Abstract
The prevalence of peritoneal dialysis in France remains one of the lowest in Europe in spite of official recommendations in 2008. Progress in peritoneal catheter placement and a good knowledge of the management of catheter complications are essential. A more frequent use of biocompatible solutions sh...
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PMID: 21924862
PDF is available here.
Abstract
Attempts to determine the clinical significance of BRCA1/2 mutations in ovarian cancer have produced conflicting results.
To determine the relationships between BRCA1/2 deficiency (ie, mutation and promoter hypermethylation) and overall survival (OS), progression-free...
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PMID: 21990299
PDF is available here.
Abstract
We investigated whether serum amino acid profiles are a potentially useful biomarker in patients with renal cell carcinoma....
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PMID: 21849193
PDF is available here.
Abstract
We reviewed the slides of patients with clinical stage I nonseminomatous germ cell testicular tumors who underwent retroperitoneal lymph node dissection to evaluate the concordance between original and reviewed vascular invasion status, and other histological correlates.
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PMID: 21849196
PDF is available here.
Abstract
Serum C-reactive protein has been shown to have prognostic value in localized and metastatic renal cell carcinoma. However, the prognostic value of intratumor C-reactive protein remains unknown.
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PMID: 21849188
PDF is available here.
Abstract
The present study aims to investigate the expression and significance of the anti-apoptotic gene Bag-1 in colorectal cancer and to evaluate the relationship between the gene and the disease.
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PMID: 21809033
PDF is available here.
Abstract
The aim of this study was to compare the response to neoadjuvant taxanes and anthracyclines chemotherapy and survival in patients with triple-negative breast cancer (TNBC) and non-TNBC.
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PMID: 21830158
PDF is available here.
Abstract
The aim of this study was to examine the role of Ki-67, a cellular proliferation marker, in the prognosis of goblet cell appendiceal carcinoid tumor.
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PMID: 21824598
PDF is available here.
Ryu R Kanzaki,
Masahiko M Higashiyama,
Kazuyuki K Oda,
Ayako A Fujiwara,
Toshiteru T Tokunaga,
Jun J Maeda,
Jiro J Okami,
Koji K Tanaka,
Tatsushi T Shingai,
Shingo S Noura,
Masayuki M Ohue and
Ken K Kodama
Abstract
The outcomes after repeat pulmonary resection for colorectal cancer (CRC) and the factors associated with the prognosis of these patients remain uncharacterized.
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PMID: 21824604
PDF is available here.
Eszter E Székely,
Péter P Törzsök,
Péter P Riesz,
Anna A Korompay,
Attila A Fintha,
Tamás T Székely,
Gábor G Lotz,
Péter P Nyirády,
Imre I Romics,
József J Tímár,
Zsuzsa Z Schaff and
András A Kiss
Abstract
The members of the claudin family are major integral transmembrane protein constituents of tight junctions. Normal and neoplastic tissues can be characterized by unique qualitative and quantitative distribution of claudin subtypes, which may be related to clinicopathological features. Differential di...
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PMID: 21832144
PDF is available here.
Abstract
: To perform a systematic review and meta-analysis of the effects on the surviving twin of single fetal death comparing monochorionic to dichorionic twins to report the rates of co-twin death, preterm delivery, and neurologic morbidity in the surviving fetus.
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PMID: 21934458
PDF is available here.
Abstract
Functional mitral regurgitation (FMR) is a common finding in patients with heart failure (HF), but its effect on outcome is still uncertain, mainly because in previous studies sample sizes were relatively small and semiquantitative methods for FMR grading were used.
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PMID: 21807656
PDF is available here.
Abstract
Gene expression profiles of paired hepatocellular carcinoma (HCC) and adjacent noncancerous liver tissue samples revealed preferential expression of midkine in HCC. This finding suggested the clinical usefulness of midkine measurement in serum for monitoring HCC treatment response, recurrence, and pr...
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PMID: 21917682
PDF is available here.
Abstract
Ventilator-associated pneumonia (VAP) is the most common hospital-acquired, life-threatening infection. Poor outcome and health-care costs of nosocomial pneumonia remain a global burden. Currently, physicians rely on their experience to discriminate patients with good and poor outcome. However, stand...
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PMID: 21835904
PDF is available here.
Abstract
While determining the levels of specific antioxidants as antioxidant-barrier parameters in children with cancer may be valuable in predicting therapeutic responses as well as outcomes, additional studies are required. Pediatr Blood Cancer © 2011 Wiley-Liss, Inc.
