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Emulsions (0):
Recent article
Emulsions
Abstract
The aim of this study was to evaluate the effects of newly formulated topical cream of Calendula officinalis extract on the mechanical parameters of the skin by using the cutometer. The Cutometer 580 MPA is a device that is designed to measure the mechanical properties of the skin in response to the...
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PMID: 21928714
PDF is available here.
PDF is available here.
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Abstract
Multifunctional lipid nanoemulsions have shown to combine several advantages e.g. tissue targeting, cell targeting, imaging analysis, barrier permeability enhancement, and therapeutic purposes. Depending on the choice of lipid composition, surfactants and additional surface modifiers...
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PMID: 21812320
PDF is available here.
PDF is available here.
Abstract
These results indicated that solvent emulsification evaporation is a simple, easy, available and effective method for preparing SYR-SLN....
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PMID: 21699077
PDF is available here.
PDF is available here.
Abstract
Physicochemical properties of the novel photosensitizer meso-tetraphenyl chlorin disulphonate (TPCS2a) and the chemically related meso-tetraphenyl porphyrin disulphonate (TPPS2a) were investigated in aqueous solutions as part of pharmaceutical preformulation. Inflection points were calculated to be 3...
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PMID: 21699065
PDF is available here.
PDF is available here.
Abstract
PX-18 and PX-13 are secretory phospholipase A2-IIA (sPLA2-IIA) inhibitors. An increased expression of sPLA2 in psoriatic skin has been reported. The selective inhibition of this enzyme is a new therapeutic approach. For dermal application PX-18 and PX-13 have been loaded to Nanostructured lipid carri...
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PMID: 21699069
PDF is available here.
PDF is available here.
Abstract
Gene silencing by RNA interference is a rapidly growing therapeutic area for managing diseases. Despite research advances in this direction, the poor cellular uptake of synthetic small interfering RNAs is a major impediment to their clinical applications. Polymer and lipid-based systems are attractiv...
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PMID: 21699063
PDF is available here.
PDF is available here.
Abstract
Silymarin is a complex mixture of four flavonolignan isomers (silybin, isosilybin, silydianin and silychristin) obtained from 'milk thistle' (Silybum marianum). This plant compound is used almost exclusively for hepatoprotection. Because of its low and poor oral bioavailability, silymarin was formula...
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PMID: 21656362
PDF is available here.
PDF is available here.
Abstract
We investigated the role of positively and negatively charged amino acids within the 89-99 region of apolipoprotein A-I (apoA-I), which are highly conserved in mammals, on plasma lipid homeostasis and the biogenesis of HDL. We previously showed that deletion of the 89-99 region of apoA-I increased p...
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PMID: 21504968
PDF is available here.
PDF is available here.
Abstract
The objective of the present study was to determine the intestinal absorption of sulpiride incorporated into SMEDDS by means of single-pass intestinal perfusion method (SPIP) in rat and to compare the effective permeability coefficient obtained with that of drug solution and micellar...
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PMID: 21454158
PDF is available here.
PDF is available here.
Abstract
The objective of the present investigation was to prepare mucoadhesive microspheres of ketorolac for nasal administration by means of a solvent evaporation technique using carbopol (CP), polycarbophil (PL) and chitosan (CS) as mucoadhesive polymers. The prepared microspheres were cha...
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PMID: 21612151
PDF is available here.
PDF is available here.
Abstract
These results indicate that the combination of a microemulsion and a phospholipid complex represents an effective vehicle for topical delivery of OMT....
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PMID: 21544720
PDF is available here.
PDF is available here.
Abstract
Betulinic acid (3beta, hydroxy-lup-20(29)-en-28-oic acid, BA), a pentacyclic triterpenoid, is derived from a widely distributed natural anticancer compound betulin. It has selective anticancer activity against several tumor cells, and recently it was shown that it also possess anti-a...
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PMID: 21702370
PDF is available here.
PDF is available here.
Abstract
Hydroxyapatite and hybrid gelatine/hydroxyapatite microspheres were obtained through a water in oil emulsion of a calcium phosphate cement (CPC). The setting reaction of the CPC, in this case the hydrolysis of α-tricalcium phosphate, was responsible for the consolidation of the micr...
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PMID: 21290594
PDF is available here.
PDF is available here.
