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Antidepressive Agents, Tricyclic (0):
Recent article
Antidepressive Agents, Tricyclic
Abstract
We detected no increased risk for perinatal events with fluoxetine therapy compared to the short half-life antidepressants.
clinicaltrials.gov Identifier: NCT00279370.
© Copyright 2011 Physicians Postgraduate Press, Inc....
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PMID: 21824458
PDF is available here.
PDF is available here.
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Ugeskrift for laeger (173)7 2011
Abstract
Ugeskrift for laeger (173)2 2011
Abstract
Herpes zoster (HZ) is a painful vesicular rash localized to one dermatome. Post-herpetic neuralgia (PHN) is persistent pain three months after the rash started. In recent years several Cochrane reviews and clinical studies on how to treat HZ and PHN have been published. These studies show that early...
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PMID: 21219842
PDF is available here.
PDF is available here.
Abstract
Abstract
Varicella-zoster virus (VZV) causes two clinically distinct diseases: varicella and herpes zoster. Herpes zoster, recurrent infection of VZV occurs when the cell-mediated immunity to VZV declines. Since the cell-medicated immunity to VZV declines with aging, herpes zoster occurs more frequently in t...
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PMID: 21077300
PDF is available here.
PDF is available here.
Abstract
to evaluate the efficacy and safety of doxepin 1 mg and 3 mg in elderly subjects with chronic primary insomnia.
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PMID: 21102997
PDF is available here.
PDF is available here.
Abstract
We summarize the clinical evidence regarding somatic interventions associated with switching, with a particular focus on the biologic underpinnings presumably involved in the switch process.
Literature for this review was obtained through a search of the MEDLINE database (1966-2008) using the follow...
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PMID: 20492846
PDF is available here.
PDF is available here.
Psychological Medicine (40)10 2010
Abstract
Concerns have been expressed about possible adverse effects of the use of antidepressant medication during pregnancy, including risk for neonatal pathology and the presence of congenital malformations.
Data from the Swedish Medical Birth Register (MBR) from 1 July 1995 up to 2007 were used to identi...
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PMID: 20047705
PDF is available here.
PDF is available here.
Journal of Affective Disorders (126)1-2 2010
Abstract
We hypothesized that if submissive behavior in DSR is a valid model of depression, it should be possible to show a genetic predisposition for this trait, since clinical studies support a genetic component for depression.
To test this hypothesis, we applied selective breeding on outbred Sabra mice ba...
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PMID: 20427092
PDF is available here.
PDF is available here.
Behavioural Pharmacology (21)5-6 2010
Abstract
We evaluated the effect of tianeptine, an antidepressant with prominent neuroprotective and neuroplastic properties, on the development of morphine antinociceptive tolerance and physical dependence. Male C57BL/6 mice were rendered tolerant to or dependent on morphine by subcutaneously injecting them...
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PMID: 20679893
PDF is available here.
PDF is available here.
Abstract
This study is aimed at investigating the efficacy and tolerability of mirtazapine in a generalized social anxiety disorder. Sixty patients with generalized social anxiety disorder were randomly allocated to receive mirtazapine (30-45 mg/day) (n= 30) or placebo (n= 30) for 12 weeks in a double-blind...
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PMID: 20715300
PDF is available here.
PDF is available here.
Journal of Affective Disorders (125)1-3 2010
Abstract
I describe, as a first-person narrative, my own experience of psychotic mania, which was suspected to have been induced by the tricyclic antidepressant, dosulepin. I have had a 16-year history of depression and was receiving sertraline 50 mg od when I was prescribed, off licence, dosulepin 25 mg 1-2...
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PMID: 20570368
PDF is available here.
PDF is available here.
Abstract
I clinical trials are the next steps to ensuring the efficacy of the treatment.
(c) 2010 Wiley-Liss, Inc. and the American Pharmacists Association...
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PMID: 20213834
PDF is available here.
PDF is available here.
Abstract
Abstract
It has been recently observed that small fibre neuropathy (SFN) may present as distal symmetrical polyneuropathy and with atypical non-length-dependent pattern.
To describe a small series of patients with non-length-dependent SFN, investigating corneal innervation wit...
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PMID: 20581138
PDF is available here.
PDF is available here.
Abstract
We review and compare the use of traditional and new stimulants in the treatment of EDS. For the treatment of cataplexy and automatic behaviors, serotonergic and noradrenergic agents are considered. The role of gamma-hydroxybutyrate (GHB) is also explored in its ability to reduce daytime sleepiness...
