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All › Complex Mixtures › Biological Products

Biological Products (7)

Articles on Biological Products

  1. Biologics debate heats up between FDA, NCCN.
    John J Carroll

    Manag Care 20(9):30-2 (2011) PMID 21991859

  2. Organic chemistry: Overcoming catalytic bias.
    Daesung Lee

    Nature 471(7339):452-3 (2011) PMID 21430766

  3. Natural products as a source of Alzheimer's drug leads.
    Philip P Williams, Analia A Sorribas, and Melanie-Jayne R MJ Howes

    Nat Prod Rep 28(1):48-77 (2011) PMID 21072430

    This review focuses on recent developments in the use of natural products as therapeutics for Alzheimer's disease. The compounds span a diverse array of structural classes and are organized according to their mechanism of action, with the focus primarily on the major hypotheses. Overall, the review...
  4. Molecular basis of applied biological therapeutics.
    U U Andersson and K J KJ Tracey

    J Intern Med 269(1):2-7 (2011) PMID 21197710

  5. Naturally-occurring nitro compounds.
    Ronald R Parry, Shirley S Nishino, and Jim J Spain

    Nat Prod Rep 28(1):152-67 (2011) PMID 21127810

    Naturally-occurring nitro compounds display great structural diversity, and a wide range of biological activities. This review summarizes current information on the structures of naturally-occurring nitro compounds and on the biosynthesis of the nitro group.
  6. NMR methods for unravelling the spectra of complex mixtures.
    Ramon R Novoa-Carballal, Eduardo E Fernandez-Megia, ... Ricardo R Riguera

    Nat Prod Rep 28(1):78-98 (2011) PMID 20936238

    The main methods for the simplification of the NMR of complex mixtures by selective attenuation/suppression of the signals of certain components are presented. The application of relaxation, diffusion and PSR filters and other techniques to biological samples, pharmaceuticals, foods, living organism...
  7. Implementation of the biosimilar pathway: economic and policy issues.
    Henry H Grabowski, Genia G Long, and Richard R Mortimer

    Seton Hall Law Rev 41(2):511-57 (2011) PMID 21739758

  8. Informed by the European Union experience: what the United States can anticipate and learn from the European Union's regulatory approach to ...
    Donna M DM Gitter

    Seton Hall Law Rev 41(2):559-92 (2011) PMID 21739759

  9. Bringing natural products into the fold - exploring the therapeutic lead potential of secondary metabolites for the treatment of protein-mis...
    P Matthew PM Joyner and Robert H RH Cichewicz

    Nat Prod Rep 28(1):26-47 (2011) PMID 20927454

    A review with 187 references, describing natural products that exhibit bioactive properties relevant to the treatment of protein aggregation-related neurodegenerative diseases (e.g., Huntington's, Parkinson's, and prion diseases) and comparing the chemical properties of these secondary metabolite le...
  10. Methods and options for the heterologous production of complex natural products.
    Haoran H Zhang, Brett A BA Boghigian, ... Blaine A BA Pfeifer

    Nat Prod Rep 28(1):125-51 (2011) PMID 21060956

    This review will detail the motivations, experimental approaches, and growing list of successful cases associated with the heterologous production of complex natural products.