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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Angiotensin-Converting Enzyme Inhibitors (0):
Recent article
Angiotensin-Converting Enzyme Inhibitors
Abstract
Metabolic syndrome (MetS) is characterized by accumulation of visceral fat associated with the clustering of metabolic and pathophysiological cardiovascular risk factors: impaired glucose tolerance, dyslipidemia, and hypertension. Although the definition of MetS is different among co...
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PMID: 21126197
PDF is available here.
PDF is available here.
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Abstract
We ought to better understand these pleiotropic effects for the most effective treatments of hypertension and its complications....
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PMID: 21928691
PDF is available here.
PDF is available here.
Pediatric Research (69)5 Pt 1 2011
Abstract
We investigated the relationship between RAAS and hypoxia in the developing kidney. The expression of VEGF and heme oxygenase (HO)-1 related with the oxygen was analyzed in the enalapril- or spironolactone-treated neonatal rat kidneys. Enalapril (30 mg/kg/d) or spironolactone (200 mg/kg/d) was admin...
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PMID: 21263376
PDF is available here.
PDF is available here.
Pediatric Research (69)5 Pt 1 2011
Abstract
We investigated the relationship between RAAS and hypoxia in the developing kidney. The expression of VEGF and heme oxygenase (HO)-1 related with the oxygen was analyzed in the enalapril- or spironolactone-treated neonatal rat kidneys. Enalapril (30 mg/kg/d) or spironolactone (200 mg/kg/d) was admin...
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PMID: 21263376
PDF is available here.
PDF is available here.
Pediatric Research (69)5 Pt 1 2011
Abstract
We investigated the relationship between RAAS and hypoxia in the developing kidney. The expression of VEGF and heme oxygenase (HO)-1 related with the oxygen was analyzed in the enalapril- or spironolactone-treated neonatal rat kidneys. Enalapril (30 mg/kg/d) or spironolactone (200 mg/kg/d) was admin...
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PMID: 21263376
PDF is available here.
PDF is available here.
Circulation (123)10 2011
Abstract
Arzneimittel-Forschung (61)4 2011
Abstract
The present study was performed to compare the bioavailability of two perindopril erbumine (CAS 107133-36-8) 4 mg tablet formulations (test formulation and reference formulation). This study was a randomized, single-blind, two-period, two-sequence cross-over study which included 20 healthy adult male...
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PMID: 21650082
PDF is available here.
PDF is available here.
Abstract
The efficacy of angiotensin receptor blockers (ARBs) in the management of hypertension is well established. Whether these agents induce pleiotropic effects that promote the amelioration of vascular disorders independent of blood pressure reduction remains controversial. This review e...
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PMID: 21214721
PDF is available here.
PDF is available here.
British Journal of Nutrition (105)2 2011
Abstract
We assessed whether two dietary patterns were effective in lowering BP in persons on antihypertensive therapy and in those not on therapy. Ninety-four participants (38/56 females/males), aged 55·6 (SD 9·9) years, consumed two 4-week dietary regimens in random order (Dietary Approaches to Stop Hype...
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PMID: 20807467
PDF is available here.
PDF is available here.
Abstract
We tested the hypothesis that the combination of angiotensin-converting enzyme inhibitors (ACEi) plus angiotensin II receptor blocker (ARB) can be more effective in decreasing hypertrophy than a largely employed association such as ACEi plus ß-blockers in PPM patients.
We enrolled a total of 72 pat...
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PMID: 21095333
PDF is available here.
PDF is available here.
Ugeskrift for laeger (172)44 2010
Abstract
The American Journal of Medicine (123)11 2010
Abstract
We searched MEDLINE/EMBASE/CENTRAL for articles published from 1990 to the present about randomized clinical trials (RCTs) of ACE inhibitors with a sample size of at least 100 patients in the ACE inhibitors arm with follow-up for at least 3 months and reporting the incidence or withdrawal rates due...
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PMID: 21035591
PDF is available here.
PDF is available here.
The American Journal of Medicine (123)11 2010
Abstract
Abstract
This research study was conducted to investigate whether serum albumin levels predict allograft/patient outcomes in the new era of transplant medicine and immunology.
The association of 1-year post-transplant serum albumin, and patient and graft outcomes was retrospectively analyzed in 500 kidney tr...
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PMID: 20537920
PDF is available here.
PDF is available here.
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition (41)6 2010
Abstract
To investigate the effects of enalapril on the expressions of IL-1beta and IL-6 in the lung of rats treated with acrolein inhalation.
Inflammatory lung injury was induced by acrolein inhalation in rats. The rats were divided into natrium solution (NS) group, acrolein...
