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Giant Cells (2):
Recent article
Giant Cells
Abstract
We characterized the F strain of herpes simplex virus-1 passaged in the presence of a natural carrageenan isolated from the red seaweed Gigartina skottbergii in view of the virulence for mice of isolated viral clones.
Viral clones (syn14-1 and syn17-2) showed a syncytial phenotype an...
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PMID: 22256337
PDF is available here.
PDF is available here.
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Cancer Science (101)11 2010
Abstract
We identified an SP in the HL cell lines, KMH2 and L428. This SP almost entirely consists of distinct small mononuclear cells, whereas the non-SP is a mixture of relatively large cells with H or RS cell-like morphology. Culture of the small mononuclear cells in the SP from KMH2 generated a non-SP. S...
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PMID: 20735433
PDF is available here.
PDF is available here.
Abstract
We assessed quantitative (number of syncytial knots and number of syncytial nuclei per syncytial knot) and qualitative (density and surface area) characteristics of syncytial knots in each placental sample. Statistical significance was tested using chi(2)-test, Student's t-test and Mann-Whitney U-te...
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PMID: 20627398
PDF is available here.
PDF is available here.
Abstract
These results suggest that the effects of saquinavir and nelfinavir differ on trophoblast functions.
Copyright 2010 Elsevier Ireland Ltd. All rights reserved....
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PMID: 20591557
PDF is available here.
PDF is available here.
Molecular Immunology (47)11-12 2010
Abstract
We investigated the pattern recognition receptors (PRRs) involved in phagocytosis by TG cells. PRRs such as Toll-like receptors (TLRs) and scavenger receptors play a critical role in the immune response to bacterial pathogens. Among these, we selected TLR2 and class B scavenger receptor type I (SR-B...
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PMID: 20471681
PDF is available here.
PDF is available here.
Abstract
We tried to investigate if solitary oral fibromas also share morphologic features with fibrous papules of the face. For this purpose, we designed a retrospective study retrieving 31 fibromas of the tongue from 30 different patients and studied a control group of 20 fibrous papules of the face from 2...
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PMID: 20421776
PDF is available here.
PDF is available here.
Journal of Immunology (184)12 2010
Abstract
We show that MGC formation was reduced when human macrophages were infected with nef-deleted HIV-1. Moreover, expression of Nef, an HIV-1 protein required in several aspects of AIDS, was sufficient to trigger the formation of MGCs in RAW264.7 macrophages. Among Nef molecular determinants, myristoyla...
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PMID: 20488787
PDF is available here.
PDF is available here.
Abstract
We developed a multiscale approach for the computationally efficient modeling of morphogen gradients in the syncytial Drosophila embryo, a single cell with multiple dividing nuclei. By using a homogenization technique, we derived a coarse-grained model with parameters that are explicitly related to...
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PMID: 20479267
PDF is available here.
PDF is available here.
Abstract
Five compounds, styraxjaponoside A (1), matairesinoside (2), egonol glucoside (3), dihydrodehydrodiconiferyl alcohol 9'-O-glucoside (4), and styraxjaponoside B (5) were isolated from the stem bark of Styrax japonica. Among them, compounds 1 and 5 showed significantly high virus-cell fusion inhibitor...
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PMID: 20607490
PDF is available here.
PDF is available here.
Giant cell glioblastoma is associated with altered aurora b expression and concomitant p53 mutation.
Abstract
We analyzed Aurora B expression in gcGB (n = 28) and GB (n = 54) patient tumor samples by immunohistochemistry; 17 gcGB and 22 GB samples were analyzed at the DNA and mRNA levels. No mutations in the Aurora B gene (AURKB) were found, but its mRNA and protein levels were significantly higher in gcGB...
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PMID: 20467329
PDF is available here.
PDF is available here.
Abstract
This study evaluated the response of periapical tissues to the endodontic sealer EndoREZ in root canal fillings short of or beyond the apical foramenlike communication. Twenty root canals of premolars and incisors of 2 mongrel dogs were used. After coronal access and pulp extirpation, the canals wer...
