Abstract
We measured the effect of variations in scaffold stiffness on the expression of extracellular matrix molecules specific to the NP (proteoglycans and collagen) by native NP cells. We prepared sample discs of different concentrations of alginate (1%-6%) by two different methods, diffusion and in situ...
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PMID: 21783128
PDF is available here.
Abstract
Evaluation of antimicrobial activity of L-cysteine silver gel against various species of pathogenic and opportunistic microorganisms.
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PMID: 21913399
PDF is available here.
Abstract
Soft-tissue injuries are commonly treated with ice or menthol gels. Few studies have compared the effects of these treatments on blood flow and muscle strength.
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PMID: 21828387
PDF is available here.
Abstract
Azelaic acid (AzA) gel 15% is approved by the US Food and Drug Administration (FDA) for the treatment of papulopustular rosacea (PPR). Its efficacy and safety as monotherapy have been demonstrated. Release of active drug from the gel formulation is superior to the cream. The combination of AzA gel 15...
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PMID: 21916272
PDF is available here.
Abstract
We present a case series of 10 patients with hyperhidrosis and a history of partial response to botulinum toxin type A monotherapy. With the addition of AC 15% in a salicylic acid 2% gel base, 5 patients achieved 75% to 100% reduction in sweating and 5 patients achieved 100% reduction in sweating. A...
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PMID: 21877507
PDF is available here.
Abstract
A novel functional tweezer based on uracil-appended glycyrrhetinic acid with excellent gelation ability was synthesized, and the gel could transform to sol by F(-) and Hg(2+).
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PMID: 21657225
PDF is available here.
Abstract
We postulated that the use of platelet-rich plasma (PRP) in contrast to platelet-poor plasma and pure fibrinogen as the basic material leads to an increased release of autologous platelet-derived growth factor (PDGF)-AB, which may have a consequent positive effect on tissue development. Therefore, w...
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PMID: 21413900
PDF is available here.
Abstract
Myofibroblast transdifferentiation plays a crucial role in the development and progression of renal tubulointerstitial fibrosis. However, the significance of α-smooth muscle actin (α-SMA) expression, which is the major morphological characteristic of myofibroblasts, remains to be d...
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PMID: 21630215
PDF is available here.
Abstract
Myofibroblast transdifferentiation plays a crucial role in the development and progression of renal tubulointerstitial fibrosis. However, the significance of α-smooth muscle actin (α-SMA) expression, which is the major morphological characteristic of myofibroblasts, remains to be d...
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PMID: 21630215
PDF is available here.
Abstract
Myofibroblast transdifferentiation plays a crucial role in the development and progression of renal tubulointerstitial fibrosis. However, the significance of α-smooth muscle actin (α-SMA) expression, which is the major morphological characteristic of myofibroblasts, remains to be d...
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PMID: 21630215
PDF is available here.
Abstract
It was more than 50 years ago that an appearance of birefringence in alginate gels prepared under cation flow was reported for the first time, however, the anisotropic structure of the alginate gel has not been studied in detail. In the present study, anisotropic Ca-alginate gels wer...
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PMID: 21504159
PDF is available here.
Abstract
A sol-gel microarray system was developed for a protein interaction assay with high activity. Comparing to 2-dimensional microarray surfaces, sol-gel can offer a more dynamic and broad range for proteins. In the present study, this sol-gel-integrated protein array was used in binding...
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PMID: 21749295
PDF is available here.
Abstract
The aim of the present investigation is to encapsulate rofecoxib in niosomes and incorporate the prepared niosomes into dermal gel base for sustained therapeutic action. Niosomes were prepared by lipid film hydration technique and were analyzed for size, entrapment efficiency and drug retention capac...
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PMID: 21702223
PDF is available here.
Abstract
To investigate the influence of calcium phosphate enhanced home whitening agents on human enamel and dentin surface microhardness and ultramorphology.
Five intact molars crowns were used for ultrastructural analysis and five for microhardness test. Each resulting coro...
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PMID: 21874930
PDF is available here.
