Abstract
Therapeutic keratoplasty has a definitive role in the management of progressive microbial keratitis refractory to medical therapy. The primary aim of the procedure is to eliminate the infectious disease process and establish the integrity of the globe. This procedure offers a microbiological cure ra...
|
PMID: 20531191
PDF is available here.
Abstract
We compared the frequency of positive FHV-1 PCR test results from 48 clinical cases of ocular disease in cats suspected to be due to FHV-1 between 1 research and 2 commercial laboratories in Canada. We also compared PCR results for Chlamydophila felis and Mycoplasma spp. between the 2 commercial lab...
|
PMID: 20808575
PDF is available here.
Abstract
Injections of HealaFlow below the scleral flap and the conjunctiva at the end of the surgery along with intraoperative application of MMC showed promising IOP-lowering effects in trabeculectomy. A prospective randomised study is required to confirm these preliminary results.
Copyright Georg Thieme V...
|
PMID: 20408072
PDF is available here.
Abstract
A total of 422 PLHIV/SIDA were recruited including 281 who were undergoing HAART. The sex-ratio was 2 female/1 male. Mean age was 34 +/- 2294 years. Involvement of the anterior segment was observed in 36.3% of patients and involvement of the posterior segment in 54.1%. The second most common ocular...
|
PMID: 20486347
PDF is available here.
Abstract
The shunt arrangement, which connects the anterior chamber to potentially microbe-populated cavities or to the lower lid fornix and its flora, might be suspected to allow rapid retrograde invasion of infective agents, resulting in endophthalmitis. In this series of KPro patients, however, the incide...
|
PMID: 19373101
PDF is available here.
Abstract
Red eye is the cardinal sign of ocular inflammation. The condition is usually benign and can be managed by primary care physicians. Conjunctivitis is the most common cause of red eye. Other common causes include blepharitis, corneal abrasion, foreign body, subconjunctival hemorrhage, keratitis, irit...
|
PMID: 20082509
PDF is available here.
Abstract
There were 530 cases admitted with acute orbital inflammation over a 9-year period from 1 July 2000 to 30 June 2009. This study identified a significant association between orbital infection incidence and socioeconomic deprivation and ethnicity. Cases in the moderate deprivation group had 1.5 times...
|
PMID: 20720603
PDF is available here.
Abstract
Immune privilege is the condition in which selected immune responses are suppressed or excluded in certain organs, such as the eye. Immune privilege in the eye was described over 130 years ago, but its significance was not appreciated until the early 1950s. Investigations beginning in the 1970s ushe...
|
PMID: 20128645
PDF is available here.
Abstract
We also isolated recombinant viruses from eye and trigeminal ganglia of KOS+HSV-IL-4 infected mice.
In this study we found that ocular infection of BALB/c mice with a mixture of HSV-IL-4 and KOS resulted in increased death and increased eye disease. In contrast, when mice were infected in one eye wi...
|
PMID: 21139679
PDF is available here.
Abstract
A total of 3295 patients with infective keratitis were evaluated, of whom, 1138 (34.5%) patients had fungal growth alone, 1066 (32.4%) had bacterial growth alone, 33 (1%) had Acanthamoeba growth alone, 83 (2.5%) had mixed microbial growth and the remaining 975 (29.6%) had no growth. Corneal injury w...
|
PMID: 20090138
PDF is available here.
Abstract
Levofloxacin 0.5% ophthalmic solution (Cravit, Quixin, Oftaquix) has well established efficacy and tolerability in the treatment of external ocular infections. Levofloxacin 0.5% ophthalmic solution was generally more effective than ofloxacin 0.3% ophthalmic solution in the treatment of external ocul...
|
PMID: 19537841
PDF is available here.
Abstract
To obtain data beneficial for future treatment by observing the circumstances relating to microorganisms isolated in external ocular infections and drug sensitivity, along with changes in drug-resistant bacteria.
|
PMID: 19489449
PDF is available here.
Abstract
Molecular biology has become a valuable component in many areas of medicine, including ophthalmology. Polymerase chain reaction (PCR) is the most widely used tool. It has proven to be a powerful technique in diagnosis and quantification of microorganisms and antibiotic resistance screening. For a gr...
|
PMID: 19169309
PDF is available here.
