Abstract
This LESS seems to be a simple and practical tool to quantify late effects in former brain tumor patients. Although both groups differ significantly with regard to neurocognitive parameters and severity of late effects, this does not apply for all QoL outcomes. Neurological late effects seem to be m...
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PMID: 18974990
PDF is available here.
Abstract
We investigated the hypothesis that DHEA metabolism may be increased in a reactive prostate stroma environment in the presence of proinflammatory cytokines such as transforming growth factor beta1 (TGFbeta1), and further, whether red clover extract, which contains a variety of compounds including is...
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PMID: 19141600
PDF is available here.
Abstract
There is no doubt that the nervous system is involved in the etiopathogenesis of various pathological states and diseases. Interactions between the nervous, endocrine, and immune systems might represent the anatomical and functional basis for understanding the pathways and mechanisms that enable the...
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PMID: 19114982
PDF is available here.
Abstract
Endocrine therapy, the first targeted therapy in oncology, is the most successful systemic therapy in the management of estrogen receptor (ER)-positive breast cancer. Approximately 50% of patients with advanced disease do not respond to first-line treatment with tamoxifen, and many women who receive...
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PMID: 20130429
PDF is available here.
L Orlando,
P Fedele,
M Cinefra,
F Sponziello,
N Calvani,
M C Chetrì,
P Rizzo,
M D'Amico,
P Schiavone,
M Portaluri,
M Criscuolo,
S Burlizzi and
S Cinieri
Abstract
These results are largely irrespective of age, use of chemotherapy or other tumor features. Moreover, the expert panel of the St. Gallen Conference accepted both tamoxifen or tamoxifen plus ovarian suppression as standard endocrine therapy for premenopausal breast cancer patients with endocrine-resp...
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PMID: 20130426
PDF is available here.
Abstract
We have analyzed with microarrays five tissues from the endocrine axis (hypothalamus, adenohypophysis, thyroid gland, gonads and fat tissue) of 16 pigs from both sexes pertaining to four extreme breeds (Duroc, Large White, Iberian and a cross with SinoEuropean hybrid line). Using a Bayesian linear m...
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PMID: 19239697
PDF is available here.
Abstract
Phenolic compounds may be of natural or anthropogenic origin and be present in the environment as well as in food. They comprise a large and diverse group of compounds that may be either beneficial or harmful for consumers. In this review first a non-exhausting overview of interesting phenolics is g...
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PMID: 19158655
PDF is available here.
Abstract
This article is the second in a three-part series discussing the effects of long periods of bedrest on the body. It explores what happens to the gastrointestinal, endocrine and renal systems when a person is confined to bed. The effects on the reproductive and nervous systems are also covered. Part...
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PMID: 19579399
PDF is available here.
Abstract
Endocrine fibroblast growth factors (FGFs) function as hormones that maintain specific metabolic states by controlling homeostasis of bile acid, glucose, fatty acid, phosphate, and vitamin D. Endocrine FGFs exert their biological activity through a common design of coreceptor system consisting of th...
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PMID: 19319846
PDF is available here.
Abstract
After statistical analysis of the data a significant decrease of cortisol levels of patients was found, which was not directly correlated with radon concentration. In the case of thyroid hormones, there were no significantly detectable changes of the hormone levels except for low radon concentration...
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PMID: 19296342
PDF is available here.
Abstract
Hystochemical and immunohystochemical investigations revealed APUD tumor cells in malignant endometrial and breast tumors, which affect elderly women. Identification of the hormones produced by APUD-cells in carcinomas and neuroendocrine tumors could form the basis for selecting the optimal method o...
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PMID: 19827687
PDF is available here.
Abstract
We investigated the relative influence of early auditory experience, acoustic features of songs, and estrogen availability on song responsiveness in female zebra finches. Juvenile female zebra finches were tutored for 10 days with 40 songs per day with one of three acoustically different song types-...
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PMID: 18804474
PDF is available here.
Abstract
In the mammosomatotrophic cell line GH3, both GH and PRL secretion were decreased, reflecting the diminished PRL concentrations in the pituitary glands of infected mice. Additionally, expression of extracellular matrix proteins, e.g. laminin, was increased in T. cruzi-infected GH3 cells, which may b...
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PMID: 19246944
PDF is available here.
Abstract
We start by describing environmental chemicals that can bind to xenosensors and nuclear hormone receptors. We then describe the receptors most commonly targeted by environmental chemicals. Finally, the mechanisms by which receptor-mediated events can disrupt the system are depicted....
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PMID: 19157066
PDF is available here.
William J Kraemer,
Barry A Spiering,
Jeff S Volek,
Gerard J Martin,
Robert L Howard,
Nicholas A Ratamess,
Disa L Hatfield,
Jakob L Vingren,
Jen Yu Ho,
Maren S Fragala,
Gwendolyn A Thomas,
Duncan N French,
Jeffrey M Anderson,
Keijo Häkkinen and
Carl M Maresh
Abstract
I football players gave consent to participate in the investigation in the ninth game of the season. Sixteen players started the game and played the entire game (PL), and 12 others did not play and were on the bench during the game (DNP). Each player had fasted blood samples obtained at the same tim...
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PMID: 19077734
PDF is available here.
Abstract
Nerve growth factor (NGF) is a signaling molecule, originally discovered for its role on differentiation and survival of peripheral sensory and sympathetic neurons. It has also been associated with functional activities of cells of the immune and endocrine systems. NGF biological activity is mediate...
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PMID: 19774790
PDF is available here.
Abstract
Embryonic stem (ES) cells which constitutively express the Pdx-1, Ngn-3, NeuroD1, Nkx2.2, and Nkx6.1 transcription factors were engineered by means of lentiviral vectors, following a multi-step infection procedure to successively generate ES cell lines expressing one, two, and three factors, respect...
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PMID: 19378248
PDF is available here.
Abstract
Changes in the maternal diet either throughout pregnancy, or at defined stages therein, can have pronounced effects on organogenesis in conjunction with endocrine sensitivity. These processes can be brought about by either maternal consumption of an imbalanced diet and/or a global reduction in macro...
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PMID: 19536669
PDF is available here.
Abstract
Caloric restriction seems to be the best positive modulator of metabolism to achieve longevity. Other specific metabolic adaptations, even those genetically induced, might also play a role in the health of centenarians.
Copyright 2009 S. Karger AG, Basel....
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PMID: 19153500
PDF is available here.
Abstract
We summarize the recent advances in the proteomics of adipose tissue, and discuss the identified proteins that potentially play important roles in insulin resistance and diabetes....
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PMID: 19086862
PDF is available here.
Abstract
Over the years, the development of assisted reproductive technology to bypass male factor infertility has improved drastically. Considered one of the most perplexing disorders in the reproductive field, male factor infertility is prevalent and may be on the rise. Unfortunately, its aetiology remains...
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PMID: 19079972
PDF is available here.
Abstract
Our study using a rat model demonstrated that exposure to light at night suppressed the expected nocturnal rise in melatonin, increased plasma corticosterone, and disrupted core clock gene expression in the hypothalamus and the adrenal gland. These effects were prevented by filtration of a 10-nm ban...
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PMID: 18687787
PDF is available here.