Abstract
We hypothesized that unfavorable hemodynamic and oxygenation trends milder than catastrophic ones can be found intraoperatively in most patients with a pathological fracture and cancer-affected lungs.
Eleven patients with a femoral metastatic fracture or an impending fracture were studied in general...
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PMID: 20093982
PDF is available here.
Abstract
Treatment options in cases of severe craniofacial disorders with bone loss and tissue damage are usually limited to vascularized and nonvascularized tissue transfers, allografts, mechanical devices and, more recently, facial transplantation. Despite the therapies available, the demand for new approa...
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PMID: 21042127
PDF is available here.
Abstract
A 76-year-old woman with multiple bone metastases from lung adenocarcinoma was admitted due to a pathological femoral fracture. On the night after admission, her consciousness deteriorated rapidly and she developed progressive respiratory failure. Computed tomography of the chest revealed diffuse gr...
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PMID: 21066866
PDF is available here.
Abstract
Vertebroplasty (VP) and kyphoplasty (KP) are minimally invasive vertebral augmentation procedures for the treatment of fresh vertebral compression fractures (VCFs) associated with osteoporosis, trauma, malignant conditions, hemangiomas, and osteonecrosis. During these procedures, bone cement (e.g.,...
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PMID: 20802431
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Abstract
We report a case of spontaneous intrauterine fracture of the right tibia and fibula in an otherwise healthy fetus at 20 weeks of gestation. The fracture healed in utero in an abnormal position. Postnatal development of the baby was normal with spontaneous correction of the angulation, and no underly...
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PMID: 20389052
PDF is available here.
Abstract
We report the first case of Enterobacter aerogenes osteomyelitis of the right distal radius, complicated with a pathological fracture, in a 79-year-old man with diabetes, which was diagnosed by radiological, microbiological, and histopathological examinations. He recovered well after an 8-week cours...
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PMID: 20335785
PDF is available here.
Abstract
We have to pay attention to background diseases and life style of the patients....
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PMID: 20445286
PDF is available here.
Abstract
Recently, much of the attention given to bone-mineral disorder as the prognostic factor for mortality has focused on their links to chronic kidney disease (CKD-MBD; chronic kidney disease-mineral bone disease), especially in dialysis patients. Bone disease in dialysis patients showed heterogeneity c...
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PMID: 20445287
PDF is available here.
Abstract
Chronic kidney disease-mineral and bone disorder (CKD-MBD) is considered to be a systemic disorder that associated with fracture, cardiovascular disease, and mortality. Because the early initiation of appropriate therapy may prevent or ameliorate the mineral and bone disorder that developed in late...
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PMID: 20445276
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Abstract
Secondary osteoporosis is caused by various disorders, metabolic derangements, and drug administration, whose elimination as a cause for osteoporosis is necessary before establishing the diagnosis of primary osteoporosis. The underlying diseases or conditions are diversified, including those related...
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PMID: 20445274
PDF is available here.
Abstract
Calcium transfer from the mother to the infant during pregnancy and lactation plays an extremely important role in the bone health of the mother and neonate. Calcium aids in bone health through all ages but is especially crucial during pregnancy and lactation. Changes in the structure and metabolism...
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PMID: 20445278
PDF is available here.
Abstract
Patients with cancers such as breast or prostate cancer who have been treated with hormone deprivation therapies or anti-cancer agents for certain periods of time frequently manifest reduced bone mass or pathological fractures during their clinical course. These are likely due to an imbalance betwee...
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PMID: 20445280
PDF is available here.
Abstract
Development and maintenance of skeletal health is essential since the resultant effect of poor bone health is an increased risk of osteoporotic fracture. Osteoporosis is currently a major public health problem and with predicted demographic changes, its future health and economic impact is likely to...
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PMID: 21114195
PDF is available here.
Abstract
All patients were followed up from 4 to 7 years with an average duration of 75.3 months. The average neck-shaft angle was corrected from preoperative 75 degrees (range 55 degrees -100 degrees ) to postoperative 120 degrees (range 95 degrees -130 degrees ). The average extremity lengthening was 3.4 c...
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PMID: 19629503
PDF is available here.
Abstract
A number of factors need to be borne in mind in the planning and performance of instrumental fixation of the spine in patients with osteoporosis. Improved implant anchoring using special screws and cement augmentation can help to avoid implant dislocations. Nevertheless, particular attention should...
