Abstract
We discuss a sensor-integrated system model for metabolic syndrome prediction with workflow system. This model measures not only a cell temperature variation using invasive method but also controlling simulation for metabolic syndrome prediction. To identify the system realization, we discuss the sc...
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PMID: 21342807
PDF is available here.
Abstract
Objective. To establish an early diagnostic system for hypoxic ischemic encephalopathy (HIE) in newborns based on artificial neural networks and to determine its feasibility. Methods. Based on published research as well as preliminary studies in our laboratory, multiple noninvasive indicators with hi...
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PMID: 21811381
PDF is available here.
Abstract
During a severe outbreak of bacterial heart rot that occurred in pineapple plantations on Oahu, Hawaii, in 2003 and years following, 43 bacterial strains were isolated from diseased plants or irrigation water and identified as Erwinia chrysanthemi (now Dickeya sp.) by phenotypic, mol...
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PMID: 21050038
PDF is available here.
Abstract
The clinical usefulness of a diagnostic test is determined by the extent to which it helps to modify the pretest probability of occurrence of a certain diagnosis. For this purpose, the calculation and application of likelihood ratios (LR) is a very useful tool. Every possible result of a test has a...
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PMID: 21046715
PDF is available here.
Abstract
To explore the clinical value of CYFRA 21-1, HER-2/neu and NSE as tumor markers for differential diagnosis of malignant and benign pleural effusion.
Radioimmunoassay and ELISA were used to detect the serum and effusion levels of CYFRA 21-1, HER-2/neu and NSE in 62 patients with malignat pleural effu...
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PMID: 20619104
PDF is available here.
Abstract
We discuss the current consensus on development of saliva/oral fluid-based diagnostics and provide a summary of recent research advancements of the Texas-Kentucky Saliva Diagnostics Consortium. In the foreseeable future, current research on saliva based diagnostic methods could revolutionize health...
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PMID: 20737986
PDF is available here.
Abstract
These results suggest that delivering critical information to patients after administering a test and immediately before giving the results may not be optimal....
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PMID: 20556876
PDF is available here.
Abstract
Substantial differences in diagnostic practices that are unlikely to be related to patient characteristics are observed across U.S. regions. The use of clinical or claims-based diagnoses in risk adjustment may introduce important biases in comparative-effectiveness studies, public reporting, and pay...
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PMID: 20463332
PDF is available here.
Abstract
In screening tests for dysphagia conducted using videoendoscopy in 81 subjects over 75-years-old apparent liquid aspiration was found in 26 (32%). In 2 of these 26 saliva aspiration was observed. Logistic analysis of aspiration versus clinical symptoms, including endoscopic findings, showed a signif...
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PMID: 20653193
PDF is available here.
Abstract
We hypothesize that a treatment of an equinus deformity should improve postural control. Balance control was assessed by static posturography on the Balance Master. Nine diplegic children, six girls and three boys, participated in the study. Assessment was conducted before and after treatment of the...
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PMID: 20101192
PDF is available here.
Abstract
Duplication of medical testing results in a financial burden to the healthcare system. Authors undertook a retrospective review of duplicate testing on patients receiving coordinated care across two institutions, each with its own electronic medical record system. In order to determine whether dupli...
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PMID: 20442154
PDF is available here.
Abstract
BP neural networks may, sometimes, predict clinical diagnoses with accuracies similar to those of other methods. However, traditional statistical procedures, such as regression analyses need to be added for testing their accuracies against alternative methods. Nonetheless, BP neural networks have gr...
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PMID: 20001439
PDF is available here.
Abstract
The aim of this work was to study clinical manifestations of abdominal tuberculosis (AT) and its diagnosis. It included 142 patients examined in Ulyanovsk region in 1990-2006. 88.7% of them first applied to general practitioners who diagnosed AT in 69.7% of the cases (half of them postmortem). AT wa...
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PMID: 21105474
PDF is available here.
Abstract
We reported that VacA induces autophagy. Multilamellar autophagosomes are detected in gastric epithelial cells that are distinct from the large vacuoles formed by VacA. Furthermore, inhibition of autophagy stabilizes VacA and reduces vacuolation in the cells indicating that the toxin is being degrad...
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PMID: 19875940
PDF is available here.
Abstract
Biotech specialists met on November 19, 2009 for their traditional 'Olten Meeting'. On their agenda: to orientate biotech research to more efficient diagnostic instruments and therapies to lead the fight against incurable diseases. A look behind the scenes of current research in Swiss biotechnology....
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PMID: 21137693
PDF is available here.
Abstract
In medicine, an adverse effect (AE) is a harmful and undesired effect resulting from a medication or intervention and procedures. Some AEs only occur when starting, increasing or discontinuing a treatment; in this case they are a function of dosage or drug levels at the target organs, or they may al...
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PMID: 20393687
PDF is available here.
Abstract
A total of 26 FCCs, each indicating a common medical problem and its severity, constituted approximately 90 percent of all FCCs assigned at recruitment centers between 2001 and 2006. Major contributors to medical profiling outcomes were underweight, asthma, chronic headache, mental illness, symptoma...
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PMID: 20845680
PDF is available here.
Abstract
This report makes recommendations on new therapeutic regimens for visceral and cutaneous leishmaniasis, on the use of rapid diagnostic tests, details on the management of Leishmania-HIV coinfection and consideration of social factors and climate change as risk factors for increased spread. Recommenda...
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PMID: 21485694
PDF is available here.
