Find your PDFs fast.
Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Bioreactors (0):
Recent article
Bioreactors
Biomaterials (32)34 2011
Abstract
We have developed a bioreactor containing single hollow fiber membranes that requires relatively small amounts of cells. Special hollow fiber membranes with the skin layer on the outer surface and consisting of polyethersulfone/polyvinylpyrrolidone were developed. The results suggested that such hol...
|
PMID: 21872923
PDF is available here.
PDF is available here.
| < More recent | Older article > |
Biomaterials (32)34 2011
Abstract
We have developed a bioreactor containing single hollow fiber membranes that requires relatively small amounts of cells. Special hollow fiber membranes with the skin layer on the outer surface and consisting of polyethersulfone/polyvinylpyrrolidone were developed. The results suggested that such hol...
|
PMID: 21872923
PDF is available here.
PDF is available here.
Biomaterials (32)34 2011
Abstract
We have developed a bioreactor containing single hollow fiber membranes that requires relatively small amounts of cells. Special hollow fiber membranes with the skin layer on the outer surface and consisting of polyethersulfone/polyvinylpyrrolidone were developed. The results suggested that such hol...
|
PMID: 21872923
PDF is available here.
PDF is available here.
Abstract
Proteomic analysis requires the combination of an extensive suite of technologies including protein processing and separation, micro-flow HPLC, MS and bioinformatics. Although proteomic technologies are still in flux, approaches that bypass gel electrophoresis (gel-free approaches) are dominating the...
|
PMID: 21824287
PDF is available here.
PDF is available here.
Abstract
The aim of the study was to construct small-diameter vascular grafts using canine mesenchymal stem cells (cMSCs) and a pulsatile flow bioreactor. cMSCs were isolated from canine bone marrow and expanded ex vivo. cMSCs were then seeded onto the luminal surface of decellularized arteri...
|
PMID: 21784877
PDF is available here.
PDF is available here.
Abstract
We consider here polymeric scaffold-based perfusion bioreactors, where an interstitial fluid supplies nutrients and oxygen to the growing biomass. At the same time, the fluid-induced shear acts as a physiologically relevant stimulus for the metabolic activity of cells, provided that the shear stress...
|
PMID: 20865436
PDF is available here.
PDF is available here.
Abstract
Innovative wastewater treatment technologies are developed to respond to changing regulatory requirements, increase efficiency, and enhance sustainability or to reduce capital or operating costs. Drawing from experience of five successful new process introductions from both the inventor/developer's a...
|
PMID: 21751707
PDF is available here.
PDF is available here.
Abstract
The moving bed biofilm reactor (MBBR) can operate as a 2- (anoxic) or 3-(aerobic) phase system with buoyant free-moving plastic biofilm carriers. These systems can be used for municipal and industrial wastewater treatment, aquaculture, potable water denitrification, and, in roughing, secondary, terti...
|
PMID: 21751715
PDF is available here.
PDF is available here.
Abstract
Anaerobic transformations of wastewater organic matter in the bulk water phase of collection system networks were investigated in laboratory-scale experiments. The wastewater was collected from three locations, which provided samples with different characteristics, ranging from young to mature. Hydro...
|
PMID: 21751712
PDF is available here.
PDF is available here.
Abstract
Thickened waste activated sludge (TWAS) was pretreated with microwave irradiation to temperatures higher than the boiling point (between 110 and 175 degrees C) using different microwave intensities. Biochemical methane potential (BMP) assays demonstrated that, although mesophilic anaerobic digestion...
|
PMID: 21751714
PDF is available here.
PDF is available here.
Abstract
Inhomogeneous and uncontrolled cellular and tissue responses in bone tissue engineering constructs, as a result of heterogeneous oxygen delivery throughout the scaffold volume, is one of the hurdles hampering clinical transfer of cell-scaffold combinations. This study presents an acc...
|
PMID: 21332298
PDF is available here.
PDF is available here.
Abstract
These results indicate that the combined mechanical stimulation can enhance the differentiation of pre-osteoblasts more efficiently than simple stimuli, in spite of no effect on cell proliferation....
|
PMID: 21532314
PDF is available here.
