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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Endocrine Gland Neoplasms (9):
Recent article
Endocrine Gland Neoplasms
New England Journal of Medicine (364)12 2011
Abstract
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Abstract
Presentation of techniques and procedures for regional chemotherapy in the treatment of unresectable liver metastases from different primary tumors as a modality of interdisciplinary therapy management. Such transarterial therapy methods include hepatic arterial infusion (HAI), transarterial chemoem...
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PMID: 21113865
PDF is available here.
PDF is available here.
American Surgeon (76)11 2010
Abstract
Discovery medicine (10)53 2010
Abstract
We discuss the role of telomerase in normal, benign, and cancerous endocrine tissues....
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PMID: 21034675
PDF is available here.
PDF is available here.
Abstract
CTGF IR was present in >50% of tumor cells in all 42 ileal carcinoids and in 2 out of 14 endocrine pancreatic tumors, 4 out of 6 rectal carcinoids, and 1 out of 5 lung carcinoids. Tumors with abundant CTGF expression also displayed α-SMA IR in stromal fibroblast-like cells, whereas other endocrine...
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PMID: 20660557
PDF is available here.
PDF is available here.
Endocrine Reviews (31)4 2010
Abstract
We will address the genetic alterations of TKRs, the rationale for utilizing TKIs for endocrine tumors, and current information on tumor and patient responses to specific TKIs. We will also discuss the adverse effects related to TKI treatment and the mechanisms involved. Finally, we will summarize t...
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PMID: 20605972
PDF is available here.
PDF is available here.
Abstract
Abstract
A 72-year-old woman presented at our hospital with a 1-year history of intermittent right lower abdominal pain. Colonoscopic examination revealed a submucosal tumor with a pitted surface in the terminal ileum. Histopathological diagnosis of the carcinoid tumor was made following biopsy. Blood seroto...
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PMID: 20632686
PDF is available here.
PDF is available here.
Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia (145)2 2010
Abstract
Skin serves as a window to the wellbeing and disease in a person. The recognition of cutaneous markers of endocrine neoplasia can allow for the early diagnosis of tumors, for early treatment and ultimately prevention of morbidity and mortality secondary to malignancy. The following review outlines t...
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PMID: 20467397
PDF is available here.
PDF is available here.
Endocrine-Related Cancer (17)1 2010
Abstract
We will highlight microRNAs of potential relevance to endocrine tumors and hormone-dependent cancers. Through this overview of how microRNAs regulate multiple targets and entire pathways, we will provide insight into the potential to develop new molecular microRNA-targeted therapies for endocrine tu...
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PMID: 19843580
PDF is available here.
PDF is available here.
Endocrine-Related Cancer (17)1 2010
Abstract
Abstract
Functional information provided by PET tracers together with the superior image quality and the better data quantification by PET technology had a changing effect on the significance of nuclear medicine in medical issues. Recently introduced hybrid PET/CT systems together with the introduction of no...
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PMID: 20089377
PDF is available here.
PDF is available here.
Acta Cytologica (54)5 Suppl 2010
Abstract
We report a rare variant of PENs called a lipid-rich variant and elaborate on its cytologic features with reference to fine needle aspiration (FNA).
The patient was a 74-year-old man with a 2.1-cm mass in the body of the pancreas. The FNA showed numerous cells with vacuolated, foamy cytoplasm, mostl...
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PMID: 21053550
PDF is available here.
PDF is available here.
Neuroendocrinology (91)2 2010
Abstract
We decided to comprehensively characterize the chromosomal constitution of BON-1 by applying conventional GTG-banding, spectral karyotyping (SKY), comparative genomic hybridization (CGH) and fluorescence in situ hybridization (FISH). BON-1 cells proved to be hyperdiploid containing a modal chromosom...
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PMID: 19887762
PDF is available here.
PDF is available here.
Acta Oncologica (49)1 2010
Abstract
Abstract
We describe how PET, using 18F-FDG and other radiopharmaceuticals can be useful in the diagnosis and management of a wide range of endocrine tumors....
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PMID: 19820296
PDF is available here.
PDF is available here.