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PMID: 20426704
PDF is available here.
PDF is available here.
Anesthesiology (113)1 2010
Abstract
Carbamazepine, lidocaine, and imipramine bind to a common site with the common aromatic motif. External to the aromatic site, there is another weaker and less gating-dependent site for the tertiary amine chain in the latter two drugs. Concomitant clinical use of these drugs, thus, should have at mos...
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PMID: 20526191
PDF is available here.
PDF is available here.
Abstract
Abstract
The extant data do not support the use of SSRIs as first-line treatments for PTSD in children and adolescents. There is limited evidence that the brief use of antiadrenergic agents, second-generation antipsychotics, and several mood stabilizers may attenuate some PTSD symptoms in youth. However, con...
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PMID: 20441729
PDF is available here.
PDF is available here.
Abstract
For medication, psychological, and placebo treatment in FBD, satisfaction with treatment depends on cognitive factors of confidence in treatments, perceived control over illness and symptoms, and reduction in negative cognitions related to symptom experience. Addressing these issues among patients w...
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PMID: 20087332
PDF is available here.
PDF is available here.
Psychiatria Danubina (22)2 2010
Abstract
To accomplish therapeutic goal it is necessary to adjust the dose of medication to be right for every single patient. This procedure of dose adjustment is individualized dose regimen. First of all, pharmacokinetic aspects should be revised, including parameters such as resorption, distribution, meta...
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PMID: 20562781
PDF is available here.
PDF is available here.
Abstract
Abstract
Journal of Clinical Virology (48 Suppl 1) 2010
Abstract
Impairment of varicella zoster virus (VZV)-specific cell-mediated immunity, including impairment due to immunosenescence, is associated with an increased risk of developing herpes zoster (HZ), whereas levels of anti-VZV antibodies do not correlate with HZ risk. This crucial role of VZV-specific cell...
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PMID: 20510262
PDF is available here.
PDF is available here.
Journal of Clinical Virology (48 Suppl 1) 2010
Abstract
We will review the current management strategies available for the treatment of both acute HZ and PHN, including antiviral drugs, analgesic agents, anticonvulsants, tricyclic antidepressants and topical therapies. New molecules in development that show improved activity against VZV are also covered,...
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PMID: 20510264
PDF is available here.
PDF is available here.
Dental update (37)4 2010
Abstract
A number of drug interactions that may potentially occur with local anaesthetic preparations are listed in the British National Formulary (BNF) and Summaries of Product Characteristics (SmPC). Many are theoretical or are associated with higher doses of local anaesthetic preparations than those used...
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PMID: 20527498
PDF is available here.
PDF is available here.
Brain Research Bulletin (81)6 2010
Abstract
A growing body of evidence has pointed to the NMDA receptor antagonists as a potential therapeutic target for the treatment of major depression. The present study was aimed to evaluate behavioural and molecular effects of the acute and chronic treatment with memantine and imipramine in rats. To this...
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PMID: 19954760
PDF is available here.
PDF is available here.
Abstract
The tricyclic antipsychotic and antidepressant drug opipramol (opipramole) was examined with regard to the chemical structure of its organic impurities. Impurities were isolated from the technical product by chromatographic methods and their chemical structures were established by 1H NMR, MS and FTI...
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PMID: 20432617
PDF is available here.
PDF is available here.
Pharmacotherapy (30)4 2010
Abstract
We describe a 43-year-old Caucasian man with major depressive disorder who started mirtazapine 15 mg at bedtime because he had poor symptom control with other antidepressant drugs. Three days later, vivid dream activity was noted, evolving into realistic nightmares that the patient was not able to d...
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PMID: 20334466
PDF is available here.
PDF is available here.
Abstract
It remains unclear whether unipolar psychotic depression should be treated with an antidepressant and an antipsychotic or with an antidepressant alone.
In a multi-center RCT, 122 patients (18-65 years) with DSM-IV-TR psychotic major depression and HAM-D-17 > or = 18 w...
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PMID: 19694628
PDF is available here.
PDF is available here.
Abstract
The anxiolytic-like effects of selective serotonin reuptake inhibitors (SSRIs; paroxetine, fluvoxamine) and serotonin-noradrenaline reuptake inhibitors (SNRIs; milnacipran, venlafaxine) were compared with those of benzodiazepines (diazepam, chlordiazepoxide) and tricyclic antidepressants (imipramine...
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PMID: 20401348
PDF is available here.
PDF is available here.
