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Parathyroid Diseases (3):
Recent article
Parathyroid Diseases
Abstract
Glial cells missing 2 (Gcm2) is a master regulatory gene of parathyroid gland development, and it is exclusively expressed in the parathyroid gland. Diagnostic application of anti-Gcm2 antibody has not been reported yet. In this study, a total of 58 cases of parathyroid lesions including 40 adenomas...
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PMID: 21164298
PDF is available here.
PDF is available here.
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Abstract
Brown tumors are equally found in secondary and primary hyperparathyroidism. Craniofacial brown tumors involve the orbit, usually because of the osteodystrophy process that involves the maxilla and paranasal sinuses. The lesions do not necessarily need to be excised and may regress spontaneously aft...
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PMID: 20305510
PDF is available here.
PDF is available here.
Ukrainskij biokhimicheskij zhurnal/Ukrayins'kij biokhimichnij zhurnal/Ukrainian biochemical journal (82)2 2010
Abstract
B-, H- and L-catepsine-like activity regarding Na-benzoyl-D,L-arginine-4-nitroanilide, L-leucine-4-nitroanilide and azocasein was studied in the blood plasma of patients with different diseases of thyroid, parathyroid and adrenal glands. It has been shown that the high H- catepsine-like activity con...
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PMID: 20684245
PDF is available here.
PDF is available here.
Abstract
The knowledge of parathyroid and thyroid anatomy helps a surgeon to localize important details and lessen complications, especially laryngeal palsy and hypoparathyroidism. The ligament of Berry and tuberculum Zuckerkandl cover the recurrent laryngeal nerve in the upper part of the thyroid lobes. The...
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PMID: 20402038
PDF is available here.
PDF is available here.
Abstract
Il Giornale di chirurgia (31)6-7 2010
Abstract
We find also in nonsyndromic scenarios. In our study, were considered the latter. Between 2003 and 2008 in our Division of General Surgery 61 patients underwent operation for hyperparathyroidism, 13 for primary, 41 secondary and 7 tertiary. Twenty-six of these patients underwent also total thyroidec...
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PMID: 20646378
PDF is available here.
PDF is available here.
Sao Paulo Medical Journal (127)6 2009
Abstract
CONTEXT: Parathyroid cysts are rare clinical and pathological entities, with less than 300 cases reported. The inferior parathyroid glands are most commonly involved, with left-side predominance. Parathyroid cysts may be functional or nonfunctional, depending on their association with hypercalcemia....
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PMID: 20512295
PDF is available here.
PDF is available here.
Abstract
We discuss three cases, highlighting their contributions....
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PMID: 19566973
PDF is available here.
PDF is available here.
Abstract
Among 6621 patients submitted to neck US investigation, a PC (mean diameter 36.4+/-14.2 mm; range 25-61 mm) was diagnosed in 5 cases. Serum PTH levels were high in all the patients (221+/-140.7 pg/ml; range 111-456 pg/ml), whereas serum calcium levels only in 3 subjects (10.8+/-1.4 mg/dl; range 9.2-...
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PMID: 19636206
PDF is available here.
PDF is available here.
Journal of Internal Medicine (234)4 2009
Abstract
Abstract
Thyroid and parathyroid diseases are fairly common and can be either hereditary or sporadic in nature. Tumors and tumor-like processes account for the majority of surgical pathology specimens in both of these endocrine organs. Molecular alterations are well known to occur in both the hereditary and...
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PMID: 19098464
PDF is available here.
PDF is available here.
Abstract
We reported the clinical manifestation and pathological findings in patients with hypercalcemia and metastatic calcification. In addition, we addressed the possible mechanism and the preventive strategy for the acute episode of ALI due to hypercalcemic crisis. We encountered five patients with long-...
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PMID: 19280887
PDF is available here.
PDF is available here.
Abstract
To our knowledge this is a first population-based study on nonthyroid endocrine diseases. The results call for further studies to sort out the challengingly high sibling risk for many individual nonthyroid endocrine diseases, whether they are due to bias or possible recessive effects....
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PMID: 18827002
PDF is available here.
PDF is available here.