Abstract
Bacterial vaginosis (BV) recurs frequently after metronidazole treatment. This randomized, single-masked clinical trial evaluated the efficacy of topical application of 62% ethyl alcohol in emollient gel (gel) to the penis by male partners of women diagnosed with BV for preventing po...
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PMID: 22256334
PDF is available here.
Abstract
Sticky yellow rectangle traps have been used for many years to capture Rhagoletis (Diptera: Tephritidae) fruit flies. Traditional sticky yellow traps are coated with a sticky gel (SG) that can leave residues on the hands of users. An alternative to SG on traps are hot melt pressure sensitive adhesive...
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PMID: 21735911
PDF is available here.
Abstract
The frequent economic losses incurred with H9N2 low pathogenic avian influenza viruses (LPAI) infection have raised serious concerns for the poultry industry. A 1-dose regimen with inactivated H9N2 LPAI vaccine could not prevent vaccinated poultry from becoming infected and from shedding wild viruses...
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PMID: 21489949
PDF is available here.
Abstract
Two series of poly(ether-ester)-based bis-functional macromers terminated with acrylate groups and a well-defined number of ester bonds were synthesized. One series had a chain of 1, 3 or 5 ester bonds at both ends of the central poly(ethylene glycol) block (molecular weight, about 1...
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PMID: 21095246
PDF is available here.
Abstract
The purpose of this study was to prepare a temperature-sensitive gel containing silver nanoparticles and to investigate its anti-bacterial properties in vitro. The aqueous gel was prepared using Pluronic F127 (18-22%) and Pluronic F68 (3-9%) in a cold method to obtain a proper gelati...
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PMID: 21612154
PDF is available here.
Abstract
We report a case of primary cutaneous aspergillosis infection in a nonhealing scalp wound of an immunocompetent elderly patient. The patient had a cutaneous malignancy of the scalp treated with surgical excision but complicated by poor wound healing. Fungal culture of the nonhealing wound revealed A...
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PMID: 21644495
PDF is available here.
Abstract
A large series of protein pathway components have been shown to be dysregulated in Down syndrome (DS) brain. No information about pathomechanisms linked to the trisomic state can be obtained from adult DS brain, however, as neurodegeneration occurs from the fourth decade. The aim of...
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PMID: 21262400
PDF is available here.
Abstract
Dendritic epithelial keratitis is most commonly caused by infections of herpes simplex virus (HSV) type 1 (HSV-1), and less frequently by HSV type 2 (HSV-2). Ganciclovir, a guanosine nucleoside analogue, is a well established broad-spectrum antiviral agent that inhibits replication of viral DNA and i...
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PMID: 21443283
PDF is available here.
Abstract
Nuclear magnetic resonance spectroscopy (NMR) has been widely used to determine water molecular mobility in food systems. This study aimed to examine the effects of matrix structure and solutes on the dynamics of water molecules in model mixed systems, glycerol-agar-water gels, using low- and high-re...
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PMID: 21375332
PDF is available here.
Abstract
The bilayer phase transitions from the ripple gel phase (P'(β)) to the liquid-crystal phase (L(α)) of a series of 1,2-diacylphosphatidylcholines containing a linear saturated acyl chain (C=14-19) have been studied by high-pressure scanning microcalorimetry. It has been shown that at ambient pressur...
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PMID: 21377445
PDF is available here.
Abstract
This study aimed to evaluate the degree of colour change after an in-office vital tooth bleaching procedure with a 35% hydrogen peroxide gel using a spectrophotometer. The study also determined the patients' perceptions of the colour change and assessed the post operative sensitivity during the first...
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PMID: 21608500
PDF is available here.
Abstract
The effects of three different decontaminating solutions in clinical use for peri-implantitis therapy on the chemical structure and surface roughness of commercially pure (CP) Ti were investigated. A further aim was to survey the response of the biological environment to these changes, by examining t...
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PMID: 21789931
PDF is available here.
Abstract
We developed a novel method for preparing carrier-free epithelial cell sheets, which have potential for use in repairing defects of the ocular surface. Stratified corneal epithelial cell sheets were prepared in culture dishes coated with biodegradable type I collagen. Haematoxylin and eosin staining...