Abstract
In the general sense, nanomedicine is defined as the application of nanotechnologies including nanobiothechnologies in medicine. Under conditions of current rapid development of nanotechnologies, many terms and definitions lack clarity and precision and boundaries between traditional and nanotechnol...
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PMID: 20420215
PDF is available here.
Abstract
Major advances in the testing of oral fluid (e.g., saliva) may lead to the diagnosis and treatment of previously undiagnosed conditions and may enable dentists to manage oral disease more effectively. Such use of another body fluid, blood, is already well established. Blood is a complex tissue that...
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PMID: 20719097
PDF is available here.
Abstract
This article reviews the provisions of the European Patent Convention with regard to diagnostic methods practiced on the human or animal body. Moreover, it is also discussed the relevant jurisprudence (Case Law) interpreting the legal provisions. Some examples based on real cases are...
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PMID: 21095714
PDF is available here.
Abstract
This paper presents a novel discriminant analysis (DA) for feature extraction using mutual information (MI) and Fisher discriminant analysis (MI-FDA). Most DA algorithms for feature extraction are based on a transformation which maximizes the between-class scatter and minimizes the w...
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PMID: 21096912
PDF is available here.
Abstract
The characteristics of patients with AE and undesirable effects that occurred during pre-hospitalization period depended on whether they originated during ambulatory care or non-ambulatory care. Therefore prevention strategies should take these differences into account.
Copyright 2009 SECA. Publishe...
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PMID: 19857981
PDF is available here.
Abstract
We gain better insights into the best monitoring strategies and as there is experience with the second generation tyrosine kinase inhibitors (TKI). Certain observations about CML and its clinical course remain relevant, such at its triphasic course and the prognostic value of the Sokal and Hasford s...
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PMID: 20017605
PDF is available here.
Abstract
Tuberculosis continues to be a major health problem worldwide, affecting millions of people each year. Accurate and rapid diagnosis is key to controlling the disease, yet the traditional tests for TB produce results that are either inaccurate or take too long to be definitive. A fast and reliable di...
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PMID: 19883330
PDF is available here.
Abstract
In addition to psychological measures, nurse researchers have been working hard to integrate biological measures into their research in order to gain a comprehensive understanding of client health status. However, the fluctuating and interactive nature of biological systems makes biological measurem...
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PMID: 19760578
PDF is available here.
Abstract
With its cool climate, Finland has a lower prevalence of fungal infections than many other European countries that have hosted the annual congress of the European Society of Clinical Microbiology and Infectious Diseases. However, changing patterns of infection and drug resistance, and their impact o...
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PMID: 19722833
PDF is available here.
Abstract
These results suggest that prolonged formalin fixation has minimal effects on antigen detection for most commonly used antibodies. These results further validate the use of IHC in diagnostic pathology....
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PMID: 19398606
PDF is available here.
Abstract
The capability to assess physiological states, detect morbidity initiation and progression, and monitor posttreatment therapeutic outcomes through a noninvasive approach is one of the most desirable goals for healthcare research and delivery. Saliva, a multi-constituent oral fluid, has high potentia...
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PMID: 19824562
PDF is available here.
Abstract
In light of the results of our evidence synthesis and decision modelling we revisited the examination of PND screening against five of the NSC criteria. We found that the accepted criteria for a PND screening programme were not currently met. The evidence suggested that there is a simple, safe, prec...
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PMID: 19624978
PDF is available here.
Abstract
The cloned gene fragment exhibited complete similarity with the published sequence of gra8 gene by sequence analysis. rGRA8 was expressed in Escherichia coli in fusion with a very small tag and the soluble protein was purified by immobilized metal ion affinity chromatography. In immunoblot, serum sa...
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PMID: 19688020
PDF is available here.
Abstract
Rapid and accurate diagnosis of diseases is very important for appropriate treatment of patients. Recent advances in molecular-level interaction and detection technologies are upgrading the clinical diagnostics by providing new ways of diagnosis, with higher speed and accuracy. In particular, DNA mi...
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PMID: 19652509
PDF is available here.
Abstract
We describe modifications that allow the bone diagnostic instrument (BDI) [P. Hansma et al., Rev. Sci. Instrum. 79, 064303 (2008); Rev. Sci. Instrum. 77, 075105 (2006)], developed to test human bone, to test the femora of mice. These modifications include reducing the effective weight of the instrum...
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PMID: 19566227
PDF is available here.
Abstract
Mean deviation to the real cost was 52% with a correct estimation of an average 28%. No significant difference could be detected in this study among emergency department physicians, house officers and consultants in internal medicine regarding the cost awareness towards the items considered. CONCLUS...
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PMID: 19282761
PDF is available here.
Abstract
Conscious sedation is used frequently to perform procedures that may be undertaken with or without minimal sedation. Fracture manipulation can be performed with minimal discomfort in the awake patient using various techniques-for example, intravenous regional anesthesia, nerve blocks, and hematoma b...
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PMID: 19528768
PDF is available here.
Abstract
Owing to the heterogeneity of AML, the indication for allogeneic SCT (allo-SCT) requires an exact definition of the individual subentity and risk category. A comprehensive diagnostic approach is needed, which combines cytomorphology, cytogenetics, FISH, molecular genetics and immunophenotyping. Wher...
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PMID: 19363529
PDF is available here.
Abstract
Results were used to develop procedural pain guidelines and a physician order set as well as a medication reference grid to assist clinicians in the management of procedural pain. Furthermore, nurses were empowered by the revised guidelines to advocate for relief of pain based on the nursing assessm...
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PMID: 19395889
PDF is available here.