PDF is available here.
Abstract
Algae are an attractive biofuel feedstock because of their fast growth rates and improved land use efficiency when compared with terrestrial crops. Process train components needed to produce algal biofuels include (1) cultivation, (2) harvesting, and (3) conversion into usable fuel....
|
PMID: 21553588
PDF is available here.
PDF is available here.
Abstract
We present a new heart valve bioreactor, having as its centrepiece a ventricular assist device (VAD), which exposes the cell-scaffold constructs to a wider array of mechanical forces. The pump of the VAD has two chambers: a blood and a pneumatic chamber, separated by an elastic membrane. Pulsatile a...
|
PMID: 20687125
PDF is available here.
PDF is available here.
Abstract
The goal of this study was to enhance pullulan production by evaluating the effects of different fermentation parameters. Various carbon sources and their concentrations, yeast extract (YE) concentrations, fermentation temperatures and various pH profiles were examined. The optimal growth condition f...
|
PMID: 21421674
PDF is available here.
PDF is available here.
Abstract
To avoid the inhibition of methane production by ammonia that occurs during the degradation of garbage, anaerobic digestion with prior ammonia production and subsequent stripping was investigated. In the ammonia production phase, the maximum ammonia concentration was approximately 28...
|
PMID: 21094085
PDF is available here.
PDF is available here.
Abstract
Matrix metalloproteinase 8 (MMP-8) has been reported to have a key role in several pathologic conditions, like heart diseases, osteoarthritis, multiple sclerosis, and various other inflammatory conditions. Therefore, there is a great interest regarding the development of MMP-8 select...
|
PMID: 21397574
PDF is available here.
PDF is available here.
Abstract
We biofabricated a thick dermal-like tissue by sequentially combining two steps: a μTPs production and assembly followed by tissue maturation in a purpose-built bioreactor. The μTPs were produced by first seeding bovine primary fibroblasts on gelatine microparticles and then cultivating them in st...
|
PMID: 20704470
PDF is available here.
PDF is available here.
Abstract
Highly pathogenic influenza viruses pose a constant threat which could lead to a global pandemic. Vaccination remains the principal measure to reduce morbidity and mortality from such pandemics. The availability and surging demand for pandemic vaccines needs to be addressed in the preparedness plans....
|
PMID: 21283675
PDF is available here.
PDF is available here.
Abstract
Cell seeding and attachment in three-dimensional scaffolds is a key step in tissue engineering with implications for cell differentiation and tissue development. In this work, two new seeding methods were investigated using human chondrocytes and polyglycolic acid (PGA) fibrous mesh...
|
PMID: 21312366
PDF is available here.
PDF is available here.
Abstract
The bioprocess development cycle is a complex task that requires a complete understanding of the engineering of the process (e.g., mass transfer, mixing, CO(2) removal, process monitoring, and control) and its affect on cell biology and product quality. Despite their widespread use i...
|
PMID: 21523928
PDF is available here.
PDF is available here.
Abstract
We treated lungs from adult rats using a procedure that removes cellular components to produce an acellular lung extracellular matrix scaffold. This scaffold retains the hierarchical branching structures of airways and vasculature, as well as a largely intact basement membrane, which comprises colla...
|
PMID: 21445030
PDF is available here.
PDF is available here.
Abstract
Study in CBA line mice of immunogenicity of cold adapted reassortant influenza virus H5N2 vaccine strain samples produced in rollers in MDCK and Vero cell cultures by using plant derived components.
Antibody levels in blood sera and nasal swabs, lungs and small intest...
|
PMID: 21812141
PDF is available here.
PDF is available here.
Abstract
We describe the use of computer-controllable suspension bioreactors to form EBs in an automated and highly reproducible process and their subsequent differentiation along the osteoblast lineage. The development of the differentiating cells taken from bioreactor EBs to EBs formed in static control cu...
|
PMID: 21042990
PDF is available here.
PDF is available here.