Copyright © 2011 Wi...
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PMID: 21298774
PDF is available here.
Abstract
To ascertain if breast cancer subtypes had prognostic effect on breast cancer specific survival, distant metastases and local relapse rates in women affected by early stage breast cancer.
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PMID: 21824742
PDF is available here.
Abstract
To evaluate the feasability of immediate breast reconstruction (IBR) following mastectomy after neoadjuvant chemotherapy (NACT) and radiation therapy (RT) for operable invasive breast cancer (OIBC), in terms of incidence of local complications, locoregional control and survival.
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PMID: 21843920
PDF is available here.
V V Semiglazov,
W W Eiermann,
M M Zambetti,
A A Manikhas,
A A Bozhok,
A A Lluch,
S S Tjulandin,
M D MD Sabadell,
A A Caballero,
P P Valagussa,
J J Baselga and
L L Gianni
Abstract
To describe surgical outcomes in patients with HER2-positive locally advanced (LABC) or inflammatory breast cancer (IBC) participating in the NeOAdjuvant Herceptin (NOAH) study (ISRCTN86043495).
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PMID: 21843921
PDF is available here.
Abstract
The prognosis of gastrointestinal epithelial malignancies is derived from TNM staging. The nodal status has the most importance. It guides the subsequent adjuvant therapies and gives the oncologist outstanding information about the biology of disease. Recently, a growing number of publications seem t...
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PMID: 21843922
PDF is available here.
Abstract
We summarize those epilepsies, in which genetic testing has clinical significance. Different types of genetic tests are presented. Na-channel epilepsies include different clinical entities, the exact genetic diagnosis is relevant in the prognosis, genetic counseling, as well in the therapeutic decis...
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PMID: 22059368
PDF is available here.
Abstract
We investigated the value of circadian variations in high-sensitivity C-reactive protein (hs-CRP) levels in prediction of long-term cardiovascular events (CVE) in patients with stable coronary artery disease (CAD).
The study included 94 patients (70 men, 24 women; mean age 58±9 year...
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PMID: 21983767
PDF is available here.
Abstract
We could hope, in the 5 years to the emergence of an efficient treatment to slow the pace of renal failure in ADPKD.
Copyright © 2011 Elsevier Masson SAS. All rights reserved....
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PMID: 21964037
PDF is available here.
Abstract
We sought to determine the utility of this functional assay in assessing the risk of infection, rejection, and tumor recurrence in liver transplant recipients.
Immune function was determined by ImmuKnow assay that measures the amount of adenosine triphosphate (ATP) produced by CD4 (+...
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PMID: 21809031
PDF is available here.
Abstract
A 77 year-old male presented a locally advanced small cell anal cancer and simultaneous hepatic and glandular deposits. Due to metastatic disease, chemotherapy with carboplatin and etoposide was the primary choice of treatment. Small cell cancer of the gastrointestinal tract exerts an aggressive clin...
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PMID: 21936979
PDF is available here.
Abstract
Colorectal cancer is rare in younger age group. Most cases occur in the second decade of life and are clinically aggressive. The prognosis of these patients is generally poor. This is a retrospective study in which data of Indian patients was compared to standard literature.
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PMID: 21922876
PDF is available here.
Abstract
Evidence supporting the use of bioprostheses for heart valve replacement in young adults is accumulating. However, reoperation data, which may help guide clinical decision making in young patients, remains poorly defined in the literature.
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PMID: 21911822
PDF is available here.
Abstract
To investigate the prevalence, distribution, and prognostic role of BRAF mutations in a large cohort of white patients with non-small-cell lung cancer (NSCLC).
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PMID: 21825258
PDF is available here.
Abstract
This study assessed outcomes of individuals with advanced cancer who required admission to an intensive care unit (ICU) after referral for an early clinical trial because they did not respond to conventional therapy.
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PMID: 21844494
PDF is available here.
Abstract
Patients with head and neck cancer (HNC) are at high risk of death resulting from noncancer causes and second malignancies (ie, competing mortality). Variation in competing mortality risk complicates individual treatment choices and design and interpretation of clinical studies.
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PMID: 21844503
PDF is available here.
Abstract
Body size in early life has been associated with breast cancer risk. This may be partly mediated through the insulin-like growth factor (IGF) pathway. The authors assessed whether birth weight, body fatness at ages 5 and 10 years, and body mass index (BMI; weight (kg)/height (m)(2)) at age 18 years w...
