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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Analgesics (3):
Recent article
Analgesics
MMW Fortschritte der Medizin (153)32-34 2011
Abstract
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Abstract
MMW Fortschritte der Medizin (153)19 2011
Abstract
MMW Fortschritte der Medizin (153)19 2011
Abstract
[How far has our understanding of mechanisms of general anesthesia advanced?: preface and comments].
Abstract
Although the great advance has been made in clinical anesthesia practice, the fundamental mechanisms of anesthetic action still remain to be an unsolved mystery. The early lipid membrane theory based on Meyer and Overton's law was taken over by the proteo-centric view of mechanism. Studies at the mol...
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PMID: 21626856
PDF is available here.
PDF is available here.
Journal of Gastroenterology and Hepatology (26 Suppl 3) 2011
Abstract
The placebo effect has evolved from being considered a nuisance factor in clinical research to a hot topic of scientific investigation. New research findings show that a placebo has real psychobiological and biological effects that are attributable to the overall therapeutic context....
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PMID: 21751434
PDF is available here.
PDF is available here.
Abstract
Ugeskrift for laeger (173)2 2011
Abstract
Herpes zoster (HZ) is a painful vesicular rash localized to one dermatome. Post-herpetic neuralgia (PHN) is persistent pain three months after the rash started. In recent years several Cochrane reviews and clinical studies on how to treat HZ and PHN have been published. These studies show that early...
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PMID: 21219842
PDF is available here.
PDF is available here.
The Lancet (377)9759 2011
Abstract
The Lancet (377)9759 2011
Abstract
The Lancet (377)9759 2011
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Molecular Pain (7)1 2011
Abstract
We previously established a mouse model of FM-like pain, induced by intermittent cold stress (ICS).
In this study, we find that ICS exposure causes a transient increase in plasma corticosterone concentration, but not in anxiety or depression-like behaviors. A single intrathecal injec...
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PMID: 21933442
PDF is available here.
PDF is available here.
Abstract
Abstract
To determine efficacy of a protocol for managing urethral obstruction (UO) in male cats without urethral catheterization.
Clinical trial.
15 male cats with UO in which conventional treatment had been declined.
Laboratory testing and abdominal radiography were performed, and cats with severe metaboli...
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PMID: 21118011
PDF is available here.
PDF is available here.
Abstract
Abstract
Shoulder pain (usually non-traumatic) is the third most common cause of consultations for musculoskeletal pain in primary health care. This article discusses challenges within diagnostics and treatment of non-traumatic shoulder pain.
The article is based on literature identified through a non-system...
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PMID: 21052116
PDF is available here.
PDF is available here.
Abstract
Osteoarthritis is among the most common causes of functional disability and severe pain, and the prevalence of arthritic symptoms among adults is more than 50%. The article discusses epidemiology, pathology and treatment options.
The review is based on a non-systematic search in PubMed and the autho...
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PMID: 21052117
PDF is available here.
PDF is available here.
Abstract
Abstract
Pelvic girdle pain (PGP) usually presents during pregnancy. About 25% of all pregnant women and 5% of all women suffer from postpartum lumbopelvic pain causing them to seek medical help. This article discusses possible causes, diagnostic aspects and treatment of PGP.
The paper is based on literature...
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PMID: 21052118
PDF is available here.
PDF is available here.
Abstract
To evaluate expectations, experiences, and attitudes of orthopedic patients undergoing arthroscopic cruciate ligament reconstruction in terms of postoperative pain and management.
This prospective study involved 115 patients. Preoperatively, patients completed a preoperative questionnaire regarding...
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PMID: 21114205
PDF is available here.
PDF is available here.
Abstract
Our study investigated whether a single 300-mg dose of pregabalin in patients has sufficient central nervous system bioavailability to be useful under acute conditions where brain or spinal cord excitability may lead to long-term disease, such as chronic pain.
Nine patients undergoing primary total...
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PMID: 20975469
PDF is available here.
PDF is available here.
Abstract
We review the pathophysiologic changes associated with major thermal injury in children, the options available for sedation and analgesia for wound care procedures in these children and our institutional guidelines for procedural sedation....
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PMID: 20977331
PDF is available here.