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PMID: 20416527
PDF is available here.
PDF is available here.
Abstract
We identified 37 cases of pleomorphic carcinoma of the breast and evaluated the association between clinical outcome and multiple clinicopathologic features. Patients with invasive pleomorphic lobular carcinoma and those without at least a tissue biopsy before chemotherapy were excluded. Patients ra...
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PMID: 20154588
PDF is available here.
PDF is available here.
Abstract
The presence of osteoclast-like giant cells (OGC) has been reported as a rare and distinct feature in uterine leiomyosarcoma. To present knowledge, 11 cases have been described in the English literature. The authors report an additional example in a 35-year-old woman who presented with a pelvic mass...
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PMID: 20462098
PDF is available here.
PDF is available here.
Abstract
The structural regularities of the organization of interneuronal syncytial cytoplasmic connections between neuronal bodies in gyrus dentatus and CA1 and CA2 (CA is cornu ammonis) of hippocampus, as well as between cell neurites of the caudal mesenteric ganglion were studied by transmission electron...
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PMID: 19947925
PDF is available here.
PDF is available here.
Abstract
Platelet-rich plasma (PRP), containing various growth factors, may speed up wound and bone healing. Using osteoconductive alloplastic materials in reconstructive surgery, the amount of autogenous bone needed can be reduced. The purpose of this experiment was to study the effect of PRP on a mixture o...
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PMID: 20129756
PDF is available here.
PDF is available here.
Planta Medica (76)4 2010
Abstract
Two new lupanes, 2 alpha-acetoxy-3 beta-hydroxy-19 beta-hydrogen-lup-20(29)-en-28-oic acid (2-acetoxyalphitolic acid) ( 1) and 2 alpha-hydroxy-3 beta-acetoxy-19 beta-hydrogen-lup-20(29)-en-28-oic acid (3-acetoxyalphitolic acid) ( 2), together with the known betulinic acid ( 3), betulin ( 4), and sti...
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PMID: 19830655
PDF is available here.
PDF is available here.
Abstract
We suggest that in CGCG and PGCG of the jaws, PTHrP-positive immature osteoblasts activate PTHR1-positive mature osteoblasts to produce RANKL which interacts with RANK on the PTHrP/PTHR1-positive osteoclast-precursor cells found in abundance in the stroma of giant cell lesions and induces osteoclast...
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PMID: 20060342
PDF is available here.
PDF is available here.
Abstract
We first attempted to investigate the SH3BP2 gene in peripheral giant cell lesion (PGCL). The effect of SH3BP2 gene mutations on the transcription of the downstream genes nuclear factor of activated T cells (NFATc1) and the cytokine tumor necrosis factor-alpha (TNF-alpha) was also investigated toget...
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PMID: 20002873
PDF is available here.
PDF is available here.
Abstract
A case of Epstein-Barr virus-related acute giant cell myocarditis in a 16-year-old boy is reported. Fulminant heart failure was successfully treated with extracorporeal membrane oxygenation as a bridge to urgent heart transplantation, and was again necessary after transplantation because of acute ri...
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PMID: 20151055
PDF is available here.
PDF is available here.
Abstract
Our clinicopathologic findings suggest that MNFGCs in an otherwise typical neurofibroma are not a reliable marker of NF1, likely representing a morphological reactive change of the indigenous dermal or endoneurial fibroblasts or dendritic cells in response to unknown microenvironmental stimuli....
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PMID: 19937344
PDF is available here.
PDF is available here.
Acta Cytologica (54)4 2010
Abstract
We describe the cytomorphologic features of cherubism along with its differential diagnosis on cytology and emphasize that with clinicoradiologic correlation, a specific diagnosis can be offered for a definitive therapeutic approach....
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PMID: 20715662
PDF is available here.
PDF is available here.
Abstract
Little attention has been paid to the toxicity of silver amalgam fillings, which have been used over the centuries in Dentistry. Amalgam particles may accidentally and/or traumatically be embedded into the submucosal tissue during placement of a restoration and perpetuate in such area. This article...