Abstract
Functional properties were identified for the total globulin (TG), 7S and 11S fractions of Lima bean (Phaseolus lunatus L.) seeds. The 11S component accounted for 58.3% of TGs and the 7S for 41.7%. Solubility was higher in the 7S fraction, especially at alkaline pHs. Water-holding capacity was simila...
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PMID: 21421671
PDF is available here.
PDF is available here.
Abstract
A tomato flavor enhancer, 2-isobutylthiazole (IBT), was added (5 mg/kg) to dressings emulsified with either a whey protein concentrate-80 (WPC-80), a WPC-80 hydrolysate or β-lactoglobulin at high pressure (70 MPa) at either 20 or 75 °C. The short (2-4 min), high-temperature treatment left the prote...
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PMID: 21436234
PDF is available here.
PDF is available here.
Abstract
The polar paradox is a theory that illustrates the paradoxical behavior of antioxidants in different media and rationalizes the fact that polar antioxidants are more effective in less polar media, such as bulk oils, while nonpolar antioxidants are more effective in relatively more polar media, such a...
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PMID: 21375307
PDF is available here.
PDF is available here.
Abstract
We report the results of an experimental study of the microstructure of dispersions of Carbopol ETD 2050, a model yield-stress fluid. Using two different light scattering instruments, measurements were made over three decades in scattering wave vector, from 0.02 to 25 μm^{-1}. These measurements re...
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PMID: 21517498
PDF is available here.
PDF is available here.
Abstract
Due to the eye's specific anatomical and physiological conformation, the treatment of eye diseases is a real challenge for pharmaceutical therapy. The presence of efficient protective barriers (i.e., the conjunctival and corneal membranes) and protective mechanisms (i.e., blinking and nasolachrymal d...
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PMID: 21440104
PDF is available here.
PDF is available here.
Abstract
A study on the phenomenon of clouding and the applications of cloud point technology has been thoroughly discussed. The phase behaviour of clouding and various methods adopted for the determination of cloud point of various surfactant systems have been elucidated. The systems containing anionic, cati...
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PMID: 21296314
PDF is available here.
PDF is available here.
Abstract
The objective of the present study was to develop a nanocarrier based formulation of nadifloxacin and to investigate its in vitro antimicrobial effect against Propionibacterium acnes. Nanocarrier based microemulsion formulations were prepared by aqueous titration method, using oleic...
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PMID: 21434572
PDF is available here.
PDF is available here.
Abstract
We examined whether cationic submicron emulsions (CSEs) can efficiently deliver hydroxycamptothecin (HCPT) into MDR cells (SGC7901/VCR cells) via electrostatic-mediated endocytosis, thus overcoming MDR. We prepared HCPT-CSEs and rhodamine-123-CSEs (RH-123-CSEs), and examined the in vitro cytotoxic a...
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PMID: 21434576
PDF is available here.
PDF is available here.
Ugeskrift for laeger (173)2 2011
Abstract
OBJECTIVE: To draw attention to the use of intravenous lipids in the treatment of cardiac arrests caused by overdosage of lipophilic drugs. Case reports and animal studies have shown beneficial use of lipids in severe intoxication. The literature is reviewed. CONCLUSION: Lipids have a place in the t...
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PMID: 21219843
PDF is available here.
PDF is available here.
Abstract
Alginate based mineral oil entrapped emulsion gel (MOEG) buoyant beads of domperidone were prepared by emulsion gelation technique. The prepared beads were evaluated for particle size, surface morphology, buoyancy, actual drug content and entrapment efficiency. Effect of different oils (castor oil, o...
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PMID: 21485710
PDF is available here.
PDF is available here.
Abstract
We show by (19)F MR spectroscopy (MRS) that the efficiency in labeling cells of the murine immune system (dendritic cells) by perfluoro-15-crown-5-ether (PFCE) particles increases with increasing particle size (560365245130 nm). Dendritic cells (DC) are professional antigen presenting cells and with...
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PMID: 21811551
PDF is available here.
PDF is available here.
Abstract
These results indicate that the limonene microemulsion system is a promising tool for the percutaneous delivery of curcumin.
Copyright © 2010 Elsevier B.V. All rights reserved....
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PMID: 20828994
PDF is available here.
PDF is available here.
