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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Biochemical Processes (60):
- Up-Regulation
- Signal Transduction
- Phosphorylation
- Nitrosation
- Hydroxylation
- Citric Acid Cycle
- Biotinylation
- Aerobiosis
- Osmosis
- Lipogenesis
- Dimerization
- Dealkylation
- Biosynthetic Pathways
- Ubiquitination
- Protein Folding
- Energy Transfer
- Down-Regulation
- DNA Cleavage
- RNA Processing, Post-Transcriptional
- Protein Renaturation
- Molecular Mimicry
- Lipid Peroxidation
- Evolution, Chemical
- Alkylation
- Transcription, Genetic
- Prenylation
- Enzyme Activation
- Electron Transport
- Anaerobiosis
- Protein Multimerization
- Protein Modification, Translational
- Protein Denaturation
- Protein Binding
- Phototrophic Processes
- Hydrolysis
- Hydrogenation
- DNA Replication
- Peptide Biosynthesis
- Lipoylation
- Heterotrophic Processes
- Halogenation
- DNA Methylation
- Biocatalysis
- Autotrophic Processes
- Allosteric Regulation
- Nucleic Acid Renaturation
- Nucleic Acid Hybridization
- Decarboxylation
- Cyclization
- Binding, Competitive
- Substrate Cycling
- Nucleic Acid Denaturation
- Lipolysis
- Esterification
- DNA Repair
- Carbohydrate Metabolism
- Amination
- Protein Carbonylation
- Deamination
- Acylation
Recent article
Biochemical Processes
Kardiologiia (51)8 2011
Abstract
We have analyzed content of chemical elements in left and right ventricular myocardium of patients with ischemic heart disease with progressing heart failure and have shown that during development and progression of heart failure metabolic processes have unidirectional character in myocardium of bot...
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PMID: 21942953
PDF is available here.
PDF is available here.
| < More recent | Older article > |
Human Genetics (128)2 2010
Abstract
We defined four major haplotypes in our population: the two major haplotypes (named haplotypes A and B) bear both the 5383_5397del variant and the two most common SNP sets found in the CEU population. Quantification analysis revealed that genotype B/B had the highest median of mRNA expression levels...
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PMID: 20549518
PDF is available here.
PDF is available here.
FEBS Letters (584)14 2010
Abstract
We show that the homologous to E6AP carboxyl terminus (HECT)-type ubiquitin ligase Smad ubiquitination regulatory factor 1 (Smurf1) interacts with and targets ING2 for poly-ubiquitination and proteasomal degradation. Intriguingly, the ING2 binding domain in Smurf1 was mapped to the catalytic HECT do...
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PMID: 20621832
PDF is available here.
PDF is available here.
Nanotechnology (21)25 2010
Abstract
We introduce a method for the acquisition of single molecule force measurements of ligand-receptor interactions using the photonic force microscope (PFM). Biotin-functionalized beads, manipulated with an optical trap, and a streptavidin-functionalized coverslip were used to measure the effect of dif...
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PMID: 20516583
PDF is available here.
PDF is available here.
FEBS Letters (584)11 2010
Abstract
We show that treating HBV expressing cells with the natural phenolic compound curcumin inhibits HBV gene expression and replication. This inhibition is mediated via down-regulation of PGC-1alpha, a starvation-induced protein that initiates the gluconeogenesis cascade and that has been shown to robus...
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PMID: 20434445
PDF is available here.
PDF is available here.
Metabolic Engineering (12)3 2010
Abstract
These results imply that PHB flux is primarily controlled by the expression levels of the product forming pathway and not by the availability of precursors. These results confirm prior in vitro measurements and metabolic models and show expression level is a major affecter of PHB flux.
2009 Elsevier...
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PMID: 19879956
PDF is available here.
PDF is available here.
Metabolic Engineering (12)3 2010
Abstract
We here describe the metabolic engineering of an artificial pathway that produces 26% EPA in leaf triacylglycerol using a newly-identified Delta6-desaturase from the marine microalga Micromonas pusilla. We also demonstrate that this enzyme appears to function as an acyl-CoA desaturase that has prefe...
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PMID: 20004733
PDF is available here.
PDF is available here.
Abstract
Our studies revealed that AcSDKP levels were markedly elevated in neoplastic diseases including hematologic malignancies and solid neoplasms. Consistent with this finding, the enhanced activity of POP was also detected in all analyzed specimens of cancer tissues. Both these novel findings are in con...
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PMID: 20536450
PDF is available here.
PDF is available here.
Genes to Cells (15)4 2010
Abstract
These results suggest that sarcoma cells overexpressing PER2 suppress tumors in vivo by changing the nature of tumor cell adhesion....
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PMID: 20236181
PDF is available here.
PDF is available here.
