Abstract
These results indicate a critical role for TLR4 in impairing renal function during ovine endotoxemia that is independent of changes in central hemodynamics....
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PMID: 21394006
PDF is available here.
Abstract
These results indicate a critical role for TLR4 in impairing renal function during ovine endotoxemia that is independent of changes in central hemodynamics....
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PMID: 21394006
PDF is available here.
Abstract
I or II parturients were randomly allocated to three groups: group 10RL, 15RL and 20RL to receive 10, 15 and 20 mL/kg of Ringer's lactate (RL) respectively within 15 minutes (min) before the spinal block. Spinal anesthesia was performed with hyperbaric bupivacaine 12 mg, morphine 100 microg and fent...
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PMID: 21612139
PDF is available here.
Abstract
Our objective was to compare the effects of continuing or withholding furosemide on the day of noncardiac elective surgery on intraoperative hypotension among chronic users of furosemide.
A double blind, randomized, placebo controlled trial was conducted at 3 North American university centers betwee...
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PMID: 21035594
PDF is available here.
Abstract
This study evaluated the effect of 17β-estradiol (E2) administration on cardiovascular parameters in male rats after trauma-hemorrhage and for an extended period (3 hours) of severe hypotension, based on blood-pool single photon emission computed tomography imaging.
After a 5-cm midline laparotomy,...
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PMID: 20571453
PDF is available here.
Abstract
Despite intensive therapy, refractory pediatric septic shock has a high rate of morbidity and mortality. Additional treatments are needed to improve outcomes in such cases.
To report the clinical effects of continuous terlipressin infusion as rescue treatment for children with septic shock refractor...
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PMID: 20841511
PDF is available here.
Abstract
We investigated the role of PPARδ in the modulation of the nuclear factor-κB (NF-κB)-driven inflammatory response to polymicrobial sepsis in vivo and in macrophages in vitro. We demonstrated that administration of GW0742, a specific PPARδ ligand, provided beneficial effects to rats subjected to...
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PMID: 20709805
PDF is available here.
Abstract
We describe a 15-year-old adolescent girl who experienced continued delirium 5 days after an overdose of quetiapine, trazodone, and clonidine. The patient initially presented with sedation and stable vital signs. After 3 days of gradual improvement, she experienced episodes of delirium coinciding wi...
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PMID: 20930599
PDF is available here.
Abstract
The objective of this study was to describe the pattern of pediatric carvedilol ingestions reported to poison centers.
Cases were all carvedilol ingestions by patients aged 0 to 5 years reported to Texas poison centers during 2000 to 2008. Multiple substance ingestions and patients not followed up t...
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PMID: 20881906
PDF is available here.
Abstract
We report literature management of such infection. Although pyometra is an uncommon disease, it should be kept in mind as delayed management may lead to fatal outcome....
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PMID: 20926206
PDF is available here.
Abstract
We hypothesized that the systolic blood pressure associated with increased mortality resulting from hemorrhagic shock increases with increasing age. The Los Angeles County Trauma Database was queried for all moderate to severely injured patients without major head injuries admitted between 1998 and...
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PMID: 21105603
PDF is available here.
Abstract
A preoperative increase in blood pressure after position change may be a good variable to predict hypotension during spinal anesthesia for cesarean delivery....
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PMID: 20686012
PDF is available here.
Abstract
We describe a very simple and innovative technique of using the arterial line for reliable recording of arterial oxygen saturation (SpO(2)) in such patients. We conclude that the arterial line can be used as an extension of the artery and SpO(2) may be reliably measured using the arterial line in su...
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PMID: 20635123
PDF is available here.
Abstract
Anaphylaxis is a serious, systemic allergic reaction that is rapid in onset and can cause death. Anaphylaxis often occurs in the absence of a health care professional, so it is essential for patients at risk for anaphylaxis to be identified and prepared in the event of an emergency. Identifying at-r...
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PMID: 20714449
PDF is available here.
Shufeng Chen,
Hongwei Wang,
Xiangfeng Lu,
De-Pei Liu,
Jing Chen,
Cashell E Jaquish,
Dabeeru C Rao,
James E Hixson,
Tanika N Kelly,
Liping Hou,
Laiyuan Wang,
Jianfeng Huang,
Chung-Shiuan Chen,
Treva K Rice,
Paul K Whelton,
Jiang He,
Dongfeng Gu and
GenSalt Collaborative Research Group
Abstract
A large proportion of the phenotypic variation in blood pressure (BP) appears to be inherited as a polygenic trait. This study examined the association between 12 single nucleotide polymorphisms (SNPs) in the guanine nucleotide binding protein beta polypeptide 3 (GNB3) and adducin 1 alpha (ADD1) gen...
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PMID: 20473689
PDF is available here.