Abstract
AE is a rare but severe disease with a potentially deleterious outcome in affected eyes. In our series, 78% of all eyes had stable or improved postoperative visual acuity following various treatment regimens, depending on the severity of each case....
|
PMID: 19169320
PDF is available here.
Abstract
Use of 5% povidone-iodine for 3 minutes prior to cataract surgery achieves a significant reduction in organisms such as CoNS from lid and conjunctival flora....
|
PMID: 19551669
PDF is available here.
Abstract
PCR testing is a useful adjunct in the diagnosis of infectious causes of posterior uveitis. Cases with vascular or optic nerve inflammation, extensive retinitis, or immunocompromise are more likely to have positive PCR results and may benefit from PCR testing of aqueous humor....
|
PMID: 18834576
PDF is available here.
Abstract
Contact lens complications accounted for 9.1% of the referrals into Ophthalmic A&E, a total of 323 appointments. Microbial keratitis was the most common diagnosis (22%), and Klebsiella and Pseudomonas the most common pathogen implicated. A case of Fusarium was also recorded. Optometrists/contact len...
|
PMID: 18599340
PDF is available here.
Abstract
Intraocular inflammation, or uveitis, incorporates a diverse group of infectious and immune-mediated disorders. In addition, some conditions masquerade as uveitis. However, classifying uveitis according to anatomic location in adult and pediatric populations, and appreciating the effect of immune st...
|
PMID: 18606087
PDF is available here.
Abstract
We examine the role of TLRs in microbial keratitis and in noninfectious corneal inflammation, most commonly associated with contact lens wear. we present recent findings on TLR signaling pathways in the cornea, including MyD88- and TRIF-dependent responses and discuss the role of resident macrophage...
|
PMID: 18781257
PDF is available here.
Abstract
The incidence of resuturing was 5.4% (51 eyes). The number of cases requiring resuturing was higher in corneal grafts performed for microbial keratitis (12%) than those for keratoconus (10%) and corneal endothelial decompensation (2.5%; p = 0.08). Wound dehiscence was the leading cause for resuturin...
|
PMID: 18480305
PDF is available here.
Abstract
The aim of the study was to determine the ocular safety of a single intravitreal dose of triamcinolone acetonide (IVTA) in dogs. Eleven healthy dogs received a single IVTA injection (8 mg) through the mid-temporal pars-plana of the left eye (OS) using a 27G needle. The dogs were re-evaluated immedia...
|
PMID: 17466546
PDF is available here.
Abstract
We describe effects of infliximab in the treatment of three cases of orbital inflammation and two cases of chronic relapsing inflammatory optic neuropathy, all of which were unresponsive to alternative immune modulators. The patients received relief of symptoms and signs of inflammation in all five...
|
PMID: 18408083
PDF is available here.
Abstract
Although there is no consensus regarding the intravitreal injection procedure technique, the incidence of suspected endophthalmitis was very low in a large series of injected patients in a community setting and the incidence compares favorably with that reported in clinical trials where much more ex...
|
PMID: 18329624
PDF is available here.
Abstract
In this series of patients with chronic non-infectious uveitis, anti-TNF-alpha therapy was effective and safe. Further clinical studies are needed to determine an adequate duration of therapy....
|
PMID: 18454398
PDF is available here.
Abstract
Ocular trauma and infectious keratopathy dominated among the primary diseases of corneal perforation in Shandong Province, China, during the past 10 years. HSK seems to be the most common cause of repeated corneal perforation. Recurrent primary diseases and implant autoproteolysis and infection more...
|
PMID: 18280452
PDF is available here.
Abstract
Injection-related complications such as infectious endophthalmitis, retinal detachment, and traumatic cataract may occur with a frequency of about 0.15+/-0.05% after intravitreal injections of bevacizumab or triamcinolone, independently of the drug injected....
|
PMID: 18292795
PDF is available here.
Abstract
The spectrum of uveitis in northern Thailand included 27% of HIV-infected patients with cytomegalovirus retinitis. Causes of non-HIV uveitis were similar to those often observed in the Far East, but the specific prevalences of these disorders were distinct from that found in India and Japan....
|
PMID: 18369063
PDF is available here.
