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Giant Cells, Foreign-Body (0):
Recent article
Giant Cells, Foreign-Body
Journal of Royal Society Interface (7)Suppl_5 2010
Abstract
We review the performance of the biomimetic coating both in vitro and in vivo....
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PMID: 20484228
PDF is available here.
PDF is available here.
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Journal of Royal Society Interface (7)Suppl_5 2010
Abstract
We review the performance of the biomimetic coating both in vitro and in vivo....
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PMID: 20484228
PDF is available here.
PDF is available here.
Abstract
We investigated whether there were differences in immunologic hypersensitivity reactions in retrievals from revised THAs with ceramic-on-polyethylene versus metal-on-metal bearing couples.
We compared newly formed capsule and periprosthetic interface membranes from revision surgery f...
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PMID: 20020335
PDF is available here.
PDF is available here.
Abstract
Scanning electron microscopy analyses of the barrier revealed a microstructure resembling cancellous bone. Interconnecting pores and channels, measuring between 6 and 60 microm in diameter, formed by smooth internal walls were observed throughout the device. Two distinct patterns of porosity were ob...
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PMID: 20380512
PDF is available here.
PDF is available here.
Abstract
Archives of Surgery (145)5 2010
Abstract
Forensic Science International (197)1-3 2010
Abstract
We report the case of a 32-year old man, dying suddenly and unexpectedly after a well-known history of drug abuse for more than a decade. The granulomas are caused by foreign particle embolization immediately after intravenous injection of not only the drug itself but also of adulterants, e.g. cotto...
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PMID: 20137873
PDF is available here.
PDF is available here.
Abstract
The patient was a man who had suffered from repeated pneumothoraces since August 2003, when he was 16 years old. A right pneumothorax was observed at age 21 years, in April 2008. At the same time, a dry cough began to appear and diffuse small nodular shadows in both lung fields were found on a chest...
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PMID: 20432968
PDF is available here.
PDF is available here.
Abstract
We investigated whether concurrent exposure of macrophages to phagocytic and fusogenic stimuli would limit fusion. Induction of phagocytosis by addition of 3.0 mum-diameter polystyrene microspheres to cells under fusogenic conditions, at ratios of 1:10, 1:1, and 10:1 did not prevent fusion. To deter...
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PMID: 19536825
PDF is available here.
PDF is available here.
Clinical Imaging (34)5 2010
Abstract
We consider the higher the metabolic activity of a lesion, the less likely of malignant if it was stable in size over time....
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PMID: 20813307
PDF is available here.
PDF is available here.
Abstract
These results suggest that lymphocytes prefer interactions with adherent macrophages and FBGCs, resulting in lymphocyte activation, and these interactions can be influenced by biomaterial surface chemistries....
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PMID: 19148923
PDF is available here.
PDF is available here.
Abstract
We report the case of an oil industry worker diagnosed with hard metal lung disease. The diagnosis was based on the clinical, radiological and anatomopathological analysis, as well as on pulmonary function testing....
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PMID: 20126930
PDF is available here.
PDF is available here.
Abstract
Lymphocytes have been shown to be involved in modulating monocyte and macrophage behavior in the foreign body reaction. Lymphocyte effects on biomaterial-adherent macrophage and foreign body giant cell (FBGC) behavior were further investigated by culturing monocytes alone or together with lymphocyte...
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PMID: 18437695
PDF is available here.
PDF is available here.
Abstract
A 60-year-old lady with mild fever, blood tinged sputum, and a left upper lung mass had whole body F-18 2-deoxy-D-glucose (FDG) positron emission tomography (PET)-computer tomography (CT) for cancer staging. The PET-CT imaging revealed FDG accumulation in the left upper lung lesion. The histopatholo...
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PMID: 19300059
PDF is available here.
PDF is available here.
Biomaterials (30)5 2009
Abstract
We hypothesized that cmvIL-10 downmodulates the FBR, impairing degradation of biomaterial. We studied the effect of cmvIL-10 on the FBR to subcutaneously implanted hexamethylenediisocyanate-crosslinked dermal sheep collagen (HDSC) discs in rats. CmvIL-10 impaired macrophage influx, vascularization a...
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PMID: 19038442
PDF is available here.
PDF is available here.