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PMID: 20379688
PDF is available here.
PDF is available here.
Acta Cytologica (54)5 Suppl 2010
Abstract
Acta Cytologica (54)5 Suppl 2010
Abstract
Tumoral calcinosis (TC) is a special form of idiopathic calcinosis that affects adolescents and young adults. It is characterized by extensive nonosseous calcification, especially in the periarticular soft tissue regions of major joints.
A young girl presented with recurrent subcutaneous swellings o...
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PMID: 21053587
PDF is available here.
PDF is available here.
Acta Cytologica (54)5 Suppl 2010
Abstract
Malignant mesenchymal tumors constitute < 1% of all malignant neoplasms of the breast. These include pure primary sarcoma of the breast, metastatic sarcoma and sarcomatous patterns in metaplastic carcinomas. On fine needle aspiration cytology (FNAC), the cellular features can suggest the diagnosis o...
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PMID: 21053583
PDF is available here.
PDF is available here.
Acta Cytologica (54)5 Suppl 2010
Abstract
Crohn's disease (CD) can often present initially with extraintestinal manifestations and/or perianal disease. Cytology of such a lesion helps arrive at the diagnosis.
A 27-year-old woman presented with recurrent, painful, discharging perianal lesions. On examination, multiple perianal abscesses, sin...
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PMID: 21053593
PDF is available here.
PDF is available here.
Multinucleate (histiocytic) giant cells in endometrioid adenocarcinoma of the ovary: a rare finding.
Abstract
PLoS Pathogens (6)7 2010
Abstract
We demonstrate that galectin-1 reduces NiV-F mediated fusion of endothelial cells, and that endogenous galectin-1 in endothelial cells is sufficient to inhibit syncytia formation. Galectin-1 regulates NiV-F mediated cell fusion at three distinct points, including retarding maturation of nascent NiV-...
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PMID: 20657665
PDF is available here.
PDF is available here.
Abstract
We describe several hitherto unreported features including juvenile fibroadenoma-like proliferation, fibroadenoma with lactation change, and pseudoangiomatous stromal hyperplasia with multinucleated stromal giant cells in a patient with neurofibromatosis, type 1 all constituting potential diagnostic...
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PMID: 20035149
PDF is available here.
PDF is available here.
Abstract
To solve the problem of the possibility of syncytial connection in the nervous system, this paper for the first time presents the evidence of experimental syncytial fusion of neurons. Neurons, isolated from the ganglia of the mollusc Lymnaea stagnalis and freed from the surrounding glia by pronase tr...
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PMID: 21513099
PDF is available here.
PDF is available here.
Abstract
The paper discusses data on the existence of the syncytial interneuronal connections. Firstly, the discovery of synapses in principle is not a proof of the absence of syncytial connections in the nervous system. Secondly, there is a light microscopical evidence of the existence of the syncytial conne...
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PMID: 20960720
PDF is available here.
PDF is available here.
Abstract
We have shown that adiponectin, an adipokine, has anti-proliferative effects on trophoblastic cells. Here, we complete this study by demonstrating that adiponectin modulates BeWo and human villous cytotrophoblast cell differentiation.
We showed that hCG secretion was up-regulated by adiponectin trea...
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PMID: 21034435
PDF is available here.
PDF is available here.
Abstract
We report that human CD4, the Human Immunodeficiency Virus (HIV) receptor, can be found among the proteins transferred by trogocytosis. CD4 is expressed in a correct orientation after its capture by CD8(+) T cells as shown by its detection using conformational antibodies and its ability to allow HIV...
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PMID: 20368790
PDF is available here.
PDF is available here.
Abstract
The paper is a review of the current state of the important theoretical problem of neurophysiology about the principal possibility of the existence in the nervous system, apart from the major synaptic and contact connections, also of the cytoplasmic syncytial interneuronal connection. Also analyzed...
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PMID: 20209890
PDF is available here.