Abstract
This paper reports a microfluidic synthesis of biopolymer microparticles aiming at smart swelling. Monodisperse aqueous emulsion droplets comprising biopolymer and its cross-linking agent were formed in mineral oil and solidified in the winding microfluidic channels by in situ chaotic mixing, which...
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PMID: 20833004
PDF is available here.
PDF is available here.
Abstract
The formulation of water dispersible nanopermethrin was investigated for its larvicidal property. Nanopermethrin was prepared using solvent evaporation of oil in water microemulsion, which was obtained by mixing an organic and aqueous phase. The mean particle size of nanodispersion in water was 151...
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PMID: 20833431
PDF is available here.
PDF is available here.
Chemical Communications (46)38 2010
Abstract
Millimetre-sized mesoporous carbon spheres (MMCSs) with smooth surface and penetrating mesoporous channels have been successfully prepared by an emulsion-EISA technique, and are found to be a much better bilirubin adsorbent than commercial activated carbon spheres. Hemolysis and coagulation assays o...
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PMID: 20725682
PDF is available here.
PDF is available here.
Abstract
To evaluate the safety, tolerability and immunogenicity of an AS03(B)/oil-in-water emulsion-adjuvanted (AS03(B)) split-virion versus non-adjuvanted whole-virion H1N1 influenza vaccine in UK children aged 6 months to 12 years.
Multicentre, randomised, head-to-head, open-label trial.
Five UK sites (Ox...
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PMID: 20923610
PDF is available here.
PDF is available here.
Abstract
To investigate the mechanisms of the oil-in-oil nanoemulsions transport through the gastrointestinal tract and the transport efficiency changed with its different particle size in the lymphatic channels.
The behavior of nanoemulsions in vivo and their absorption via lymph after oral administration w...
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PMID: 21246816
PDF is available here.
PDF is available here.
Abstract
To research the microemulsion preparation of Ganoderma lucidum polysaccharides and triterpenes and investigate its properities. Evaluate the effects of polysaccharides and triterpenes microemulsions against transplant tumor growth.
The microemulsion formula was optimized by constructing the pseudo-t...
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PMID: 21246817
PDF is available here.
PDF is available here.
Abstract
To investigate the cellular uptake and elimination process of a lipophilic drug loaded in different nanocarriers, emulsions, liposomes and poly (DL-lactide-co-glycolide) (PLGA) nanoparticles loaded with a model drug, coumarin 6, were prepared and their transportation in HeLa cells compared. After 4...
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PMID: 21105575
PDF is available here.
PDF is available here.
Food and Chemical Toxicology (48)10 2010
Abstract
The toxicity of sodium stearoyl lactylate (SSL) was examined in Wistar rats fed diets containing 0, 1.25, 2.5, and 5% SSL for one year, equivalent to mean daily intakes of 558, 1115, and 2214 mg/kg/day in males and 670, 1339, and 2641 mg/kg/day in females, respectively. SSL was well tolerated at the...
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PMID: 20600527
PDF is available here.
PDF is available here.
Abstract
The main objective of the study was to investigate the efficacy of microemulsion (ME) to facilitate bioavailability of puerarin (PUE) after oral and nasal administration. The pseudo-ternary phase diagrams were constructed to screen the ME components and optimize the ME formulation. The optimized form...
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PMID: 20862776
PDF is available here.
PDF is available here.
Optics Express (18)18 2010
Abstract
We present a new method to make liquid lenses. It is based on the microfluidics method and involves the preparation of emulsions one drop at a time. Tests of lenses by image formation are presented. Experimental results are compared with results of an optical design program. We also present a new ty...
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PMID: 20940763
PDF is available here.
PDF is available here.
AAPS PharmSciTech (11)3 2010
Abstract
Parasitic diseases are of immense global significance as around 30% of world's population experiences parasitic infections. Among these, malaria is the most life-threatening disease. Various routes of administration have been explored for delivering antimalarial actives. The present...
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PMID: 20661674
PDF is available here.
PDF is available here.
Atherosclerosis (212)1 2010
Abstract
We showed that training increases LDL plasma clearance, as tested by an artificial LDL-like nanoemulsion method, presumably by increasing LDL receptor activity. In this study, we investigated whether training could also improve LDL clearance in hypercholesterolemic subjects (HCh) that are exposed to...