PDF is available here.
Psicothema (22)4 2010
Abstract
This work identifies which psychosocial, clinical and perceived health status factors predict health-resource use in Fibromyalgia (FM), considering the patients' assistance level. Participants were 315 FM patients from Primary Care (PC: n=101) and Rheumatology Services (RS: n=214). Stepwise regressi...
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PMID: 21044477
PDF is available here.
PDF is available here.
Neuroscience (170)2 2010
Abstract
Our recent study has shown that it may inhibit cyclooxygenase-2 (COX-2) in the spinal dorsal horn where COX-2 is upregulated after the development of neuropathic pain following spinal nerve ligation (SNL). The current study directly compared the effect of acupuncture with COX-2 inhibitor celecoxib i...
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PMID: 20654703
PDF is available here.
PDF is available here.
The Journal of Pain (11)10 2010
Abstract
These results suggest that the acute administration of a ROCK inhibitor produces efficacy in both neuropathic and nociceptive pain states at doses devoid of locomotor side effects, with specific effects on WDR neurons. PERSPECTIVE: In this article, the potential analgesic effects of Fasudil in a ran...
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PMID: 20338818
PDF is available here.
PDF is available here.
Pharmaceutical Biology (48)10 2010
Abstract
Our present results demonstrated that the LEO has antinociceptive, anti-inflammatory, and antioxidant properties....
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PMID: 20738158
PDF is available here.
PDF is available here.
Pharmaceutical Biology (48)10 2010
Abstract
Capparis ovata Desf. (Capparaceae) grows widely in Turkey. Flower buds and fruits of the plant are used in folk medicine for their analgesic, antirheumatismal, and diuretic effects.
This study evaluated the possible antinociceptive effect of the methanol extract of C. ovata (CME) in mice.
The antino...
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PMID: 20819022
PDF is available here.
PDF is available here.
Pharmaceutical Biology (48)10 2010
Abstract
We conclude that MECs has antinociceptive and anti-inflammatory activities in rodents....
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PMID: 20695729
PDF is available here.
PDF is available here.
Pharmaceutical Biology (48)10 2010
Abstract
The leaf of sage Salvia officinalis L. (Lamiaceae) is reputed in the folk medicine of Arabia, and Jordan in particular, to relieve pain associated with gastrointestinal disturbance.
Evaluation of the antinociceptive and anti-inflammatory activities of aqueous and butanol extracts of S. officinalis l...
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PMID: 20860437
PDF is available here.
PDF is available here.
Abstract
Of the 75 subjects who were randomized, 68 received at least 1 dose of study medication, and 59 completed the study. Upper limits of the 90% confidence intervals (CIs) for the difference in mean DeltaQTcF between tapentadol IR 100 or 150 mg and placebo were < 10 ms (non-inferiority criterion) for al...
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PMID: 20875374
PDF is available here.
PDF is available here.
Anesthesiology (113)4 2010
Abstract
Cigarette smoke, which serves as a nicotine delivery vehicle in humans, produces profound changes in physiology. Experimental studies suggest that nicotine has analgesic properties. However, epidemiologic evidence shows that smoking is a risk factor for chronic pain. The complex relationship between...
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PMID: 20864835
PDF is available here.
PDF is available here.
Abstract
Cancer pain management is expected to become more important because of the growing number of cancer patients in the years to come. To improve cancer pain relief requires understanding and adequate application of the WHO three-step analgesic ladder. Selective cox-2 inhibitors have efficacy in decreas...
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PMID: 20948246
PDF is available here.
PDF is available here.
Brain research (1352) 2010
Abstract
We acutely injected intrathecal ondansetron in rats between 14 and 30 days after SNL and assessed effects on thermal and mechanical hypersensitivity. We also determined the density of serotonergic nerve fibers, serotonin content and the levels of 5-HT3 receptors within the spinal cord at this time p...
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PMID: 20637741
PDF is available here.
PDF is available here.
Abstract
Abstract
We now show that, whereas blockade of either the extracellular signal-regulated kinase (ERK) pathway or the phosphatidylinositol 3-kinase (PI3K)-Akt pathway alone induced only a low level of cell death, it markedly sensitized NSCLC or CML cells to the induction of apoptosis by histone deacetylase (H...
