Abstract
The quest for synthetic materials to repair load-bearing bone lost because of trauma, cancer, or congenital bone defects requires the development of porous, high-performance scaffolds with exceptional mechanical strength. However, the low mechanical strength of porous bioactive ceram...
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PMID: 21745606
PDF is available here.
Abstract
The structural basis of the extreme pH dependence of oxygen binding to Root effect Hbs is a long-standing puzzle in the field of protein chemistry. A previously unappreciated role of steric factors in the Root effect was revealed by a comparison of pH effects on oxygenation and oxida...
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PMID: 21745602
PDF is available here.
Abstract
The heat of lysozyme adsorption on mesostructured cellular foam (MCF) silica was measured using flow microcalorimetry (FMC) to investigate the influence of a neutral salt, sodium sulfate. At concentrations up to 0.5 M sodium sulfate, a complex initial exotherm was followed by an endotherm. Protein su...
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PMID: 21835415
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Abstract
Copper complex with Curtis macrocyclic tetramine is offered as reagent for extraction-photometric determination of nonsteroidal anti-inflammatory drugs (NSAIDs), belonging to the class of aromatic carboxylic acids. The studies indicate that this method is suitable for quantitative determination of NS...
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PMID: 21928706
PDF is available here.
Abstract
Two methods for determination of imidapril hydrochloride (IMD) in the form of tablets were developed and the stability-indicative determination of IMD in solid state formulations by means of the proposed methods was investigated. IMD is not a pharmacopeial raw material, therefore there is no official...
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PMID: 21928708
PDF is available here.
Abstract
The present investigation concerns with the development and optimization of a bipolymeric delivery device for the treatment of colonic diseases. Prednisolone - a popular glucorticoid was used a model drug. The formulations were designed with an objective to deliver the drug to the large bowel with a...
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PMID: 21928719
PDF is available here.
Abstract
Vibro cholera neuraminidase is known to cleave sialic acid in the gut to expose receptors for cholera enterotoxin. This study determined if cholera neuraminidase crosses significantly into the circulation of patients with cholera to cause cleavage of sialic acid on circulating blood cells.
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PMID: 21922855
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Abstract
We show that soil nitrite can release HONO and explain the reported strength and diurnal variation of the missing source. Fertilized soils with low pH appear to be particularly strong sources of HONO and OH. Thus, agricultural activities and land-use changes may strongly influence the oxidizing capa...
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PMID: 21852453
PDF is available here.
Abstract
Open-ended, multi-wall carbon nanotubes (CNTs) with magnetic nanoparticles encapsulated within their graphitic walls (magCNTs) were fabricated by a combined action of templated growth and a ferrofluid catalyst/carbon precursor, and tested as drug hosts. The hybrid nanotubes are stable under extreme p...
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PMID: 21817779
PDF is available here.
Abstract
In this paper, a pH-inductive protein-scaffold biosynthesis of shape-tunable crystalline gold nanoparticles at room temperature has been developed. By simple manipulation of the reaction solution's pH, anisotropic gold nanoparticles including spheres, triangles and cubes could be produced by incubati...
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PMID: 21828895
PDF is available here.
Abstract
These results demonstrate that rat MAO A exhibits functional properties similar but not identical with those of the human enzyme and provide additional support for C-H bond cleavage via a polar nucleophilic mechanism....
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PMID: 21819071
PDF is available here.
Abstract
We used shallow water CO(2) vents in the Mediterranean Sea as a model system to examine emergent ecosystem responses to ocean acidification in rocky reef communities. We assessed in situ benthic invertebrate communities in three distinct pH zones (ambient, low, and extreme low), which differed in bo...
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PMID: 21844331
PDF is available here.
Abstract
We have carried out a comparative biochemical-biophysical characterization of the structural and functional properties of recombinant hemoglobins (rHb) from woolly mammoth (rHb WM) and Asian elephant (rHb AE) in relation to human hemoglobins Hb A and Hb A(2) (a minor component of human blood). We ha...
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PMID: 21806075
PDF is available here.
Abstract
These results show that CpOsm is a stable protein, and its antifungal activity involves membrane permeabilization, as property reported earlier for other osmotins and thaumatin-like proteins....
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PMID: 21798235
PDF is available here.
Abstract
The proteome of untreated white wines (a Recioto made with Garganega grapes from the Veneto region) was explored in depth via capture with combinatorial peptide ligand libraries (CPLL) at four different pH values: pH 2.2, 3.8, 7.2, and 9.3. The combined data on the discoveries in the...
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PMID: 21702502
PDF is available here.
