Abstract
Liver steatosis, also called non-alcoholic fatty liver, is characterized by a pathological fat accumulation in the liver, leading to liver damage in the form of inflammation and fibrosis. These histological features are similar to those in alcoholic hepatitis. Obesity is known to be...
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PMID: 21216209
PDF is available here.
Abstract
From the mid-1950s, it was observed that liver injury by a variety of toxins greatly sensitized the host to the effects of administered lipopolysaccharide. In the nutritional cirrhosis of choline deficiency, and in acute toxic injury as well, the need for the presence of enteric endotoxin was demons...
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PMID: 20890945
PDF is available here.
Abstract
We investigated the roles of a different class of proinflammatory cytokines, interleukin-4 (IL-4) and IL-13, in the induction of inflammatory tissue macrophage accumulation and/or hemophagocytosis. We found that large amounts of IL-4, but not IL-13, delivered via an implanted mini-pump or IL-4/anti-...
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PMID: 20570861
PDF is available here.
F Thomas Wunderlich,
Peter Ströhle,
A Christine Könner,
Sabine Gruber,
Sulay Tovar,
Hella S Brönneke,
Lisa Juntti-Berggren,
Luo-Sheng Li,
Nico van Rooijen,
Claude Libert,
Per-Olof Berggren and
Jens C Brüning
Abstract
We have generated mice with hepatocyte-specific IL-6 receptor (IL-6R) alpha deficiency (IL-6Ralpha(L-KO) mice). These animals showed no alterations in body weight and fat content but exhibited a reduction in insulin sensitivity and glucose tolerance. Impaired glucose metabolism originated from atten...
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PMID: 20816090
PDF is available here.
Abstract
CASP led to significant sinusoidal perfusion failure, increased leukocyte recruitment, hepatocellular apoptosis and increased levels of TNF, IL-6, and IL-10 in the liver and plasma. KC depletion before CASP significantly reduced leukocyte recruitment to the liver and hepatocellular apoptosis. IL-10...
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PMID: 20300005
PDF is available here.
Abstract
To explore the significance of the expression of carcinoembryonic antigen receptors (CEAR) in digestive organs.
Specimens were procured from 20 male BALB/c mice including esophagus, small intestine, stomach, colon, pancreas, and liver. Kupffer cells were obtained by d...
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PMID: 20737316
PDF is available here.
Abstract
These findings suggest that caffeine may represent a novel, protective strategy against alcoholic liver injury by attenuating oxidative stress and inflammatory response....
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PMID: 20221667
PDF is available here.
Abstract
It has been documented that chemokines can positively regulate liver regeneration at the tissue level after partial hepatectomy. However, the precise mechanism of the effects of chemokines on regeneration at the cellular level remains poorly defined. In this study, 8 cell types from rat regenerating...
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PMID: 20725148
PDF is available here.
Abstract
We demonstrate that gadolinium chloride (GdCl3) pretreatment inactivates RES macrophages, thereby increasing circulatory time and amplifying the tumor-specific signal of conjugated nanoparticles in vivo. The experimental results were validated using compartmental modeling, and the rate parameters fo...
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PMID: 20586481
PDF is available here.
Abstract
In Hfe(-/-) mice, transplantation of livers from Hfe(+/+) mice reversed the iron-loading phenotype associated with hemochromatosis (regardless of Hfe expression in intestine). However, KCs still had low levels of iron that were not affected by hepatic hepcidin expression. These findings indicate an...
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PMID: 20338170
PDF is available here.
Abstract
In a mouse model of NASH, TLR9 signaling induces production of IL-1beta by Kupffer cells, leading to steatosis, inflammation, and fibrosis.
Copyright 2010 AGA Institute. Published by Elsevier Inc. All rights reserved....
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PMID: 20347818
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Philipp A Lang,
Mike Recher,
Nadine Honke,
Stefanie Scheu,
Stephanie Borkens,
Nicole Gailus,
Caroline Krings,
Andreas Meryk,
Andreas Kulawik,
Luisa Cervantes-Barragan,
Nico Van Rooijen,
Ulrich Kalinke,
Burkhard Ludewig,
Hans Hengartner,
Nicola Harris,
Dieter Häussinger,
Pamela S Ohashi,
Rolf M Zinkernagel and
Karl S Lang
Abstract
We used the lymphocytic choriomeningitis virus model system to analyze the role of tissue macrophages/Kupffer cells in this process. Our findings demonstrated that Kupffer cells are essential for the efficient capture of infectious virus and for preventing viral replication. The latter process invol...
|
PMID: 20578253
PDF is available here.
Abstract
Amiloride lowers portal pressure in rat liver cirrhosis by inhibition of intrahepatic vasocontraction. Therefore, patients with cirrhosis and portal hypertension may benefit from amiloride therapy....
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PMID: 20551467
PDF is available here.
Abstract
We performed a kinetic study in mice with different sizes of PEG-coated AuNPs. Small AuNPs (4 or 13nm) showed high levels in blood for 24h and were cleared by 7days, whereas large (100nm) AuNPs were completely cleared by 24h. All AuNPs in blood re-increased at 3months, which correlated with organ le...
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PMID: 20193702
PDF is available here.
Abstract
2-Butoxyethanol increases hemangiosarcomas selectively in male mouse liver after chronic inhalation through mechanisms that have not fully been elucidated. Hemolysis, a primary toxic effect associated with 2-butoxyethanol exposure in rodents, increased hemosiderin (iron) deposition in Kupffer cells...
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PMID: 20153399
PDF is available here.