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PMID: 21828371
PDF is available here.
Abstract
We show MMP-9 overexpression conferred a poor prognosis in 163 GBM patients. Furthermore, MMP-9 specific miRNA expression profile (14 positively and 31 negatively correlated miRNAs with MMP-9) was established via miRNA microarrays in 60 GBM samples. Among them, two miRNAs: miR-885-5p and miR-491-5p,...
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PMID: 21831363
PDF is available here.
Abstract
End-stage renal disease affects more than 70,000 persons in France, i.e., 1,1 per 1000 people, of whom 53% are on dialysis and 47% are living with a functioning graft. This prevalence increases about 4% per year. Overall, end-stage renal disease incidence tends to stabilize, excep...
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PMID: 21906908
PDF is available here.
Youngil Y Koh,
Hee Eun HE Lee,
Seock-Ah SA Im,
Se-Hyung SH Kim,
Tae Min TM Kim,
Sae-Won SW Han,
Do-Youn DY Oh,
Jee Hyun JH Kim,
Se-Hoon SH Lee,
Dong-Wan DW Kim,
Tae-You TY Kim,
Woo-Ho WH Kim,
Dae Seog DS Heo and
Yung-Jue YJ Bang
Abstract
We intended to find predictive markers in advanced gastrointestinal stromal tumor patients treated with sunitinib. Korean patients who received sunitinib after imatinib failure for advanced gastrointestinal stromal tumor were studied. Genotyping for KIT and PDGFRA were performed. An immunohistochemic...
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PMID: 21817899
PDF is available here.
Abstract
Hilar cholangiocarcinoma (HC) is invariably fatal without surgical intervention. The primary aim of the current study was to report overall survival and recurrence-free survival outcomes after surgical resection of HC.
Between December 1992 and December 2009, 85 patie...
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PMID: 21871986
PDF is available here.
Abstract
We conclude that MPP is associated with poor prognostic factors both in early and late stages in lung adenocarcinoma. Bcl-2 provides prognostic information independent from the MPP....
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PMID: 21851414
PDF is available here.
Abstract
Baseline patient-reported kidney cancer symptoms are linked to mPFS and mOS in a clear and interpretable way. These results support the evaluation of patient-reported symptoms at baseline in clinical trials and in clinical practice to measure symptom severity and potentially predict progression-free...
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PMID: 21476015
PDF is available here.
Abstract
We investigated the role of (18)F-FDG PET in patients with degenerative stenosis of the cervical spinal cord in relation to postsurgical outcome....
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PMID: 21852356
PDF is available here.
Abstract
We tested the hypothesis that circulating PICP and PIIINP are altered and may correlate with ventricular volume load and function in patients with repaired tetralogy of Fallot (TOF).
Serum PICP and plasma PIIINP levels were determined in 39 patients with repaired TOF aged 17.7 ± 4.1...
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PMID: 21884862
PDF is available here.
Abstract
We aimed to investigate the prognostic value of active plasma renin concentration (APRC) and prorenin in patients with HF treated with RAAS-blocking agents and its relationship with kidney function parameters.
One hundred clinically stable patients with HF, treated with RAAS-blocking...
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PMID: 21884865
PDF is available here.
Michiel M Rienstra,
Susan S Cheng,
Martin G MG Larson,
Elizabeth L EL McCabe,
Sarah L SL Booth,
Paul F PF Jacques,
Steven A SA Lubitz,
Xiaoyan X Yin,
Daniel D Levy,
Jared W JW Magnani,
Patrick T PT Ellinor,
Emelia J EJ Benjamin and
Thomas J TJ Wang
Abstract
We sought to investigate whether vitamin D status predisposed to the development of AF in a community-based sample.
We evaluated the relation between vitamin D status and development of AF in 2,930 participants of the Framingham Heart Study, Massachusetts, USA, without prevalent AF....
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PMID: 21884873
PDF is available here.
Abstract
High-degree atrioventricular block (HAVB) is a frequent complication in the acute stages of a myocardial infarction associated with an increased rate of mortality. However, the incidence and clinical significance of HAVB in late convalescent phases of an AMI is largely unknown. The a...
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PMID: 21884874
PDF is available here.
Abstract
We aimed to assess the incremental prognostic accuracy of eGFR(CKD-EPI) versus eGFR(MDRD) in subjects at increased risk for CV disease.