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PMID: 21265103
PDF is available here.
PDF is available here.
MMW Fortschritte der Medizin (152)42 2010
Abstract
Circulation Journal (74)11 2010
Abstract
Circulation Journal (74)11 2010
Abstract
Angiotensin II and insulin resistance (IR) have clinical implications in the pathophysiology of chronic heart failure (CHF). However, it is still unclear whether the combination of an angiotensin-receptor blocker and angiotensin-converting enzyme inhibitor (ACEI) improves IR in CHF patients who do n...
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PMID: 20827028
PDF is available here.
PDF is available here.
Abstract
Blood pressure (BP) control is frequently difficult to achieve in patients with predominantly elevated systolic BP. Consequently, these patients frequently require combination therapy including a thiazide diuretic such as hydrochlorothiazide (HCTZ) and an agent blocking the renin-angiotensin-aldoste...
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PMID: 20931100
PDF is available here.
PDF is available here.
Annals of Pharmacotherapy (44)10 2010
Abstract
To review relevant literature supporting the use of β-blockers, angiotensin-converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), diuretics, digoxin, aldosterone antagonists, and vasodilators in the management of heart failure in an elderly patient population aged ≥65 years.
P...
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PMID: 20841514
PDF is available here.
PDF is available here.
Blood Pressure (19)5 2010
Abstract
We studied 20 well controlled hypertensive postmenopausal women who received 6 months of HRT and 6 months of placebo on top of antihypertensive treatment. Two-dimensional M-mode, office blood pressure, 24-h ambulatory blood pressure (ABPM), S-estradiol and S-ACE activity were investigated at baselin...
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PMID: 20486868
PDF is available here.
PDF is available here.
Abstract
Despite the decrease in fasting plasma glucose, telmisartan does not improve insulin sensitivity and substrate utilization. Telmisartan increases plasma leptin as well as insulin-stimulated plasma adiponectin, leptin and resistin, and decreases plasma TNFα during HEC. Changes in plasma adipokines c...
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PMID: 20630944
PDF is available here.
PDF is available here.
La Revue du praticien (60)7 2010
Abstract
Medical management of systolic heart failure is standardized and based on international guidelines. They promote the use of combination therapy based on neurohormonal blockade targeting both the renin-angiotensin system (with ACE inhibitors or ARB) and sympathetic nervous system (i.e., beta blockers...
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PMID: 21033491
PDF is available here.
PDF is available here.
La Revue du praticien (60)7 2010
Abstract
Heart failure is frequently associated with comorbidities, either because of the etiology of heart failure, either because the prevalence of this disease is high in older age groups, who are affected by various pathologies. Hypertension, diabetes and renal failure are the most frequent comorbidities...
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PMID: 21033494
PDF is available here.
PDF is available here.
Kardiologia polska (68)9 2010
Abstract
A 76 year-old woman with a history of coronary artery bypass grafting and prior myocardial infarction was transferred to the emergency room with loss of consciousness due to marked bradycardia caused by hyperkalemia. The concentration of serum potassium was high, and normal sinus rhythm was restored...
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PMID: 20859899
PDF is available here.
PDF is available here.
Abstract
Our understanding of the pathophysiology of AF has increased dramatically over the past few decades. Recent treatment guidelines have heightened our awareness of the challenges involved in the treatment of AF and provided useful recommendations for its diagnosis and management. Because AF is usually...
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PMID: 20562374
PDF is available here.
PDF is available here.
Abstract
We have reviewed the literature examining the benefits and harms of renin-angiotensin system (RAS) blockade in older adults, using studies which included patients with chronic kidney disease (CKD) as well as those which included a broader patient population.
We review the results of key trials which...
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PMID: 20539228
PDF is available here.
PDF is available here.
Abstract
Use of combination therapy whether fixed dose or separate pill combinations is becoming more prevalent. Physicians are not routinely trained in using combinations of different antihypertensive medicines.
Recent outcome trials as well as smaller studies document that meaningful combinations of pharma...
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PMID: 20539227
PDF is available here.
PDF is available here.
Abstract
Diabetic retinopathy remains a leading cause of visual loss worldwide. Patients with diabetes mellitus commonly have multiple comorbidities treated with a wide variety of medications. Systemic medications that target glycemic control and coexisting conditions may have beneficial or d...
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PMID: 20664533
PDF is available here.
PDF is available here.
Abstract
Angiotensin receptor blockers (ARBs) are antihypertensive agents associated with reduced risk of new-onset diabetes mellitus. The ARB telmisartan is a partial agonist of peroxisome proliferator-activated receptor-gamma (PPAR-γ). This study evaluated the effect of telmisartan on insu...
