Abstract
We examined whether participants who failed to complete a simulated drive because of simulator sickness (dropouts) differed from those who completed the simulation (completers). Thirteen healthy older adult dropouts (mean age = 74.8 yr) and 12 comparable completers were compared on the following var...
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PMID: 20437916
PDF is available here.
Abstract
There were 3.2 billion airline passengers in 2006, compared to only 30 million in 1950. Intercontinental health disparities create a risk of pandemics such as SARS and so-called bird flu. Precautions are now being implemented both in airports and in aircraft, in addition to measures intended to prev...
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PMID: 20669640
PDF is available here.
Abstract
Microgravity affects the different organ systems to various degrees. In particular, a thoracocephalic fluid shift occurs through suppression of the hydrostatic gradient. Sensory conflict leads to space motion sickness, which is frequent early in the flight, and the musculo-skeletal system is perturb...
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PMID: 20669641
PDF is available here.
Abstract
Results from Experiment 1 indicated that VIMS severity increased as the pattern velocity increased from 0 dps to 34 dps. Results from Experiment 2 indicated that as the velocity of the rotating pattern increased, the slow-phase velocity of OKN and the severity of VIMS increased and peaked in the 60-...
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PMID: 20196298
PDF is available here.
Abstract
The uncoupled motion scenario led to significant cognitive aftereffects that cannot be solely attributed to motion sickness. These aftereffects lasted between 2 and 4 hr postexposure. The scenario generated some physiological aftereffects that lasted between 1 and 2 hr postexposure. However, it is l...
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PMID: 20196299
PDF is available here.
Abstract
Due to the small number of observations, no statistically significant correlations could be verified. Nevertheless, we had no drop out from selection due to motion sickness. DISCUSSION: The use of the after-flight motion sickness checklist seems to be effective. Further studies with a greater number...
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PMID: 19817241
PDF is available here.
Abstract
Plasma scopolamine concentrations, physiologic (heart rate and blood pressure), visual, and cognitive function parameters, and adverse effects were assessed before the first session (baseline) and after each 24-hour session. Visual function was tested again 24 hours after patch removal. Subjects als...
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PMID: 19698013
PDF is available here.
Abstract
The combination of modafinil and scopolamine (MS) allowed subjects to tolerate significantly more head tilts than placebo, but modafinil alone (MP) failed to differ significantly from placebo (DP). No significant cognitive performance decrements were observed among the three experimental conditions....
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PMID: 19653573
PDF is available here.
Abstract
No statistically significant reduction of seasickness symptoms was demonstrated between ondansetron treatment and placebo (a Wiker score of 2.69 +/- 1.78 and 2.81 +/- 1.97, respectively). There was no statistically significant difference in side effects or the results of the performance tests. CONCL...
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PMID: 19601507
PDF is available here.
Abstract
Nauseogenicity of visual OVAR peaks around 0.2 Hz, and increases with stimulus strength up to circa 45 degrees tilt, similar to real motion. With higher tilt angles, decreasing nauseogenicity suggests that the visual impact is partially quarantined because the motion would appear patently absurd and...
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PMID: 19522361
PDF is available here.
Abstract
There was a main effect of time, in that after the recommendations were implemented, there was a significant reduction in nausea, oculomotor, and total SSQ scores from the pre-study to the post-study. There was also a main effect of experience, as IP reported significantly greater SS than SP for the...
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PMID: 19522364
PDF is available here.
Abstract
Vestibular migraine (VM) designates recurrent attacks of vertigo that are caused by migraine. VM presents with attacks of spontaneous or positional vertigo, lasting seconds to days, accompanied by migrainous symptoms. Because headache is often absent during acute attacks, other migra...
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PMID: 19289221
PDF is available here.
Abstract
Vestibular migraine (VM) designates recurrent attacks of vertigo that are caused by migraine. VM presents with attacks of spontaneous or positional vertigo, lasting seconds to days, accompanied by migrainous symptoms. Because headache is often absent during acute attacks, other migra...
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PMID: 19289221
PDF is available here.
Abstract
Both migraine and vertigo are common in the general population with lifetime prevalences of about 16 % for migraine and 7 % for vertigo. Therefore, a concurrence of the two conditions can be expected in about 1.1 % of the general population by chance alone. However, recent epidemiological evidence s...
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PMID: 19225823
PDF is available here.
Abstract
To determine the influence of gravity during critical periods of development is important in the perspective of long-term spaceflight and exploration, data coming from this kind of studies providing insight into basical biological phenomena underlying the development of the nervous system and its pl...
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PMID: 18775454
PDF is available here.
Abstract
A total of 16 participants terminated the trial because of severe nausea, and the other 22 endured the full 25 min. Perceived motion sickness increased over time in both groups but less among those who endured the trial. Short-term memory performance decreased toward the end for those who terminated...
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PMID: 19634309
PDF is available here.
