Abstract
Compliance to REE increased from 9% before screening to 66.5% after screening (P < .0001). Good quality fundus images were obtained in 93% of the eyes. CONCLUSION:Introduction of nDFP for diabetic retinopathy screening in the family practice clinic can result in a dramatic increase in compliance to R...
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PMID: 21688766
PDF is available here.
Abstract
In established dementia, administration of the CogState tasks appears sensitive to cognitive impairment in dementia. Repeat administration also provided acceptable stability and test-retest reliability with minimal practice effects at short test-retest intervals despite intervening cognitive challen...
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PMID: 21636581
PDF is available here.
Abstract
We describe a first experiment in routine use of a virtual slides system within a pathology practice whose technical facilities are not located on the same geographical site as pathologists.
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PMID: 21601110
PDF is available here.
Abstract
To conduct a preliminary study testing the validity of the Odiosoft-Rhino (OR) in the evaluation of nasal patency in patients with nasal septal deviation and compare the results with visual analogue score (VAS) of nasal obstruction and rhinomanometry (RMM).
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PMID: 21468373
PDF is available here.
Abstract
The automated segmentation of vessel tree structures is a crucial preprocessing stage in computer aided diagnosis (CAD) schemes of interstitial lung disease (ILD) patterns in multidetector computed tomography (MDCT). The accuracy of such preprocessing stages is expected to influence...
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PMID: 21317088
PDF is available here.
Abstract
We developed a computerized scheme to automatically segment the 3-D human airway tree depicted on computed tomography (CT) images. The method takes advantage of both principal curvatures and principal directions in differentiating airways from other tissues in geometric space. A "puzzle game" proced...
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PMID: 20851792
PDF is available here.
Abstract
We propose a general framework for detecting and characterizing target lesions almost instantaneously. This framework relies on a feature space automatically derived from a set of reference image samples representing target lesions, including atypical target lesions, and those eye structures that ar...
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PMID: 21292586
PDF is available here.
Abstract
We aimed to update our knowledge of how key quantitative parameters describing CSF dynamics may be used in diagnosis of shunt-responsive hydrocephalus and in the assessment of shunt function....
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PMID: 21208195
PDF is available here.
Abstract
Of 79 patients with adequate brush biopsy samples with matching scalpel biopsies, 27 revealed histopathologic evidence of dysplasia or carcinoma, 26 of which were independently identified with the oral brush biopsy (sensitivity: 96.3% - 95% CI, 87%-100%). 52 oral lesions did not reveal any histopath...
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PMID: 21864339
PDF is available here.
Abstract
The techniques most frequently used within a screening context (otoacoustic emissions and click auditory brainstem response) have well-known limitations in hearing loss detection.
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PMID: 21215381
PDF is available here.
Abstract
We aimed at evaluating how the use of this tool may aid physicians in appropriately using anticoagulants. This was an epidemiological, cross-sectional survey of acute medically ill patients with limited mobility treated by general practitioners and internists. Risk assessment for VTE by the treating...
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PMID: 20978716
PDF is available here.
Abstract
We review the current knowledge pertaining to the treatment of ILD in systemic sclerosis, and also address the various challenges involved as well as implications for the future....
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PMID: 21586221
PDF is available here.
Abstract
We propose a CP that makes use of evolved rule sets generated by a genetic algorithm (GA). The rule-based GA has the advantage of being human readable. We apply our method on two real-world datasets for medical diagnosis, one dataset for breast cancer diagnosis, which contains data gathered from fin...
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PMID: 21062682
PDF is available here.
Abstract
The review is concerned with molecular diagnostic tools for influenza A viruses. Test systems based on PCR, real-time PCR, IEA, sequenation, and microchip-based methods are discussed as applied at this Institute for comprehensive monitoring influenza A viruses.
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PMID: 21786594
PDF is available here.
Abstract
There is a great challenge in identifying the early diagnosis of the Alzheimer's disease, which has become the most frequent cause of dementia in the last few years, being responsible for 50% of the cases in western countries. The main focus of the work is the development of a multicriteria model for...