Abstract
Abstract
The history of thyroid and parathyroid surgery dates back thousands of years, but the developments leading to the contemporary era began just over a century ago. Pioneers in the field include Billroth, Kocher, Mayo, and Halsted. This article examines the historical progress of operating on the thyro...
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PMID: 19040968
PDF is available here.
PDF is available here.
Abstract
This article highlights the major milestones in the development of radioguided reoperative techniques and reviews the recent literature concerning reoperative thyroid and parathyroid surgery.
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PMID: 19040978
PDF is available here.
PDF is available here.
Abstract
We included 607 patients, representing 20% of the pediatric endocrine operations done between 1999 and 2005 in the United States. Seventy-six percent of patients were female. Among the procedures performed, 92% were thyroidectomies and 8% were parathyroidectomies. Surgeons were classified as follows...
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PMID: 19040991
PDF is available here.
PDF is available here.
Abstract
Hospital data were available for 335 reoperations (85%). There were 134 avoidable (34%) and 201 unavoidable (66%) procedures. Primary hyperparathyroidism (HPT) and thyroid cancer each accounted for a third of cases. Of PR from LVC, 77% were avoidable compared with 22% from HVC (P < .001). Of TR from...
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PMID: 19040995
PDF is available here.
PDF is available here.
Abstract
We report the first case of a 35-year-old woman with a metachronous TDC and PTC. The embryologic origins of TDCs and inferior PTCs are revealed from the experience of this case....
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PMID: 19073381
PDF is available here.
PDF is available here.
European Radiology (18)9 2008
Abstract
We present a case of parathyroid cyst and recurrent laryngeal nerve paralysis with illustrations of the clinical, radiological and pathological appearances as well as discussion on the management of this condition....
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PMID: 18679738
PDF is available here.
PDF is available here.
Mayo Clinic Proceedings (83)9 2008
Abstract
We review how mycoses and conventional systemic antifungal treatment can affect the endocrine system and cause metabolic abnormalities. If clinicians are equipped with better knowledge of the endocrine and metabolic complications of fungal infections and antifungal therapy, they can more readily rec...
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PMID: 18775205
PDF is available here.
PDF is available here.
Panminerva Medica (50)3 2008
Abstract
USG. In the thyroid diseases group, USG was particularly useful: 1) to detect additional nodules in glands with suppressed thyroid tissue; 2) to disclose small thyroid nodules (<1 cm) in which it was possible to perform a USG-FNAC. In the parathyroid diseases group, USG was particularly useful for t...
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PMID: 18927523
PDF is available here.
PDF is available here.
Abstract
We present six cases with cystic degeneration of a parathyroid gland causing primary hyperparathyroidism in five patients. CASE REPORTS: A woman at the age of 67 presented with hypercalcaemic crisis due to persistent primary hyperparathyroidism after an operation four years ago. As cervical explorat...
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PMID: 18523916
PDF is available here.
PDF is available here.
Abstract
Hyperparathyroidism represents by a varied spectrum of presentations, from those individuals who have overt symptoms directly attributable to hypercalcemia to those who are asymptomatic at diagnosis. Indications for surgical intervention in the asymptomatic population have changed as the long-term e...
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PMID: 18656035
PDF is available here.
PDF is available here.
Abstract
The most common indication for parathyroid imaging is hyperparathyroidism, which is caused by a solitary parathyroid adenoma in most patients. The primary function of parathyroid imaging is localization of the abnormal parathyroid gland, enabling the surgeon to pursue a minimally invasive resection....
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PMID: 18656034
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
Disease of the parathyroid glands presents most often with hypercalcaemia secondary to excess parathormone (PTH) production. This is due to a solitary functioning parathyroid adenoma. The role of imaging is primarily to localise the functioning adenoma. Disease of the thyroid may present with a neck...
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PMID: 18502599
PDF is available here.
PDF is available here.
World Journal of Surgery (32)6 2008
Abstract
World Journal of Surgery (32)5 2008
Abstract
Viability of cryopreserved parathyroid cells is associated with duration of storage. Parathyroids preserved for greater than 24 months are unlikely to be viable. It seems reasonable to limit parathyroid cryopreservation to 24 months when frozen at -80 degrees C. Further studies are needed to optimiz...
