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Psychotropic Drugs (3):
Recent article
Psychotropic Drugs
Abstract
Major depressive disorder, the most common psychiatric illness, is often chronic and a major cause of disability. Many patients with major depressive episodes who have an underlying but unrecognized bipolar disorder receive pharmacologic treatment with ineffective regimens that do no...
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PMID: 21810644
PDF is available here.
PDF is available here.
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Abstract
The purpose of the investigation was to elucidate significance of GABA and dopamine systems of the bed nucleus of stria terminalis for the reinforcing effects of a number of psychotropic drugs (opiates, opioids, psychostimulants) on self-stimulation of the lateral hypothalamus in rat...
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PMID: 21961304
PDF is available here.
PDF is available here.
New England Journal of Medicine (364)21 2011
Abstract
Abstract
Treatments for neuropsychiatric complications of systemic lupus erythematosus are reviewed, including psychiatric medications, corticosteroids (which may also cause psychiatric complications), and emerging non-steroidal immune modulators.
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PMID: 21587003
PDF is available here.
PDF is available here.
Abstract
Although prescriptions for psychotropic medications for children are at an all-time high, medication adherence rates for children are often low. In Part 1 of this article set, literature regarding adherence to psychotropic medications for children was reviewed. Important issues related to adherence...
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PMID: 21117522
PDF is available here.
PDF is available here.
Abstract
Pharmacogenetic testing is used to uncover genetic causes for variations in drug response. Documentation of the method's usefulness in a clinical setting is scarce. The aim of the study was to systematically categorize the experience from routine CYP2D6 genotyping in a diagnostic laboratory.
All sam...
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PMID: 21109842
PDF is available here.
PDF is available here.
Biomedical Chromatography (24)12 2010
Abstract
Many psychotropic substances are illegally available on the streets and/or via the Internet. This wide distribution has become a serious social problem. To control this problem, many substances have been controlled as 'designated substances' (Shitei-Yakubutsu) in Japan since April 2007 by the Pharma...
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PMID: 21077248
PDF is available here.
PDF is available here.
Ugeskrift for laeger (172)45 2010
Abstract
Abstract
We selected 10,002 drivers involved in a traffic accident or violation between 2007 and 2008 in Shanghai, Suzhou and Wuxi. We checked for the presence of psychoactive drugs from blood samples using liquid chromatography tandem mass spectrometry (LC-MS-MS). Of the 10,002 drivers, 10.5% tested positiv...
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PMID: 20728679
PDF is available here.
PDF is available here.
Abstract
The 23rd Congress of the European College of Neuropsychopharmacology (ECNP), held in Amsterdam, included topics covering new therapeutic developments in the field of neuropsychopharmacology. This conference report highlights selected presentations on potential psychotropic drug targets, the relation...
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PMID: 21046518
PDF is available here.
PDF is available here.
Abstract
This article describes several examples where the development of drugs and devices for use in psychiatry followed from initial serendipitous observations. The potential psychotropic properties of chlorpromazine (Thorazine(®)) were first noted in surgical patients when the drug was being investigate...
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PMID: 20873698
PDF is available here.
PDF is available here.
Abstract
Failure to adhere to medication regimens can lead to unnecessary disease progression, disease complications, reduced functional abilities, lower quality of life, and even death. Medication adherence for children taking psychotropic agents poses many special challenges for health care professionals,...
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PMID: 20873702
PDF is available here.
PDF is available here.
Abstract
Experiments on rats showed that mexidol significantly increases local cerebral blood flow in animals under conditions of global transient brain ischemia, whereas in intact rats this drug initially causes a decrease in the blood flow, followed by its recovery. Mechanism of the cerebrovascular effect...
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PMID: 21254506
PDF is available here.
PDF is available here.
Abstract
We investigated the proportion of time and the proportion of visits with symptoms in a cohort of bipolar outpatients followed-up for 18 months, as well as the associated variables.
296 DSM-IV-TR bipolar outpatients were included in a naturalistic longitudinal follow-up study, with quarterly assessme...
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PMID: 20034673
PDF is available here.
PDF is available here.
Der Nervenarzt (81)9 2010
Abstract
Unhindered sexuality plays an important role in the quality of life and this also holds true for patients with psychiatric illnesses. Knowledge concerning the complex neuronal and endocrine control mechanisms of sexual function reveals areas of possible dysfunction caused by the interactions between...
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PMID: 20628721
PDF is available here.
PDF is available here.