Abstract
Iturin A, a powerful antifungal surfactant, is a kind of bacterial lipopeptide produced by Bacillus strains. This study addresses the use of an aqueous two-phase system (ATPS) using ethanol/ammonium sulfate to extract iturin A from Bacillus amyloliquefaciens NJN-6 fermentation broth...
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PMID: 21872538
PDF is available here.
Abstract
Novel nanowall arrays of CaCO(3)-chitosan (CaCO(3)-chi) were deposited onto a cathodic substrate by a facile one-step electrodeposition approach. Results demonstrate that chitosan plays an important role in the formation of nanowall arrays. Freestanding well-aligned CaCO(3)-chi nanow...
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PMID: 21674113
PDF is available here.
Abstract
We review the current knowledge on the molecular stress adaptation responses in L. monocytogenes cells as revealed through transcriptome, proteome, genetic, and physiological analysis. The adaptation of L. monocytogenes to stress exposure is achieved through global expression changes in a large numb...
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PMID: 21495855
PDF is available here.
Abstract
I preparations homogeneous in SDS-PAAG test were obtained by the affinity chromatography on the synthesized sorbent L-arginine-macroporous glass. Some physico-chemical characteristics of the isolated arginase preparation have been estimated: thermo- and pH-stability, temperature- and pH-optima of th...
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PMID: 21805858
PDF is available here.
Abstract
Our strategy is based on facile conjugation of BTZ to catechol-containing polymeric carriers that are designed to be taken up selectively by cancer cells through cell surface receptor-mediated mechanisms. The polymer used as a building block in this study was poly(ethylene glycol) (PEG), chosen for...
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PMID: 21751810
PDF is available here.
Abstract
We show in the Hodgkin & Huxley model of the action potential and in experiments on squid giant axons that: 1) spike generation in a neuron can be highly discriminatory for stimulus shape and 2) the optimal stimulus shape is dependent upon inputs to the neuron. We show how polarity and time course o...
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PMID: 21760759
PDF is available here.
Abstract
Our results confirm the importance of pH and related geochemical factors in fine-tuning acidophilic microbial community structure and function at the species and strain level, and demonstrate the broad utility of proteomics in laboratory community studies....
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PMID: 21228889
PDF is available here.
Abstract
Two feeding ratios, 3:1 (RUN I) and 2:1 (RUN II), were experimented to investigate their effect on removal of nitrogen, phosphorus, organic matter, and on the trends of oxidization-reduction potential (ORP) and pH in sequencing batch reactors (SBR) with dual anoxic feedings of swine wastewater. Resul...
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PMID: 21790083
PDF is available here.
Abstract
Moxifloxacin and lomefloxacin are fluoroquinolone antibiotics used in treating urinary and respiratory tract infections. Fluoroquinolones are known to have interactions with drugs that are active in gastro intestinal tract. Being moxifloxacin and lomefloxacin fluoroquinolones the interaction study of...
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PMID: 21715267
PDF is available here.
Abstract
Organic wastes have been reported to reduce saturation of the exchange complex by Al in Al-rich acid soils. For 3 years, the main soil fertility properties were studied in plots sown with mixed pasture species. These plots were fertilized with cattle slurry, dairy sludge (DS), or granulated broiler l...
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PMID: 21850833
PDF is available here.
Abstract
To assess the effects of three types of Mg and P salt mixtures (potassium phosphate [K3PO4]/magnesium sulfate [MgSO4], potassium dihydrogen phosphate [K2HPO4]/MgSO4, KH2PO4/MgSO4) on the conservation of N and the biodegradation of organic materials in an aerobic food waste composting process, batch e...
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PMID: 21850832
PDF is available here.
Abstract
We developed a zwitterionic amino acid tethered amphiphilic molecule 1, which gave rise to a remarkably stiff hydrogel comparable with polymer-based agarose gel, retaining reversible thermal-responsive properties. In this study, we describe that rational accumulation of multiple and orthogonal nonco...
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PMID: 21721133
PDF is available here.
Abstract
We applied multilayered polyelectrolyte assemblies on nanoparticles to create viable systemic delivery systems. Focusing on tumor-specific delivery, LbL nanoparticles that exhibit a pH-sensitive outer stealth layer are demonstrated to target and be retained in hypoxic tumor regions. The neutral laye...
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PMID: 21513353
PDF is available here.
Abstract
We applied multilayered polyelectrolyte assemblies on nanoparticles to create viable systemic delivery systems. Focusing on tumor-specific delivery, LbL nanoparticles that exhibit a pH-sensitive outer stealth layer are demonstrated to target and be retained in hypoxic tumor regions. The neutral laye...
