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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Antidepressive Agents, Second-Generation (0):
Recent article
Antidepressive Agents, Second-Generation
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Abstract
We conducted a PubMed search during June 2009 using the search terms antidepressants and SSRIs (including the names of individual SSRIs: fluoxetine, sertraline, paroxetine, fluvoxamine, citalopram, and escitalopram) in association with bleeding, platelets, hemostasis, nonsteroidal anti-inflammatory...
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PMID: 21190637
PDF is available here.
PDF is available here.
Experimental Neurology (226)2 2010
Abstract
We tested whether such spontaneous fear-like behaviour could be observed in an open-field test 12 h after dlPAG stimulation. Further, we tested whether this fear-like behaviour could be attenuated by acute or chronic administration of buspirone and escitalopram. Our data demonstrate for the first ti...
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PMID: 20837005
PDF is available here.
PDF is available here.
Abstract
The FDA has approved the marketing of an extended-release formulation of trazodone (Oleptro--Angelini Labopharm) for treatment of major depressive disorder in adults. Immediate-release trazodone has been available for treatment of depression for many years, but is used mostly in low doses for its se...
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PMID: 21068704
PDF is available here.
PDF is available here.
Abstract
to report on symptoms and therapies used in childhood narcolepsy-cataplexy.
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PMID: 21102987
PDF is available here.
PDF is available here.
Abstract
We have examined the effects of the dual antidepressant, venlafaxine, on 5-HT(4) receptor-mediated signalling events.
The effects of 21 days treatment (p.o.) with high (40 mg·kg(-1)) and low (10 mg·kg(-1)) doses of venlafaxine, were evaluated at different levels of 5-HT(4) receptor-mediated ne...
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PMID: 20880406
PDF is available here.
PDF is available here.
Psychological Medicine (40)10 2010
Abstract
Concerns have been expressed about possible adverse effects of the use of antidepressant medication during pregnancy, including risk for neonatal pathology and the presence of congenital malformations.
Data from the Swedish Medical Birth Register (MBR) from 1 July 1995 up to 2007 were used to identi...
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PMID: 20047705
PDF is available here.
PDF is available here.
Abstract
This report evaluates the potential of the antidepressant drug citalopram to induce homozygotization of genes previously present in a heterozygous condition, by homologous recombination. In order to address this question, a heterozygous diploid strain of the filamentous fungus Asperg...
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PMID: 20851831
PDF is available here.
PDF is available here.
Abstract
Little is known about the impact of in utero exposure to antidepressants on children's long-term mental health. This study analyzed the impact of exposure to antidepressants during pregnancy on the risk of attention-deficit/hyperactivity disorder (ADHD) in the offspring.
Claims-based data from 38,07...
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PMID: 20613624
PDF is available here.
PDF is available here.
Journal of Affective Disorders (125)1-3 2010
Abstract
I describe, as a first-person narrative, my own experience of psychotic mania, which was suspected to have been induced by the tricyclic antidepressant, dosulepin. I have had a 16-year history of depression and was receiving sertraline 50 mg od when I was prescribed, off licence, dosulepin 25 mg 1-2...
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PMID: 20570368
PDF is available here.
PDF is available here.
Abstract
To our knowledge this is the first reported case of an overdose of Venlafaxine (SNRI) associated Tako Tsubo cardiomyopathy.
Copyright 2010 Elsevier B.V. All rights reserved....
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PMID: 20451358
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
Abstract
It has been recently observed that small fibre neuropathy (SFN) may present as distal symmetrical polyneuropathy and with atypical non-length-dependent pattern.
To describe a small series of patients with non-length-dependent SFN, investigating corneal innervation wit...
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PMID: 20581138
PDF is available here.
PDF is available here.
Consumer Reports (75)7 2010
Abstract
Anesthesia & Analgesia (111)1 2010
Abstract
The combined application of RTX and antidepressants produced a markedly prolonged nociceptive peripheral nerve block in rat sciatic nerves compared with either agent alone. However, the 2-drug regimen also elicited prolonged blockade of the motor function, although disproportionately less compared w...
