Abstract
High purity water for endocrine disruptors (EDs) analysis in experimental tests is an indispensable requirement for the preparation of reagents and solutions employed in biological laboratories. Commercial ultrapure water may contain traces of organic compounds, which can interfere with in vitro bio...
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PMID: 20382090
PDF is available here.
Abstract
The objective of this study is to investigate the treatment path of metals during the plasma vitrification of fly ash, bottom ash, sludge, and activated carbon collected from a laboratory waste treatment plant. Sampling, digestion, and analysis procedures that followed the standard methods of the Ta...
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PMID: 20437778
PDF is available here.
Abstract
By using a clinical biochemistry laboratory as an example, the authors show how the analytical quality system practically operates. The advantages of using a three-level model for analytical quality requirements on the basis of biological variations in analytes are discussed. Only does the use of a...
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PMID: 20050282
PDF is available here.
Abstract
We have tested aqueous arginine solution for washing and elution of the resin. To our surprise, bound antibody and Fc-fusion protein eluted at pH 7.0 using 1M arginine solution. Various solvent additives were then examined at pH 7.0. Among the tested additives, urea and arginine were the only additi...
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PMID: 18848995
PDF is available here.
Abstract
Research laboratories in a university were investigated for air-borne levels of legally designated organic solvents and specified chemical substances. Repeated surveys in 2004-5 (four times in the two years) of about 720 laboratories (thus 2,874 laboratories in total) revealed that the solvent conce...
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PMID: 18413970
PDF is available here.
Abstract
Preliminary data confirm the model. LaboRisCh appears to be a reliable method for chemical risk assessment in research laboratories and similar workplaces....
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PMID: 18689092
PDF is available here.
Abstract
The LaboRisCh algorithm is a practical tool for the first-level assessment of the health risk from chemicals in research laboratories and similar workplaces. Through the assessment of the risk index related to each agent (Ra), the algorithm leads to the calculation of the value of a baseline risk in...
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PMID: 19353966
PDF is available here.
Abstract
We describe a case of anaphylaxis and allergic contact urticaria from occupational airborne exposure to HBTU (o-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate), which is a chemical used widely for solid and solution-phase peptide synthesis. Previously, the use of this chemical...
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PMID: 16861336
PDF is available here.
Abstract
To date, despite extensive investigations, full understanding of the endocannabinoid system remains elusive; in particular, anandamide cellular uptake is a current controversial topic. An iodo-arylazido probe was synthesized from commercially available azelaic acid monomethyl ester, in order to shed...
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PMID: 15938150
PDF is available here.
Abstract
Even large CT examinations (1000 images) were available from hard disk arrays within 4.0 +/- 0.8 s, smaller studies within 1.8 +/- 0.3 s. Radiographic image retrieval from MOD (30 +/- 4.7 s) was more then 50 % faster than from TAPE. For typical cross-sectional studies, the velocity gain amounted to...
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PMID: 15666234
PDF is available here.
Abstract
We report a new strategy for media identification that uses a combination of three relatively simple techniques: Fourier transform infrared (FT-IR) and near infrared (NIR) spectroscopy in conjunction with search libraries, and particle size distribution analysis. The methods are well established and...
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PMID: 15508039
PDF is available here.
Abstract
The induction of many antioxidant and phase II drug-metabolizing enzymes by phenolic antioxidants and electrophilic compounds is regulated at the transcriptional level. The response to these compounds is mediated by the cis-acting antioxidant response element (ARE) found in the promoter of the encod...
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PMID: 15256215
PDF is available here.
Abstract
We developed a serum-free medium that supports cell proliferation and preserves the differentiation potential. Indeed, expression of Sox9 is maintained when the conventionally used serum is substituted for by this defined supplement. Spontaneous cartilage formation after expansion in serum-free medi...
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PMID: 15009940
PDF is available here.
Abstract
This study did not suggest any major cancer risks among Finnish laboratory workers but the follow-up time of the cohort was too short (on an average 15.7 years) to reveal possible cancer risks requiring a longer induction period.
Copyright 2003 Wiley-Liss, Inc....
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PMID: 14502761
PDF is available here.
Abstract
Studies of olfaction and chemesthesis often rely on nominal, liquid-phase dilutions to quantify the chemicals tested, even though the associated vapor concentrations constitute the actual stimuli. For more than a decade now, our systematic studies of the olfactory and chemesthetic potency of members...
