Abstract
We hypothesize that a matured regional EGS service would show decreasing mortality and length of stay (LOS) over time.
We performed a retrospective study of a prospectively collected EGS registry data from 2004 to 2009. Patients were included if they had been discharged from the EGS...
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PMID: 21825946
PDF is available here.
Abstract
Recognition of trauma-induced coagulopathy by conventional coagulation testing (CCT) is limited by their slow results, incomplete characterization, and their poor predictive nature. Rapid thrombelastography (r-TEG) delivers a more comprehensive assessment of the coagulation system bu...
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PMID: 21825945
PDF is available here.
Abstract
These results are however likely to be somewhat overestimated, especially for non-fatal crashes. Multiple vehicle crashes were found to be largely unchanged. Reductions were found for some types of multiple vehicle crashes. Rear-end collisions are unchanged or may increase. Fatal crashes involving p...
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PMID: 21376913
PDF is available here.
Abstract
We highlight some recent data on the transcriptional regulation of hyaluronan synthase (Has1-3) expression and on the post-transcriptional control of hyaluronan synthase activity, which, in close association with the supply of the UDP-sugar substrates of hyaluronan synthase, adjust the rate of hyalu...
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PMID: 21362137
PDF is available here.
Abstract
Recombinant factor VIIa (rFVIIa) is approved for treatment of bleeding in patients who have hemophilia with inhibitors but has been applied to a wide range of off-label indications.
To estimate patterns of off-label rFVIIa use in U.S. hospitals.
Retros...
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PMID: 21502649
PDF is available here.
Veronica Yank,
C Vaughan Tuohy,
Aaron C Logan,
Dena M Bravata,
Kristan Staudenmayer,
Robin Eisenhut,
Vandana Sundaram,
Donal McMahon,
Ingram Olkin,
Kathryn M McDonald,
Douglas K Owens and
Randall S Stafford
Abstract
Recombinant factor VIIa (rFVIIa), a hemostatic agent approved for hemophilia, is increasingly used for off-label indications.
To evaluate the benefits and harms of rFVIIa use for 5 off-label, in-hospital indications: intracranial hemorrhage, cardiac surgery, trauma, l...
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PMID: 21502651
PDF is available here.
Abstract
To categorize national medical expenditures into patient-centered categories.
The 2007 Medical Expenditure Panel Survey (MEPS), a nationally representative annual survey of the civilian noninstitutionalized population.
Descriptive statistics categorizi...
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PMID: 21091472
PDF is available here.
Abstract
Caspase 1 activation by inflammasome complexes in response to pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) induces the maturation and secretion of the pro-inflammatory cytokines interleukin-1β (IL-1β) and IL-18. Recent reports have...
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PMID: 21350580
PDF is available here.
Abstract
We hypothesize a survival advantage in patients managed with DCR when compared with a historical cohort of patients. During the 2-year retrospective review, a 1-year period after institution of DCR was compared with a historical control. Resuscitation strategies were analyzed and stratified into eme...
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PMID: 21337881
PDF is available here.
Abstract
Most retrospective studies evaluating fresh-frozen plasma:packed red blood cell ratios in trauma patients requiring massive transfusion (MT) are limited by survival bias. As prospective resource-intensive studies are being designed to better evaluate resuscitation strategies, it is i...
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PMID: 21337871
PDF is available here.
Abstract
On January 12, 2010, a 7.0-magnitude earthquake struck Haiti, resulting in an estimated 222,570 deaths and 300,000 persons with injuries. The University of Miami Global Institute/Project Medishare (UMGI/PM) established the first field hospital in Port-au-Prince, Haiti, after the earthquake. To chara...
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PMID: 21209607
PDF is available here.
Abstract
Motor vehicle crashes are the leading cause of death in the United States among persons aged 5-34 years. Seat belts have been shown to be the most effective method for reducing injuries among adults in the event of a crash.
CDC used 2009 data from the National Electronic Injury Surveillance System--...
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PMID: 21209609
PDF is available here.
Abstract
We investigated the incidence of hospital utilization for injuries and compared poisoning with other forms of injury. Previous studies have suggested poison control centers reduce health-care costs by decreasing hospital utilization.
We conducted a one-year retrospective study involv...
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PMID: 21337934
PDF is available here.
Abstract
We provided national prevalence estimates for selected health-risk behaviors for Asian American and Pacific Islander high school students separately, and compared those prevalence estimates with those of white, black, and Hispanic students.
We analyzed data from the Youth Risk Behavi...
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PMID: 21337930
PDF is available here.