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PMID: 20519419
PDF is available here.
PDF is available here.
Abstract
Treatment-emergent suicidal ideation was no more common with citalopram than placebo. In participants with baseline suicidal ideation, citalopram reduced suicidal ideation, especially in those whose depressive symptoms responded to treatment.
(c) Copyright 2010 Physicians Postgraduate Press, Inc....
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PMID: 20361918
PDF is available here.
PDF is available here.
Psychiatria Danubina (22)2 2010
Abstract
The results showed that a risk of suicide did not prevent the prescription of venlafaxine, that less venlafaxine was prescribed to male patients than females, and that bipolar II patients were indeed treated with mood stabilisers. DISCUSSION: It appears that in this Community Mental Health Team, the...
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PMID: 20562782
PDF is available here.
PDF is available here.
Psychiatria Danubina (22)2 2010
Abstract
PTSD is a complex disorder, which frequently occurs in comorbidity with anxious disorder, personality disorder, addiction or substance abuse disorder, depressive disorder with or without psychotic symptoms and psychotic disorder. PTSD symptoms may result from deregulation of several different neurot...
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PMID: 20562783
PDF is available here.
PDF is available here.
Psychological Medicine (40)6 2010
Abstract
Patients with BN who fail to report a 60% decrease in the frequency of binge eating or vomiting at week 3 are unlikely to respond to fluoxetine. As no reliable relationships between pretreatment characteristics and eventual response to pharmacotherapy have been identified for BN, early response is o...
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PMID: 20441691
PDF is available here.
PDF is available here.
Abstract
Sleep disorders are among the most common in the general population. Insomnia is a serious clinical and social problems. The prevalence of insomnia in developed countries is estimated at 10-35% (40%). The effective treatment of insomnia, it is essential to proper diagnosis and treatment of the prima...
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PMID: 20642116
PDF is available here.
PDF is available here.
Abstract
Serotonin syndrome is a potentially life-threatening condition caused by excessive serotonergic activity in the nervous system. It is characterized by mental status changes, autonomic instability, and neuromuscular hyperactivity. Most reported cases of serotonin syndrome are in patients using multip...
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PMID: 20433130
PDF is available here.
PDF is available here.
Abstract
I depression following treatment with olanzapine/fluoxetine combination (OFC) or lamotrigine.
Symptom improvement was assessed in 88 OFC-treated and 85 lamotrigine-treated white patients with bipolar I depression in the 7-week acute period of a randomized, double-blind study comparing OFC (6/25, 6/5...
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PMID: 20021991
PDF is available here.
PDF is available here.
Abstract
We designed experiments to evaluate the effects of fluoxetine on the development of oral candidiasis in Sprague-Dawley rats exposed to a chronic auditory stressor. Animals were submitted to surgical hyposalivation in order to facilitate the establishment and persistence of C. albicans infection. Str...
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PMID: 20130126
PDF is available here.
PDF is available here.
CNS Spectrums (15)4 2010
Abstract
Of the participants, 54 patients were found to have compulsive hoarding. Hoarders were significantly more likely than non-hoarding patients to have more severe psychopathology including elevated severity of OCD symptoms, poorer insight, higher prevalence of comorbid schizotypal or obsessive-compulsi...
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PMID: 20414175
PDF is available here.
PDF is available here.
Abstract
Abstract
We report a case of PCA, which initially was diagnosed and treated for about a year as a major depressive episode. While most patients initially present with neurologic symptoms, in some PCA cases secondary manifestations, such as e. g. affective symptoms, might appear before the onset of overt cogn...
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PMID: 20195949
PDF is available here.
PDF is available here.
Abstract
Our findings indicate that antenatal depression and anxiety directly impact postpartum parenting stress, regardless of antenatal AD treatment. Ongoing maternal mental illness in pregnancy is an important predictor of postpartum parenting stress. Early recognition and treatment to remission is key....
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PMID: 20416145
PDF is available here.
PDF is available here.