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PMID: 21431596
PDF is available here.
Abstract
To investigate the reliability and validity of computerized anxiety assessment with New Zealand children, and to explore children's preferences for the method of anxiety assessment.
A validation study including test-retest reliability, and mean anxiety scores for items on the computerised Smiley Fac...
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PMID: 21197816
PDF is available here.
Abstract
Conventional computer-assisted detection (CADe) systems in screening mammography provide the same decision support to all users. The aim of this study was to investigate the potential of a context-sensitive CADe system which provides decision support guided by each user's focus of attention during vi...
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PMID: 21158284
PDF is available here.
Abstract
This article presents a computer-aided diagnosis technique for improving the accuracy of the early diagnosis of Alzheimer's disease (AD). Two hundred and ten 18F-FDG PET images from the ADNI initiative [52 normal controls (NC), 114 mild cognitive impairment (MCI), and 53 AD subjects] are studied.
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PMID: 21158320
PDF is available here.
Abstract
We describe an automated system to identify follicles in IHC-stained tissue sections. A unique feature of the system described here is the use of texture and color information to mimic the process that a human expert might use to identify follicle regions. Comparison of system-generated results with...
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PMID: 20639174
PDF is available here.
Abstract
This article is a transcript of a conversation that took place with Edwin Shneidman, PhD, on August 19, 2008. Recent advances in machine learning, particularly neurocognitive computing, have provided a fresh approach to the idea of using computers to analyze the language of the suicidal person. Here...
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PMID: 21034214
PDF is available here.
Abstract
Flow cytometry (FCM) is widely used in cancer research for diagnosis, detection of minimal residual disease, as well as immune monitoring and profiling following immunotherapy. In all these applications, the challenge is to detect extremely rare cell subsets while avoiding spurious p...
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PMID: 20563720
PDF is available here.
Abstract
A novel content-based information retrieval framework, designed to cover several medical applications, is presented in this paper. The presented framework allows the retrieval of possibly incomplete medical cases consisting of several images together with semantic information. It rel...
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PMID: 20813626
PDF is available here.
Abstract
The purpose of this study is size-adapted segmentation of individual microcalcifications in mammography, based on microcalcification scale-space signature estimation, enabling robust scale selection for initialization of multiscale active contours. Segmentation accuracy was evaluated by the area ove...
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PMID: 20080386
PDF is available here.
Abstract
We show that our method leads to significant improvement when compared to previous work. We are able to distinguish between normal shapes and shapes that possess a pathology with an accuracy of almost 100%. Moreover, we can differentiate between the different pathology groups with an average accurac...
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PMID: 20605487
PDF is available here.
Yosuke Tsuji,
Ken Ohata,
Shotaro Umezawa,
Suguru Takeuchi,
Masau Sekiguchi,
Akiko Ohno,
Takafumi Ito,
Hideyuki Chiba,
Makoto Yamawaki,
Kantaro Hisatomi,
Takuma Teratani and
Nobuyuki Matsuhashi
Abstract
We must be careful of the risk of capsule retention. The combination of capsule endoscopy, double balloon endoscopy, and traditional examination modalities including radiography or computed tomography will make it possible to diagnose and treat small bowel carcinoma at an early stage, and further pr...
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PMID: 20716866
PDF is available here.
Abstract
The objective of this study was to develop a computerized test of prone extension to measure performance of prone extension in children 4 to 6 years of age. The participants were selected from kindergartens, comprising 132 boys and 107 girls with a mean age of 5 yr. 2 mo. (SD = 6 mo.). Sensitivity a...
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PMID: 21058600
PDF is available here.
Abstract
A composite index, the Tissue Optical Index (TOI), showed a significant ( approximately 50%) decrease over the nearly 18 weeks of chemotherapy. Tumor response was sensitive to the type of chemotherapy agent, and functional indices fluctuated in a manner consistent with dynamic tumor physiology. Fina...
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PMID: 20542448
PDF is available here.