We performed a post hoc analysis of the VALIANT trial that enrolled 14,527 patients with acute myocardial infarction with signs and symptoms of hear...
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PMID: 21884875
PDF is available here.
Abstract
We sought to evaluate the prognostic performance of the CHADS(2) score for prediction of ischemic stroke/transient ischemic attack (TIA) in subjects with coronary heart disease (CHD) without atrial fibrillation (AF).
In 916 nonanticoagulated outpatients with stable CHD and no AF by b...
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PMID: 21884876
PDF is available here.
Abstract
Pediatric pulmonary arterial hypertension (PAH), whether idiopathic PAH (iPAH) or PAH associated with congenital heart disease (aPAH), carries high morbidity and mortality. Low pulmonary arterial capacitance (PAC), defined as right ventricular stroke volume/pulmonary artery pulse pre...
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PMID: 21884877
PDF is available here.
Abstract
Background Next to the school environment, the family and community environment are key for young people's behaviour and for promoting physical activity (PA). Methods A review of reviews was conducted, after which a literature search was conducted (in PubMed, Scopus and PsychInfo) from August 2007 (s...
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PMID: 21836175
PDF is available here.
Abstract
Background School-based interventions are thought to be the most universally applicable and effective way to counteract low physical activity (PA) and fitness although there is controversy about the optimal strategy to intervene. Objectives The objective of this review was to summarise recent reviews...
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PMID: 21836176
PDF is available here.
Yasumasa Y Shundo,
Tsuyoshi T Takahashi,
Toru T Itaya,
Hiroshi H Neyatani,
Hisao H Sugimura,
Yusuke Y Kita,
Hiroshi H Nogimura,
Ryo R Kobayashi,
Kazuya K Suzuki,
Kei K Shimizu,
Kazuhito K Funai and
Norihiko N Shiiya
Abstract
We present the clinical features of this malignant tumor. The male : female ratio was low. Many tumors were located peripherally, and the positive rate for carcinoembryonic antigen (CEA) was 54.8%; these clinical findings were similar to those of adenocarcinoma. On the other hand, many tumors had re...
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PMID: 21899122
PDF is available here.
Abstract
We have experience exciting developments regarding the approval of new treatment options but few patients are reaching sustained remission and refractory patients continue to be a problem. Thus, it is critical to understand how clinicians can decrease the risk of refractoriness by close monitoring d...
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PMID: 21570496
PDF is available here.
Abstract
The use of ultrasound is now widespread within the field of Emergency Medicine. The availability of lightweight and relatively cheap ultrasound devices has enabled clinicians to obtain more detailed information about the condition of acutely ill and injured patients than can be done...
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PMID: 21911912
PDF is available here.
Abstract
We decided to perform a prospective study of ARF in 180 pediatric patients admitted to our institute between August 2006 and March 2008. Our study included children, neonates 7.8%, <1 year 16.7%, 1-5 years 30.5% and >5 years comprised 52.8%. The male:female ratio was 2.3:1. Acute tubular necrosis re...
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PMID: 21912053
PDF is available here.
Abstract
The effect of potentially relevant genetic polymorphisms, CYP3A5 6986A>G and ABCB1 3435C>T, on Tacrolimus pharmacokinetics and graft clinical outcome was investigated in donor and recipient DNA samples from 209 kidney transplant patients.
The mean follow-up was 21.8 ...
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PMID: 21677300
PDF is available here.
Abstract
The effect of potentially relevant genetic polymorphisms, CYP3A5 6986A>G and ABCB1 3435C>T, on Tacrolimus pharmacokinetics and graft clinical outcome was investigated in donor and recipient DNA samples from 209 kidney transplant patients.
The mean follow-up was 21.8 ...
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PMID: 21677300
PDF is available here.
Abstract
The effect of potentially relevant genetic polymorphisms, CYP3A5 6986A>G and ABCB1 3435C>T, on Tacrolimus pharmacokinetics and graft clinical outcome was investigated in donor and recipient DNA samples from 209 kidney transplant patients.
The mean follow-up was 21.8 ...
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PMID: 21677300
PDF is available here.
Abstract
A 7.5-year-old male Persian cat with a history of asymptomatic hypertrophic cardiomyopathy was examined for severe lethargy and dyspnoea. Physical examination revealed bradycardia (60 beats/ minute), and ECG investigation revealed persistent atrial standstill that was most likely caused by atrial fib...
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PMID: 21939015
PDF is available here.