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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Connective Tissue Cells (9):
Recent article
Connective Tissue Cells
Abstract
We describe the efficient derivation of connective tissue progenitors (CTPs) from hESC lines and fetal tissues. The CTPs were significantly expanded and induced to generate tendon tissues in vitro, with ultrastructural characteristics and biomechanical properties typical of mature tendons. We descri...
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PMID: 20486794
PDF is available here.
PDF is available here.
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Abstract
We present a system that combines image segmentation and information visualization principles for an integrated analysis of fluorescence micrographs of tissue samples. The analysis aims at the detection and annotation of cells of the Islets of Langerhans and the whole pancreas, which is of great imp...
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PMID: 19969439
PDF is available here.
PDF is available here.
Abstract
In cases of intractable diarrhea in infancy, even without ocular symptoms, a systematic ophthalmologic examination should be performed. It also should be associated with the pathologic examination of both the conjunctival and the intestine mucosae, which helps to diagnose congenital tufting enteropa...
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PMID: 20447614
PDF is available here.
PDF is available here.
Abstract
The results show that gingival tissue cells fulfill the minimal criteria proposed by the International Society for Cellular Therapy to be defined as MSCs. Cell characterization was consistently positive for CD90, CD105, CD73, CD44, and CD13 markers and negative for hematopoietic markers CD34, CD38,...
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PMID: 20450355
PDF is available here.
PDF is available here.
Tissue & Cell (42)2 2010
Abstract
We previously reported that Tenomodulin (Tnmd) and Chondromodulin-1 (Chm1) are homologous angiogenesis inhibitors and predominantly expressed in the avascular region of tendons and cartilage, respectively. In this study, we analyzed the expression of Tnmd, Chm1, alpha 1 chain of the type I collagen...
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PMID: 20334886
PDF is available here.
PDF is available here.
Abstract
Our findings suggest that an acid-treated HA block could function as a better scaffold for the 3D high-density culture of human periosteal cells in vitro, and this cell-HA complex had significant osteogenic potential at the site of implantation in vivo. Compared with the cell-free HA block, our cell...
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PMID: 20192869
PDF is available here.
PDF is available here.
Abstract
We have demonstrated that AdipoR1 is highly expressed in rat adventitia and cultured adventitial fibroblasts by quantitative real-time PCR, Western blotting and immunofluorescent staining, whereas Adipo2 is low-expressed. The expression of AdipoR1 have been observed to decrease gradually in adventit...
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PMID: 19947943
PDF is available here.
PDF is available here.
Abstract
The proliferation rate was similar for cells from each of the four valves. After longer periods of culture (> 10 days), cells from each valve spontaneously formed several calcification nodules, the process being accelerated in the presence of osteogenic additives (to 4-7 days). Alkaline phosphatase...
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PMID: 19852147
PDF is available here.
PDF is available here.
Abstract
Porcine buccal mucosa has been extensively used as an in vitro model to study the permeability of various diffusants and to assess their potential to be delivered through the buccal route. The relative contribution of each component of the buccal mucosa on drug permeability was assessed in this stud...
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PMID: 18506782
PDF is available here.
PDF is available here.
Abstract
Epithelial cells abundantly expressed IL10 in patients. The expression of b-defensins was very variable in both sulcular and gingival epithelium. TUNEL positive cells were observed in patients and control specimens with dominance in control group. Gingival epithelium showed moderate expression of bF...
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PMID: 19773628
PDF is available here.
PDF is available here.
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie (50)4 2009
Abstract
We have not noticed any cells with myofibroblast morphology or immunophenotype. In Ta tumors, no matter the differentiation grade, we have not noticed myofibroblasts neither between the tumor cells nor at distance. The myofibroblasts were identified in seven of the 26 (26.92%) tumors in T1 stage. In...
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PMID: 19942959
PDF is available here.
PDF is available here.
