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Cell Physiological Phenomena (11)
Articles on Cell Physiological Phenomena
Global genomic characterization of acute lymphoblastic leukemia.
We are currently witnessing the rapid evolution and convergence of multiple genome-wide platforms that are making this goal a reality. Leading this effort are studies of the molecular lesions that underlie pediatric acute lymphoblastic leukemia (ALL). The recent application of microarray-based analy...
[The cell theory. Progress in studies on cell-cell communications].
Current data confirm the fundamental statement of the cell theory concerning the cell reproduction in a series of generations (omnis cellula e cellula). Cell communities or ensembles integrated by the signaling systems established in prokaryotes and protists and functioning in multicellular organism...
Biochemical insights into the mechanisms central to the response of mammalian cells to cold stress and subsequent rewarming.
Quantitative approaches to defining normal and aberrant protein homeostasis.
We discuss here an approach in which physico-chemical properties of proteins and their environments are used to understand the underlying principles governing this process, which is crucial in all living systems. By adopting the strategy of characterising the origins of specific diseases to inform u...
[APRIL, the spring of plasmacytes].
An advanced application of protein microarrays: cell-based assays for functional genomics.
We have implemented the technology by means of viral immobilization (2) on a novel surface of cluster-assembled nanostructured TiO2 (3) previously functionalized with an array of a docking protein. In this work, we present the detailed development of the "reverse infection cell-microarray based tech...
Integrated microscopy for real-time imaging of mechanotransduction studies in live cells.
Mechanical force is an important stimulus and determinant of many vascular smooth muscle cell functions including contraction, proliferation, migration, and cell attachment. Transmission of force from outside the cell through focal adhesions controls the dynamics of these adhesion sites and initiate...
Nanomaterial cell interactions: how do carbon nanotubes affect cell physiology?
Designer protein-based scaffolds for neural tissue engineering.
We present the development of a family of biomimetic scaffolds composed of chemically crosslinked, elastin-like proteins designed to support neural regeneration through a combination of cell adhesion and cell-induced degradation and remodeling. Through use of a modular protein-design strategy, a ran...