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PMID: 20603893
PDF is available here.
Abstract
A major obstacle in tissue engineering is overcoming hypoxia in thick, three-dimensional (3D) engineered tissues, which is caused by the diffusional limitations of oxygen and lack of internal vasculature to facilitate mass transfer. Modular tissue engineering is a bio-mimetic strateg...
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PMID: 20653045
PDF is available here.
Abstract
Pulsed electric field (PEF) treatment has been proposed as a decontamination method for labile matrices used in tissue engineering applications. Through the application of PEF, a non-thermal treatment that causes bacterial inactivation through the irreversible rupture of microbial ce...
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PMID: 21210508
PDF is available here.
Abstract
A phenyl-based hybrid organic - inorganic coating has been synthesized and processed by hard X-ray lithography. The overall lithography process is performed in a two-step process only (X-rays exposure and chemical etching). The patterns present high aspect ratio, sharp edges, and hig...
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PMID: 21218788
PDF is available here.
Abstract
We undertook a proteomic analysis of N. tabacum trichomes in order to identify their protein complement. Efficient trichome isolation was obtained by abrading frozen leaves. After homogenization, soluble proteins and a microsomal fraction were prepared by centrifugation. Gel-based and gel-free prote...
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PMID: 21268273
PDF is available here.
Abstract
Alginate based mineral oil entrapped emulsion gel (MOEG) buoyant beads of domperidone were prepared by emulsion gelation technique. The prepared beads were evaluated for particle size, surface morphology, buoyancy, actual drug content and entrapment efficiency. Effect of different oils (castor oil, o...
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PMID: 21485710
PDF is available here.
Abstract
Glioma cells are exposed to elevated interstitial fluid flow during the onset of angiogenesis, at the tumor periphery while invading normal parenchyma, within white matter tracts, and during vascular normalization therapy. Glioma cell lines that have been exposed to fluid flow forces...
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PMID: 21637818
PDF is available here.
Abstract
The chemical-mechanical removal of caries involves the chemical softening of the infected dentin, following by the mechanical removal of the softened tissue using non-cutting manual instruments. Papacárie (Fórmula&Açāo, Sao Paulo, Brazil) is a product in gel form used for the chemical-mechanical...
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PMID: 21678665
PDF is available here.
Abstract
We describe how cell-seeded Type-I collagen gels can be adapted to provide powerful 3D models to support a wide range of research applications where cell/substrate alignment, density, stiffness/compliance, and strain are critical factors. In their fully hydrated form, rectangular collagen gels can b...
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PMID: 21042973
PDF is available here.
Abstract
Self-assembled liposome gel from liposome and cholesterol-end capped polyethylene glycol, was systematically investigated by rheological method, especially in the aspect of its recovery ability upon either mechanical deformation or temperature change. The liposome gel was found to have rheological b...
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PMID: 20855187
PDF is available here.
Abstract
We have previously shown that besides its interaction with anionic lipids, the cyt c is also able to cross neutral lipid membranes. In this work, with the help of AFM and punch-through experiments, we have measured the force required to penetrate the membrane in the fluid and in the gel phases with...
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PMID: 20832261
PDF is available here.
Abstract
Thermal treatment has become an alternative modality for cancer treatment. Low temperature freezing and high temperature heating kill tumor cells effectively through direct and indirect injuries by biochemical and physical stresses. Hyperthermia at a mildly elevated temperature has also been reported...
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PMID: 21766157
PDF is available here.
Abstract
We used poloxamer gels to develop a controlled release formulation of hGH. The objective of this study was to develop an in situ gel forming drug delivery system for hGH using the minimum possible ratio of poloxamer 407 (P407). Decreasing the concentration of poloxamer could reduce the risk of hyper...
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PMID: 21648286
PDF is available here.
Abstract
To compare the efficacy and side effects profile of topical 2% lidocaine gel with injectable 2% lidocaine solution as local anaesthetics for incision and curettage of chalazion.
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PMID: 21809603
PDF is available here.