Abstract
I trauma center between January 1, 2006, and December 31, 2007. The outcome of interest was directness of transport to a Level I trauma center. A propensity score analysis was used to identify demographic, clinical, distance, and other injury scene-related variables associated with the probability o...
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PMID: 20526210
PDF is available here.
Abstract
Previous work has suggested that insurance status, gender, and ethnicity all have an independent association with mortality after trauma. The purpose of this study is to investigate whether these factors exerted survival impact that could be observed throughout the hospital stay.
Using the National...
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PMID: 21217490
PDF is available here.
Abstract
We conclude that the FREE can provide meaningful data in difficult to image critically ill trauma patients....
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PMID: 21217482
PDF is available here.
Abstract
We hypothesized that initial studies suffer from survival bias because they do not consider early deaths secondary to uncontrolled exsanguinating hemorrhage. To help resolve this controversy, we evaluated the temporal relationship between blood product administration and mortality in civilian trauma...
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PMID: 21217487
PDF is available here.
Elliott R Haut,
Eric B Schneider,
Amar Patel,
Michael B Streiff,
Adil H Haider,
Kent A Stevens,
David C Chang,
Melanie L Neal,
Christopher Hoeft,
Avery B Nathens,
Edward E Cornwell,
Peter J Pronovost and
David T Efron
Abstract
We hypothesized that trauma surgeons have varying opinions regarding duplex ultrasound screening for DVT in asymptomatic trauma patients, which result in varying practice patterns.
We conducted two web-based surveys regarding the use of duplex ultrasound screening for DVT in asymptomatic trauma pati...
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PMID: 21217477
PDF is available here.
Abstract
The Centers for Disease Control recently updated the National Trauma Triage Protocol. This field triage algorithm guides emergency medical service providers through four decision steps (physiologic [PHY], anatomic [ANA], mechanism, and special considerations) to identify patients who would benefit f...
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PMID: 21217479
PDF is available here.
Abstract
We propose a revision of the original 1989 renal organ injury system established by the American Association for the Surgery of Trauma based on our institution's>25-year longitudinal experience. Our goal is to expand the current grading system to include segmental vascular injuries and ureteral pelv...
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PMID: 21217478
PDF is available here.
Abstract
We report the use of a new P2Y12 point-of-care assay (VerifyNow; Accumetrics, San Diego, CA) to determine the magnitude of platelet inhibition in trauma patients using clopidogrel.
Trauma patients in 2009 were queried for clopidogrel use by prehospital personnel and the trauma team. Blood was obtain...
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PMID: 21217483
PDF is available here.
Abstract
Benefits of high ratios of fresh frozen plasma (FFP) to packed red blood cells (pRBC) in massively transfused trauma patients have been reported previously. This study aimed to assess the effect of higher FFP:pRBC ratios on outcome in patients receiving less than massive transfusion during acute tra...
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PMID: 21217485
PDF is available here.
Abstract
We report preliminary findings on the effects of different FFP:PRBC ratios on coagulation.
This is a prospective observational cohort study of trauma patients requiring >4 U of PRBCs. Blood was drawn before and after each 4-U PRBC interval for prothrombin time and analysis by rotational thromboelast...
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PMID: 21217486
PDF is available here.
Abstract
By the principles of Tactical Combat Casualty Care, battlefield casualties are preferentially triaged on the basis of pulse character and mental status. A weak or absent palpable pulse correlates with a systolic blood pressure (SBP) of ≤ 100 mm Hg. Furthermore, the motor component of the Glasgow C...
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PMID: 21146011
PDF is available here.
Abstract
Level III trauma centers are an effective component of a healthy trauma system. This study examined the effectiveness over time of a Level III trauma center in a predominately rural region.
For analysis, the data were divided into 2 equal time spans: an early period (1997-2002) and a late period (20...
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PMID: 21146013
PDF is available here.
Abstract
The controlled cortical impact (CCI) model is widely used in many laboratories to study traumatic brain injury (TBI). Although external impact parameters during CCI tests could be clearly defined, little is known about the internal tissue-level mechanical responses of the rat brain....
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PMID: 20372960
PDF is available here.
Abstract
Neglected malignant ulcerating tumours often result from failure to seek medical attention, even when the advancing tumour is visible to the patient and their friends and families. Although the appropriate wound treatment procedures are the same as for non-neglected malignant wounds, clinicians must...
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PMID: 21160442
PDF is available here.
Abstract
We review the goals of a hospital-based CPSP, briefly review one American Academy of Pediatrics (AAP) Policy Statement, describe how one CPSP functions, and provide resources to those interested in program development....
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PMID: 21197870
PDF is available here.