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PMID: 20627247
PDF is available here.
PDF is available here.
Journal of Chromatography A (1217)34 2010
Abstract
Eight l-tartrates and a d-tartrate with different alcohol moieties were used as chiral oils to prepare chiral microemulsions, which were utilized in conjunction with borate buffer to separate the enantiomers of beta-blockers or structurally related compounds by the chiral microemulsion electrokineti...
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PMID: 20638068
PDF is available here.
PDF is available here.
Abstract
Abstract
We report the use of bovine serum albumin (BSA) as an osmotic agent in order to control the porous structure of poly(D,L-lactide-co-glycolide) (PLGA) microspheres prepared by a double emulsion method. BSA was useful to induce osmosis between internal and external water phases during the double emuls...
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PMID: 20553775
PDF is available here.
PDF is available here.
Abstract
We have developed a robust technique to fabricate monodispersed solid and porous ceramic particles and capsules from single and double emulsion drops composed of silsesquioxane preceramic polymer. A microcapillary microfluidic device was used to generate the monodispersed drops. In this device, two...
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PMID: 20484226
PDF is available here.
PDF is available here.
Abstract
The purpose of this study was to evaluate the potential of new carboxylated multi-block copolymer of lactic acid and ethylene glycol (EL14) for nanoparticle (NP) formation and their ability to deliver high molecular weight hydrophobic drug--cyclosporine A (CsA). CsA-loaded EL14 NPs were compared wit...
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PMID: 20504806
PDF is available here.
PDF is available here.
Abstract
To compare the acute toxicity and the pharmacological effect of Huoxiang Zhengqi microemulsion and Huoxiang Zhengqi tincture.
The acute toxicities of Huoxiang Zhengqi microemulsion and Huoxiang Zhengqi tincture were observed by the test of maximum dose in mice and the antidiarrheal effects of them w...
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PMID: 20931856
PDF is available here.
PDF is available here.
Abstract
The purpose of the present study was to study the impact of free fatty acid and monoglyceride level and ratio on the nanostructural composition and solubilizing capacity of media simulating fed state intestinal fluids (SIFs). SIFs, without or with oleic acid/monoolein (OA/MO) in rati...
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PMID: 20564382
PDF is available here.
PDF is available here.
Abstract
Compared with traditional macroemulsion propofol formulations currently in clinical use, microemulsion formulations of this common intravenous anesthetic may offer advantages. The pharmacokinetics and coagulation effects as assessed by thromboelastography of these formulations were characterized in...
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PMID: 20578214
PDF is available here.
PDF is available here.
Abstract
Our data suggest that the new lipid tear substitute can be used to treat clinical signs of dry eye and that the combined administration with hyaluronate can decrease the lag time before the effect, when the evaporative and the aqueous-deficient components are present....
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PMID: 20489574
PDF is available here.
PDF is available here.
Meat Science (85)3 2010
Abstract
The effects of freeze-thaw cycles (FT, 0, 1, 3 and 5 times) on protein functional properties of porcine longissimus muscle were investigated. FT increased gapping between muscle fibres and tore muscle fiber bundles. Myofibrillar protein (MP) isolated from FT muscle showed an increased hydrophobicity...
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PMID: 20416818
PDF is available here.
PDF is available here.
Meat Science (85)3 2010
Abstract
The influence of protein oxidation, as measured by the dinitrophenylhydrazine (DNPH) method, on colour and texture changes during chill storage (2 degrees C, 12days) of cooked burger patties was studied. Extracts from arbutus-berries (Arbutus unedoL., AU), common hawthorns (Crataegus monogynaL., CM)...
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PMID: 20416800
PDF is available here.
PDF is available here.
Abstract
The aim of this work is to devise an efficient enzymatic process for the production of linear alkyl esters in aqueous miniemulsion systems. The esterification reactions of linear alcohols and carboxylic acids were performed with three different enzymes, commercial Amano lipase PS fro...
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PMID: 20503297
PDF is available here.
PDF is available here.
Electrophoresis (31)13 2010
Abstract
Seven food grade antioxidants were resolved by microemulsion electrokinetic chromatography. The antioxidants included propyl gallate, octyl gallate, dodecyl gallate, butylated hydroxyanisole, butylated hydroxytoluene, tert-butylhydroquinone and alpha-tocopherol. They were resolved in...