Dermatologic Surgery (35 Suppl 1) 2009
Abstract
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie (50)4 2009
Abstract
We present the case of a 23-year-old female patient with multiple surgical interventions during the last year, for iterative ileal spontaneous perforation with generalized peritonitis of which cause was initially assigned to intestinal tuberculosis. Actual episode of generalized peritonitis was dete...
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PMID: 19942978
PDF is available here.
PDF is available here.
Abstract
We report a case of huge CG extending to the middle cranial fossa. Temporal bone computerized tomography showed a soft tissue mass which destroyed the bony plate of the posterior and middle cranial fossa. On magnetic resonance imaging, the mass revealed a high signal on both T1 and T2-weighted image...
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PMID: 19368149
PDF is available here.
PDF is available here.
Abstract
We present the case of a patient who underwent surgery for a probable Klastkin tumor. During the intervention, a 1.5-cm tumor, with firm consistency, extrinsic to the biliary tract was found; the mass was extirpated with no compromise to the biliary tract. Macroscopic examination revealed suture (si...
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PMID: 19174097
PDF is available here.
PDF is available here.
Abstract
Recent studies involving mainly osteoclasts and foreign body giant cells have revealed a number of common factors, for example, vitronectin, an adhesion protein, dendritic cell-specific transmembrane protein, a fusion factor, and macrophage fusion receptor, that contribute to giant cell formation an...
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PMID: 19057205
PDF is available here.
PDF is available here.
Clinical Toxicology (46)9 2008
Abstract
We report two cases of multiorgan dysfunction following silicone injection. CASE REPORT: Two transsexual males presented to the emergency department with altered consciousness after receiving subcutaneous injections of silicone into the hip and buttocks. Each patient had received injections totaling...
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PMID: 18608261
PDF is available here.
PDF is available here.
Abstract
We present a case of a witnessed sudden death of a 27-year-old adult man with no antecedent trauma who subsequently was found to have a previously undiagnosed Chiari I malformation. Cases of sudden unprovoked respiratory collapse in children and adults with Chiari I malformation have been well docum...
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PMID: 18725782
PDF is available here.
PDF is available here.
Tijdschrift voor diergeneeskunde (133)16 2008
Abstract
Equine sarcoidosis is a rare disorder usually characterized by exfoliative dermatitis, moderate to severe wasting, and sarcoidal granulomatous inflammation of multiple organ systems. It has an unknown aetiopathogenesis. The condition is not related to equine sarcoid. This case report describes gener...
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PMID: 18788186
PDF is available here.
PDF is available here.
Abstract
Novel self-assembled monolayers (SAMs) designed to present homogenous surface chemistries were utilized to further investigate the material surface chemistry dependent macrophage and foreign-body giant cell (FBGC) behaviors, including macrophage adhesion, fusion, and apoptosis. Contact angle analysi...
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PMID: 18412136
PDF is available here.
PDF is available here.
Abstract
A 39-year-old woman is described in whom histopathologic examination of a nodule of the cheek mucosa was suggestive of a mucoepidermoid carcinoma. Only after the availability of a wider surgical specimen was a distinct foreign body reaction to polyacrylamide soft tissue filler observed. On inquiry,...
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PMID: 18313268
PDF is available here.
PDF is available here.
Dermatologic Surgery (34 Suppl 1)s1 2008
Abstract
BACKGROUND Polyacrylamide hydrogel (PAAG) is a nondegradable water-based polymer with high viscoelasticity. The gel is used as a tissue filler, the only risk being prolonged infection with anaerobic, contaminating microorganisms if not treated early with broad-spectrum antibiotics. OBJECTIVE With si...
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PMID: 18547185
PDF is available here.
PDF is available here.
Abstract
Seminars in Immunology (20)2 2008
Abstract
Our perspective has been on the inflammatory and wound healing response to implanted materials, devices, and tissue-engineered constructs. The incorporation of biological components of allogeneic or xenogeneic origin as well as stem cells into tissue-engineered or regenerative approaches opens up a...
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PMID: 18162407
PDF is available here.
PDF is available here.
Abstract
We hypothesized that the cells neighboring the PLGA implant might have an inflammatory response that could be reduced by impregnating demineralized bone particles (DBPs) into the PLGA. We manufactured five different ratios of DBP/PLGA hybrid materials, with each material containing 0, 10, 20, 40, an...
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PMID: 18352826
PDF is available here.
PDF is available here.
Der Orthopäde (37)2 2008
Abstract
We report about a patient who developed recurrent effusion and granulomatous synovitis following total knee arthroplasty in association with latex allergy....