Abstract
We recommend that a prospective national SAMM audit process be introduced in New Zealand as a quality of care measure....
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PMID: 20716262
PDF is available here.
Yaz Y Kisanuki,
Noriaki Emoto,
Takashi Ohuchi,
Bambang Widyantoro,
Keiko Yagi,
Kazuhiko Nakayama,
Rafal M Kedzierski,
Robert E Hammer,
Hiromi Yanagisawa,
S Clay Williams,
James A Richardson,
Takashi Suzuki and
Masashi Yanagisawa
Abstract
We generated a mouse strain (ET-1(flox/flox);Tie2-Cre mice) in which ET-1 is disrupted specifically in endothelial cells. ET-1 peptide levels in plasma, heart, lung, kidney, and brain homogenates were reduced by 65% to 80% in these mice. mRNA levels for ET receptors were unaltered except that the ET...
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PMID: 20516397
PDF is available here.
Abstract
We report our experience with four patients with spinal cord injury in a pilot project, presenting for laparoscopic insertion of diaphragmatic phrenic nerve pacing leads inserted. The surgery took about two hours and diaphragmatic mapping precluded muscle relaxants. We used desflurane with remifenta...
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PMID: 20715740
PDF is available here.
Abstract
Preload with crystalloid or colloid solution is widely recommended for the prevention of maternal hypotension during spinal anaesthesia. A combination of simultaneous rapid crystalloid infusion with vasopressor has also been suggested. This study tested the hypothesis that ephedrine infusion with cr...
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PMID: 20715726
PDF is available here.
Abstract
We concluded that this coronary anomaly was an important contributory factor in our patient's prolonged unstable condition. This emphasizes the critical role of normal RCA flow under acute haemodynamic stress. Evaluation of the condition of RV perfusion and RCA patency might be justified in any prol...
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PMID: 20648453
PDF is available here.
Abstract
Babies are frequently exposed to cerebral hypoxia and ischemia (H/I) during the perinatal period as a result of stroke, problems with delivery, or postdelivery respiratory management. The sole approved treatment for acute stroke is tissue type plasminogen activator. H/I impairs pial artery dilation...
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PMID: 20435843
PDF is available here.
Abstract
A single bout of exercise can lead to a postexercise decrease in blood pressure in hypertensive individuals, called postexercise hypotension. Compelling evidence suggests that the central baroreflex pathway plays a crucial role in the development of postexercise hypotension. This review focuses on t...
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PMID: 20577060
PDF is available here.
Abstract
Hypotension and hypoxemia on admission were inadequate markers of extracranial injuries; incorporating more comprehensive extracranial injury assessment by the Injury Severity Score to the standard neurologic prognostic factors improved the accuracy of predictions on mortality after neurotrauma....
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PMID: 20526198
PDF is available here.
Abstract
High preoperative serum creatinine, low intraoperative urine output, and intraoperative hypotension contribute to the development of AKI, and intraoperative use of noradrenaline serves as a protective factor. The predictive model could potentially facilitate early prediction and surveillance of AKI....
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PMID: 20525552
PDF is available here.
Abstract
We describe a patient who received an inadvertent bolus of noradrenaline and developed significant haemodynamic instability associated with electrocardiographic and cardiac biomarkers indicative of diffuse myocardial injury and echocardiography findings of an "inverted" TTC. The patient made a full...
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PMID: 20513218
PDF is available here.
Abstract
Agreement between the direct and indirect BP measurements was determined by the Bland-Altman method. The SAP and MAP but not DAP bias varied significantly between each BP state. Normotensive absolute biases (mean [SD]) for SAP, MAP, and DAP were -14.7 mm Hg (15.5 mm Hg), -16.4 mm Hg (12.1 mm Hg), an...
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PMID: 20636984
PDF is available here.
Abstract
Risk factors for hypotension include increased sympathetic tone, increasing age, obesity, higher blocks and higher birthweight, but not multiple gestation. Methods aimed at countering effects of aortocaval compression do not reliably prevent hypotension. Intravenous crystalloid prehydration has poor...
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PMID: 20173633
PDF is available here.
Abstract
The purpose of establishing the RheoNet registry was to evaluate the safety and efficacy of rheopheresis, a specific method of therapeutic apheresis used to treat microcirculatory disorders. Apheresis centers providing rheopheresis therapy and physicians caring for the underlying disease were asked...
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PMID: 20609179
PDF is available here.
Abstract
A 72-year-old woman presented with a decreased level of consciousness and hypotension. The initial electrocardiogram demonstrated atrial fibrillation with a wide QRS complex. Her medical history revealed that she had just been started on propafenone. A diagnosis of propafenone toxicity was made and...
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PMID: 20548984
PDF is available here.