Pharmacogenomics (11)4 2010
Abstract
The group of patients with intermediate CYP2D6 metabolism (0.5 SGD) had a significantly higher frequency of remitters from major depressive disorder during the 8-week treatment (p = 0.0001). Furthermore, CYP2C19 poor metabolizers had significantly higher S-CIT serum levels than did extensive metabol...
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PMID: 20350136
PDF is available here.
PDF is available here.
Abstract
We have shown before that it is important to simultaneously analyze both pharmacokinetic factors such as the blood concentration and pharmacodynamic factors such as the site of drug action, when searching for genetic information that can be used to predict the treatment effects of fluvoxamine for de...
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PMID: 20491281
PDF is available here.
PDF is available here.
Abstract
We document this clinical phenomenon in several behavioural paradigms. While a single injection of citalopram induced anxiogenic effects, three administrations of citalopram were sufficient to elicit anxiolytic effects. Congruent with these data, we observed that short-term repeated administration o...
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PMID: 20003619
PDF is available here.
PDF is available here.
Abstract
Postgraduate Medicine (122)2 2010
Abstract
Cigarette smoking represents the most important source of preventable morbidity and premature mortality worldwide. Approximately 100 million deaths were caused by tobacco use in the 20th century. There are >1 billion smokers worldwide, and globally the use of tobacco products is incr...
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PMID: 20203458
PDF is available here.
PDF is available here.
Psychological Medicine (40)3 2010
Abstract
Psychological Medicine (40)3 2010
Abstract
Dyadic discord in chronically depressed patients is predictive of a lower likelihood of remission of depression. Couple therapy for those with dyadic discord may increase remission rates....
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PMID: 19607755
PDF is available here.
PDF is available here.
Abstract
We previously reported drug-specific effects of the TCA imipramine and the MAOI phenelzine on HPA axis-relevant endpoints in mice that may explain differential antidepressant responses in melancholic vs. atypical depression. However, selective serotonin reuptake inhibitors (SSRIs) are reported to be...
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PMID: 20374287
PDF is available here.
PDF is available here.
Abstract
Abstract
The mean 8-week increases in QALYs from baseline were 0.0392 and 0.0334 for the ESZ+FLX and PBO+FLX groups, respectively. Mean per-patient costs were USD 1,279 and USD 1,198 for the respective groups. Thus, co-treatment resulted in net increases of 0.0058 QALYs and USD 81, leading to an incremental...
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PMID: 20571180
PDF is available here.
PDF is available here.
CJEM : Canadian journal of emergency medical care = JCMU : journal canadien de soins medicaux d'urgence (12)2 2010
Abstract
We report the case of a patient who presented to the emergency department (ED) with a recent history of generalized tonic-clonic seizures whose etiology was initially a diagnostic mystery. After an initial visit to another ED, the patient presented to our ED later that day with a recurrence of the s...
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PMID: 20219165
PDF is available here.
PDF is available here.
Abstract
A genetic deficiency in sepiapterin reductase leads to a combined deficit of serotonin and dopamine. The motor phenotype is characterized by a dopa-responsive fluctuating generalized dystonia-parkinsonism. The non-motor symptoms are poorly recognized. In particular, the effects of brain serotonin def...
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PMID: 20337188
PDF is available here.
PDF is available here.
Abstract
First, consider possible causes of the inadequate response to an antidepressant, then weigh treatment options in light of the characteristics of the individual patient and therapy. When managing a patient with nonpsychotic depression and inadequate response to the maximum dose of a single antidepres...
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PMID: 20230736
PDF is available here.
PDF is available here.
Abstract
The aim of this study was to analyze the relationship of residual mood and panic-agoraphobic spectrum phenomenology to functional impairment and quality of life in 226 adult outpatients who had remitted from a major depressive episode. Quality of life and functioning were assessed using the Quality...
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PMID: 20061961
PDF is available here.
PDF is available here.
Abstract
At week 24, the mean change from baseline in MADRS total scores was -24.2 for escitalopram-treated patients (n = 141) and -21.5 for paroxetine-treated patients (n = 139) (p < 0.05) in high baseline anxiety patients and the mean change from baseline in HAM-A total score was -17.4 (escitalopram) and -...