Molecular Psychiatry (15)3 2010
Abstract
Tianeptine is a clinically used antidepressant that has drawn much attention, because this compound challenges traditional monoaminergic hypotheses of depression. It is now acknowledged that the antidepressant actions of tianeptine, together with its remarkable clinical tolerance, can be attributed...
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PMID: 19704408
PDF is available here.
PDF is available here.
Abstract
INTRODUCTION: Depression is undoubtedly a particularly important disease in terms of personal suffering and death as well as social, family, and economic costs. Pharmacological treatment is a reasonably effective therapeutic approach;however, a delayed therapeutic response and the pe...
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PMID: 21361055
PDF is available here.
PDF is available here.
Abstract
The overall analysis using the convention that a patient is at risk if the HAMD suicide item score is > or =3, and excluding patients at risk at baseline, demonstrated a statistically significantly lower risk for mirtazapine- compared to placebo-treated patients on the HAMD (odds ratio mirtazapine v...
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PMID: 20146649
PDF is available here.
PDF is available here.
Abstract
A selective and reproducible off-line solid-phase microextraction procedure was developed for the simultaneous enantioselective determination of mirtazapine (MRT), demethylmirtazapine and 8-hydroxymirtazapine in human urine. CE was used for optimization of the extraction procedure wh...
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PMID: 20087868
PDF is available here.
PDF is available here.
Abstract
A selective and reproducible off-line solid-phase microextraction procedure was developed for the simultaneous enantioselective determination of mirtazapine (MRT), demethylmirtazapine and 8-hydroxymirtazapine in human urine. CE was used for optimization of the extraction procedure wh...
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PMID: 20087868
PDF is available here.
PDF is available here.
Abstract
A selective and reproducible off-line solid-phase microextraction procedure was developed for the simultaneous enantioselective determination of mirtazapine (MRT), demethylmirtazapine and 8-hydroxymirtazapine in human urine. CE was used for optimization of the extraction procedure wh...
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PMID: 20087868
PDF is available here.
PDF is available here.
Abstract
A selective and reproducible off-line solid-phase microextraction procedure was developed for the simultaneous enantioselective determination of mirtazapine (MRT), demethylmirtazapine and 8-hydroxymirtazapine in human urine. CE was used for optimization of the extraction procedure wh...
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PMID: 20087868
PDF is available here.
PDF is available here.
Abstract
A selective and reproducible off-line solid-phase microextraction procedure was developed for the simultaneous enantioselective determination of mirtazapine (MRT), demethylmirtazapine and 8-hydroxymirtazapine in human urine. CE was used for optimization of the extraction procedure wh...
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PMID: 20087868
PDF is available here.
PDF is available here.
Abstract
A selective and reproducible off-line solid-phase microextraction procedure was developed for the simultaneous enantioselective determination of mirtazapine (MRT), demethylmirtazapine and 8-hydroxymirtazapine in human urine. CE was used for optimization of the extraction procedure wh...
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PMID: 20087868
PDF is available here.
PDF is available here.
Abstract
We report a case of Dothiepin overdose resulting in Brugada like pattern including RBBB which resolved spontaneously....
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PMID: 20653158
PDF is available here.
PDF is available here.
Abstract
Abstract
Tricyclic antidepressants have not been explicitly studied in the conservative treatment of lumbar spinal stenosis. A retrospective chart review was conducted in a subset of patients with chronic low back pain and lumbar spinal stenosis managed with low dose tricyclic antidepressants. Of 26 patients...
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PMID: 20345358
PDF is available here.
PDF is available here.
Abstract
Migraine is a prevalent neurological disorder. Although prevention is the core of treatment for most, some patients are refractory to standard therapies. Accordingly, the aim of this study was to evaluate the use of Quetiapine (QTP) in the preventive treatment of refractory migraine,...
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PMID: 20002594
PDF is available here.
PDF is available here.
Abstract
A binary mixture of imipramine HCl and chlordiazepoxide was determined by three different methods. The first involved determination of imipramine HCl and chlordiazepoxide using the first derivative spectrophotometric technique at 219 and 231.5 nm over the concentration ranges of 1-20 and 2-24 microg...
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PMID: 20629393
PDF is available here.
PDF is available here.
Abstract
Antidepressants are of great interest to clinical and forensic toxicologists as they are frequently used in suicidal gestures; they can be the source of drug interactions and some have narrow therapeutic indices making the potential for toxicity more likely. There are five categories of antidepressa...
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PMID: 20077058
PDF is available here.
PDF is available here.