Abstract
Motion sickness is increased by roll oscillation used to compensate fully for low-frequency lateral oscillation. In general, when roll oscillation is combined with low-frequency lateral oscillation, motion sickness cannot be predicted from either the roll oscillation or the lateral oscillation alone...
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PMID: 19198194
PDF is available here.
Abstract
These pilot data suggest that rizatriptan does not consistently reduce visually-induced motion sickness in migraineurs. Rizatriptan may diminish motion sickness potentiation by cranial pain....
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PMID: 19680473
PDF is available here.
Abstract
After 2 G hypergravity load, rats ate a significant amount of kaolin, indicating that they suffered from motion sickness. The hypergravity-induced kaolin intake was suppressed by mepyramine, but not by terfinadine or zolantizine. This finding indicates that cerebral post-synaptic H1 but not H2 or pe...
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PMID: 18607976
PDF is available here.
Abstract
Our results show that patients do not suffer motion sickness or external surface instability on a moving couch....
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PMID: 19863229
PDF is available here.
Abstract
Maropitant (Cerenia), a selective neurokinin(1) receptor antagonist, was evaluated for efficacy and safety in prevention of vomiting due to motion sickness in dogs in two randomized clinical trials. One-hundred eighty-nine dogs with a history of motion sickness were enrolled at 26 veterinary clinics...
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PMID: 19000275
PDF is available here.
Abstract
With combined lateral and roll oscillation, the rate of increase in motion sickness is greater during periods of high-magnitude motion than during periods of low-magnitude motion. With motions having the same motion sickness dose value but different sequences of exposure, there were no significant d...
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PMID: 18998482
PDF is available here.
Abstract
The authors present some non-medical interventions that may be used to limit exposure to a number of disease processes. They then review the available information regarding the safety and efficacy of routine and travel-related vaccines as well as prophylactic medications for malaria, diarrhea, motio...
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PMID: 18760249
PDF is available here.
Abstract
On this premium expedition, the health problems encountered were largely similar to those reported for other expeditions. The most common problems included respiratory, gastrointestinal, dermatological conditions and minor trauma in descending order. As well as being part of the service provided to...
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PMID: 18760251
PDF is available here.
Abstract
OVAR was twice as nauseogenic as visual motion. Headache during visual motion suggests mechanisms in common with migraine. We hypothesize that subjects who fared better in the light used visual cues to resolve sensory conflict, whereas subjects who were equally susceptible in light and dark made poo...
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PMID: 18619124
PDF is available here.
Abstract
The overall AS incidence during Basic was 34.8%, without significant gender differences. However, within AS individuals, a significantly higher percentage of women were slow adaptors (12.5% of the whole female sample vs. 3.3% in men). AS overall affected the likelihood of reaching Basic certificatio...
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PMID: 18619127
PDF is available here.
Abstract
The present study characterizes the safety, pharmacokinetics, and anti-emetic effects of the selective NK-1 receptor antagonist maropitant in the cat. Safety of maropitant was determined following 15 days of subcutaneous (SC) administration at 0.5-5 mg/kg. Maropitant was well tolerated in cats at do...
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PMID: 18471143
PDF is available here.
Abstract
Dysfunction of the vestibular aqueduct is suggested by symptomatology characterised by: migraine-related vertigo, unstable or recurring oscillopsia, lowering of the vestibular evoked myogenic potential threshold, hypoacusis, anamnestic report of motion sickness, and nystagmus induced by mastoid vibr...
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PMID: 17908350
PDF is available here.
Abstract
This study identifies differences in the electroencephalogram (EEG) responses caused by individual sensitivity to simulator sickness. Simulator sickness was investigated by studying the changes in simulator sickness in two different subject groups (sick group and nonsick group). Subjective evaluatio...
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PMID: 18465429
PDF is available here.
Abstract
On this premium expedition, the health problems encountered were largely similar to those reported for other expeditions. The most common problems included respiratory, gastrointestinal, dermatological conditions and musculoskeletal conditions in descending order. As well as being part of the servic...
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PMID: 18486072
PDF is available here.
Abstract
Currently little is known about how adaptive responses to virtual environments are different between individuals who experience sickness related symptoms and those who do not. It is believed that sensory interactions between visually perceived self-motion and static inertial cues from vestibular and...
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PMID: 18359162
PDF is available here.
Abstract
Motion sickness incidence (42%) did not differ from that in studies using the corresponding physical moving room. Prior to motion sickness onset, the sick group exhibited changes in movement, relative to the well group, as predicted by the postural instability theory of motion sickness. Differences...
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PMID: 18516843
PDF is available here.
Abstract
Across conditions, the incidence of motion sickness ranged from 42% to 56%; incidence did not differ across conditions. During game play, head and torso motion differed between sick and well participants prior to the onset of subjective symptoms of motion sickness. CONCLUSION: The results indicate t...
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PMID: 18516842
PDF is available here.
Abstract
With rotational oscillation about an Earth-horizontal axis, there is a trend for motion sickness to increase with increasing motion magnitude. For the conditions investigated, similar motion sickness was caused by roll and pitch oscillation....