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PMID: 21513353
PDF is available here.
Abstract
A facile, template-free, and environmentally friendly hydrothermal strategy was explored for the controllable synthesis of α-Fe(2) O(3) nanostructures in HEPES solution (HEPES=2-[4-(2-hydroxyethyl)-1-piperazinyl]ethanesulfonic acid). The effects of experimental parameters including...
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PMID: 21661117
PDF is available here.
Abstract
Abstract In nature the foodborne pathogen Listeria monocytogenes lives as a saprophyte where it can contaminate preharvest produce. This environment can present many stresses such as ultraviolet light, variations in temperature and humidity, and oxidative stress from growing plant ma...
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PMID: 21381923
PDF is available here.
Abstract
The pleiotropic functions of disaccharide trehalose in the biology of nematodes and its absence from mammalian cells suggest that its biosynthesis may provide a useful target for developing novel nematicidal drugs. The trehalose-6-phosphate phosphatase (TPP), one of the enzymes of trehalose metabolis...
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PMID: 21658361
PDF is available here.
Abstract
The identification and characterization of filamentous bacteria and their association with specific plant operating conditions and influent characteristics has been hampered because of morphological variations and differences between process configurations. A study was conducted to isolate and charac...
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PMID: 21751711
PDF is available here.
Abstract
The shelf life of fresh Italian pork sausages packed in modified atmosphere was studied. Samples were packed using different levels of oxygen (high and low) with different levels of carbon dioxide (high-low) in the atmospheres headspace and were stored at 4 °C for 9 days. Microbial,...
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PMID: 21693619
PDF is available here.
Abstract
In Bangladesh, arsenic contamination of groundwater, microbial contamination of surface water and seasonally variable rainfall make reliable access to acceptable quality drinking water a challenge. Arsenic-iron removal plants (AIRPs) are a relatively inexpensive way of removing arsenic from groundwat...
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PMID: 21942197
PDF is available here.
Abstract
We evaluated the ability of UNICEF-designed pot-chlorinators to achieve recommended free residual chlorine (FRC) levels in well water in Bissau, Guinea-Bissau, during a cholera outbreak. Thirty wells were randomly selected from six neighbourhoods. Pot-chlorinators--perforated plastic bottles filled w...
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PMID: 21942203
PDF is available here.
Abstract
To evaluate the degree of penetration of an ammonium hexafluorosilicate [SiF: (NH4)2SiF6] solution containing various antibacterial agents into dentin and the depth of dentin tubule occlusion by the precipitate.
Various antibacterial SiF solutions were prepared with t...
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PMID: 21874933
PDF is available here.
Abstract
To assess whether pastes containing casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and calcium sodium phosphosilicate (CSP) protect acid softened enamel against further erosive episodes.
Enamel slabs of bovine teeth with preformed erosion-like lesions wer...
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PMID: 21874937
PDF is available here.
Abstract
All treated dentin sections showed occluded dentin tubules; with the group A3 showing the highest percent of occluded dentin tubules. The precipitates in the dentin tubules treated with A3 remained while those treated with OX/Ca or OX/P dissolved after exposure to an acidic buffer....
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PMID: 21874938
PDF is available here.
Abstract
To investigate the influence of calcium phosphate enhanced home whitening agents on human enamel and dentin surface microhardness and ultramorphology.
Five intact molars crowns were used for ultrastructural analysis and five for microhardness test. Each resulting coro...
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PMID: 21874930
PDF is available here.
Abstract
We prepared a liposomal hydrogel of adenosylcobalamin (AdCbl), a vitamin B12 derivative, and investigated possible beneficial effects of AdCbl on atopic dermatitis using an NC/Nga murine atopic dermatitis model. AdCbl was loaded into liposomes prepared by a thin film hydration method using a pH grad...
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PMID: 21699082
PDF is available here.
Abstract
A delivery system which provides bimodal pH dependent release of poorly water soluble carvedilol in gastric and intestinal environment was designed. Preparation of solid dispersion with porous silica ensured a significantly higher dissolution rate of carvedilol in acidic and alkaline media in compari...
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PMID: 21699090
PDF is available here.
Abstract
The paper presents the results of viscosity determinations on aqueous solutions of different mammalian serum albumins at a wide range of concentrations and at temperatures ranging from 278 K to 318 K. On the basis of these measurements and a modified Arrhenius equation, the functiona...
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PMID: 21613666
PDF is available here.
Abstract
We studied how dimethyloxallyl glycine (DMOG), an activator and stabilizer of the hypoxia-inducible factor (HIF)-1α, could affect expression of the NCX1 in HEK 293 cell line. We also tried to determine whether this activation can result in the induction of apoptosis in HEK 293 cells. We have found...