Abstract
Cell culture in two dimensions has been routinely and diligently undertaken in thousands of laboratories worldwide for the past four decades. However, the culture of cells in two dimensions is arguably primitive and does not reproduce the anatomy or physiology of a tissue for informative or useful s...
|
PMID: 21042962
PDF is available here.
PDF is available here.
Abstract
A large-scale stirred culture system for the expansion of mouse embryonic stem cells (mESCs) in spinner flasks under serum-free conditions was established using macroporous microcarriers for cell attachment and growth. This type of microcarrier was chosen as it potentially offers more protection to...
|
PMID: 21042989
PDF is available here.
PDF is available here.
Abstract
We outline in this chapter the development of an NGC that incorporates aligned poly-L-lactide fibres for supporting the growth of organised Schwann cells within a three-dimensional scaffold in vitro. A closed loop bioreactor for growing cells within NGC scaffolds is described together with a method...
|
PMID: 21042971
PDF is available here.
PDF is available here.
Abstract
There are several types of bioreactors currently available for the culture of orthopaedic tissue engineered constructs. These vary from the simple to the complex in design and culture. Preparation of samples for bioreactors varies depending on the system being used. This chapter presents data and de...
|
PMID: 21042966
PDF is available here.
PDF is available here.
Abstract
We propose a novel approach to heart valve tissue engineering based on bioreactor conditioning of mesenchymal stem cell-seeded, valve-shaped constructs assembled from layered collagenous scaffolds. Fibrous scaffolds were prepared by decellularization of porcine pericardium and spongiosa scaffolds by...
|
PMID: 20673028
PDF is available here.
PDF is available here.
Abstract
Tissue engineered cartilage can be grown in vitro with the use of cell-scaffold constructs and bioreactors. The present study was designed to investigate the effects of perfusion bioreactors on the chondrogenic potential of engineered constructs prepared from porous silk fibroin scaf...
|
PMID: 20949478
PDF is available here.
PDF is available here.
Abstract
Charge neutralisation is an important mechanism in (polyelectrolyte) conditioning of biotic sludges and required for efficient sludge dewatering. Based on results from streaming potential and zeta potential measurements, it has been suggested that charge neutralisation is more complete on the outside...
|
PMID: 21436571
PDF is available here.
PDF is available here.
Abstract
This study investigated the potential of laboratory- scale columns of immobilized micro-algae to disinfect effluents using thermo-tolerant coliforms (TTC) as a model system. Cells of a Chlorella species isolated from a waste stabilization pond complex in Northeast Brazil were immobilized in calcium a...
|
PMID: 21436540
PDF is available here.
PDF is available here.
Abstract
This study evaluates the performance of four 2.3 m deep pilot-scale, independently loaded, primary facultative ponds treating predominantly domestic sewage in northeast Brazil. The ponds contained longitudinal baffles giving different length to width ratios from 3.55 to 32.4. The ponds had mean hydra...
|
PMID: 21436554
PDF is available here.
PDF is available here.
Abstract
This study aimed at the investigation of genotoxic effects of swine effluents from different stages of a treatment system for swine wastes through bioassay of stamen hairs and micronuclei in Tradescantia (clone BNL 4430). No significant differences (p≥0.05) regarding the genic muta...
|
PMID: 21411948
PDF is available here.
PDF is available here.
Abstract
Algae are produced in considerable quantities in oxidation ponds, and may negatively affect receiving waters when discharged at high concentration. Thus in some instances they require removal prior to effluent discharge, which may be enhanced using flocculants such as alum. Harvested...
|
PMID: 21411930
PDF is available here.
PDF is available here.
Abstract
To improve the efficiency of low-strength domestic wastewater treatment, an immobilised-microorganism biological aerated filter (I-BAF) was established for simultaneous carbon, nitrogen and phosphorus removal. The I-BAF performance was systematically evaluated under continuous and in...
|
PMID: 21411937
PDF is available here.
PDF is available here.