Abstract
This review provides an analysis of current data on the tissue and cell components of the vaginal portion of the uterine cervix (ectocervix - EC) in human female and on their interrelations under normal conditions and in the development of some pathological processes. Detailed histological and immuno...
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PMID: 20210105
PDF is available here.
PDF is available here.
Abstract
Immunology (125)4 2008
Abstract
We recently found that Bcl-3 is up-regulated in T cells from mice where FADD function is blocked by a dominant negative transgene (FADD-DN). To understand the importance of this, we generated FADD-DN/bcl-3(-/-) mice. Here, we report that T cells from these mice show massive cell death and severely r...
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PMID: 19137648
PDF is available here.
PDF is available here.
Abstract
Osteoarthritis (OA) resulting from trauma, degenerative or age-related disease presents a major clinical challenge due to the limited repair capacity of articular cartilage. This poor self-repair capacity of osteochondral defects has resulted in the development of a wide variety of new treatment app...
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PMID: 18842397
PDF is available here.
PDF is available here.
Abstract
Connective tissue progenitors (CTPs) are defined as the heterogeneous set of stem and progenitor cells that reside in native tissues and are capable of proliferation and differentiation into one or more connective tissue phenotypes. CTPs play important roles in tissue formation, repair, and remodeli...
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PMID: 18464246
PDF is available here.
PDF is available here.
Abstract
We verified CD34 and CD117 receptor expression under light and fluorescence microscope and performed a routine and a CD34-immuno-electron microscopy. CD34-positive cells were seen in the entire human GI tract. In the muscularis propria, shared morphologies similar to the c-kit-positive cells, in the...
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PMID: 19145703
PDF is available here.
PDF is available here.
Abstract
We describe recent advances concerning immunological aspects in the pathogenesis of bleomycin-induced murine scleroderma, laying stress on the involvement of interleukin-13 (IL-13) and plasminogen activator inhibitor-1 (PAI-1)....
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PMID: 19697510
PDF is available here.
PDF is available here.
Abstract
Although the role of the primary cilium as a sensory organelle in epithelial cells has been elucidated significantly over the past decade, the function of primary cilia in connective tissue cells has been studied less extensively. Primary cilia have been implicated as mechanotransducers in connectiv...
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PMID: 18727071
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
We present the mechanisms underlying this finding. First, we demonstrate that wild-type mesenchymal cells migrate to CCL4 more efficiently in vitro than CCR5(-/-) cells. Wild-type mesenchymal cells were also 3.6 (1.85 to 5.85) times more efficient than CCR5(-/-) cells at migrating into the lung afte...
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PMID: 18535183
PDF is available here.
PDF is available here.
Implant Dentistry (17)2 2008
Abstract
Initially the experimental implants showed greater bone attachment along the collar. With time the bone heights along the control and experimental collars were equivalent. However, the controls had more soft tissue downgrowth, greater osteoclastic activity, and increased saucerization compared with...
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PMID: 18545054
PDF is available here.
PDF is available here.
Abstract
Bone resorption in C3H/HeJ mice in the fourth, seventh, and tenth injection groups was significantly less than that C3H/HeN mice (P < 0.05). The number of RANKL-positive cells in C3H/HeJ mice in the 10th injection group was significantly smaller than that in C3H/HeN mice (P < 0.05). The numbers of i...
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PMID: 18402604
PDF is available here.
PDF is available here.
Abstract
Immunohistochemistry is a powerful investigative tool that can provide researchers with important supplemental information to the routine morphological assessment of musculo-skeletal connective tissues in health and disease and also during tissue repair and regeneration. A wide variety of antibodies...
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PMID: 18442701
PDF is available here.
PDF is available here.
Abstract
The histopathological features of lesions resected from children with Proteus syndrome predominantly include hamartomatous mixed connective tissue lesions, benign neoplasms such as lipomata, and lymphatic-rich vascular malformations....
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PMID: 18205855
PDF is available here.
PDF is available here.