Abstract
We report a case of a 40-year-old Caucasian man with a sporadic form of CNC.
This is a clinicopathologic description and molecular biological study with an emphasis on histopathologic findings.
The patient presented with multiple cutaneous myxomas, cardiac myxomas, an...
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PMID: 19539840
PDF is available here.
PDF is available here.
Abstract
Thyroid nodules are uncommon but malignant in as many as 27% of patients. Fine needle aspiration should be considered in adolescents, in which accuracy is as high as 90%; surgical resection should be undertaken in all preadolescents (<13 years) with a thyroid nodule. Prognosis for most primary thyro...
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PMID: 19421059
PDF is available here.
PDF is available here.
Abstract
We show that the combined treatment of pancreatic endocrine tumour cell lines with TSA and the DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine (DAC) determines a strong synergistic inhibition of proliferation mainly due to apoptotic cell death. Proteomic analysis demonstrates that the modulat...
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PMID: 19294695
PDF is available here.
PDF is available here.
Survival and prognostic factor analysis in patients with metastatic pancreatic endocrine carcinomas.
Abstract
Median overall survival is 70 months (5.8 years) among patients with metastatic PECAs. This prolonged survival duration may reflect the impact of multimodality treatments. Tumor grade (low vs intermediate grade) represents a highly significant prognostic factor....
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PMID: 19066493
PDF is available here.
PDF is available here.
Abstract
A 65-year-old Japanese male was referred to our hospital for evaluation of a main pancreatic duct obstruction. Two months previously, he had suffered an attack of acute pancreatitis that was resolved with conservative treatment. Dynamic contrast-enhanced study by multidetector row computed tomograph...
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PMID: 19400556
PDF is available here.
PDF is available here.
Abstract
Der Chirurg (80)2 2009
[Indication and performance of endocrine surgery. The significance of molecular genetic examination]
Abstract
We discuss the current possibilities for molecular genetic determination of disease-specific mutations (germline and tumor DNA) and their effect on surgical procedure....
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PMID: 19096808
PDF is available here.
PDF is available here.
Abstract
We report a case of endocrine cell carcinoma in the sigmoid colon with inferior mesenteric vein (IMV) tumor embolism. A 79-year-old woman was admitted to our hospital with narrowing of the stools. We performed colonoscopy, computed tomography and positron emission tomography, which disclosed sigmoid...
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PMID: 19132778
PDF is available here.
PDF is available here.
Acta Cytologica (53)2 2009
Abstract
We discuss the diagnostic pitfalls and differential diagnoses of the metastatic pancreatic MCC, highlighting the importance of thorough clinical history, attention to cytologic detail and corroborating immunohirtochemistry in arriving at the correct diagns. This is the first case ofa metastatic panc...
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PMID: 19365981
PDF is available here.
PDF is available here.
Abstract
We have used to study families with Catney complex and Micronodular adrenocortical hyperplasia. In addition, we discuss practical clues and tips aiming at extending applications and improving performance....
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PMID: 19763502
PDF is available here.
PDF is available here.
Abstract
Median post-operative follow-up was 47 months (4-162). In the adjuvant CT group, all patients except one received the 4 cycles. Two patients had grade 3-4 toxicity, including 1 febrile neutropenia resulting in death. Recurrence occurred in 43% and 65% of patients in the observation and adjuvant CT g...
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PMID: 19081477
PDF is available here.
PDF is available here.
Endokrynologia Polska (60)1 2009
Abstract
We demonstrated that antioxidants, such as pineal hormone - melatonin, indole-3-propionic acid (IPA) (a compound chemically and physically similar to melatonin) and antythyroid drug - propylthiouracil (PTU), produce distinct protective effects against lipid peroxidation due to KBrO(3) in the thyroid...
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PMID: 19224504
PDF is available here.
PDF is available here.
Hepato-gastroenterology (56)93 2009
Abstract
Twenty eight patients (12 men) were selected. Median age was 48 (range, 23-79) yrs. All resection of metastasis were performed during the same procedure of primary tumour resection. There were 14 DT and 14 non functional DP tumours. For 28 patients, the only factor of recurrence was endocrine pancre...
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PMID: 19760966
PDF is available here.
