
Abstract
We have shown that chicken (but not human) intestinal mucus inhibits C. jejuni internalization. In this study, we test the hypothesis that chicken mucin, the main component of mucus, is responsible for this inhibition of C. jejuni virulence. Purified chicken intestinal mucin attenuated C. jejuni bin...
|
PMID: 20466838
PDF is available here.
PDF is available here.
Abstract
Production of IL-8 by Ca9-22 cells was significantly increased when the cells were treated with OxLDL, but not with native LDL or acetylated LDL. Production of PGE(2) by Ca9-22 cells was enhanced by co-incubation with OxLDL and interleukin-1 beta (IL-1 beta). Scavenger receptor inhibitors, fucoidan...
|
PMID: 20412422
PDF is available here.
PDF is available here.
Abstract
Collectively, the results reveal certain novel effects of PSP in lymphocyte homoeostasis and suggest potential as a specific immunomodulatory adjuvant for clinical applications in the treatment of autoimmune diseases....
|
PMID: 20663037
PDF is available here.
PDF is available here.