Biochemistry (New York) (73)5 2008
Abstract
Complete and incomplete transitions of epitheliocytes into cells of mesenchymal type, so-called epithelial-mesenchymal transitions (EMT), take place in many types of normal morphogenesis and in epithelial carcinogenesis. Connective tissue cells (fibroblasts) also undergo considerable morphological c...
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PMID: 18605977
PDF is available here.
PDF is available here.
Abstract
Our findings indicate that cross-talk among Smad, MAPK, and integrin signaling pathways may account mainly for the mechanism of AF functions. Gax is a promising therapeutic gene for dissecting the signaling pathways controlling AF bioactivities....
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PMID: 18187669
PDF is available here.
PDF is available here.
Abstract
Latanoprost induced collagen gel contraction mediated by HTFs. This action of latanoprost appeared to depend on the formation of stress fibers and the activation of MAPKs, FAK, Rho-associated kinase, phospholipase C, and MLC kinase in HTFs. Latanoprost may therefore influence subconjunctival wound h...
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PMID: 18385060
PDF is available here.
PDF is available here.
Abstract
We currently have a poor understanding of the mechanisms that control the growth and activation of fibroblasts in vivo, in part because of a lack of suitable fibroblast markers. We have taken advantage of an antibody previously shown to stain stromal cells in frozen tissues (TE-7) and identified con...
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PMID: 18071065
PDF is available here.
PDF is available here.
Abstract
We cultured human vascular adventitial fibroblasts (hVAFs) from pulmonary arteries and analyzed their characteristics. The doubling time of the hVAFs was 1.5days, and the average number of passage was 11, which was independent of age and sex. The hVAFs were positive for vimentin, collagen type-1, CD...
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PMID: 18230345
PDF is available here.
PDF is available here.
Abstract
We present the first stage in the process of developing a synovial biomembrane for this purpose. Synovial cells harvested from the Achilles tendon sheath and the knee joint of a Wistar albino rat were cultured for 2 weeks in culture medium, and then impregnated into a collagen type 1 matrix for anot...
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PMID: 18181108
PDF is available here.
PDF is available here.
Reproduction (135)3 2008
Abstract
We investigated whether c-kit receptor-positive cells also exist in the normal human VD. Enzyme and fluorescence immunohistochemical techniques were applied on serial sections of human proximal, middle, and distal VD segments (n=49) employing 13 different monoclonal and polyclonal antibodies recogni...
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PMID: 18299431
PDF is available here.
PDF is available here.
Abstract
A dog presented with hematuria, and two small polypoid masses were detected in the urinary bladder. Histopathologically, the masses were located in the mucosal or submucosal layer. That tissue consisted of a random proliferation of spindle-shaped, round and pleomorphic cells with single or multiple...
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PMID: 18388430
PDF is available here.
PDF is available here.
Current Eye Research (33)3 2008
Abstract
Co-treatment of MMC and SAHA efficiently induces apoptosis in TCFs via the up-regulation of p53 and increased phosphorylation of p53 on serine 15 and 392. Also, co-treatment of SAHA and low-dose MMC decreases IOP, prolongs bleb survival, and induces apoptosis of cells under the bleb area following G...
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PMID: 18350434
PDF is available here.
PDF is available here.
Abstract
Partial resistance to mitomycin C after low-dose mitomycin C pre-treatment was significantly neutralised by the addition of verapamil. Low-dose mitomycin C up-regulated P-glycoprotein expression, but not mdr-1 mRNA expression. 5-Fluorouracil did not induce P-glycoprotein expression. P-glycoprotein e...
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PMID: 17934748
PDF is available here.
PDF is available here.
Abstract
We studied human intraarticular fracture-induced hemarthrosis of the knee and attempted to isolate connective tissue progenitors from the hemarthrosis. Hemarthrosis was aspirated from the knee joints of 13 patients suffering from intraarticular osteochondral fractures of the knee. Mononuclear cells...
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PMID: 17763429
PDF is available here.