Genes to Cells (15)4 2010
Abstract
These results suggest that sarcoma cells overexpressing PER2 suppress tumors in vivo by changing the nature of tumor cell adhesion....
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PMID: 20236181
PDF is available here.
PDF is available here.
Genes to Cells (15)4 2010
Abstract
These results suggest that sarcoma cells overexpressing PER2 suppress tumors in vivo by changing the nature of tumor cell adhesion....
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PMID: 20236181
PDF is available here.
PDF is available here.
Genes to Cells (15)4 2010
Abstract
These results suggest that sarcoma cells overexpressing PER2 suppress tumors in vivo by changing the nature of tumor cell adhesion....
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PMID: 20236181
PDF is available here.
PDF is available here.
Genes to Cells (15)4 2010
Abstract
These results suggest that sarcoma cells overexpressing PER2 suppress tumors in vivo by changing the nature of tumor cell adhesion....
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PMID: 20236181
PDF is available here.
PDF is available here.
Genes to Cells (15)4 2010
Abstract
These results suggest that sarcoma cells overexpressing PER2 suppress tumors in vivo by changing the nature of tumor cell adhesion....
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PMID: 20236181
PDF is available here.
PDF is available here.
Genes to Cells (15)4 2010
Abstract
These results suggest that sarcoma cells overexpressing PER2 suppress tumors in vivo by changing the nature of tumor cell adhesion....
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PMID: 20236181
PDF is available here.
PDF is available here.
Lab On a Chip (10)4 2010
Abstract
The ambition of lab-on-a-chip (LOC) systems to achieve chip-level integration of a complete analytical process capable of performing a complex set of biomedical protocols is hindered by the absence of standard fluidic components able to be assembled. As a result, most microfluidic platforms built to...
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PMID: 20126681
PDF is available here.
PDF is available here.
Abstract
Cell migration and invasion are crucial steps in many physiological events. However, they are also implicated in the physiopathology of many diseases, such as cancer. To spread through the tissues, tumor cells use mechanisms that involve several molecular actors: adhesion receptor families, receptor...
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PMID: 20348621
PDF is available here.
PDF is available here.
Abstract
Experiment shows that our algorithm is able to give comprehensible visualization for pathways with hierarchies, cycles as well as complex structures. It clearly renders the global component structures as well as the local structure in each component. In addition, it runs very fast, and gives better...
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PMID: 20036522
PDF is available here.
PDF is available here.
Abstract
The practicability of our approach is illustrated with two case studies. The first study shows that our approach allows to conclusively rule out wrong model hypotheses. The second study focuses on parameter estimation, and shows that the proposed method allows to evaluate the global influence of mea...
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PMID: 20500862
PDF is available here.
PDF is available here.
Nature Materials (8)8 2009
Sequential click reactions for synthesizing and patterning three-dimensional cell microenvironments.
Abstract
Click chemistry provides extremely selective and orthogonal reactions that proceed with high efficiency and under a variety of mild conditions, the most common example being the copper(I)-catalysed reaction of azides with alkynes. While the versatility of click reactions has been broadly exploited, a...
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PMID: 19543279
PDF is available here.
PDF is available here.
Cancer Biology & Therapy (8)10 2009
Abstract
Abstract
Hereditas (Beijing) (31)2 2009
Abstract
Prion protein (PrP) is a pathogeny identified in recent years, which infects both mankind and other mammals. It has been proved that PrP is a sole protein able to duplicate and propagate with itself. PrP can express in many tissues and has important physiological functions in many species of animals...
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PMID: 19273420
PDF is available here.
PDF is available here.
Renal Failure (31)5 2009
Abstract
In 2007, there was emerging toxic nephropathy due to melamine. Renal failure due to melamine crystal is noted in cases of melamine intoxication. In this article, the author studies the melamine crystal by the molecular docking technique and found that the size of crystal is a possible explanation fo...
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PMID: 19839845
PDF is available here.
PDF is available here.
Abstract
Aldehyde oxidase (AO) is a homodimer with a subunit molecular mass of approximately 150 kDa. Each subunit consists of about 20 kDa 2Fe-2S cluster domain storing reducing equivalents, about 40 kDa flavine adenine dinucleotide (FAD) domain and about 85 kDa molybdenum cofactor (MoCo) domain containing...
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PMID: 19122276
PDF is available here.
PDF is available here.
Abstract
Elementary mode analysis is a useful metabolic pathway analysis tool to identify the structure of a metabolic network that links the cellular phenotype to the corresponding genotype. The analysis can decompose the intricate metabolic network comprised of highly interconnected reactions into uniquely...
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PMID: 19015845
PDF is available here.
PDF is available here.
Artificial Life (15)1 2009
Abstract
We illustrate four models of biochemical pathways described in our artificial chemistry based on string pattern matching and recombination. The modeled pathways are the replication of DNA, transcription from DNA to mRNA, translation from mRNA to protein, and the oxidation of fatty acids. The descrip...