PDF is available here.
Abstract
A previously healthy 31-year-old Japanese man presented with a very rare germinoma of the corpus callosum without other intracranial lesions manifesting as transitory speech disturbance. Magnetic resonance (MR) imaging revealed a heterogeneously enhanced mass in the corpus callosum extending into th...
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PMID: 20671388
PDF is available here.
PDF is available here.
Abstract
Journal of Virology (84)2 2010
Abstract
We examined the effects of mutations of individual residues of the F protein of Newcastle disease virus, located at critical regions of the protein, such as the C terminus of the N-terminal heptad repeat (HRA) and the N terminus of the C-terminal heptad repeat (HRB). Seven of the mutants were expres...
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PMID: 19906934
PDF is available here.
PDF is available here.
Abstract
Trophoblast giant cells (TGCs) are the first cell type to terminally differentiate during embryogenesis and are of vital importance for implantation and modulation of post-implantation placentation. TGCs are mononuclear and polyploid but are heterogenous and dynamic. At least four different subtypes...
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PMID: 19876834
PDF is available here.
PDF is available here.
Abstract
The common gestational pathologies are placental and developmental in origin. However, much remains to be learned about the key events of morphogenesis and growth in the placenta. Metabolic settings established early in both the fetus and placenta define their capacity to respond to later challenges...
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PMID: 19876840
PDF is available here.
PDF is available here.
Abstract
Our clinicopathologic findings suggest that MNFGCs in an otherwise typical neurofibroma are not a reliable marker of NF1, likely representing a morphological reactive change of the indigenous dermal or endoneurial fibroblasts or dendritic cells in response to unknown microenvironmental stimuli....
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PMID: 19937344
PDF is available here.
PDF is available here.
Abstract
Our clinicopathologic findings suggest that MNFGCs in an otherwise typical neurofibroma are not a reliable marker of NF1, likely representing a morphological reactive change of the indigenous dermal or endoneurial fibroblasts or dendritic cells in response to unknown microenvironmental stimuli....
|
PMID: 19937344
PDF is available here.
PDF is available here.
Abstract
Our clinicopathologic findings suggest that MNFGCs in an otherwise typical neurofibroma are not a reliable marker of NF1, likely representing a morphological reactive change of the indigenous dermal or endoneurial fibroblasts or dendritic cells in response to unknown microenvironmental stimuli....
|
PMID: 19937344
PDF is available here.
PDF is available here.
Abstract
Our clinicopathologic findings suggest that MNFGCs in an otherwise typical neurofibroma are not a reliable marker of NF1, likely representing a morphological reactive change of the indigenous dermal or endoneurial fibroblasts or dendritic cells in response to unknown microenvironmental stimuli....
|
PMID: 19937344
PDF is available here.
PDF is available here.
Abstract
Our clinicopathologic findings suggest that MNFGCs in an otherwise typical neurofibroma are not a reliable marker of NF1, likely representing a morphological reactive change of the indigenous dermal or endoneurial fibroblasts or dendritic cells in response to unknown microenvironmental stimuli....
|
PMID: 19937344
PDF is available here.
PDF is available here.
Abstract
Our clinicopathologic findings suggest that MNFGCs in an otherwise typical neurofibroma are not a reliable marker of NF1, likely representing a morphological reactive change of the indigenous dermal or endoneurial fibroblasts or dendritic cells in response to unknown microenvironmental stimuli....
|
PMID: 19937344
PDF is available here.
PDF is available here.
Abstract
Our clinicopathologic findings suggest that MNFGCs in an otherwise typical neurofibroma are not a reliable marker of NF1, likely representing a morphological reactive change of the indigenous dermal or endoneurial fibroblasts or dendritic cells in response to unknown microenvironmental stimuli....
|
PMID: 19937344
PDF is available here.
PDF is available here.