PDF is available here.
La Tunisie medicale (86)12 2008
Abstract
Clinical Cancer Research (14)23 2008
Abstract
The recently suggested TNM staging system emerged as a useful clinical tool....
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PMID: 19047107
PDF is available here.
PDF is available here.
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology (19)3 2008
Abstract
As with most endocrine tumors, the malignant potential depends on evidence of local or distant invasion (metastasis), so it is important to differentiate synchronous/metachronous endocrine tumors from their metastases. A 90-year-old man was operated due to tumor of the ampulla of Vater. As the surgi...
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PMID: 19115157
PDF is available here.
PDF is available here.
Abstract
All MSPCs displayed serotonin and strong TK expression. TK-IR was also seen in all serotonin-producing lung and appendix carcinoids. None of the other tumors examined contained TK-IR cells. Concentrations of P-TK, P-CgA, and U-5HIAA were elevated in patients experiencing daily episodes of either flu...
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PMID: 18524798
PDF is available here.
PDF is available here.
Abstract
The availability of PET/CT examinations in Hungary has significantly improved in the past few years. In the three Hungarian centres approximately 10,000 examinations can be performed yearly, which are financed by the national healthcare system. The PET/CT technique using FDG has become an efficient...
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PMID: 18799405
PDF is available here.
PDF is available here.
Abstract
We recommend bone staging with SRS and spine MRI in all patients with bronchial-thymic or unknown primary WD-GEP-EC. In case of duodeno-pancreatic or ileal primary, bone imaging may be restricted to patients with liver metastases....
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PMID: 18522978
PDF is available here.
PDF is available here.
Archives de Pédiatrie (15)5 2008
Abstract
Endocrine-Related Cancer (15)2 2008
Abstract
The 'endocannabinoid system', comprising the cannabinoid CB1 and CB2 receptors, their endogenous ligands, endocannabinoids and the enzymes that regulate their biosynthesis and degradation, has drawn a great deal of scientist attention during the last two decades. The endocannabinoid system is involv...
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PMID: 18508995
PDF is available here.
PDF is available here.
Endocrine-Related Cancer (15)2 2008
Abstract
Pancreatic endocrine tumors (PETs) are uncommon tumors with an annual incidence <1 per 100 000 person-years in the general population. The PETs that produce hormones resulting in symptoms are designated as functional. The majority of PETs are non-functional. Of the functional tumors, insulinomas are...
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PMID: 18508996
PDF is available here.
PDF is available here.
Minerva endocrinologica (33)2 2008
Abstract
The role of PET in the assessment of endocrine tumours has been, until recently, restricted to the use of (18)F-fluoro-deoxy-D-glucose ((18)F-FDG). Being a marker of metabolically active lesions that show high grading and low differentiation, FDG is not ideal for this purpose since the majority of e...
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PMID: 18414356
PDF is available here.
PDF is available here.
Abstract
TACE with DEBs is well tolerated and appears effective. A comparative study with a standard TACE or transarterial embolization regimen is warranted to define the best protocol for transarterial treatment of GEP liver metastases....
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PMID: 18503899
PDF is available here.
PDF is available here.
Molecular and Cellular Endocrinology (286)1-2 2008
Abstract
Somatostatin receptors (sst), somatostatin (SS) and cortistatin (CST) are widely expressed in the various systems in the human and rodent organisms and are "responsible" for maintaining homeostasis, which is essential for survival. Because of their broad expression pattern sst, SS and CST interactio...
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PMID: 17942217
PDF is available here.
PDF is available here.
Abstract
Tumor necrosis factor alpha converting enzyme (TACE) mediates shedding of human epidermal growth factor receptor-4 (HER4). Recent data suggest that released HER4 intracellular domain (4ICD) induces apoptosis in breast cancer. TACE expression, as measured by immunohistochemical analysis, was observed...
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PMID: 18426733
PDF is available here.
PDF is available here.
Abstract
Lancet Oncology (9)5 2008
Abstract
As the molecular basis of disease continues to be elucidated, familial cancer syndromes, which consist of a range of neoplastic and non-neoplastic features, are emerging. The usual pathway of referral to a genetics clinic or familial cancer centre is via an oncologist, when high-risk features that s...