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PMID: 18855562
PDF is available here.
PDF is available here.
Artificial Life (15)1 2009
Abstract
We propose a hierarchical model for the biomolecular covalent bond (HBCB model). This model assumes that terrestrial organisms arrange their biomolecules in a hierarchical structure according to the energy strength of their covalent bonds. It also assumes that they have evolutionarily selected the P...
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PMID: 18855570
PDF is available here.
PDF is available here.
Artificial Life (15)1 2009
Abstract
We review mathematical approaches that exploit the stoichiometric structure, which can be seen as a particular directed hypergraph, to derive an algebraic picture of chemical organizations. We then give an alternative interpretation in terms of set-valued set functions that encapsulate the productio...
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PMID: 18855563
PDF is available here.
PDF is available here.
Artificial Life (15)1 2009
Abstract
We construct functional motifs from the bottom up. We formulate conceptual networks of biochemical reactions that implement elementary algebraic operations over the domain and range of positive real numbers. We discuss how the steady state behavior relates to algebraic functions, and study the stabi...
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PMID: 18855568
PDF is available here.
PDF is available here.
Abstract
We used a transgenic Drosophila model to analyze whole-genome transcriptional profiles in flies that express human wild-type or mutant MYOC in their eyes. The transgenic flies display ocular fluid discharge, reflecting ocular hypertension, and a progressive decline in their behavioral responses to l...
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PMID: 19148291
PDF is available here.
PDF is available here.
Abstract
We have proposed a new D(P)/L(P) stereochemical notation for P-chiral dinucleoside monophosphate analogues based on a structural relationship between compounds. As an extension of this work, we present here applications of the D(P)/L(P) notation for tracking stereochemistry of reaction pathways invo...
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PMID: 19116868
PDF is available here.
PDF is available here.
BMC Bioinformatics (10)1 2009
Abstract
In this study we introduce a constrained optimization method for estimating parameter values of biochemical pathway models using steady-state information and transient measurements. The constraints are derived from the flux connectivity relationships of the system at the steady state. Two case studi...
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PMID: 19432964
PDF is available here.
PDF is available here.
Abstract
We predict computationally and analytically that any organism evolving to maximize growth rate, ATP production, or any other linear function of metabolic fluxes tends to significantly reduce the number of active metabolic reactions compared to typical nonoptimal states. The reduced number appears to...
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PMID: 19057639
PDF is available here.
PDF is available here.
Abstract
We examine the dynamic interaction between the developing epithelia and the extracellular matrix, and discuss how similar interactions are exploited by the genetically modified epithelium during tumor progression. We emphasize the process of mechanoreciprocity, which is a phenomenon observed during...
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PMID: 19029939
PDF is available here.
PDF is available here.
Abstract
We have developed a spectroscopic model of glioma to quantify these chemical changes. The model constructed includes individual FT-IR spectra of normal and glioma brain constituents such as lipids, DNA, and proteins (measured on delipidized tissue). Modeling of FT-IR spectra yielded fit coefficients...
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PMID: 18937421
PDF is available here.
PDF is available here.
Abstract
Oat (Avena sativa L.), a worldwide temperate cereal crop, is deficient in tolerance to osmotic stress due to drought and/or salinity. To genetically transform the available commercial oat cultivars, a genotype-independent and efficient regeneration system from shoot apical meristems was developed us...
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PMID: 19009445
PDF is available here.
PDF is available here.
Chemical Reviews (108)11 2008
Abstract
Chemical Reviews (108)11 2008
Abstract
Biophysical Journal (95)9 2008
Abstract
I are shorter and more dynamic than those of type II, and they contain actin filaments. They are formed when cells explore their surroundings to make contact with another cell. The nanotubes of type II are longer and more stable than type I, and they have cytokeratin filaments. They are formed when...
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PMID: 18658210
PDF is available here.
PDF is available here.
Medicine & Science in Sports & Exercise (40)11 Suppl 2008
Abstract
Over the course of USMC RT, mood and body composition improved substantially and dramatically, an indication of the effectiveness of USMC RT for altering the physical and the cognitive status of trainees....
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PMID: 18849867
PDF is available here.
PDF is available here.
Abstract
We report as oxidative stress may exert deleterious effects in diabetes, as well as address current strategies in study to down-regulating vascular injury....
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PMID: 19082297
PDF is available here.
PDF is available here.
Biosystems (94)1-2 2008
Abstract
We propose a modeling and analysis method for biochemical reactions based on finite state automata. This is a completely different approach compared to traditional modeling of reactions by differential equations. Our method aims to explore the algebraic structure behind chemical reactions using auto...
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PMID: 18606208
PDF is available here.
PDF is available here.