Revista de Neurologia (51)4 2010
Abstract
We analyze the connection that takes place between peculiar expressions of religious and mystical exacerbation with respect to some forms of epilepsy, distinguishing between distinct manifestations from those based on its appearance moment within the epileptic moment (ictal, postictal and interictal...
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PMID: 20648467
PDF is available here.
PDF is available here.
Abstract
The CMG demonstrated consistently higher scores on the BART (Days 20 to 40; Mean: CMG, 43.0 to 46.2 and CG, 30.2 to 25.5) and lower levels of arousal on the Affect Grid (Days 7 to 40; Mean: CMG, 6.9 to 6.7 and CG, 8.1 to 8.0) than did the CG. The CMG showed significantly higher performance on the Ar...
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PMID: 20681235
PDF is available here.
PDF is available here.
Abstract
The effect ofpsychotropic drugs on the pharmacological properties of anticonvulsants was studied on white mice under maximal electroshock (ME) test conditions. Changes in the anticonvulsant effect of phenobarbital, diphenin, carbamazepine, hexamidine were traced upon their joint administration with...
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PMID: 20919549
PDF is available here.
PDF is available here.
Abstract
Low testosterone levels in men are associated with the metabolic syndrome (MetS) as well as with depressive symptoms, low vitality, and sexual dysfunction.
To assess the effects of testosterone administration on these subjective symptoms, which have not extensively be...
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PMID: 20524974
PDF is available here.
PDF is available here.
Abstract
Low testosterone levels in men are associated with the metabolic syndrome (MetS) as well as with depressive symptoms, low vitality, and sexual dysfunction.
To assess the effects of testosterone administration on these subjective symptoms, which have not extensively be...
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PMID: 20524974
PDF is available here.
PDF is available here.
Abstract
Low testosterone levels in men are associated with the metabolic syndrome (MetS) as well as with depressive symptoms, low vitality, and sexual dysfunction.
To assess the effects of testosterone administration on these subjective symptoms, which have not extensively be...
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PMID: 20524974
PDF is available here.
PDF is available here.
Abstract
Low testosterone levels in men are associated with the metabolic syndrome (MetS) as well as with depressive symptoms, low vitality, and sexual dysfunction.
To assess the effects of testosterone administration on these subjective symptoms, which have not extensively be...
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PMID: 20524974
PDF is available here.
PDF is available here.
Abstract
Low testosterone levels in men are associated with the metabolic syndrome (MetS) as well as with depressive symptoms, low vitality, and sexual dysfunction.
To assess the effects of testosterone administration on these subjective symptoms, which have not extensively be...
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PMID: 20524974
PDF is available here.
PDF is available here.
Abstract
Anxiety disorders, as a group, are among the most common mental health conditions and frequently cause significant functional impairment. Both psychotherapeutic and pharmacologic techniques are recognized to be effective management strategies. This review provides a discussion of the major classes o...
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PMID: 20667290
PDF is available here.
PDF is available here.
Abstract
Adolescents with severe mental illness are at increased risk for overweight and obesity. Identification of elevated BMI, associated risk factors, and efforts to prevent weight gain should begin at initiation of mental health treatment.
(c) Copyright 2010 Physicians Postgraduate Press, Inc....
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PMID: 20492839
PDF is available here.
PDF is available here.
Abstract
ISSUE: Hypoactive sexual desire disorder (HSDD) is hypothesized to be a disorder of the brain's reward circuitry. Neurotransmitters in reward circuits are thus therapeutic targets for improving sexual desire. Novel treatment strategies are to enhance dopamine (DA) actions, reduce serotonin (5-HT) ac...
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PMID: 20667289
PDF is available here.
PDF is available here.
Abstract
The extant data do not support the use of SSRIs as first-line treatments for PTSD in children and adolescents. There is limited evidence that the brief use of antiadrenergic agents, second-generation antipsychotics, and several mood stabilizers may attenuate some PTSD symptoms in youth. However, con...
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PMID: 20441729
PDF is available here.
PDF is available here.
Abstract
We report on the optimization of the 2-alkoxy-5-methylsulfonebenzoylpiperazine class of GlyT1 inhibitors to improve hERG channel selectivity and brain penetration. This effort culminated in the discovery of compound 10a (RG1678), the first potent and selective GlyT1 inhibitor to have a beneficial ef...
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PMID: 20491477
PDF is available here.
PDF is available here.