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PMID: 20883237
PDF is available here.
PDF is available here.
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia (21)5 2010
Abstract
Our study revealed that there was a high prevalence of iSRNS and preponderance of non-MCD lesions, with MPGN and FSGS being the major morphologic lesions. The outcome with steroid and cyclophosphamide-based treatment for iSRNS was further enhanced with addition of either lisinopril or spironolactone...
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PMID: 20814150
PDF is available here.
PDF is available here.
Abstract
We also examined immunohistochemical staining for renal alpha-SMA, TGF-beta1, Col IV, and FN in this model. Weak staining was observed in some glomerulus, mesangial cells, and tubular interstitium of sham rats. Staining was markedly enhanced in the majority of glomerulus, mesangial cells, and tubula...
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PMID: 20493835
PDF is available here.
PDF is available here.
Abstract
Voenno-meditsinskii zhurnal (331)8 2010
Abstract
Reninangiotensinaldosterone system is a key link in regulation of blood pressure and causes the target organ damage in hypertensive patients. For many years is not lost interest in the pharmacological blockade of RAAS in order to achieve target levels of BP and prevent damage target organs, particul...
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PMID: 21089428
PDF is available here.
PDF is available here.
Minerva medica (101)4 2010
Abstract
Vascular endothelium is responsible for the secretion of several substances exerting anti-atherogenic effects. Endothelial damage is also crucial for the progress of atherosclerosis and risk factors for atherosclerosis represent crucial factors associated with endothelial dysfunction. Studies have s...
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PMID: 21030938
PDF is available here.
PDF is available here.
Abstract
The mechanism underlying the dermatological manifestations that accompany captopril therapy is not known. The facts that prolidase plays an important role in collagen biosynthesis and that captopril directly inhibits prolidase activity led us to evaluate its effect on collagen biosynthesis in cultur...
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PMID: 20824963
PDF is available here.
PDF is available here.
Abstract
Asymmetric dimethylarginine (ADMA) is an endogenous methylated amino acid derived from arginine which can inhibit the activity of nitric oxide synthases. In various pathological states such as hypercholesterolemia, hyperglycemia, hyperhomocysteinemia, hypertension, coronary artery disease, heart fai...
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PMID: 20824955
PDF is available here.
PDF is available here.
Kidney International (78)3 2010
Abstract
We found that 2 years of oral sodium citrate slowed GFR decline in patients whose estimated GFR (eGFR) was very low (mean 33 ml/min). This treatment also slowed GFR decline in an animal model of surgically reduced nephron mass. Here, we tested if daily oral sodium bicarbonate slowed GFR decline in p...
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PMID: 20445497
PDF is available here.
PDF is available here.
Journal of Hypertension (28)8 2010
Abstract
An increasing number of patients in the community are being treated with angiotensin-converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs) and beta-blockers for hypertension, coronary disease or diabetic renal and vascular complications. Some of these patients will develop heart f...
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PMID: 20613629
PDF is available here.
PDF is available here.
Journal of Biotechnology (148)4 2010
Abstract
Amarantin is the predominant seed storage protein from amaranth. It shows a high content of essential amino acids, making this protein important from a nutritional viewpoint. The protein has two disulfide linked subunits: acidic and basic. Acidic subunit has the potential as a functional and nutrace...
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PMID: 20561545
PDF is available here.
PDF is available here.
Hypertension Research (33)8 2010
Abstract
Hypertension Research (33)8 2010
Abstract
We hypothesized that angiotensin II may also be involved in the remodeling induced by a chronic flow reduction. We analyzed the effect of angiotensin I-converting enzyme inhibition (perindopril) and angiotensin II type 1 receptor blockade (candesartan) on inward remodeling induced by blood flow redu...
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PMID: 20535114
PDF is available here.
PDF is available here.
Hypertension Research (33)8 2010
Abstract
We describe a series of experiments conducted on mice submitted to acute myocardial infarct and treated either with ACE inhibition (which produces potentiation of bradykinin resulting in non-selective B(1)R and B(2)R activation) or with a potent and highly selective B(2)R agonist. These data suggest...
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PMID: 20505673
PDF is available here.
PDF is available here.
Abstract
Examination of 883 cases of AAA repair showed increased mortality associated with preoperative RAS blockade. A better understanding of perioperative pharmacology and physiology of RAS blockade is needed as well as future studies to identify causality....
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PMID: 20524103
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
A total of 17 randomized controlled trials involving 3291 patients were identified using predefined criteria. The combination treatment of amlodipine and angiotensin-converting enzyme inhibitors resulted in a greater reduction of both systolic blood pressure (SBP) [weighted mean difference (WMD) 5.7...