Abstract
We incorporate silver nitrate within silica sol-gel derived films produced using a simple procedure at relative low temperatures (close to ambient). A compact time-resolved fluorescence microscope equipped with a semiconductor laser was used to photoactivate the silver ions to form localised metalli...
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PMID: 20859589
PDF is available here.
Anne E Burke,
Kurt Barnhart,
Jeffrey T Jensen,
Mitchell D Creinin,
Terri L Walsh,
Livia S Wan,
Carolyn Westhoff,
Michael Thomas,
David Archer,
Hongsheng Wu,
James Liu,
William Schlaff,
Bruce R Carr and
Diana Blithe
Abstract
To estimate whether a gel containing the spermicide C31G was noninferior to a commercially available product containing nonoxynol-9.
Participants were healthy, sexually active women aged 18-40 years. Measured outcomes included pregnancy rates, continuation rates, adverse events, and acceptability. T...
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PMID: 21099590
PDF is available here.
Abstract
We propose that these materials function by retarding cytokine diffusion, with the non-crosslinked polymers being capable of retarding the diffusion of cytokines in the extracellular matrix and preventing engagement with receptors. In contrast, crosslinked materials have long diffusion lengths into...
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PMID: 20601239
PDF is available here.
Abstract
We performed serial MPM and mechanical tests on acellular and cellularized (normal human lung fibroblasts) collagen hydrogels, before and after glutaraldehyde crosslinking. Following gel contraction over 16 days, cellularized collagen gel content approached that of native connective tissues (∼200...
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PMID: 20620246
PDF is available here.
Abstract
Supramolecular gels formed by an isonicotinic acid derivative in toluene are selectively disassembled in the presence of catechol. The results represent a unique example of molecular recognition associated to gel rupture which is of interest, for example, in controlled drug release applications.
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PMID: 20865202
PDF is available here.
Abstract
We present a model for actin-based motility that combines the dynamics of the semiflexible region at the leading edge of the lamellipodium with actomyosin gel properties in the bulk described by the theory of active polar gels. We calculate the velocity of the lamellipodium determined by the interac...
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PMID: 21230518
PDF is available here.
Abstract
The acne-specific quality of life (Acne-QoL) questionnaire was developed to measure the impact of facial acne across 4 domains (acne symptoms, role-emotional, self-perception, role-social) of health-related quality of life (HRQL). This analysis assessed the impact of clindamycin phosphate 1.2%-benzo...
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PMID: 21214129
PDF is available here.
Abstract
Recently, it has been shown that ingestion of solutions with glucose (GLU) and fructose (FRC) leads to 20%–50% higher CHO oxidation rates compared with GLU alone. Although most laboratory studies used solutions to deliver CHO, in practice, athletes often ingest CHO in the form of gels (semisolid)....
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PMID: 20404763
PDF is available here.
Abstract
Kinetics of hydrolysis induced swelling as well as pure swelling of a novel class of pH responsive biocompatible polymer gels was studied. Poly(aspartic acid) gels were prepared by hydrolysis of chemically cross-linked poly(succinimide) networks. The volume change of spherical gels of different size...
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PMID: 20730186
PDF is available here.
Abstract
We have previously described a novel method to topically silence target genes in a wound bed with small interfering (si)RNA. We hypothesized that silencing p53 results in improved diabetic wound healing and augmentation of vasculogenic mediators. Paired 4-mm stented wounds were created on diabetic d...
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PMID: 20955346
PDF is available here.
Author(s) unavailable
Abstract
Ketoprofen gels are more harmful than beneficial, and their withdrawal from the French market in late 2009 was a welcome measure. Unfortunately, they were back on the market in early 2010 following legal action. Healthcare professionals and patients should rely on solid evidence rather than decision...
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PMID: 21180371
PDF is available here.
Abstract
The effects of alcohol treatment on the activity and loading amount of Candida rugosa lipase (CRL), Candida Antarctica lipase B (CALB) and Porcine Pancreas lipase (PPL) immobilized on methyl-modified silica aerogels were investigated, and the fluorescent analysis was used to explore...
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PMID: 20576560
PDF is available here.