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PMID: 20358325
PDF is available here.
Abstract
The altered trabecular structure of the osteoporotic spine leads to an increased vulnerability of its biomechanical characteristics and reduction of load resistance. Therefore, any surgical procedure must account for these circumstances. In cement-augmented vertebrae, both the overall stability and...
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PMID: 20358324
PDF is available here.
Abstract
Osteoporosis is characterized by a reduction of bone mass and changes in bone micro-architecture. The resulting reduction in bone strength leads to the well recognized increase in the risk of fracture, particularly at the radius, hip, and spine. The treatment of osteoporotic fractures is challenged...
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PMID: 20333350
PDF is available here.
Abstract
Medical training therapy (MTT) plays a decisive role in maintenance and development of musculoskeletal health of humans in all phases of life. In childhood and adolescence it can contribute to the highest possible so-called peak bone mass and thus avoid or delay the appearance of osteoporosis for as...
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PMID: 20309519
PDF is available here.
Abstract
The clinical relevance of osteoporosis as a frequent systemic skeletal disease is to be found in fractures and their consequences. For prevention of these disease manifestations great importance must be attached to a safest possible diagnosis even before the occurrence of the first fracture and oste...
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PMID: 20309518
PDF is available here.
Abstract
Patients suffering from pain caused by osteoporotic fracture most want pain reduction and the ability to live independently. Age, co-morbidity and co-medication are individual factors which can interfere with drug therapy. Relevant factors for planning and applying drug therapy for pain reduction ar...
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PMID: 20225128
PDF is available here.
Abstract
Reduced bone quality due to osteoporosis poses a fundamental problem in spine surgery instrumentation. The consequences observed most often are insufficient implant anchoring and adjacent fractures. In cases of manifest osteoporosis, several modern anchoring possibilities are at our disposal that, t...
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PMID: 20232196
PDF is available here.
Abstract
Even in times of kyphoplasty and vertebroplasty, braces remain an efficient option in the treatment of osteoporotic hyperkyphosis due to imminent or manifest vertebral wedging with the obligatory pain and fracture risk of adjacent vertebraes. In the same fashion, acute osteoporotic fractures with co...
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PMID: 20358323
PDF is available here.
Abstract
Vertebral compression fractures are among the most common forms of manifestations of osteoporosis. Conservative treatment comprises adequate analgesia, osteoporosis medication and individualized physiotherapy or braces. Nevertheless, vertebral compression fractures frequently lead to persisting pain...
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PMID: 20232195
PDF is available here.
Abstract
A 68-year-old woman presenting with progressive paraparesis was diagnosed with an AVF involving a previously fractured L1 vertebral body on which feeders from multiple segmental arteries converged. The most distinctive feature in our patient was that the fistula was located in the ve...
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PMID: 19892811
PDF is available here.
Abstract
We also noted the findings in many patients with osteoporosis and hypothesized that it is not specific for malignant lesions. The aim of this study was to evaluate the prevalence of pedicle involvement in painful osteoporotic compression fractures and to determine whether the sign is specific for ma...
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PMID: 20019106
PDF is available here.
Abstract
In the distal section, bone volume was the greatest in the anterior part of the lateral condyle and the least in the posterior part of the lateral condyle. Cortical thickness in the distal section was the thickest in the posterior medial and the thinnest in the anterior aspect followed by lateral as...
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PMID: 19959376
PDF is available here.
Abstract
The 2000 NIH definition of osteoporosis may now call for revision in light of evidence accumulated through clinical studies in the last decade. Of note, as bone quality is now becoming available for evaluation, it is becoming clear that bone quality contributes to bone strength to a far greater degr...
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PMID: 20190360
PDF is available here.
Abstract
Since the aim of the treatment of osteoporosis is to prevent fractures, the first-line drugs must be chosen according to their antifracture efficacies. In postmenopausal women with osteoporosis, alendronate, risedronate, minodronate, and raloxifene are effective in preventing vertebral fractures, an...
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PMID: 20190370
PDF is available here.
Abstract
Osteoporosis is closely associated with lifestyle-related diseases, such as diabetes mellitus, hypertension, and hyperlipidemia. The meta-analysis data reveals that risk of hip fracture is higher in the patients with diabetes mellitus or hypertension compared with those without it. Bone quality more...
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PMID: 20190361
PDF is available here.