Abstract
The Pediatric Evaluation of Disability Inventory (PEDI) is a useful clinical and research assessment, but it has limitations in content, age range, and efficiency. The purpose of this article is to describe the development of the item bank for a new computer adaptive testing version of the PEDI (PED...
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PMID: 20608855
PDF is available here.
Abstract
Intraoperative diagnosis of sentinel node metastases enables an immediate decision to proceed to axillary lymph node dissection, avoiding a second operation in node-positive women with breast cancer.
An optical scanner was developed that interrogated the cut surface o...
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PMID: 20593429
PDF is available here.
Abstract
The authors' ANN can effectively discriminate malignant abnormalities from benign ones and accurately predict the risk of breast cancer for individual abnormalities.
Copyright (c) 2010 American Cancer Society....
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PMID: 20564067
PDF is available here.
Abstract
In this article, we describe the function of computer-aided detection (CAD), the history of CAD in mammography, its current status, the differences between CAD in analog mammography and digital mammography, detection performance, and appropriate directions for its use.
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PMID: 20224923
PDF is available here.
Abstract
We describe the current status of mammographic screening and investigate how digital mammography is used in screening in Japan. Despite the widespread use of digital mammographic equipment, the mammographic screening rate for invited women is very low. In the majority of cases, digital hard copy ima...
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PMID: 20072821
PDF is available here.
Abstract
As a promising non-invasive imaging technique, functional near infrared spectroscopy (fNIRS) has recently earned increasing attention in resting-state functional connectivity (RSFC) studies. Preliminary fNIRS-based RSFC studies adopted a seed correlation approach and yielded interesting results. How...
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PMID: 20211741
PDF is available here.
Abstract
The Star-Ring Test is a rapid and reliable test of contrast sensitivity....
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PMID: 20473233
PDF is available here.
Abstract
This report reviews methods applicable in workplace spirometry monitoring for the identification of individuals with excessive lung function decline. Specific issues addressed include 1) maintaining longitudinal spirometry data precision at an acceptable level so that declines due to adverse physiol...
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PMID: 20550761
PDF is available here.
Abstract
Compliance index C(i) decreased during the infusion test, proportionally inverse to the rise in intracranial pressure controlled by the external infusion of saline (R=-0.76; p<0.005). A relative change in compliance (from baseline to the plateau phase of the study) was positively associated with gre...
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PMID: 20092676
PDF is available here.
Abstract
The symptoms of liver diseases are not apparent in the initial stage, and the condition is usually quite serious when the symptoms are obvious enough. Most studies on liver disease diagnosis focus mainly on identifying the presence of liver disease in a patient. Not many diagnosis models have been d...
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PMID: 20591425
PDF is available here.
Abstract
Automated audiometry provides reliable, accurate, and time-efficient hearing assessments for normal-hearing and hearing-impaired adults. Combined with an asynchronous telehealth model it holds significant potential for reaching underserved areas where hearing health professionals are unavailable....
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PMID: 20575723
PDF is available here.
Abstract
As issues with audio latency, break-up, and echo were observed, some modifications to the technology may improve system effectiveness and usability. However, the overall positive results of this study support the validity and reliability of the assessment of children's literacy skills via telehealth...
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PMID: 20575724
PDF is available here.
Abstract
Patients receiving ECT displayed a range of visual and visuospatial deficits over the course of their treatment. These deficits were most prominent for tasks dependent on the use of the right medial temporal lobe; frontal lobe function may also be implicated. The CANTAB appears to be a useful instru...
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PMID: 19775495
PDF is available here.
Abstract
The CBCG-generated boundaries were shown to be comparable with the manually delineated boundaries. The area under the receiver operating characteristic curve (AUC) and differentiation accuracy were 0.968 +/- 0.010 and 93.1% +/- 0.7, respectively, for all 520 breast lesions. At the 5% significance le...
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PMID: 20501714
PDF is available here.
Abstract
We studied the ability of the REMstar Pro (RSP2, a brand of continuous positive airway pressure (CPAP) device) to identify abnormal breathing events in subjects with OSA and compared this with breathing events simultaneously determined by laboratory-based PSG.