Abstract
We experienced anesthesia of a patient with pheochromocytoma on chronic hemodialysis who developed severe hypotension resistant to vasopressors after induction of general anesthesia. She was presented for spine surgery for destructive arthropathy of the cervical spine. Doxazosin up to 0.5 mg x day(-...
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PMID: 20560377
PDF is available here.
Abstract
The incidence of hypotension was similar in the P and N groups. Same doses of ephedrine were required to treat hypotension in the two groups. CONCLUSION: Crystalloid preload combined with low-dose spinal anaesthesia do not reduce the incidence of hypotension nor its severity....
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PMID: 20803854
PDF is available here.
Abstract
In group A, a larger dose of ephedrine was needed (32 +/- 23 vs 19 +/- 16 mg; p = 0.004). Incidence of sensory block above T4 (52 vs 10%; p < 0.001), nausea (52 vs 22%; p = 0.005) and vomiting (25 vs 8%; p = 0.03) were all higher than in group B. Arterial hypotension was less frequent in group B (68...
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PMID: 20803855
PDF is available here.
Abstract
Discontinuation of AVP before NE may lead to a higher incidence of hypotension in patients recovering from septic shock receiving concomitant AVP and NE.
Copyright (c) 2010 Elsevier Inc. All rights reserved....
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PMID: 19926252
PDF is available here.
Abstract
This study showed that the use of an SCD could reduce the incidence of hypotension from 64% to 28% and supports hemodynamic variables such as mean arterial pressure and stroke volume index when patients were changed from the supine to the beach-chair position in those undergoing shoulder arthroscopy...
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PMID: 20511029
PDF is available here.
Abstract
Single, isolated hypotensive BP measurements during trauma resuscitations should not be ignored or dismissed. Instead, our results suggest that a single SBP reading <105 mm Hg is associated with severe injuries that often require immediate operative or endovascular treatment and surgical intensive c...
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PMID: 20539171
PDF is available here.
Abstract
Our findings suggest a limited brain exposure of the P-glycoprotein substrates 11, 12 and 21.
2010 Elsevier Ltd. All rights reserved....
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PMID: 20363132
PDF is available here.
Abstract
We did not use vasopressors to avoid the relapse of myocardial ischemia. The anesthetic course was uneventful thereafter. This cardiac event seemed to be derived from coronary spasm caused by acute sympathetic stimulation. The observations in this case suggest that the possibility of intraoperative...
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PMID: 20486583
PDF is available here.
Abstract
When anaesthetising patients for arthroscopic shoulder surgery, it is common practice to sit the patient in the beachchair position and to optimise arthroscopy by allowing relative hypotension. There is little published information regarding the cerebral haemodynamic effects of hypotension in the si...
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PMID: 20514957
PDF is available here.
Abstract
We studied the incidence of material hypotension with spinal bupivacaine or levobupivacaine (L-bupivacaine) and the spread after epidural saline injection.
After ethics committee approval, we randomized women scheduled for cesarean section to 4 groups to receive 5 mg of 0.25% bupivacaine with (n=51)...
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PMID: 20527340
PDF is available here.
Abstract
I or T, heart-type fatty acid-binding protein). These patients have an intermediate risk of an adverse outcome in the acute phase of PE. Existing data suggest that selected patients with intermediate-risk PE may benefit from early thrombolytic treatment, particularly if they have a low bleeding risk...
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PMID: 20216979
PDF is available here.
Abstract
This study found an association between cumulative duration of low BIS and mortality in the setting of cardiac surgery. Notably, this association was independent of both volatile anesthetic concentration and duration of anesthesia, suggesting that intermediate-term mortality after cardiac surgery wa...
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PMID: 20418692
PDF is available here.
Abstract
The images of Olympic athlete Nodar Kumaritasvili flying off his luge and contacting a fixed steel beam at the recent Winter Olympics in Vancouver, British Columbia, were shocking. But the resultant injuries and death of the young athlete were not surprising to EMS personnel who witnessed the incide...
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PMID: 20399377
PDF is available here.
Abstract
Calcium channel blocker (CCB) overdose is associated with dysrhythmias and atrioventricular (AV) block, however, experience with infant CCB overdose is limited. A 9-month-old girl was found playing with tablets of extended-release diltiazem 120 mg. The patient had two episodes of emesis, which conta...
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PMID: 18403171
PDF is available here.
Abstract
We therefore sought to examine the effect of hydrocortisone on early developmental outcome in premature newborns. We retrospectively examined the effect of hydrocortisone on developmental outcome during the first 2 years of life in premature infants <29 weeks' gestation at birth. Even though hydroco...
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PMID: 20139411
PDF is available here.
Abstract
In elderly patients undergoing dobutamine stress echocardiography, adopting the early atropine protocol offers a shorter test duration and a lower dobutamine dose, with consequently fewer adverse effects....
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PMID: 20425703
PDF is available here.