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PMID: 21613675
PDF is available here.
Abstract
We investigated hemocyte adhesion to organs mediating the selectin-selectin ligands during the feeding period and the larval-larval molting period using the lectin staining method, sugar chain digestion test with glycoside hydrolases, and the hemocyte adhesion inhibition test using monosaccharides....
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PMID: 21627452
PDF is available here.
Abstract
We assessed ΔG'(ATP) hydrolysis, cytosolic [ADP], and the rate of phosphocreatine recovery using Phosphorus Magnetic Resonance Spectroscopy in the calf muscle of a group of patients affected by glycogen myo-phosphorylase deficiency (McArdle disease). The goal was to ascertain whether and to what ex...
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PMID: 21722623
PDF is available here.
Abstract
Porous silicon nanoparticles (PSiNPs) were synthesized by a silver-assisted electroless chemical etching of silicon nanowires generated on a silicon wafer. The rod-shaped particles (200-400 nm long and 100-200 nm in diameter) were derivatized with a cyclodextrin based nanovalve that...
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PMID: 21595466
PDF is available here.
Abstract
We used two dimensional gel electrophoresis (2-DE) over a narrow pH 3-5.6 range since this lies outside the range of highly abundant albumin, transferrin and immunoglobulins. In addition, we used in-solution isoelectric focusing followed by SDS-PAGE to find biomarkers in hepatitis C induced liver ci...
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PMID: 21410221
PDF is available here.
Abstract
The culture of Chinese hamster ovary (CHO) cells to produce monoclonal antibodies (MAb) requires accurate measurement and control of pH. Unwanted pH drifts in cell culture can adversely affect process performance, product quality, and product yield. To measure and control pH througho...
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PMID: 21567988
PDF is available here.
Abstract
We have recently reported a kinetic and mechanistic study on oxidative dissolution of silver nanoparticles (AgNPs) by H(2) O(2) . In the present study, the parameters that govern the dissolution of AgNPs by O(2) were revealed by using UV/Vis spectrophotometry. Under the same reaction conditions (Tri...
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PMID: 21608134
PDF is available here.
Abstract
The movement of the small ribosomal subunit (30S) relative to the large ribosomal subunit (50S) during translation is widely known, but many molecular details and roles of rRNA and proteins in this process are still undefined, especially in solution models. The functional relationship of modified nuc...
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PMID: 21557607
PDF is available here.
Abstract
Pyrazine-labeled multicompartment nanostructures are shown to exhibit enhanced pH-responsive blue-shifted fluorescence emission intensities compared to their simpler core-shell spherical analogs. An amphiphilic linear triblock terpolymer of ethylene oxide, N-acryloxysuccinimide, and styrene, PEO(45)-...
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PMID: 21574617
PDF is available here.
Abstract
We study ZnO in ethanol for which the influence of particle size and reactant ratio as well as surface coverage on colloidal stability in dependence of the purification progress was investigated. The results revealed that the well-known ζ-potential determines not only the colloidal stability but al...
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PMID: 21545143
PDF is available here.
Abstract
We show that (71) Ga NMR is a useful tool to rapidly detect the presence of gallate in aqueous solutions of Ga complexes and to follow the purification steps of the Ga complex solutions. Copyright © 2011 John Wiley & Sons, Ltd.
Copyright © 2011 John Wiley & Sons, Ltd....
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PMID: 21698774
PDF is available here.
Abstract
We analyzed the effect of CaCl(2), NaCl and NH(4)NO(3) salts in combination with the pH and nucleotide cofactor effect on the ssDNA-binding activity of RecA. The studies revealed that, in addition to the inhibitory effect, these salts exert also a stimulatory effect on RecA. These effects occur only...
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PMID: 21615990
PDF is available here.
Abstract
To study oral health in young adults with long-term, controlled asthma.
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PMID: 21231815
PDF is available here.
Abstract
Proton-coupled electron-transfer (PCET) is a mechanism of great importance in protein electron transfer and enzyme catalysis, and the involvement of aromatic amino acids in this process is of much interest. The DNA repair enzyme photolyase provides a natural system that allows for the study of PCET u...
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PMID: 21534528
PDF is available here.
Abstract
A sorption process for the removal of phosphate was evaluated under various conditions using a filter bed packed with giant reed (GR) based adsorbent. FTIR spectrum measurement validated the existence of grafted amine groups in the adsorbent and Raman spectrum displayed the characteristic peaks of di...
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PMID: 21094604
PDF is available here.