Abstract
We seek to evaluate whether Web-based didactics result in similar knowledge improvement and retention of basic ultrasonographic principles and the Extended Focused Assessment with Sonography for Trauma (EFAST) compared with the traditional method.
Physicians from 2 German emergency departments were...
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PMID: 20538370
PDF is available here.
Abstract
Little is known about how to remedy the unmet mental health needs associated with major terrorist attacks, or what outcomes are achievable with evidence-based treatment. This article reports the usage, diagnoses and outcomes associated with the 2-year Trauma Response Programme (TRP) for those affect...
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PMID: 20178677
PDF is available here.
Abstract
We retrospectively reviewed a cohort of severely injured trauma patients (Injury Severity Score ≥ 16) admitted to a Level I trauma center with available ROTEM measurements on hospital admission during a 1-year study period. Patients with isolated head injury (Abbreviated Injury Scale head ≥ 3 an...
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PMID: 21150521
PDF is available here.
Abstract
We have sought to examine the fate of trauma patients transferred after first echelon hospital evaluation and treatment.
All trauma patients transferred (referred group) to a Pennsylvania Level I TC located in a geographically isolated and rural setting during a 68-month period were retrospectively...
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PMID: 20495488
PDF is available here.
Abstract
We examined prevalence rates of both posttraumatic stress disorder (PTSD) and major depression at 6 and 12 months in a sample of 677 individuals experiencing different types of trauma who were representative of physical trauma survivors hospitalized in Los Angeles County trauma centers. Demographic...
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PMID: 20693915
PDF is available here.
Abstract
The purpose of a scaling system for specific injuries is to provide a common language to facilitate the clinical decisions and the investigative basis for this decision making. This brief overview describes the evolution of the Organ Injury Scaling (OIS) system developed by the American Association...
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PMID: 21150537
PDF is available here.
Abstract
End-of-life care for trauma patients requires unique practice guidelines because it is fraught with difficulties not encountered in end-of-life care for terminally ill patients. The purpose of this project was to analyze survey information from nurses and physicians regarding preferences for end-of-...
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PMID: 21150531
PDF is available here.
Abstract
Health-related quality of life (HRQL) is subjective concept and, therefore, should be captured directly from the patient. However, proxy reporting of HRQL is widespread, particularly in pediatric studies where children have been considered unreliable respondents. This study assessed the level of agr...
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PMID: 21150532
PDF is available here.
Abstract
We compared in-hospital mortality among patients who received exclusively old versus fresh RBC units during the first 24 hours of hospitalization.
Patients admitted to a Level I trauma center between January 2000 and May 2009 who received ≥ 1 unit of exclusively old (≥ 14 days) vs. fresh (< 14 d...
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PMID: 21150522
PDF is available here.
Abstract
We investigated how switching from high (21%) to low (2%) oxygen levels directly affects cultured skin myofibroblasts, essential cells for the normal wound repair process. Myofibroblast differentiation and function were assessed by quantifying α-smooth muscle actin expression and cell contraction i...
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PMID: 20686497
PDF is available here.
Abstract
We are reminded that correcting wound tissue hypoxia is critical for the tissue's response to other therapeutic interventions....
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PMID: 21068734
PDF is available here.
Abstract
To characterize features of diagnosis, treatment, and outcome in horses with foreign bodies, exclusive of enteric, inhaled, and foot-penetrating foreign bodies.
Retrospective case series.
37 horses with foreign bodies.
The incidence of equine foreign bodies from 1990 through 2005 was determined by r...
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PMID: 21073389
PDF is available here.
Abstract
We used the National Young Driver Survey (NYDS), a nationally representative (N=5665) cross-sectional study of adolescent driving behavior, to examine potential psychosocial correlates of cell phone use while driving (CPWD). Results indicated that stronger beliefs about the advantages of abstention...
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PMID: 20728605
PDF is available here.
Abstract
We apply a random parameters ordered probit model to explore the influence of speed and traffic volume on the injury level sustained by vehicle occupants involved in accidents on the A4-A86 junction in the Paris region. Results indicate that increased traffic volume has a consistently positive effec...
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PMID: 20728609
PDF is available here.
Abstract
We refer to this magnitude as injury severity. A decrease in the injury severity of a driver is interpreted as an improvement in the crashworthiness of their car; similarly, a decrease in the injury severity of the opponent driver is regarded as an improvement in aggressivity. Data have been extract...
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PMID: 20728610
PDF is available here.
Abstract
A traffic encounter between individual road users is a process of continuous interplay over time and space and may be seen as an elementary event with the potential to develop into an accident. This paper proposes a framework for organising all traffic encounters into a severity hierarchy based on s...
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PMID: 20728612
PDF is available here.