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PMID: 20026060
PDF is available here.
PDF is available here.
Abstract
Peak plasma gabapentin concentration increased with increasing gabapentin dose. After administration of the 5, 10, and 30 mg/kg doses, median interval until the greatest gabapentin concentration was detected was 60, 120, and 90 minutes, respectively (interval ranges were 60 to 120 minutes, 60 to 120...
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PMID: 20807141
PDF is available here.
PDF is available here.
Abstract
232 patients were included. The mean (range) age was 50 (18-83) years. 63% were women. The mean (range) energy delivery was 89.8 (44.5-158.4) J/cm. There was no significant effect on any outcome related to increasing energy delivery. CONCLUSION: Up to 160 J/cm, increasing energy delivery has no sign...
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PMID: 20510634
PDF is available here.
PDF is available here.
Orthopedics (33)9 2010
Abstract
Abstract
We attempt to update readers on novel developments in the FMS over the last 2 years. We include a discussion of the various pharmacological classes of medications which appear to be of promising potential in this area, including sodium oxybate, dopamine agonists, naltrexone, novel anticonvulsive med...
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PMID: 20486862
PDF is available here.
PDF is available here.
Abstract
Transient receptor potential vanilloid-1 (TRPV1, vanilloid receptor-1) is a nonspecific cation channel that can be activated by multiple endogenous stimuli and by capsaicin, the active ingredient in chili peppers. TRPV1 is expressed predominantly on sensory neurons where it is proposed to serve as a...
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PMID: 20586701
PDF is available here.
PDF is available here.
Abstract
We present a rare case of chemical pneumonitis following accidental lamp oil aspiration characterized by pneumatocele formation and spontaneous resolution. Initial findings on posteroanterior chest radiographs were smoothly circumscribed lower zone masses with and without air-fluid levels. Chest com...
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PMID: 19813175
PDF is available here.
PDF is available here.
Abstract
We confirmed the identity of our cloned cDNA, and found that the BmKAGAP gene contained an intron of 506 bp in length, which was almost identical to that of the characterized scorpion sodium channel ligands in size, consensus junctions, putative branch point and A + T content. This is the first repo...
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PMID: 20433863
PDF is available here.
PDF is available here.
Clinical Journal of Pain (26)7 2010
Abstract
Ziconotide is a nonopioid intrathecal analgesic used to manage moderate to severe chronic pain. Although ziconotide is approved in the United States for intrathecal monotherapy only, it is often used in combination with other intrathecal drugs in clinical practice.
The need exists for a critical ass...
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PMID: 20639730
PDF is available here.
PDF is available here.
Clinical Journal of Pain (26)7 2010
Abstract
We enrolled 15 male (average age 65+/-8.6 y) and 15 female patients (average age 64+/-8.2 y). The male patients had a history of neuropathic pain lasting 15.6+/-8.8 months whereas the female patients had a history of neuropathic pain lasting about 14.9+/-8.6 months. We began with 1 week of patient s...
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PMID: 20639738
PDF is available here.
PDF is available here.
Abstract
The safe prescribing, use, administration, and monitoring of medications are an important component of patient safety efforts and are of particular importance to the obstetrician/gynecologist. Safe use of medications requires a team-based approach focused on medication safety with effective 2-way co...
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PMID: 20661034
PDF is available here.
PDF is available here.
Abstract
Preoperative lornoxicam administration resulted in a significant reduction in pain scores postoperatively in the infiltration and i.v. groups with no significant difference between them. The time to first postoperative analgesic request was 143 +/- 138 min in the control group compared with 684 +/-...
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PMID: 20613539
PDF is available here.
PDF is available here.
Anesthesia & Analgesia (111)3 2010
Abstract
We conclude that gabapentin did not have a detectable effect on the MAC of isoflurane in cats....
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PMID: 20547821
PDF is available here.
PDF is available here.
Abstract
A recently completed study quantified the percent of fentanyl or morphine sulfate lost to uncoated polyvinylchloride (PVC) tubing or to one of two hollow fiber oxygenators within the extracorporeal life support (ECLS) circuit. The results demonstrated the majority of drug loss was due to adsorption...