Abstract
Our clinicopathologic findings suggest that MNFGCs in an otherwise typical neurofibroma are not a reliable marker of NF1, likely representing a morphological reactive change of the indigenous dermal or endoneurial fibroblasts or dendritic cells in response to unknown microenvironmental stimuli....
|
PMID: 19937344
PDF is available here.
PDF is available here.
Abstract
Our clinicopathologic findings suggest that MNFGCs in an otherwise typical neurofibroma are not a reliable marker of NF1, likely representing a morphological reactive change of the indigenous dermal or endoneurial fibroblasts or dendritic cells in response to unknown microenvironmental stimuli....
|
PMID: 19937344
PDF is available here.
PDF is available here.
Abstract
Our clinicopathologic findings suggest that MNFGCs in an otherwise typical neurofibroma are not a reliable marker of NF1, likely representing a morphological reactive change of the indigenous dermal or endoneurial fibroblasts or dendritic cells in response to unknown microenvironmental stimuli....
|
PMID: 19937344
PDF is available here.
PDF is available here.
Abstract
Our clinicopathologic findings suggest that MNFGCs in an otherwise typical neurofibroma are not a reliable marker of NF1, likely representing a morphological reactive change of the indigenous dermal or endoneurial fibroblasts or dendritic cells in response to unknown microenvironmental stimuli....
|
PMID: 19937344
PDF is available here.
PDF is available here.
Abstract
Our clinicopathologic findings suggest that MNFGCs in an otherwise typical neurofibroma are not a reliable marker of NF1, likely representing a morphological reactive change of the indigenous dermal or endoneurial fibroblasts or dendritic cells in response to unknown microenvironmental stimuli....
|
PMID: 19937344
PDF is available here.
PDF is available here.
Abstract
Our clinicopathologic findings suggest that MNFGCs in an otherwise typical neurofibroma are not a reliable marker of NF1, likely representing a morphological reactive change of the indigenous dermal or endoneurial fibroblasts or dendritic cells in response to unknown microenvironmental stimuli....
|
PMID: 19937344
PDF is available here.
PDF is available here.
Abstract
Our clinicopathologic findings suggest that MNFGCs in an otherwise typical neurofibroma are not a reliable marker of NF1, likely representing a morphological reactive change of the indigenous dermal or endoneurial fibroblasts or dendritic cells in response to unknown microenvironmental stimuli....
|
PMID: 19937344
PDF is available here.
PDF is available here.
Virchows Archiv (456)1 2009
Abstract
Our clinicopathologic findings suggest that MNFGCs in an otherwise typical neurofibroma are not a reliable marker of NF1, likely representing a morphological reactive change of the indigenous dermal or endoneurial fibroblasts or dendritic cells in response to unknown microenvironmental stimuli....
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PMID: 19937344
PDF is available here.
PDF is available here.
Abstract
Abstract
This case demonstrates the inertness of PMMA material and reports that a foreign body reaction can be induced following IOL dislocation 28 years after implantation.
Copyright 2009, SLACK Incorporated....
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PMID: 19772265
PDF is available here.
PDF is available here.
Chinese Medical Journal (122)13 2009
Abstract
Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases (32)7 2009
Abstract
A 30-year-old female patient presented with cough and dyspnea on exertion for more than 40 days. She had worked for grinding tungsten rod, with exposure to metal dusts containing cobalt and tungsten for more than 3 years. Chest radiographs and CT demonstrated bilateral ground-glass attenuations and...
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PMID: 19954001
PDF is available here.
PDF is available here.
Kardiologia polska (67)7 2009
Abstract
We present the results of standard transthoracic echocardiographic assessment of a biventricular assist device implanted in a patient with progressive heart failure caused by acute giant-cell myocarditis.
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PMID: 19650006
PDF is available here.
PDF is available here.
Abstract
Laser irradiation of LPS-coated titanium disks significantly reduced LPS-induced nitric oxide production and cell activation by the macrophages and strongly attenuated intercellular adhesion molecule-1 and vascular cell adhesion molecule expression, as well as interleukin-8 production by the endothe...
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PMID: 19485829
PDF is available here.
PDF is available here.