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Complex Mixtures (15)
Articles on Complex Mixtures
Biogeographical analysis of chemical co-occurrence data to identify priorities for mixtures research.
We investigate methods from the field of biogeography, originally developed to study avian species co-occurrence patterns, and adapt these approaches to examine chemical co-occurrence. These methods were applied to a national survey of pesticide residues in 168 child care centers from across the cou...
Cigarette smoking and inflammation: cellular and molecular mechanisms.
Cigarette smoke (CS) causes considerable morbidity and mortality by inducing cancer, chronic lung and vascular diseases, and oral disease. Despite the well-recognized risks associated with smoking, the habit remains unacceptably prevalent. Several toxins present in CS have immunomodu...
Functional proteomics: application of mass spectrometry to the study of enzymology in complex mixtures.
This review covers recent developments in mass spectrometry-based applications dealing with functional proteomics with special emphasis on enzymology. The introduction of mass spectrometry into this research field has led to an enormous increase in knowledge in recent years. A major...
Preliminary studies for a new antibiotic from the marine mollusk Melo melo (Lightfoot, 1786).
To search for new bioactive compounds from marine mollusks Melo melo (M. melo). Preliminary work for bioactive compound was identified by using disc diffusion methods against human pathogens. Further analyses of compound were done by using TLC, SDS-PAGE. And also esti...
Inhibition of Transforming Growth Factor @b Worsens Elastin Degradation in a Murine Model of Kawasaki Disease
We hypothesized that, in contrast to the benefit observed in aneurysms forming in those with Marfan syndrome, inhibition of TGF-β would worsen inflammatory-induced coronary artery lesions. By using a murine model of KD in which injection of Lactobacillus casei wall extract (LCWE) induces coronary a...
In vitro antiplasmodial activity of crude extracts from Togolese medicinal plants.
To investigate the antimalarial effect of a few plants in Togo folk medicine. After ethnobotanical survey, Opilia celtidifolia, Pavetta corymbosa (P. corymbosa) and Tamarindus indica (T. indica) were selected for screening. In vitro antimalarial tests were performed o...
Antinociceptive and anti-inflammatory activities of crude extracts of Ipomoea involucrata leaves in mice and rats.
These results support the claims on the traditional use of the of Ipomoea involucrata leaves in the treatment of toothache, rheumatic pains and other inflammatory conditions. Studies on the isolation and structural elucidation of the active principle are still needed being carried out....
Methods and options for the heterologous production of complex natural products.
This review will detail the motivations, experimental approaches, and growing list of successful cases associated with the heterologous production of complex natural products.
[Pharmacological modulation of nitrogen oxide system in experimental chronic alcoholic intoxication in rats].
The modeling of chronic alcohol intoxication for 30 days in rats leads to an increase in the level of free metabolites of nitrogen oxide and NO-synthase with simultaneous decrease in the levels of L-arginine, catalase, and superoxide dismutase. The subsequent 14-day treatment with ne...
Preparation of extracts from yeast.
Because yeast is exceptionally well suited to genetic analysis, both classical and molecular, it is an attractive system for expressing recombinant animal proteins for purification purposes. Methods available for lysing yeast cells include autolysis, pressure cells (e.g., French pres...