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Antibody-Producing Cells (1)
Articles on Antibody-Producing Cells
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Use of a weighted, automated analysis of the differential blood count to differentiate sepsis from non-infectious systemic inflammation: the...
Inflammation & Allergy Drug Targets 11(2):109-15 (2012) PMID 22280231
Rapid and accurate diagnosis and immediate treatment of sepsis are of crucial importance. However, differentiating sepsis from Systemic Inflammatory Response Syndrome (SIRS) is a difficult challenge. Many diagnostic approaches based on clinical chemistry surrogate markers have not improved the situat... -
Antibodies and ABO-incompatibility in pediatric transplantation.
Pediatr Transplant 15(8):778-83 (2011) PMID 22111997
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Supplemental β-carotene increases IgA-secreting cells in mammary gland and IgA transfer from milk to neonatal mice.
Br J Nutr 105(1):24-30 (2011) PMID 20727240
We investigated the effect of supplemental β-carotene for maternal mice during pregnancy and lactation on IgA antibody-secreting cells (ASC) in mammary gland and guts and on IgA transfer from milk to neonatal mice. Pregnant mice were fed untreated or 50 mg/kg β-carotene-supplemented diets from 6... -
Homeostatic expansion of autoreactive immunoglobulin-secreting cells in the Rag2 mouse model of Omenn syndrome.
J Exp Med 207(7):1525-40 (2010) PMID 20547828 PMCID PMC2901059
We report the detection of plasma cells in lymphoid organs of OS patients, in which circulating B cells are undetectable. Hypomorphic Rag2(R229Q) knock-in mice, which recapitulate OS, revealed, beyond severe B cell developmental arrest, a normal or even enlarged compartment of immunoglobulin-secreti... -
Expansion of immunoglobulin-secreting cells and defects in B cell tolerance in Rag-dependent immunodeficiency.
J Exp Med 207(7):1541-54 (2010) PMID 20547827 PMCID PMC2901061
We have studied a mut/mut mouse model of leaky SCID with a homozygous Rag1 S723C mutation that impairs, but does not abrogate, V(D)J recombination activity. In spite of a severe block at the pro-B cell stage and profound B cell lymphopenia, significant serum levels of immunoglobulin (Ig) G, IgM, IgA... -
An oral versus intranasal prime/boost regimen using attenuated human rotavirus or VP2 and VP6 virus-like particles with immunostimulating co...
Audio, Transactions of the IRE Professiona... 17(3):420-8 (2010) PMID 20107005
We determined the impact of mucosal prime/boost regimens and vaccine type (attenuated Wa human rotavirus [AttHRV] or nonreplicating Wa 2/6 rotavirus-like particles [VLP]) on protection and antibody-secreting cell (ASC) responses to HRV in a neonatal gnotobiotic pig disease model. Comparisons of deli... -
Decreased CD4+CD25+ cells and increased dimeric IgA-producing cells in tonsils in IgA nephropathy.
J Nephrol 23(2):202-9 (2010) PMID 20213609
The relationship between tonsillar autoimmune response and the pathogenesis of IgA nephropathy (IgAN) has been previously demonstrated. However, the role of CD4+CD25+ cells, which play critical roles in maintaining peripheral tolerance and preventing autoimmunity, has not yet been de... -
Development of prophylactic recombinant HPV58-attenuated Shigella live vector vaccine and evaluation of its protective efficacy and immunoge...
Acta Biochim Biophys Sin (Shanghai) 41(2):137-45 (2009) PMID 19204831
To develop a prophylactic recombinant HPV58L1-attenuated Shigella live vector vaccine and evaluate its protective efficacy and immunogenicity in the guinea pig keratoconjunctivitis model, the HPV58L1 gene was cloned into vector pUCmt, and then subcloned into the suicide vector pCVD442. The recombina... -
Alpha1- and beta-adrenoblockers effects on immunogenesis in rats under thermoneutral conditions and after cooling of various extent.
Bull Exp Biol Med 147(2):208-12 (2009) PMID 19513423
Experiments with rats showed that ionophoretic delivery of alpha1-adrenoblocker into the skin does not change effects of superficial and deep cooling and did not affect the amount of the antibody producing cells in spleen and a blood level of circulating antibodies under thermoneutral conditions. Me... -
[Involvement of presynaptic 5-HT1A receptors in immunomodulation under conditions of psychoemotional state].
Zh Vyssh Nerv Deiat Im I P Pavlova 59(2):206-12 (2009) PMID 19445389
The development of the immune reaction after the activation or blockade of presynaptic 5-HT1A receptors, respectively, with a selective agonist or antagonist depends on specific behavioral patterns. Agonist of 5-HT1A receptors 8-OH-DPAT (0.1 mg/kg 15 min prior to immunization) did not change the num...