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PMID: 18210090
PDF is available here.
PDF is available here.
Abstract
We investigate the participation of protein kinase C (PKC) in the interleukin (IL)-4-induced fusion of human monocyte-derived macrophages and foreign body giant cell (FBGC) formation in vitro. The PKC inhibitors H-7 and calphostin C attenuated macrophage fusion, whereas H-8, which is more selective...
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PMID: 18067888
PDF is available here.
PDF is available here.
Abstract
We seeded human bone marrow cells on uncoated ultrasmooth polished TiAl6V4 samples as well as on coated TiAl6V4 discs of the same diameter with two different calcium phosphates coatings, monetite (DCP) and hydroxyapatite (OHAp), both with rougher surfaces. On uncoated ultrasmooth polished TiAl6V4 di...
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PMID: 18503127
PDF is available here.
PDF is available here.
Histopathology (52)2 2008
Abstract
Abstract
Spongostan, a gelatinous haemostatic sponge, is used in surgery. Moreover, Spongostan may serve as a scaffold for proteins or cells implanted into defects. At the site of biomaterial implantation, foreign body giant cells (FBGCs) may develop which are responsible for Spongostan degradation. The purp...
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PMID: 18468404
PDF is available here.
PDF is available here.
Abstract
Surgical procedure provoked intestinal dilation, as well as segmented chambers along the descending colon. Retained fecalomas between the valves and proximal to them were also noted. Six rats died of intestinal obstruction due to fecal impaction at the surgical site. The sequence of events was: stas...
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PMID: 18552992
PDF is available here.
PDF is available here.
Brazilian Dental Journal (19)1 2008
Abstract
This study performed a histological analysis of the effect of formocresol associated to endotoxin (LPS) in the subcutaneous connective tissue of mice. Ninety mice were randomly assigned to 3 groups (n=30). Each animal received one plastic tube implant containing endotoxin solution (10 mg/mL), formoc...
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PMID: 18438558
PDF is available here.
PDF is available here.
Abstract
A 69-year-old man with a 0.6 cm yellowish polypoid lesion in the lateral soft palate for 2 years is presented. Histological examination of the tumor revealed a small, well-differentiated, mucoepidermoid carcinoma dominated by densely packed cholesterol clefts in association with an exuberant foreign...
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PMID: 18538486
PDF is available here.
PDF is available here.
Abstract
Hard metal disease (HMD), the interstitial lung disease caused by dusts in the cemented tungsten carbide (WC) industry, has been attributed to cobalt. The rare histologic pattern of giant cell interstitial pneumonia (GIP) is characteristic in HMD. The authors reviewed the history of HMD and 100 case...
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PMID: 18628077
PDF is available here.
PDF is available here.
Biomaterials (28)34 2007
Abstract
To better understand the relationship between macrophage/foreign body giant cell adhesion and activation on surface-modified biomaterials, quantitative assessment of adherent cell density (cells per mm(2)) and cytokine production (pgs per mL) were determined by ELISA. Further analysis to identify ce...
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PMID: 17706278
PDF is available here.
PDF is available here.
Abstract
Revision silicone arthroplasty provides excellent pain relief, and the majority of patients were pleased with their results. Objective results, however, were generally poor. Soft tissue reconstruction is more difficult to achieve than the primary procedure, as evidenced by minimal improvement in uln...
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PMID: 18070636
PDF is available here.
PDF is available here.
Abstract
We show that the gene expression of PMN chemoattractants, CXCL1/KC and CXCL2/MIP-2, is high in GCs micro-dissected from explanted Dacron, cross-linked collagen (HDSC), and bioactive ureido-pyrimidinone functionalized oligocaprolactone (bioactive PCLdiUPy). Conversely, the gene expression levels of T...
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PMID: 17567860
PDF is available here.
PDF is available here.
Biomaterials (28)33 2007
Abstract
In bone a role of connexin 43 has been implicated with the fusion of mononuclear precursors of the monocyte/macrophage lineage into multinucleated cells. In order to investigate the putative role of connexin 43 in formation of bone osteoclast-like foreign body giant cells which are formed in respons...
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PMID: 17719629
PDF is available here.
PDF is available here.