We evaluated 10 subjects previously dia...
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PMID: 19826848
PDF is available here.
Abstract
We tested ApneaLink's diagnostic performance in a patient population with high prevalence of sleep apnea.
ApneaLink was applied simultaneously with in-laboratory polysomnography (PSG) (n = 102, 24 female, age 54.7 years) and sequentially with PSG in the unattended home setting (n = 131, 37 female, a...
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PMID: 19714380
PDF is available here.
Abstract
In clinical neuropsychology a huge number of neuropsychological tests have been developed, and the corpus of these instruments is always increasing. Because of this, the question has been raised as to which are the most usefull instruments that provide the best neuropsychological profiles of the sub...
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PMID: 20562739
PDF is available here.
Abstract
Sex differences on visuospatial tests are among the most reliably replicated. It is unclear to what extent these performance differences reflect underlying differences in skills or testing factors. To assess whether testing medium and response format affect visuospatial sex differences, performances...
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PMID: 20681334
PDF is available here.
Abstract
Sport-related concussion is a common problem encountered by pediatricians and other primary care physicians. Assessment of concussion is based on clinical evaluation. The Zurich consensus statement provides a basic framework to guide concussion management decisions and recommends an individualized a...
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PMID: 20538149
PDF is available here.
Abstract
The results indicate the shoulder CAT was efficient and support the precision, sensitivity, and responsiveness of CAT-FS measures....
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PMID: 20395304
PDF is available here.
G S Scotland,
P McNamee,
A D Fleming,
K A Goatman,
S Philip,
G J Prescott,
P F Sharp,
G J Williams,
W Wykes,
G P Leese,
J A Olson and
Scottish Diabetic Retinopathy Clinical Research Network
Abstract
Algorithm (b) is more cost-effective than the algorithm based on quality assessment and MA/DH detection. With respect to the value of introducing automated detection systems into screening programmes, automated grading operates within the recommended national standards in Scotland and is likely to b...
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PMID: 19965826
PDF is available here.
Alan D Fleming,
Keith A Goatman,
Sam Philip,
Graeme J Williams,
Gordon J Prescott,
Graham S Scotland,
Paul McNamee,
Graham P Leese,
William N Wykes,
Peter F Sharp,
John A Olson and
Scottish Diabetic Retinopathy Clinical Research Network
Abstract
Introduction of algorithms for exudates and haemorrhages resulted in a statistically significant increase in the sensitivity for detection of observable/referable retinopathy from 94.9% (95% CI 93.5 to 96.0) to 96.6% (95.4 to 97.4) without affecting manual grading workload. CONCLUSION: Automated det...
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PMID: 19661069
PDF is available here.
Abstract
We focus the discussion on the current status of proteomics analysis of cellular proteins and HCC biomarker identification, with a special highlight on the potential of the cell-based HBV replication system for the identification of prognostic HCC biomarkers.
(c) 2010 Elsevier B.V. A...
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PMID: 20188222
PDF is available here.
Abstract
The heart rate was significantly higher when the neonates were awake, and when awake higher in girls than in boys. While there was no statistically significant difference between the QTc when the babies were awake or asleep in leads 1 and 3, this reached the level of mathematical significance in the...
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PMID: 20135130
PDF is available here.
Abstract
Our data demonstrate some new aspects of MCP-1 measurement in patients with MI, but do not corroborate many earlier observations....
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PMID: 20140679
PDF is available here.
Abstract
With clinical improvement of acute CHF exacerbations, there was more homogenous distribution of lung vibration energy, as demonstrated by the increased geographical area of the vibration energy image. Lung sound analysis may be useful to track in acute CHF exacerbations....
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PMID: 20529550
PDF is available here.
Abstract
We model and process information in biomedicine and impact the emerging field of nanomedicine most strongly. In this article, we review work in nanoinformatics and DNA (and RNA)-based computing, including applications in nanopediatrics. We analyze their scientific foundations, current research and p...
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PMID: 20118825
PDF is available here.