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PMID: 20067433
PDF is available here.
PDF is available here.
Abstract
A number of the questions were of low quality and could be omitted in this group of patients. The revised personality profile showed that patients with a higher score for harm avoidance also had a higher depression score measured at discharge from the hospital or during ambulant treatment. CONCLUSIO...
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PMID: 20156404
PDF is available here.
PDF is available here.
Abstract
To determine the effect of serotonin transporter polymorphism promoter region (5-HTTPLR) genotypic variation (low, intermediate, and high expression groups) on response to escitalopram treatment of children and adolescents with autism spectrum disorders (ASDs).
The st...
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PMID: 20020537
PDF is available here.
PDF is available here.
Abstract
Our results suggest that the use of paroxetine in early pregnancy is associated with an increased risk of atrium septum defects. The results stress the importance of studying possible teratogenic effects of a drug, preferably in regard to well-specified malformations....
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PMID: 19937603
PDF is available here.
PDF is available here.
Croatian Medical Journal (51)1 2010
Abstract
MADRS reduction was greater with escitalopram, but 95% confidence intervals (CI) around the mean difference were entirely or largely below 2 scale points (minimally important difference) and CI around the effect size (ES) was below 0.32 ("small") at all time points. Risk of response was higher with...
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PMID: 20162747
PDF is available here.
PDF is available here.
Autism Research (3)1 2010
Abstract
To determine the effect of serotonin transporter polymorphism promoter region (5-HTTPLR) genotypic variation (low, intermediate, and high expression groups) on response to escitalopram treatment of children and adolescents with autism spectrum disorders (ASDs).
The st...
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PMID: 20020537
PDF is available here.
PDF is available here.
Autism Research (3)1 2010
Abstract
To determine the effect of serotonin transporter polymorphism promoter region (5-HTTPLR) genotypic variation (low, intermediate, and high expression groups) on response to escitalopram treatment of children and adolescents with autism spectrum disorders (ASDs).
The st...
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PMID: 20020537
PDF is available here.
PDF is available here.
Autism Research (3)1 2010
Abstract
To determine the effect of serotonin transporter polymorphism promoter region (5-HTTPLR) genotypic variation (low, intermediate, and high expression groups) on response to escitalopram treatment of children and adolescents with autism spectrum disorders (ASDs).
The st...
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PMID: 20020537
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
Abstract
Sexual dysfunctions are the typical symptoms accompanying depressive disorders. However antidepressants which improve general state of the patients have no effect on sexual disorders. Mice of ASC (Antidepressant Sensitive Catalepsy) line with high hereditary predisposition to catalepsy were proposed...
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PMID: 20432724
PDF is available here.
PDF is available here.
Abstract
Several meta-analyses have examined the efficacy of smoking cessation therapies in the general population. However, little is known about the efficacy of these therapies in cardiac patients. Therefore, a meta-analysis of randomized controlled trials (RCTs) was performed to determine the efficacy of...
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PMID: 20151052
PDF is available here.
PDF is available here.
Blood Pressure (19)1 2010
Abstract
This paper describes a clinical picture frequently seen in specialty hypertension clinics, a patient with paroxysmal or intermittent hypertension not related to pheochromocytoma. A variety of diagnostic labels given to these patients is reviewed, including pseudopheochromocytoma and panic attacks. T...
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PMID: 19929288
PDF is available here.
PDF is available here.
Abstract
Combined therapy with adapted IPT was superior to fluoxetine alone in BPD patients, concerning a few core symptoms of the disorder, anxiety, and quality of life....
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PMID: 20181302
PDF is available here.
PDF is available here.
Abstract
Quetiapine (300 or 600 mg/d), but not paroxetine, was more effective than placebo for treating acute depressive episodes in bipolar I and II disorder. Quetiapine treatment was generally well tolerated. TRIAL REGISTRATION: clinicaltrials.gov Identifier: NCT00119652.
Copyright 2010 Physicians Postgrad...
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PMID: 20122366
PDF is available here.
PDF is available here.