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PMID: 18228092
PDF is available here.
PDF is available here.
Abstract
We define a syndrome featuring both hypophosphatemic rickets and hyperparathyroidism due to parathyroid hyperplasia as well as other skeletal abnormalities. We show that this disease is due to a de novo translocation with a breakpoint adjacent to alpha-Klotho, which encodes a beta-glucuronidase, and...
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PMID: 18308935
PDF is available here.
PDF is available here.
Cirugía Española (83)2 2008
Abstract
Abstract
A 36-year-old Nigerian woman on thrice-weekly dialysis presented with symptoms and signs of hypercalcaemia. Laboratory findings were consistent with tertiary hyperparathyroidism. Parathyroid hormone levels remained elevated and she underwent elective parathyroidectomy. Intra-operatively all 4 parath...
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PMID: 18587734
PDF is available here.
PDF is available here.
Clinical Imaging (32)4 2008
Abstract
The authors describe the computed tomography (CT) and magnetic resonance (MR) imaging findings of a 69-year-old woman and a 69-year-old man with a nonfunctional mediastinal parathyroid cyst. In the described cases, unenhanced CT showed homogeneous areas of water density, and unenhanced MRI showed ho...
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PMID: 18603187
PDF is available here.
PDF is available here.
Abstract
Abstract
Calcium is an important mineral in homeostasis in all vertebrate animals. It is the most abundant mineral in the body, and is the major component of bones and teeth. In addition, calcium is involved in various vital physiologic processes, including blood coagulation, muscle contraction, membrane per...
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PMID: 18165142
PDF is available here.
PDF is available here.
Abstract
The field of reptilian clinical endocrinology is still in its infancy. The thyroid and parathyroid glands are intimately involved with many basic metabolic functions. These glands have been the subject of extensive research studies in reptilian species; however, the effects of abnormal gland functio...
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PMID: 18165144
PDF is available here.
PDF is available here.
Abstract
In recent years the advances in preoperative localization studies, the availability of intraoperative parathyroid hormone (PTH) assay and the introduction of cervicoscopy revolutionized the surgical treatment of primary hyperparathyroidism (PHPT). Several endoscopic and video-assisted techniques for...
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PMID: 18971596
PDF is available here.
PDF is available here.
Abstract
Technological developments have significantly contributed to the rapid evolution of the surgical management of parathyroid disorders. The ability to physiologically determine the intraoperative status of the patient is now possible through the assessment of changing levels of intact parathyroid horm...
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PMID: 18971597
PDF is available here.
PDF is available here.
Il Giornale di chirurgia (29)1-2 2008
Abstract
The diagnostic, therapeutic and healthcare management protocols in parathyroid surgery approved by the 1st Consensus Conference are officially those proposed by the Italian Association of Endocrine Surgery Units (UEC Club) and are subject to review by October, 2009....
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PMID: 18252143
PDF is available here.
PDF is available here.
ANZ Journal of Surgery (77)12 2007
Abstract
Felix Mandl from Vienna has long been acclaimed as having carried out the first parathyroidectomy for primary hyperparathyroidism in 1925. He was not, however, the first surgeon to have seen the parathyroid glands, either at surgery or in the pathology laboratory. There is evidence that the first in...
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PMID: 17973666
PDF is available here.
PDF is available here.
Clinical calcium (17)12 2007
Abstract
Medical Physics (34)12 2007
Abstract
This investigation tested the hypothesis that visual analysis of iteratively reconstructed tomograms by ordered subset expectation maximization (OSEM) provides the highest accuracy for localizing parathyroid lesions using 99mTc-sestamibi SPECT data. From an Institutional Review Board approved retros...
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PMID: 18196807
PDF is available here.
PDF is available here.
Abstract
Ultrasonography correctly localized the parathyroid adenoma(s) in 148 (69.4%) of the 229 patients with these lesions. Sestamibi scans correctly localized the parathyroid adenoma(s) in 133 (58.1%) of the 229 patients. The agreement between the 2 imaging procedures was moderate (kappa = 0.23; 95% conf...
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PMID: 18086966
PDF is available here.
PDF is available here.
