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### Articles on Ventilation-Perfusion Ratio

1. 18F-FDG uptake rate is a biomarker of eosinophilic inflammation and airway response in asthma.

crossref 52(11):1713-20 1 Nov 2011 PMID 21990575

We found systematic reductions in regional $$\stackrel{\cdot }{Q}$$, $$s{\stackrel{\cdot }{V}}_{A}$$, and Fgas and increased ω in all subjects. The ratio of eosinophil count (allergen to diluent) was linearly related (R(2) = 0.9917, P < 0.001) to the ratio of K(i). CONCLUSION: Regional K(i) meas...
2. Respiratory physiology at altitude.
The changes in respiratory physiology that occur with increasing altitude are driven by the fall in the partial pressure of oxygen that occurs with decreasing barometric pressure. At altitude, respiratory system changes occur which impact on each step of the oxygen cascade that occurs within the body...
3. A review of electrocardiography in pulmonary embolism: recognizing pulmonary embolus masquerading as ST-elevation myocardial infarction.
We review the differential diagnosis of ST elevation and the assorted spectrum of ECG changes seen in PE....
4. Inhalation anesthesia increases V/Q regional heterogeneity during spontaneous breathing in healthy subjects.
We hypothesized that inhalation anesthesia influences the intrapulmonary distribution of ventilation (V) and perfusion (Q), leading to less advantageous V/Q matching. Ten healthy volunteers were studied in supine position on two separate occasions, once awake and once during mild anesthesia (sevoflu...
5. Recombinant angiotensin-converting enzyme 2 improves pulmonary blood flow and oxygenation in lipopolysaccharide-induced lung injury in pigle...
Angiotensin-converting enzyme 2 attenuates arterial hypoxemia, pulmonary hypertension, and redistribution of pulmonary blood flow in a piglet model of acute respiratory distress syndrome, and may be a promising substance for clinical use....
6. A mathematical model of pulmonary gas exchange under inflammatory stress
We first derived a partial differential equations model of gas exchange on a small physiological unit of the lung ( approximately 25 alveoli), which we refer to as a respiratory unit (RU). We next developed a simple model of the acute inflammatory response and implemented its effects within a RU, cr...
7. Can plasma D-dimer predict the result of a ventilation-perfusion scan?
We retrospectively looked at 840 patients in whom both ventilation-perfusion scan and D-dimer assay were performed within 48 h. The negative predictive value of a negative D-dimer assay was 96% for emergency admissions and 98% for inpatients. We present the cases of two patients with negative D-dime...
8. Volumetric capnography: in the diagnostic work-up of chronic thromboembolic disease.
We report the case of a patient whose diagnosis of PE was made via pulmonary arteriography. The clinical pretest revealed a moderate probability of the patient having PE, and the DD result was negative; however, the VCap associated with arterial blood gases result was positive. The patient underwent...
9. N-terminal natriuretic peptide and ventilation-perfusion lung scan in sickle cell disease and thalassemia patients with pulmonary hypertensi...
The aim of this study was to determine the prevalence of pulmonary hypertension (PH) in sickle cell disease and thalassemia patients in relation to clinical and laboratory parameters of hemolysis and hemosidersosis, as well as plasma N-terminal pro-brain natriuretic peptide (NT-pro-BNP). The study a...
10. Assessment of resting perfusion defect in patients with acute myocardial infarction: comparison of myocardial contrast echocardiography with...
Myocardial contrast echocardiography correlates very well with CE-MRI in the assessment of myocardial perfusion after PCI in AMI. Contrast-enhanced MRI is accurate technique for assessing the infarct zone. Identification by CE-MRI of transmural necrosis was associated with more impaired left ventric...