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PMID: 20512032
PDF is available here.
PDF is available here.
Abstract
There is growing interest on how to best tailor blood pressure (BP)-lowering medications according to the circadian (24 h) BP pattern of individual patients, that is, chronotherapy. Significant and clinically meaningful treatment-time differences in the beneficial and/or adverse effects of at least...
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PMID: 20571367
PDF is available here.
PDF is available here.
Abstract
Collapsing glomerulopathy is a form of focal segmental glomerulosclerosis that is usually associated with HIV-1 infection, and is characterized by its poor prognosis and almost inevitable progression to end-stage renal disease. Its pathological features include collapsed glomeruli, podocyte hypertro...
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PMID: 20428916
PDF is available here.
PDF is available here.
Clinical Immunology (136)2 2010
Abstract
We treated MRL-Fas(lpr) mice with imidapril, pravastatin or both agents. Compared with other groups, the mice treated by combination therapy survived longer and showed a significant reduction in proteinuria, renal pathology, including glomerular IgG deposit, and serum anti-DNA Ab. Furthermore, monoc...
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PMID: 20403731
PDF is available here.
PDF is available here.
Journal of Biological Chemistry (285)30 2010
Abstract
We performed microarray gene expression profiling of the aorta during atherosclerosis prevention with the ACE inhibitor, captopril. Atherosclerosis-prone apolipoprotein E (apoE)-deficient mice were used as a model to decipher susceptible genes regulated during atherosclerosis prevention with captopr...
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PMID: 20504763
PDF is available here.
PDF is available here.
The Lancet (376)9736 2010
Abstract
527 participants were randomly assigned to self-management (n=263) or control (n=264), of whom 480 (91%; self-management, n=234; control, n=246) were included in the primary analysis. Mean systolic blood pressure decreased by 12.9 mm Hg (95% CI 10.4-15.5) from baseline to 6 months in the self-manage...
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PMID: 20619448
PDF is available here.
PDF is available here.
Kardiologia polska (68)7 2010
Abstract
The case of woman with dysfunction of left ventricle (LV) possible due to Hodgkin's lymphoma treatment and following myocarditis is presented. Triple therapy with carvedilol, ramipril and spironolactone was continued to prevent further LV remodeling. During 3-years follow-up repeated echocardiograph...
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PMID: 20648444
PDF is available here.
PDF is available here.
Abstract
Abstract
Doxorubicin (DOX), despite causing cardiac toxicity, is an anthracycline chemotherapeutic agent that plays an important role in the treatment of breast cancer. Angiotensin-converting enzyme inhibitors (ACE-I) may protect against cardiac toxicity in patients receiving DOX chemotherapy...
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PMID: 20058065
PDF is available here.
PDF is available here.
Abstract
The efficacy of the combination of angiotensin receptor blockers (ARBs) and angiotensin converting enzyme (ACE) inhibitors in patients of type 1 diabetes mellitus (DM) with nephropathy is debatable. The antialbuminuric efficacy of dual blockade in patients of type 1 DM with micro- or macroabuminuria...
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PMID: 20693588
PDF is available here.
PDF is available here.
Abstract
PURPOSE. To investigate the effects of an angiotensin-converting enzyme (ACE) inhibitor and an angiotensin II antagonist against retinal ischemia-reperfusion injury in the rat retina. METHODS. Retinal ischemia was induced by increasing intraocular pressure to 130 mm Hg. Rats were treated with an ACE...
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PMID: 20164447
PDF is available here.
PDF is available here.
Abstract
IMPORTANCE OF THE FIELD: The increase in type 2 diabetes mellitus is associated to cardiovascular morbidity and mortality. This review focuses on the benefits of the fixed-dose combination of perindopril and indapamide on cardiovascular and renal end points in the ADVANCE (Action in Diabetes and Vas...
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PMID: 20518617
PDF is available here.
PDF is available here.
Abstract
In patients with diabetes and hypertension, combining a renin-angiotensin system blocker with amlodipine, compared with hydrochlorothiazide, was superior in reducing cardiovascular events and could influence future management of hypertension in patients with diabetes. (Avoiding Cardiovascular Events...
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PMID: 20620720
PDF is available here.
PDF is available here.
American Heart Journal (159)6 2010
Abstract
The optimal evidence-based medical therapy is prescribed at suboptimal rates, particularly in patients with high-risk features. New educational strategies are needed to increase the use of these secondary preventive medical therapies.
Copyright 2010 Mosby, Inc. All rights reserved....
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PMID: 20569714
PDF is available here.
PDF is available here.