Abstract
Through adherence to these novel criteria, reexploration of the neck could have been prevented in 29% of patients with primary hyperparathyroidism due to multiple gland disease. These novel criteria demand future evaluation to establish their value....
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PMID: 18081439
PDF is available here.
PDF is available here.
World Journal of Surgery (31)11 2007
Abstract
The Surgeon (5)5 2007
Abstract
We discuss the underlying pathology and investigative procedures, as well as the various techniques used, all of which now have excellent outcomes at a minimal cost and with minimal complications. Based on our own experience we recommend the use of a lateral focused mini-incision for both MIP and MI...
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PMID: 17958230
PDF is available here.
PDF is available here.
Abstract
Abstract
Parathyroid cysts are much less common than other cystic lesions of the neck. The great majority of parathyroid cysts are endocrine non-functioning. Parathyroid cysts may become symptomatic because of hormonal activity or due to the size and pressure effects. This is a case history of a 43 year-old...
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PMID: 17853554
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
FNA failed to recognize the parathyroid origin of the lesions in all but 2 cases with known hyperparathyroidism. Most aspirates were misinterpreted either as suspicious for or as thyroid neoplasms because of high cellularity and absence of colloid. Histologically, the lesions proved to be parathyroi...
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PMID: 17334991
PDF is available here.
PDF is available here.
ANZ Journal of Surgery (77)4 2007
Abstract
We report a case where a functioning parathyroid cyst presented as a retrosternal goitre to emphasize the potential pitfalls associated with their diagnosis and management....
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PMID: 17388841
PDF is available here.
PDF is available here.
Zentralblatt für Chirurgie (132)2 2007
[Hormone inactive parathyroid cyst: rare differential diagnosis in the evaluation of cervical cysts]
Abstract
We report the case of a 57-year-old patient presenting to our department with a hormone inactive parathyroid cyst. Final diagnosis was achieved eventually after histological examination of the resected specimen, which is the reason for evaluating the current data for preoperative management of this...
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PMID: 17516326
PDF is available here.
PDF is available here.
Abstract
Considerable progress has been made in the development and testing of agents to treat osteoporosis. Most impressive are reports on new antiresorptive agents--both bisphosphonates (ibandronate and zoledronic acid) and monoclonal antibodies (MAbs) (denosumab) directed against receptor activator of nuc...
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PMID: 17341572
PDF is available here.
PDF is available here.
Abstract
MIBI is preferred over USG in pHPT patients planning for MIP. Weight of adenoma appeared to be the only clinicopathologic factor determining localization accuracy....
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PMID: 17236840
PDF is available here.
PDF is available here.
Abstract
Parathyroid (PT) hyperplasia is a major feature of secondary hyperparathyroidism (SH) in uremia. The transforming growth factor-alpha (TGFalpha) / epidermal growth factor receptor (EGFR)Ethgrowth loop is the main contributor to uremia-induced PT hyperplasia. Since integrin beta1 and focal adhesion k...
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PMID: 17514628
PDF is available here.
PDF is available here.
World Journal of Surgery (31)1 2007
Abstract
Most parathyroid cysts are nonfunctional and are rarely symptomatic. They are usually located in an inferior gland. If aspirated, most of the cysts reaccumulate fluid. Operative management is usually straightforward and alleviates symptoms and any biochemical abnormalities caused by the cyst....
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PMID: 17180630
PDF is available here.
PDF is available here.
Clinical Endocrinology (65)6 2006
Abstract
Based on the absence of identifiable DNA sequence alterations in these forms of parathyroid dysfunction, it is unlikely that mutation of the PTH 3'-UTR contributes frequently to their pathogenesis....
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PMID: 17121534
PDF is available here.
PDF is available here.
Cirugía Española (80)6 2006
Abstract
1. The sensitivity of MIBI reached 89.46%. In the absence of thyroid nodules, MIBI diagnosed 100% of single lesions. Pathological thyroid processes produced false-positive results (5.2%) and there were diagnostic errors (4%). 2. MIBI scintigraphy was more sensitive than US and CAT. 3. Positive, sing...
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PMID: 17192222
PDF is available here.
PDF is available here.