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PMID: 12907584
PDF is available here.
Abstract
Basing on toxicological examination performed between December 1, 2001 and November 6, 2002 the analysis of cardiotoxic agents was carried out. As much as 69.7% of 2523 positive results was related to cardiotoxic agents. Ethanol (57.4%) followed by anticholinergic drugs (15.7%), amphetamine (11.6%)...
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PMID: 14569891
PDF is available here.
Abstract
Symptoms experience is the perception of the frequency, intensity, distress, and meaning of symptoms as they are produced and expressed. Symptoms are multiplicative in nature and may act as catalysts for the occurrence of other symptoms. Antecedents to the symptoms experience include demographic, di...
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PMID: 12861321
PDF is available here.
Abstract
The Decree n(o) 25 of the 2nd of February 2002, according to the Directive 98/24/CE, predetermines the general criteria that the employer, operating in situation of production characterized by chemical risk, must conform to. This risk can derive from the effects of dangerous chemical agents present...
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PMID: 15027691
PDF is available here.
Abstract
The Combinatorial Centre of Excellence (CCE) offers a unique opportunity for the exploitation of a broad range of combinatorial methodologies. Many areas of activity are under investigation, including high-throughput X-ray of small molecules, parallel polymer chemistry and the development of new mul...
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PMID: 12470253
PDF is available here.
Abstract
In order to achieve higher levels of harmonisation for the application of the principles of good laboratory practice (GLP), the monitoring Authority has set up for the inspectors some guidelines to conduct inspections, as approved by the National co-ordination committee. The extension of these guide...
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PMID: 12122892
PDF is available here.
Abstract
Histochemistry and histopathology laboratories are extremely dangerous workplaces owing to the abundance of chemical hazards that constitute major safety and health concerns. A brief review is presented of some of the hazards to which laboratory personnel are exposed. These include fixatives, solven...
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PMID: 11482371
PDF is available here.
Abstract
This appendix lists recipes for common reagents and also describes equipment that is typically found in a molecular biology laboratory.
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PMID: 18265030
PDF is available here.
Author(s) unavailable
Abstract
This section describes the preparation of buffers and reagents used in this manual for cell culture, manipulation of tissue, and cell biological methods. Also discussed are special considerations for PCR experiments and for working with RNA.
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PMID: 18228281
PDF is available here.
Abstract
Air samples, representing different types of indoor environments, were collected and analyzed for eight hydrocarbons namely, n-hexane, benzene, heptane, toluene, p- and o-xylene, ethyl benzene and n-decane using a cryogenic preconcentration system and a gas chromatograph with a flame-ionization dete...
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PMID: 10898403
PDF is available here.
Abstract
We identified eight EAG-active peaks as phenol, nonanal, 2-ethylhexanoic acid, octanoic acid, benzoic acid, nonanoic acid, decanoic acid and dimethyl phthalate. The concentrations of benzoic acid and benzaldehyde present in laboratory air were determined. The origin of the substances and importance...
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PMID: 10667991
PDF is available here.
Abstract
The current italian and european directives require as an essential part of preventive procedures the risk assessment in every work setting. This procedure may be however difficult to be applied because of variability and specificity of work environment, work organisation, chemicals ect. It is true...
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PMID: 10911553
PDF is available here.
Abstract
A variant of thin layer headspace (TLHS) analysis with autogenous generation of the liquid sorbent was applied for the determination of volatile organohalogen compounds in urine. The analytes were isolated from the matrix at an elevated temperature in a TLHS column. They were then transported by a s...
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PMID: 10457646
PDF is available here.
Abstract
More than 800 diagnostic laboratories situated throughout the Eur-Asian continent--from the Pacific Coast up to the North Sea littoral--were involved in a common survey of External Quality Assessment (EQA). It consisted of the simultaneous measurement of up to 30 analytes of 'general' clinical chemi...
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PMID: 9476622
PDF is available here.
Abstract
The skin prick test showed 21 employees (12%) to be sensitized to one or more enzymes. Sixteen positive persons also had specific immunoglobulin E. Atopy was distinctly associated with enzyme sensitization. An exposure-response relationship was found for enzyme sensitization and for respiratory symp...
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PMID: 9403470
PDF is available here.