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PMID: 18457296
PDF is available here.
Abstract
Experiment 1: there was a significant effect of rotation on SR, and a significant rotation x position interaction such that the rotation-induced symptom increase was significantly higher in the supine compared to the upright position. In addition, there was a significant effect of gender, with women...
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PMID: 18457295
PDF is available here.
Abstract
During postoperative 24 hours period, 60 out of a total of 200 patients experienced nausea and vomiting. The factors associated with an increased risk of Postoperative Nausea and Vomiting (PONV) were gender (female odds ratio 3), patients with previous history of nausea and vomiting or motion sickne...
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PMID: 18460239
PDF is available here.
Abstract
Between November 2005 and June 2006, 1340, 2715, and 1035 patients were included in the control, DS and post-DS periods, respectively. As a result of mandatory data entry of risk factors, the percentage of high-risk PONV patients increased from 28% in the control period to 32% and 31% in the DS and...
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PMID: 18292437
PDF is available here.
Abstract
(1) Vasopressin induced gastric dysrhythmia and motion sickness-like signs (ANOVA, P < 0.001). (2) GES with short pulses or trains of short pulses was capable of preventing vasopressin-induced emetic response (P < 0.001), but did not normalize gastric dysrhythmia. (3) GES with long pulses or trains...
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PMID: 17721728
PDF is available here.
Abstract
We report that, even in the absence of a flavored solution, rats display conditioned gaping reactions during exposure to a distinctive context previously paired with a high dose of lithium (Experiment 1 with a distinctive odor and Experiment 3 without a distinctive odor), a low dose of lithium (Expe...
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PMID: 17897732
PDF is available here.
Abstract
The maximum ESDs during PCI for CTO exceed the thresholds for radiation skin injuries in many cases, although there are differences in the average maximum ESDs among institutions.
Copyright 2008 Wiley-Liss, Inc....
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PMID: 17932885
PDF is available here.
Abstract
Number correct and reaction times on the MAN task were negatively affected by each type of disorientation only when the task was performed in the presence of disorienting motion presented early in the experimental session. Later in the session, subjects learned to attain best performance levels irre...
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PMID: 18309907
PDF is available here.
Abstract
This study presents the neuro-otological findings of 523 patients attending a tertiary vestibular clinic with migraine- and nonmigraine-related dizziness. Subjects were categorized into one of 4 groups, definite migrainous vertigo, probable migrainous vertigo, vestibular disorder coexisting with mig...
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PMID: 18057875
PDF is available here.
Abstract
The rate of injury and illness was relatively low in the Newport-Bermuda race. Injuries to the upper extremities and lacerations were most common, and sea sickness was the most common illness. The majority of illness and injury can be initially managed onboard....
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PMID: 18513105
PDF is available here.
Abstract
We conclude that the transdermal scopolamine patch does not impair simulated ship handling....
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PMID: 19043911
PDF is available here.
Abstract
We speculate that fluctuating estrogen levels over the course of the menstrual cycle may influence the experience of or susceptibility to nausea and motion sickness during illusory self-motion and other nauseogenic contexts....
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PMID: 18485739
PDF is available here.
Abstract
These results suggest that HT velocity modulation could provide a practical means of incremental adaptation to CCS during SRC....
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PMID: 18776594
PDF is available here.
Abstract
We failed to find any evidence of transfer from the yaw plane to the pitch plane, suggesting that adaptation to cross-coupled stimuli is specific to the particular plane of head movement. The findings have applications for the use of centrifugation as a possible countermeasure for long duration spac...
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PMID: 18776596
PDF is available here.
Abstract
The novel method of 2-channel dual-pulse GES is capable of accelerating gastric emptying of solids and improving dysrhythmia and emetic responses induced by vasopressin. This new method of GES may have a potential for gastroparesis....
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PMID: 18154935
PDF is available here.
Abstract
The findings indicated that a functioning vestibular system is necessary for rotation-evoking pica in mice and thus pica can be a behavioral index of motion sickness in mice.
2008 S. Karger AG, Basel...
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PMID: 18391575
PDF is available here.
Abstract
We propose that our extensive experience with forward self-motion may form a neural expectancy (exposure-history) about the sensory inputs which typically accompany expanding flow. However, since backward self-motion is less common, there may be a weaker exposure-history for contracting flow, and as...
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PMID: 18605144
PDF is available here.
Abstract
We demonstrate that the reduction in T(VOR) produced by oral administration of 20 mg of baclofen causes a significant reduction in motion sickness susceptibility, tested with roll while rotating (RWR). These data show that motion sickness susceptibility can be pharmacologically manipulated with a GA...
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PMID: 18718351
PDF is available here.
Abstract
We used a score based on abovementioned symptoms as an index for the severity of MS in rodents. MS index was determined in 260 mice with this novel method. It was found that the distribution of MS index was normal (W=0.99; P=0.23. P>0.05 considered values' normal distribution). The effects of scopol...
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PMID: 17612582
PDF is available here.