Abstract
9alpha-Hydroxy derivatives were prepared from 11 steroids ofandrostane and pregnane series using Rhodococcus erythropolis VKPM Ac-1740 culture with 0.5-20 g/l substrate concentration in the reaction mixture. 9alpha-Monohydroxylation proceeded regardless of the substituent structure at C17. However, t...
|
PMID: 21950117
PDF is available here.
PDF is available here.
Abstract
Peculiarities of synthesis of surface-active substances (SAS) are studied at periodical cultivation of Rhodococcus erythropolis EK-1 in the AK-210 fermenter on medium containing n-hexadecane. Maximum indicators of SAS synthesis (concentration of extra cellular SAS is 7.2 g/l; factor of emulsification...
|
PMID: 21950118
PDF is available here.
PDF is available here.
Abstract
To estimate the expectable enhanced biological phosphorus removal value of a wastewater, the concentration of volatile fatty acids (VFAs) and the biochemical acidogenic potential (BAP) are generally determined on grab samples of wastewater, as these variables are prone to rapid change after sampling....
|
PMID: 21508542
PDF is available here.
PDF is available here.
Abstract
Abstract
A promising approach to bone tissue engineering lies in the use of perfusion bioreactors where cells are seeded and cultured on scaffolds under conditions of enhanced nutrient supply and removal of metabolic products. Fluid flow alterations can stimulate cell activity, making the eng...
|
PMID: 20872752
PDF is available here.
PDF is available here.
Lab On a Chip (10)23 2010
Abstract
We developed a microfluidic device designed to generate stable concentration gradients at low hydrodynamic shear and allowing long term culture of adhering cells. The gradient forms in a culture space between two parallel laminar flow streams of culture medium at two different concentrations of a gi...
|
PMID: 20936235
PDF is available here.
PDF is available here.
Bioresource Technology (101)23 2010
Abstract
A novel enzyme membrane reactor with sandwich structure has been developed by confining glucosidase between two sheets of ultrafiltration membranes to effectively convert maltose to isomaltooligosaccharides (IMOs). The hydrophilic ultrafiltration membranes, which were prepared by phase inversion met...
|
PMID: 20655202
PDF is available here.
PDF is available here.
Water Environment Research (82)11 2010
Abstract
The efficacy of UV disinfection of water depends on the ability of radiation to pass from UV lamps through the quartz sleeves that encase them; the accumulation of metal-containing foulants on sleeve surfaces inhibits disinfection by absorbing radiation that would otherwise be available for inactiva...
|
PMID: 21141389
PDF is available here.
PDF is available here.
Abstract
Our analysis showed 882 genes that were downregulated and 505 genes that were upregulated after exposure to simulated microgravity. Gene ontology clustering revealed a wide variety of affected genes with respect to cell compartment, biological process, and signaling pathway clusters. The data sets s...
|
PMID: 20807102
PDF is available here.
PDF is available here.
Abstract
The aim of this study was to compare the effect of industrial discharges on the anaerobic treatment of domestic wastewater in both laboratory and pilot-plant scales at mesophilic conditions. The laboratory experiment results have shown the low process efficiency of anaerobic treatment of DW by the u...
|
PMID: 21121456
PDF is available here.
PDF is available here.
Abstract
The effective removal of nitrogen compounds from wastewater has become a critical issue for treatment plants as the awareness of their negative impact on the environment increased. Autotrophic nitrogen removal has become an interesting alternative to the more conventional heterotrophic processes, as...
|
PMID: 21121462
PDF is available here.
PDF is available here.
Abstract
The autotrophic nitrogen removal process (partial nitritation combined with the Anammox process) is a new and sustainable nitrogen removal technique for nitrogen-rich streams. A modelling study has been performed to define optimal process conditions (temperature, oxygen supply, pH and biomass retent...
|
PMID: 21121455
PDF is available here.
PDF is available here.
Abstract
Four simulated landfill bioreactors operating under different experimental conditions were evaluated in this study. The reactors were filled with the organic fraction of municipal solid wastes (MSW) and operated as: anaerobic, anaerobic with pH adjustment, semi-aerobic and intermittent aeration bior...
|
PMID: 21121461
PDF is available here.
PDF is available here.