PDF is available here.
Acta Physiologica (192)2 2008
Abstract
This article reviews the current status of research about the histogenesis and morphofunctional characteristics of chromaffin cells in the adrenal medulla. First, this study reports the selective migration, transcription and activation factors, and the morphological events of the chr...
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PMID: 18021326
PDF is available here.
PDF is available here.
Molecular Vision (14) 2008
Abstract
All the results demonstrate that CS-g-(PEI-b-mPEG) is a promising candidate for siRNA delivery, featuring excellent biocompatibility, biodegradability, and transfection efficiency. The RNA interference (RNAi) strategy using cationic copolymers as siRNA carriers will be a safe and efficient anti-scar...
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PMID: 19137061
PDF is available here.
PDF is available here.
Abstract
We hypothesize that (S)-albuterol could stimulate myofibroblast secretion and expression of VEGF and fibronectin in the presence of Dermatophagoides pteronyssinus extract. Cultured NHLFs were stimulated with IL-1beta, TGF-beta, D. pteronyssinus, and treated with (R)- and (S)-enantiomers of albuterol...
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PMID: 18430317
PDF is available here.
PDF is available here.
Biomaterials (29)1 2008
Human mesenchymal stem cell differentiation to NP-like cells in chitosan-glycerophosphate hydrogels.
Abstract
We have studied the temperature-sensitive hydrogel chitosan-glycerophosphate (C/Gp), seeded with human MSCs and cultured for 4 weeks in standard medium. We have analysed the gene and protein expression profile of the MSCs and compared it to that of both nucleus pulposus (NP) cells and articular chon...
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PMID: 17920676
PDF is available here.
PDF is available here.
Interstitial Cajal-like cells in rat mesentery: an ultrastructural and immunohistochemical approach.
Abstract
We describe a cell type of rat mesentery sharing ultrastructural and immunohistochemical features with ICLC. Mesenteric ICLC were demonstrated by transmission electron microscopy (TEM) and further tested by light microscope immunohistochemistry. The cell described here fulfils the TEM diagnostic cri...
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PMID: 18194443
PDF is available here.
PDF is available here.
Lakartidningen (105)14 2008
Abstract
Abstract
Y-27632 had profound effects on activities of HTFs and was effective in preventing fibroproliferation and scar formation in a rabbit model of glaucoma surgery. A ROCK inhibitor may be an effective anti-scarring agent after glaucoma filtering surgery....
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PMID: 18055804
PDF is available here.
PDF is available here.
Abstract
These results suggest that PC(MECH) are recently generated, short-living PC, and PC(COLL) constitutes a subset with higher maturity and survival, which resides in connective tissue-rich areas....
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PMID: 17827343
PDF is available here.
PDF is available here.
Abstract
Implantation of PLAC cubes with or without gelatin microspheres releasing 100 microg of b-FGF is able to induce fibrous tissue in the post-pneumonectomy dead space....
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PMID: 17766134
PDF is available here.
PDF is available here.
Hepatology (46)5 2007
Abstract
We observed that fibroblasts remained in a mesenchymal-epithelial transition state after hepatocyte differentiation. Moreover, FDHLCs lost their hepatocyte-like phenotype after dedifferentiation. In vivo, human fibroblasts infused directly into the liver of hepatectomized severe combined immunodefic...
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PMID: 17969047
PDF is available here.
PDF is available here.
Folia morphologica (66)4 2007
Abstract
We observed that the initial zone of the AV node is created by an assembly of cells typical for a conduction system that can create three groups that are initially independent of each other and are always arranged around the AV nodal artery. In all the hearts examined we found at least two initial p...
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PMID: 18058749
PDF is available here.
PDF is available here.
Abstract
Stichopin, a 17-amino acid peptide isolated from a sea cucumber, affects the stiffness change of the body-wall catch connective tissues and the contraction of the body-wall muscles. The localization of stichopin in sea cucumbers was studied by indirect immunohistochemistry using antiserum against st...