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PMID: 21114222
PDF is available here.
PDF is available here.
Neurochemical Research (35)9 2010
Abstract
We investigated the ability of CP55,940 and JWH-015 to scavenge reactive oxygen species and their effect on mitochondria permeability transition (MPT) in either a mitochondria-free superoxide anion generation system, intact rat brain mitochondria or in sub-mitochondrial particles (SMP) treated with...
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PMID: 20514518
PDF is available here.
PDF is available here.
Fitoterapia (81)6 2010
Abstract
The anti-inflammatory and analgesic effects of theacrine (1, 3, 7, 9-tetramethyluric acid), a purine alkaloid which is abundantly present in Camellia kucha, were investigated. Xylene-induced ear edema, acetic acid-induced vascular permeability and lambda-carrageenan-induced paw edema were used to in...
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PMID: 20227468
PDF is available here.
PDF is available here.
Abstract
Abstract
These results suggest that long-term treatment of pregabalin may be beneficial in patients with PHN....
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PMID: 20715519
PDF is available here.
PDF is available here.
Abstract
To develop and test two educational programmes (interactive and passive) aimed at improving family doctors' (FD) prescribing practices and patient's knowledge and use of non-opioid analgesics (NOA).
The educational programmes were conducted in two family medicine clinics by using a three-stage appro...
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PMID: 20545804
PDF is available here.
PDF is available here.
Bioresource Technology (101)15 2010
Structure of Agaricus spp. fucogalactans and their anti-inflammatory and antinociceptive properties.
Abstract
Fucogalactans from Agaricus brasiliensis (EPF-Ab) and A. bisporus var. hortensis (EPF-Ah) were prepared via by aqueous extraction and a purification procedure. EPF-Ab had M(w) 19.4 x 10(3)g/mol and EPF-Ah M(w) 31.1 x 10(3)g/mol. EPF-Ab had a (1-->6)-linked alpha-D-Galp main-chain partially substitut...
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PMID: 20363124
PDF is available here.
PDF is available here.
Abstract
We concluded that he had died of pulmonary edema due to combined drug intoxication including proprietary antitussives and cold remedies. Furthermore, there was a strong possibility that he had habitually taken overdoses of those drugs. Herein, the risk of misuse of prescribed and proprietary drugs,...
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PMID: 20106941
PDF is available here.
PDF is available here.
Der Schmerz (24)4 2010
Abstract
The term "peripheral neuropathic pain syndromes" summarizes several chronic pain syndromes, which can occur focally or generalized in the peripheral nervous system in the course of an impairment of afferent neurons. Controlled clinical trials gave distinct indications for systemic treatments with an...
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PMID: 20628765
PDF is available here.
PDF is available here.
Abstract
Population-based modeling is now considered superior to older, more traditional modeling methods. Nonlinear mixed-effect modeling - a commonly used population-based modeling approach - estimates intraindividual and interindividual variability, limits the influence of outlying samples and individuals...
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PMID: 20610985
PDF is available here.
PDF is available here.
Inflammopharmacology (18)4 2010
Abstract
The current study was aimed to evaluate Acacia modesta for analgesic, anti-inflammatory, and anti-platelet activities. The analgesic and anti-inflammatory effects were assessed in rodents using acetic acid and formalin-induced nociception, hot plate and carrageenan-induced rat paw oedema tests. The...
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PMID: 20390366
PDF is available here.
PDF is available here.
Inflammopharmacology (18)4 2010
Abstract
The present study was planned to investigate the antioxidant, antinociceptive, and anti-inflammatory activities of atorvastatin and rosuvastatin (1, 3 and 10 mg/kg, p.o.) in various animal models. The antinociceptive effect was assessed by chemically- (formalin, acetic acid) and thermally- (hot plat...
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PMID: 20532641
PDF is available here.
PDF is available here.
Abstract
We evaluated patient-controlled analgesia use, pain and satisfaction scores, complication rates, and ropivacaine levels associated with the use of periarticular multimodal drug infiltration in THA.
We randomized 64 patients undergoing THA to receive a periarticular intraoperative mul...
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PMID: 20020333
PDF is available here.
PDF is available here.