Waste Management (30)11 2010
Abstract
In this study, an anaerobic sequencing batch reactor (ASBR) was operated with leachate from Brady Road Municipal Landfill in Winnipeg, Manitoba, Canada. Leachate was collected twice from the same cell at the landfill, during the first and 70th day of the study, and then fed into the ASBR. The ASBR w...
|
PMID: 20483580
PDF is available here.
PDF is available here.
Waste Management (30)11 2010
Abstract
A series of processes by biofilter and Fenton oxidation to treat mature landfill leachate has been devised. At a hydraulic loading rate of 20 l m(-3)d(-1), a biofilter packed with aged refuse is found to remove 80% of chemical oxygen demand (COD), 89% of ammonia nitrogen and 96% of total phosphorus...
|
PMID: 20663656
PDF is available here.
PDF is available here.
Waste Management (30)11 2010
Abstract
Sustainable disposal of municipal solid waste (MSW) requires assurance that contaminant release will be minimized or prevented within a reasonable time frame before the landfill is abandoned so that the risk of contamination release is not passed to future generations. This could be accomplished thr...
|
PMID: 20673711
PDF is available here.
PDF is available here.
Abstract
Streptomyces sp. 7b showed highest xylanase activity among 41 bacterial isolates screened under submerged fermentation. The organism grew over broad pH (5-11) and temperatures range (25-55 degrees C) and displayed maximum xylanase production on wheat bran (1230 U/g) under solid-state fermentation. X...
|
PMID: 20419509
PDF is available here.
PDF is available here.
Journal of Surgical Research (163)2 2010
Abstract
Histological analysis demonstrated sulfated glycosaminoglycans and deposition of collagen type II in constructs from both groups. Constructs cultured in the bioreactor system prior in vivo implantation demonstrated higher levels of DNA, glycosaminoglycans, and hydroxyproline. An increase of 22% in t...
|
PMID: 20538292
PDF is available here.
PDF is available here.
Abstract
We investigated the potential of human fetal hepatocytes (hFH) in a four-compartment hollow fiber-based three-dimensional (3D) perfusion culture system. hFH were isolated from 17- to 19-gestational-week livers and cultured in the 3D perfusion bioreactors for 14 days. Metabolism activity, hepatocyte-...
|
PMID: 19883207
PDF is available here.
PDF is available here.
Abstract
We developed a novel 3D in vitro perfusion system that allows direct investigation of the effects of shear stress on the development of microvasculature in vitro. This system utilizes a 3D collagen gel for suspension of vascular cells and mesenchymal stem cells, through which flow is directly perfus...
|
PMID: 20170423
PDF is available here.
PDF is available here.
Abstract
We demonstrate the application of high-density microarrays targeting universal 16S rRNA genes to evaluate microbial community composition in five biological wastewater treatment reactors in China and the United States. Results suggest a surprisingly consistent composition of microbial community stru...
|
PMID: 20812670
PDF is available here.
PDF is available here.
Abstract
In the present study, two conventional (with and without sand filter) and four additional (moving bed biofilm reactor, ozone, moving bed biofilm reactor combined with ozone and a membrane bio reactor) treatment technologies were operated in small-scale at Hammarby Sjöstad sewage treatment plant, St...
|
PMID: 20570351
PDF is available here.
PDF is available here.
New Microbiologica (33)4 2010
Abstract
A method of cultivating Brucella abortus S19 culture in bioreactor was attempted using three different media. Culture conditions in bioreactor were optimized by varying agitation and aeration parameters. Varying the aeration ranging from 0.5 vvm to 0.8 vvm and agitation rate ranging from 250 rpm to...
|
PMID: 21213590
PDF is available here.
PDF is available here.
Abstract
A Gram-stain-positive, neutrophilic, rod-shaped bacterium, strain A1g(T), was isolated from activated sludge of a bioreactor and was subjected to a polyphasic taxonomic characterization. The isolate grew in the presence of 0-17.0 % (w/v) NaCl and at pH 6.0-9.0; optimum growth was observed in the p...
|
PMID: 19946056
PDF is available here.
PDF is available here.