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PMID: 18452857
PDF is available here.
PDF is available here.
Abstract
We have established a pancreatic cancer tissue bank with standardized procedures for collection of biospecimens along with a comprehensive multidisciplinary clinical database. The integrated biospecimen bank and clinical database for pancreatic cancer described here can serve as a model from which o...
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PMID: 18256882
PDF is available here.
PDF is available here.
Abstract
The relationship between environmental factors and health is well known. Rural environmental influences on reproductive health have been properly proved, both in animals and humans. In Latin America, few studies have been conducted in this area. The current project is based on the description of rel...
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PMID: 18392355
PDF is available here.
PDF is available here.
Annals of Surgery (247)4 2008
Abstract
This 2-step surgery approach enables complete resection with no mortality, acceptable morbidity, and good long-term survival in selected patients with synchronous bilobar LM from DET....
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PMID: 18362629
PDF is available here.
PDF is available here.
Annales d'Endocrinologie (69)2 2008
Abstract
Annales d'Endocrinologie (69)2 2008
Abstract
There is considerable interest in the application of DNA microarrays to the pathologic evaluation of endocrine neoplasms. Improvements in tumor classification and prognostication, prediction of response to therapy, and comprehensive assessment of tumoral hormone production represent the major antici...
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PMID: 18423557
PDF is available here.
PDF is available here.
Abstract
We briefly described microRNA biogenesis, function and the principal approaches for studying the function of microRNAs (miRNA) in solid cancers. There are currently hundreds of confirmed miRNAs in humans, and computational predictions suggest that the total count might be more than thousand. The reg...
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PMID: 18296065
PDF is available here.
PDF is available here.
Abstract
The extended microsatellite panel is qualified to detect MSI in PCC. Nine percent of MSI-positive cases would have not been noticed by the use of the reference panel alone. PCCs are characterized by low frequency MSI pointing to failures in factors involved in DNA replication....
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PMID: 17828419
PDF is available here.
PDF is available here.
Abstract
We present a case of a large maxillary sinus tumor in a 6-year-old boy, immunohistologically indistinguishable from a malignant melanoma, that led to the diagnosis of Carney complex. The Carney complex is an autosomal dominant disorder characterized by mucocutaneous pigmented lesions and neoplasia o...
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PMID: 18082273
PDF is available here.
PDF is available here.
Abstract
OBJECTIVE: Imaging of endocrine neoplasms often involves a combination of anatomic and functional techniques including sonography, CT, MRI, and scintigraphy. Recent technologic advances have enabled hybrid imaging using SPECT-CT, which combines anatomic and functional techniques to allow accurate lo...
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PMID: 18287457
PDF is available here.
PDF is available here.
Abstract
The lack of tracer uptake at the (111)In-pentetreotide scintigraphy seemed to be a poor prognostic factor (P = .007) for overall survival by Kaplan-Meier test and in multivariate analysis; age and absence of clinical secretory syndrome also seemed to be poor prognostic factors. The tracer uptake (po...
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PMID: 18281671
PDF is available here.
PDF is available here.
Abstract
Abstract
We also discuss what steps have to be taken to develop a better immunotherapy in endocrine tumors....
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PMID: 18283626
PDF is available here.
PDF is available here.
Abstract
We report a case of endocrine carcinoma of the sigmoid colon. A 71-year-old man was admitted to our hospital because of constipation and bloody stool. Colonoscopy showed a mass lesion with irregular ulceration in the sigmoid colon. He was given a diagnosis of the poorly differentiated adenocarcinoma...
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PMID: 18250594
PDF is available here.
PDF is available here.
Annales de Pathologie (28)1 2008
Abstract
Neuroendocrinology (87)1 2008
Abstract
Abstract
In vitro studies suggested that the incorporation of [(18)F]FCH in endocrine tumor cell lines was related to their growth capacities; however, in vivo studies conducted in an endocrine xenografted animal model showed an uptake of [(18)F]FCH in hepatic metastases lower than that in normal liver cells...
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PMID: 18158951
PDF is available here.
PDF is available here.