La Revue du praticien (60)6 2010
Abstract
Abstract
The sequential model of treatment for depression, i.e. the use of psychotherapy in patients who have remitted from a major depressive disorder after a course of pharmacotherapy, is an intensive two-stage approach that derives from the awareness that one course of treatment is unlikely to provide a s...
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PMID: 20443645
PDF is available here.
PDF is available here.
Abstract
All psychotropic medications have the potential to induce numerous and diverse unwanted ocular effects. Visual adverse effects can be divided into seven major categories: eyelid and keratoconjunctival disorders; uveal tract disorders; accommodation interference; angle-closure glaucoma; cataract/pigm...
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PMID: 20443647
PDF is available here.
PDF is available here.
Abstract
We collected data on the brain function of two affective disorder patients who received psychotropic drug therapy with fNIRS, after written informed consent was obtained. A male patient at first showed a bloodstream drop, seen in the lower inside part of frontal lobe. In both patients, at least a sl...
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PMID: 20666144
PDF is available here.
PDF is available here.
Abstract
We have shown the involvement of the cAMP-CREB cascade in mature granule cells of the dentate gyrus (DG) around stem/progenitor cells in the drug action. To see the direct effect of some psychotropic drugs, we established a culture system of adult rat DG-derived neural precursor cells (ADP). Several...
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PMID: 20666141
PDF is available here.
PDF is available here.
Abstract
To explore the meanings of self-injury and overdosing, and the relationship of each to the other, for women who have fulfilled the diagnostic criteria for borderline personality disorder.
Four women with a history of both self-injury and overdosing were recruited through a local psychotherapy servic...
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PMID: 20021731
PDF is available here.
PDF is available here.
Substance Use and Misuse (45)7-8 2010
Abstract
We collected data from 88 elderly individuals living in nursing homes, home-dwellings, and residential homes between December 2003 and June 2004. We assessed each subject's (1) current (previous four weeks) and chronic (>90 days) psychotropic drug consumption, (2) mood and anxiety (GHQ), and (3) per...
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PMID: 20441450
PDF is available here.
PDF is available here.
Substance Use and Misuse (45)7-8 2010
Abstract
This research was planned for determining the genitourinary health problems of alcohol and other psychoactive substance-dependent women. This research was conducted using a descriptive method at the Alcohol-Substance Research, Treatment and Education Center (ASRTEC). The research sample comprised 12...
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PMID: 20441451
PDF is available here.
PDF is available here.
Psychological Medicine (40)6 2010
Abstract
The ABC is the first self-report that measures patient expectations about the benefits of treatment on everyday functioning, filling an important gap in available assessments of attitudes and expectations about treatment. The ABC is simple, easy to use, and has acceptable psychometric properties for...
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PMID: 19785919
PDF is available here.
PDF is available here.
Psychiatria Danubina (22)2 2010
Abstract
Psychiatria Danubina (22)2 2010
Abstract
We have developed the model of combined treatment for PTSD patients that involves outpatient individual psychotherapy, psychopharmacotherapy and group psychotherapeutic techniques introduced within repeated day-hospital treatments. In this paper the efficiency of the above mentioned model has been e...
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PMID: 20562742
PDF is available here.
PDF is available here.
Psychiatria Danubina (22)2 2010
Abstract
We will present a case of a 58 years old woman who has been suffering from alopecia areata that developed after her husband's death. The patient doesn't function well since then - she is socially isolated, she has lost self confidence and self esteem. As she has realised it was impossible to live li...
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PMID: 20562766
PDF is available here.
PDF is available here.
Psychiatria Danubina (22)2 2010
Abstract
We often come across with prepsychotic and psychotic disorders. When an adolescent patient has a positive hereditary burden for psychiatric illnesses in both parents, then the qualification of adolescent's mental disorder seems closer to psychotic. We must have in mind that hereditary burden is only...
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PMID: 20562788
PDF is available here.
PDF is available here.
Psychiatria Danubina (22)2 2010
Abstract
Numerous epidemiological and clinical studies found a high incidence of comorbidity in children and adolescent psychiatry. In population of children and adolescents is most often described and researched comorbidity of depression, anxiety disorders, than in hyperkinetic and behavioral disorders, and...
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PMID: 20562768
PDF is available here.
PDF is available here.
Psychiatria Danubina (22)2 2010
Abstract
There is a huge gap between possibilities for achieving high treatment effectiveness and poor results in clinical practice. It is possible to achieve a more positive impact and better treatment outcome by individualizing and personalizing treatments in a more creative and rational manner. This revie...
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PMID: 20562771
PDF is available here.
PDF is available here.