Abstract
We previously reported that long-term treatment with some antidepressants at low concentrations upregulates BCL2/adenovirus E1B 19-kDa-interacting protein 3 (BNIP3) mRNA expression in NG108-15 cells without causing cell damage, suggesting that BNIP3 is a candidate of intrinsic depressive disorder-re...
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PMID: 20045935
PDF is available here.
PDF is available here.
Pain Medicine (11)1 2010
Abstract
Migraine is a prevalent neurological disorder. Although prevention is the core of treatment for most, some patients are refractory to standard therapies. Accordingly, the aim of this study was to evaluate the use of Quetiapine (QTP) in the preventive treatment of refractory migraine,...
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PMID: 20002594
PDF is available here.
PDF is available here.
Pain Medicine (11)1 2010
Abstract
Migraine is a prevalent neurological disorder. Although prevention is the core of treatment for most, some patients are refractory to standard therapies. Accordingly, the aim of this study was to evaluate the use of Quetiapine (QTP) in the preventive treatment of refractory migraine,...
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PMID: 20002594
PDF is available here.
PDF is available here.
Pain Medicine (11)1 2010
Abstract
Migraine is a prevalent neurological disorder. Although prevention is the core of treatment for most, some patients are refractory to standard therapies. Accordingly, the aim of this study was to evaluate the use of Quetiapine (QTP) in the preventive treatment of refractory migraine,...
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PMID: 20002594
PDF is available here.
PDF is available here.
Pain Medicine (11)1 2010
Abstract
Migraine is a prevalent neurological disorder. Although prevention is the core of treatment for most, some patients are refractory to standard therapies. Accordingly, the aim of this study was to evaluate the use of Quetiapine (QTP) in the preventive treatment of refractory migraine,...
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PMID: 20002594
PDF is available here.
PDF is available here.
Pain Medicine (11)1 2010
Abstract
Migraine is a prevalent neurological disorder. Although prevention is the core of treatment for most, some patients are refractory to standard therapies. Accordingly, the aim of this study was to evaluate the use of Quetiapine (QTP) in the preventive treatment of refractory migraine,...
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PMID: 20002594
PDF is available here.
PDF is available here.
Pain Medicine (11)1 2010
Abstract
Migraine is a prevalent neurological disorder. Although prevention is the core of treatment for most, some patients are refractory to standard therapies. Accordingly, the aim of this study was to evaluate the use of Quetiapine (QTP) in the preventive treatment of refractory migraine,...
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PMID: 20002594
PDF is available here.
PDF is available here.
Pain Medicine (11)1 2010
Abstract
Migraine is a prevalent neurological disorder. Although prevention is the core of treatment for most, some patients are refractory to standard therapies. Accordingly, the aim of this study was to evaluate the use of Quetiapine (QTP) in the preventive treatment of refractory migraine,...
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PMID: 20002594
PDF is available here.
PDF is available here.
Klinicheskaia meditsina (88)6 2010
Abstract
A case of metabolic syndrome is reported in which its elimination before the onset of antiviral treatment of chronic hepatitis A and drug therapy of subsequent depression promoted successful outcome with a stable virological response. Modern approaches are discussed to enhancing effi...
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PMID: 21395034
PDF is available here.
PDF is available here.
Abstract
We measured IFN-gamma levels in the stimulated blood of healthy female subjects in a whole blood assay using the toxic shock syndrome toxin TSST-1 as stimulant. Blood was either supplemented with antidepressants or not.
Mean IFN-gamma concentrations differed between blood with and wi...
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PMID: 21391412
PDF is available here.
PDF is available here.
Abstract
The study confirmed the paucity of adequate safety reporting in trials comparing mirtazapine with other types of antidepressant in the acute-phase treatment of depression in adults. Based on the available evidence, mirtazapine appears to have a unique adverse-event profile. Using these findings, cli...
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PMID: 20030418
PDF is available here.
PDF is available here.
Abstract
Different data show that circulating lymphocytes possess functional serotonin and dopamine transporters (SERT and DAT, respectively). This papers aims to review most of the available literature on this topic, while highlighting the possible role of SERT and DAT, as well as that of their substrates i...
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PMID: 20105129
PDF is available here.
PDF is available here.
Abstract
HA mediated the response to antidepressant treatment, such that any treatment effect of clomipramine occurred through HA reduction. Although replication with multiple assessment periods is required to determine if HA reduction actually precedes depression reduction, the results contribute to a growi...
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PMID: 20090398
PDF is available here.
PDF is available here.