Abstract
The umbrella concept chronic kidney disease-mineral bone and disorders (CKD-MBD) has been developed these days, which includes vascular calcification, laboratory abnormalities, and bone abnormalities. Given the high prevalence of CKD stage 3 in the patients with osteoporosis and the high risk of fra...
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PMID: 20190367
PDF is available here.
Abstract
It is generally considered that drugs with different pharmacological actions are prescribed when combination therapy is undertaken. Vitamin D insufficiency or deficiency is prevalent in osteopenic and osteoporotic postmenopausal women. Combination therapy of raloxifene with other agents including vi...
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PMID: 20190371
PDF is available here.
Abstract
A number of drugs can have "side effects" on bone metabolism and formation, causing bone atrophy, impaired mineralisation, as well as osteonecrosis. In both clinical and general practitioner settings, these forms of bone damage have been hitherto considered as adverse drug side effects and have rece...
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PMID: 20146045
PDF is available here.
Abstract
To test the reliability and validity of questionnaires shortened from the National Eye Institute 25-item Vision Function Questionnaire (NEI VFQ-25).
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PMID: 20103058
PDF is available here.
Abstract
This study explored the feasibility and clinical outcome of kyphoplasty for the treatment of painful osteoporotic thoracolumbar burst fractures without neurological deficit. A total of 25 consecutive patients with painful type-A3 amyelic thoracolumbar fractures without neurological deficit were trea...
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PMID: 20192146
PDF is available here.
Abstract
We summarized the current understanding and therapy of bone metastasis in prostate cancer in mainly respect to Zoredronic acid use....
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PMID: 20118519
PDF is available here.
Abstract
The incidence of prostate cancer is increasing and the patients are generally of relatively advanced age. There has been an increase in the use of hormonal therapy in such cases. However, hormonal therapy for prostate cancer increases the risk of fracture. Bisphosphonates have been reported to preve...
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PMID: 20118508
PDF is available here.
Abstract
Microscopic hematuria is frequently seen during routine health check-ups. A recent epidemiological study has shown that the number of red blood cells in urine is inversely correlated with bone mineral density (BMD) in men and women over 50 years of age. This paper discusses mechanisms explaining the...
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PMID: 20118517
PDF is available here.
Abstract
We will summarize in vitro effects of AIs, especially androgenic effects of steroidal AIs upon human osteoblasts in order to further understand their effects on human skeletal systems....
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PMID: 20118510
PDF is available here.
Abstract
The mean DASH score reached 14 points, the modified Gartland/Werley score was 6.9. There was one loss of reduction on radiographic evaluation, which yielded to a dorsal osteosynthesis. Average postoperative radial inclination was 20.5 degrees (16-29 degrees) and the volar tilt 9.3 degrees (3-15 degr...
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PMID: 20135602
PDF is available here.
Abstract
Our study used a systematic process for patient selection and mutually exclusive categorization by SRE type and provides a per episode estimate of the inpatient financial impact of cancer related SREs assessed in this study from a third-party payer perspective....
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PMID: 21067255
PDF is available here.
Abstract
Treatment results of 32 patients with pathologic fractures of cervical vertebrae bodies were analyzed. Vertebral destruction was due to tumour metastases (18 patients), nonspecific spondylitis (12 patients) and fibrocystic displasia (2 patients). Myelopathy with local and radicular pain syndrome was...
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PMID: 20336046
PDF is available here.
Abstract
BACKGROUND: A study to evaluate the impact of a combined intervention (in-class and on-line training courses, a practicum and economic incentives) to improve anti-osteoporosis treatment and to improve recordkeeping for specific information about osteoporosis. METHODS/DESIGN: A before/after study wit...
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PMID: 20964817
PDF is available here.
Abstract
We measured serum 25-hydroxy-vitamin D, iPTH, total and ionised calcium, phosphate, and alkaline phosphatase in 129 Swiss children and adolescents with type 1 diabetes.
Of the 129 subjects 78 (60.5%) were vitamin D deficient, defined as a 25-hydroxy-vitamin-D level below 50 nmol/L. During the winter...
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PMID: 20853194
PDF is available here.
Abstract
The improved prognosis of cancer patients has led to an increased incidence of both bone metastases and (impending) pathological fractures. A solitary bone lesion seen on radiography should never be assumed to be a metastasis. Preoperative biopsy is necessary in patients with a known malignancy and...
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PMID: 21029490
PDF is available here.