Abstract
Abstract
Thus, we concluded that the anticonvulsive properties of narcotic agents have much higher influence than concomitant psychotropic medication. Our data support the view that a significant influence of concurrent psychotropic drugs on seizure adequacy markers is missing, especially when directly compa...
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PMID: 20051218
PDF is available here.
PDF is available here.
Medicina Clínica (134)13 2010
Abstract
PS consumption is a frequent major complaint in an Emergency Department. There are more poly-intoxications in males with psycho-social problems. In those cases, consumption seems to happen regardless of the time in the day or the day of the week....
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PMID: 20304441
PDF is available here.
PDF is available here.
Abstract
Revista Brasileira de Psiquiatria (32 Suppl 1) 2010
Abstract
To review the main advances related to the potential therapeutic use of cannabinoid compounds in psychiatry.
A search was performed in the online databases PubMed, ScieELO, and Lilacs for studies and literature reviews concerning therapeutic applications of cannabinoids in psychiatry, especially can...
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PMID: 20512271
PDF is available here.
PDF is available here.
Abstract
The objective of this epidemiologic transversal cut study was to investigate the consumption of psychoactive substances and their determinants between the nursery academics of the University of Passo Fundo, Rio Grande do Sul State. 266 students, aging more than eighteen years old answered a question...
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PMID: 20464176
PDF is available here.
PDF is available here.
Abstract
CEBRID (Brazilian Center of Information on Psychotropic Drugs) conducted two household surveys on drug use in Brazil, the first in 2001 and the second in 2005, making it possible for researchers, for the first time ever, to have a timeline comparison using this type of methodology. The universe stud...
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PMID: 20464178
PDF is available here.
PDF is available here.
Abstract
The objective of this article is to trace the psychoactive substance use profile among odontology college students from the Espírito Santo Federal University Health Sciences Center. It is an explorative, descriptive, transversal and quantitative study developed with first to last year college stude...
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PMID: 20464177
PDF is available here.
PDF is available here.
Abstract
Cannabis sativa, the most widely used illicit drug, has profound effects on levels of anxiety in animals and humans. Although recent studies have helped provide a better understanding of the neurofunctional correlates of these effects, indicating the involvement of the amygdala and cingulate cortex,...
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PMID: 19775500
PDF is available here.
PDF is available here.
Abstract
Transference-focused psychotherapy is more efficacious than treatment by experienced community psychotherapists in the domains of borderline symptomatology, psychosocial functioning, and personality organisation. Moreover, there is preliminary evidence for a superiority in the reduction of suicidali...
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PMID: 20435966
PDF is available here.
PDF is available here.
Abstract
To identify the types of adverse events associated with psychotropic treatment in African American children and adolescents, analyses were performed using a retrospective cohort design evaluating medical and pharmacy claims from South Carolina's Medicaid program covering outpatient and inpatient med...
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PMID: 20533772
PDF is available here.
PDF is available here.
Child Maltreatment (15)2 2010
Abstract
We used data from the National Survey of Child and Adolescent Well-Being (NSCAW), the Kaiser Family Foundation, and the Area Resource File to examine interstate variations in psychotropic medication use among children coming into contact with child welfare agencies. Mean probabilities of medication...
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PMID: 20410022
PDF is available here.
PDF is available here.
Psychiatrische Praxis (37)4 2010
Abstract
Patients treated by outpatient clinics at psychiatric hospitals suffered from more severe neuropsychiatric symptoms (p < 0.05), were prescribed more antidepressants and antidementia agents (p < 0.05) and, when adjusting for the severity of agitation, less neuroleptics (p < 0.05) as compared to prima...
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PMID: 20225175
PDF is available here.
PDF is available here.
Abstract
Pharmacoeducation can reduce the hospital stays of patients with schizophrenia and schizoaffective disorders, as well as improve their clinical and functional state, likely through better compliance....
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PMID: 20482960
PDF is available here.
PDF is available here.
Abstract
Critically ill patients are at an increased risk to develop drug-drug interactions (DDIs). DDIs that increase the risk of QT prolongation, and ultimately torsades de pointes, can result in a medical emergency. Many clinicians are unaware of the risk of certain drug combinations that may precipitate...
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PMID: 20377471
PDF is available here.
PDF is available here.
Abstract
This research provides a broad view of the nature of psychoactive medication prescribing, which may serve as a guide to future research, policy and education about these medications, their perceived benefits and risks, and their uses....
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PMID: 20297856
PDF is available here.
PDF is available here.