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PMID: 20533329
PDF is available here.
PDF is available here.
Electrophoresis (31)13 2010
Abstract
Seven food grade antioxidants were resolved by microemulsion electrokinetic chromatography. The antioxidants included propyl gallate, octyl gallate, dodecyl gallate, butylated hydroxyanisole, butylated hydroxytoluene, tert-butylhydroquinone and alpha-tocopherol. They were resolved in...
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PMID: 20533329
PDF is available here.
PDF is available here.
Electrophoresis (31)13 2010
Abstract
Seven food grade antioxidants were resolved by microemulsion electrokinetic chromatography. The antioxidants included propyl gallate, octyl gallate, dodecyl gallate, butylated hydroxyanisole, butylated hydroxytoluene, tert-butylhydroquinone and alpha-tocopherol. They were resolved in...
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PMID: 20533329
PDF is available here.
PDF is available here.
Electrophoresis (31)13 2010
Abstract
Seven food grade antioxidants were resolved by microemulsion electrokinetic chromatography. The antioxidants included propyl gallate, octyl gallate, dodecyl gallate, butylated hydroxyanisole, butylated hydroxytoluene, tert-butylhydroquinone and alpha-tocopherol. They were resolved in...
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PMID: 20533329
PDF is available here.
PDF is available here.
Electrophoresis (31)13 2010
Abstract
Seven food grade antioxidants were resolved by microemulsion electrokinetic chromatography. The antioxidants included propyl gallate, octyl gallate, dodecyl gallate, butylated hydroxyanisole, butylated hydroxytoluene, tert-butylhydroquinone and alpha-tocopherol. They were resolved in...
|
PMID: 20533329
PDF is available here.
PDF is available here.
Electrophoresis (31)13 2010
Abstract
Seven food grade antioxidants were resolved by microemulsion electrokinetic chromatography. The antioxidants included propyl gallate, octyl gallate, dodecyl gallate, butylated hydroxyanisole, butylated hydroxytoluene, tert-butylhydroquinone and alpha-tocopherol. They were resolved in...
|
PMID: 20533329
PDF is available here.
PDF is available here.
Electrophoresis (31)13 2010
Abstract
Seven food grade antioxidants were resolved by microemulsion electrokinetic chromatography. The antioxidants included propyl gallate, octyl gallate, dodecyl gallate, butylated hydroxyanisole, butylated hydroxytoluene, tert-butylhydroquinone and alpha-tocopherol. They were resolved in...
|
PMID: 20533329
PDF is available here.
PDF is available here.
Electrophoresis (31)13 2010
Abstract
Seven food grade antioxidants were resolved by microemulsion electrokinetic chromatography. The antioxidants included propyl gallate, octyl gallate, dodecyl gallate, butylated hydroxyanisole, butylated hydroxytoluene, tert-butylhydroquinone and alpha-tocopherol. They were resolved in...
|
PMID: 20533329
PDF is available here.
PDF is available here.
Electrophoresis (31)13 2010
Abstract
Seven food grade antioxidants were resolved by microemulsion electrokinetic chromatography. The antioxidants included propyl gallate, octyl gallate, dodecyl gallate, butylated hydroxyanisole, butylated hydroxytoluene, tert-butylhydroquinone and alpha-tocopherol. They were resolved in...
|
PMID: 20533329
PDF is available here.
PDF is available here.
Electrophoresis (31)13 2010
Abstract
Seven food grade antioxidants were resolved by microemulsion electrokinetic chromatography. The antioxidants included propyl gallate, octyl gallate, dodecyl gallate, butylated hydroxyanisole, butylated hydroxytoluene, tert-butylhydroquinone and alpha-tocopherol. They were resolved in...
|
PMID: 20533329
PDF is available here.
PDF is available here.
Electrophoresis (31)13 2010
Abstract
Seven food grade antioxidants were resolved by microemulsion electrokinetic chromatography. The antioxidants included propyl gallate, octyl gallate, dodecyl gallate, butylated hydroxyanisole, butylated hydroxytoluene, tert-butylhydroquinone and alpha-tocopherol. They were resolved in...
|
PMID: 20533329
PDF is available here.
PDF is available here.