Movement Disorders (22)13 2007
Abstract
Mercury toxicity causes postural tremors, commonly referred to as "mercurial tremors," and cerebellar dysfunction. A 23-year woman, 2 years after injecting herself with elemental mercury developed disabling generalized myoclonus and ataxia. Electrophysiological studies confirmed the myoclonus was pr...
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PMID: 17708573
PDF is available here.
PDF is available here.
Abstract
Abstract
We used interleukin-4 to induce multinucleation of murine bone marrow-derived macrophages and observed changes in cell shape, including elongation and lamellipodia formation, before fusion. Because cytoskeletal rearrangements are regulated by small GTPases, we examined the effects of inhibitors of R...
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PMID: 17556592
PDF is available here.
PDF is available here.
Abstract
BACKGROUND: Dentists need to be aware of soft-tissue lesions resulting from cosmetic facial/lip procedures that involve the use of injectable materials. Common side effects detected on clinical examination may include edema, bruising and noninflammatory lip nodules. CASE DESCRIPTION: A 51-year-old w...
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PMID: 17670876
PDF is available here.
PDF is available here.
Abstract
The Arista-assisted microvascular anastomosis is an alternative to the conventional suture-only method because it reduces the anastomosis time significantly and does not cause narrowing of the vessel wall. We believe that this technique has the potential for improving the performance of microvascula...
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PMID: 17975772
PDF is available here.
PDF is available here.
Abstract
Macrophages may phagocytose inhaled tungsten via CD163 and play an important role in forming the fibrotic lesion of hard metal lung disease with cytotoxic T lymphocytes....
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PMID: 17363774
PDF is available here.
PDF is available here.
Abstract
Abstract
Autogenous malleus, incus, and cortical bone grafts behaved in a similar manner and maintained their morphological size, shape, and contour for extended periods of time, at least up to 30 years. These histopathologic observations support the continued use of autograft ossicular and cortical bone gra...
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PMID: 17419521
PDF is available here.
PDF is available here.
Abstract
We describe the case of a 45-year-old woman with a 2-week history of painful erythematous papules on the palmar aspect of the fingertips of her right hand, resulting from contact with a cholla cactus 3 weeks prior in Arizona. The patient initially was given clobetasol propionate ointment, resulting...
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PMID: 17674586
PDF is available here.
PDF is available here.
Respiratory Care (52)2 2007
Abstract
Abstract
Microsurgery is the procedure of choice for vascular anastamoses between 0.5 and 0.8 mm in diameter. The objective of this study was to compare two types of suture materials: non-absorbable, commonly used for vascular anastamoses in microsurgery, vs absorbable, rarely evaluated in this type of surge...
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PMID: 17330204
PDF is available here.
PDF is available here.
Abstract
We believe that this was caused by subclinical leakage of the implant contents through a degrading shell. The biodegradability of hydrogel makes it impossible to ascertain the precise nature of the material that leaked out. Given this demonstrable leakage, the adverse clinical effects and the potent...
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PMID: 17223521
PDF is available here.
PDF is available here.
Abstract
Abstract
We demonstrated in our study, in spite of using implants with high gel cohesiveness (fourth generation), the presence of vacuolated macrophages with microcystic structures containing silicone and silicone particles in the capsular tissue. Greater capsular thickness was associated with an increased n...
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PMID: 16991042
PDF is available here.
PDF is available here.
Rheumatology (45)7 2006
Abstract
Morphometric analysis revealed that the ADAM9+ area in the revision total hip replacement (THR) interface was larger than in primary THR samples (37.6+/-5.1 vs 5.2+/-0.8%, P=0.002). Double immunofluorescence staining showed that CD68+ interface tissue macrophages and multinuclear giant cells were AD...
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PMID: 16418197
PDF is available here.
PDF is available here.
Abstract
Frequency of histopathological membrane types was: type I 54.3%, type II 19.7%, type III 5.4%, type IV 15.4%, and not assessable 5.1%. The mean period between primary arthroplasty and revision surgery was 10.1 years for type I, 3.2 years for type II, 4.5 years for type III and 5.4 years for type IV....
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PMID: 16731601
PDF is available here.
PDF is available here.
Abstract
We examined the development of foreign body giant cells in intimate contact with porous membranes of poly L-lactic acid containing 7% of plasticizer triethylcitrate implanted in the backs of rats. The membranes were removed 2, 7, 14, 21, 28, 60, 90 and 180 days after implantation, along with a porti...
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PMID: 16688589
PDF is available here.
PDF is available here.