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PMID: 17623636
PDF is available here.
PDF is available here.
Abstract
We found synergistic effects in assays that evaluated different aspects of cell function. The amount of scarring in an animal experiment was inhibited to a level comparable with a high single dose of mitomycin. Combination therapy of two antiproliferative acting substances may be a promising concept...
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PMID: 17318565
PDF is available here.
PDF is available here.
Journal of Glaucoma (16)5 2007
Abstract
ICG at concentrations of 0.5% and below do not reduce proliferation of Tenon capsule fibroblasts. ICG did not potentiate or diminish the effect of MMC on Tenon capsule fibroblast proliferation....
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PMID: 17700291
PDF is available here.
PDF is available here.
Journal of Biological Chemistry (282)31 2007
Abstract
We demonstrated that transforming growth factor (TGF) beta1 drives fibrocyte-to-myofibroblast differentiation through activating Smad2/3 and SAPK/JNK MAPK pathways, which in turn stimulates alpha-smooth muscle actin expression. We determined that SAPK/JNK signaling acts in a positive feedback loop t...
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PMID: 17556364
PDF is available here.
PDF is available here.
Stem Cells (25)7 2007
Abstract
Using a variety of cell separation techniques and cultivation conditions, circulating, adherent, connective tissue, clonogenic cells were found in just 3 donors out of 66, demonstrating that these precursors are extremely rare in postnatal human blood. Contrary to humans, guinea pig blood shows much...
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PMID: 17464083
PDF is available here.
PDF is available here.
Abstract
These data provide the first evidence for the expression of SMCT1 and SMCT2 in the retina and for the cell-type specific distribution of these transporters within the retina. These studies suggest that SMCT1 and SMCT2 play a differential role in monocarboxylate transport in the retina in a cell type...
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PMID: 17591909
PDF is available here.
PDF is available here.
Abstract
Valve ICs generated an average peak force of 30.9 +/- 10.4 dynes over a 24-h period which, unlike other cell types tested, increased as cell density decreased (R = 0.67, p <0.0001). The temporal pattern of force generation in mitral valve cells was significantly faster than in aortic or tricuspid ce...
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PMID: 17702371
PDF is available here.
PDF is available here.
Abstract
I collagen, fibrin glue, hyaluronan, or sea sponge was inserted into silicone chambers containing the epigastric artery and vein, one end was sealed with adipose tissue and the other with bone wax, then incubated subcutaneously. After 2, 4, or 6 weeks, tissue from chambers containing collagen I, fib...
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PMID: 17106890
PDF is available here.
PDF is available here.
Abstract
Our results indicated that a moderate foreign body reaction was found in control scaffolds, which lasted for 4 weeks. The addition of rhBMP2 to this novel scaffold dramatically alleviated the adverse responses to PLLA. Enhanced deposition of collagen matrix and endochondral formation were observed i...
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PMID: 17226806
PDF is available here.
PDF is available here.
Abstract
The mean cross-sectional areas of fibrovascularization at 2 and 3 weeks after implantation were the greatest in the RGD group, followed by the PAA group. While minimal fibrovascular ingrowths were noted in all implants at 1 week, all the implants showed nearly complete ingrowth at 4 weeks. Blood ves...
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PMID: 17119998
PDF is available here.
PDF is available here.
Abstract
Homeostasis of articular cartilage and subchondral bone are essential for maintaining the integrity of osteochondral structures within synovial joints. This is achieved by the regulation of a delicate balance between anabolic and catabolic signals. In articular cartilage one cell type, the chondrocy...
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PMID: 17414953
PDF is available here.
PDF is available here.
Abstract
In contrast to many rodent models of glaucoma, since the tree shrew optic nerve resembles that in humans, especially at the LC, the tree shrew offers an ideal opportunity to investigate glaucoma pathophysiology in a subprimate model....
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PMID: 17460272
PDF is available here.
PDF is available here.