Abstract
Choroidal neovascularisation (CNV) is a rare but important cause of visual impairment in children. There have been considerable recent advances in our understanding of both the pathogenesis and the management of this sight-threatening complication. New treatment modalities for these neovascular lesi...
|
PMID: 18369058
PDF is available here.
Abstract
We differentiate three kinds of red eye: localised, diffused and perikeratic injection. The last one must be recognized because of its association with severe ocular diseases. Diagnosis must be sure and treatment has to be efficient to not pertubate childrens visual development. Unfortunately, physi...
|
PMID: 18506971
PDF is available here.
Abstract
The ocular surface immunity is a remarkable combination of the innate immune and adaptive immune systems, designed to prevent microbial invasion while minimizing damage to delicate ocular tissue. The innate immune system uses a variety of methods to minimize microorganism invasion, including mechani...
|
PMID: 18299004
PDF is available here.
Abstract
The development of DNA microchip analysis continues to progress. This development provides us with new biological knowledge. DNA microchip analysis can be divided into expression profiling and genotyping. In infectious disease, DNA microchip analysis helps us to identify the pathogen.
|
PMID: 18318272
PDF is available here.
Abstract
Corneal grafts with eye tissue obtained from donors dying in the hospital or with cancer may have an increased risk of postsurgical endophthalmitis, possibly due to donor-to-host microbial transmission. Together with donor screening and processing, improvements in microbiological control may reduce...
|
PMID: 18268215
PDF is available here.
Abstract
This study highlights that sterilisation of tonometer prisms was inconsistent in a local audit. Nationally, practices were varied. The majority of ophthalmology departments continued to use non-disposable tonometer prisms, but few seemed aware of the Royal College of Ophthalmologists' recommendation...
|
PMID: 17703987
PDF is available here.
Abstract
The 38 S. pneumoniae isolates from eye infections belonging to 15 serotypes were placed in to 11 PFGE types and 15 ribotypes. The 9 systemic isolates (7 seotypes) were distributed in 7 PFGE types and 6 ribotypes. The 14 commensal isolates were placed in 11 serotypes, 5 PFGE types and 6 ribotypes. Mo...
|
PMID: 18403796
PDF is available here.
Abstract
Managing the inflamed or infected eye in the emergency setting presents a diagnostic and therapeutic challenge to the emergency physician; the causes and prognoses range from benign, self-limited illness to organ-threatening pathology. A careful history, with attention to comorbid illnesses and time...
|
PMID: 18249257
PDF is available here.
Abstract
Intrauterine infections are important causes of childhood blindness in both developed and developing countries. Chorioretinal scars are the most characteristic eye manifestation of a congenital or prenatal infection. The various ocular manifestations of congenital infections, summarized by the mnemo...
|
PMID: 18348876
PDF is available here.
Abstract
The discovery of DEFB-109 on the ocular surface enhances our knowledge of the profile of AMPs at this important mucosal surface. The fact that its expression is significantly reduced in both inflammatory and infective ocular surface disease reflects not only an intimate balance between this host def...
|
PMID: 18172071
PDF is available here.
Abstract
Infectious keratitis is a fairly common entity in India. However while paying attention to the primary entity, the associated events may be overlooked. Enhanced pain usually suggests a worsening of the condition or development of associated problems like secondary glaucoma. However, contrary to logi...
|
PMID: 18417823
PDF is available here.
Abstract
Standard recommended guidelines for diagnosis of infectious keratitis do exist. Based on an extensive Medline literature search, the various investigative modalities available for aiding the diagnosis of microbial keratitis have been reviewed and described briefly. Preferred practice patterns have b...
|
PMID: 18417821
PDF is available here.
Abstract
This section provides guidelines on medical therapy of patients with infectious keratitis. In addition to initial empirical therapy, preferred medications, once the organisms responsible are isolated, are discussed. Atypical mycobacterial keratitis following lasik is described. General guidelines fo...
|
PMID: 18417822
PDF is available here.
Abstract
We describe the salient clinical features which can help arrive at a diagnosis to begin appropriate treatment immediately, prior to the laboratory report....
|
PMID: 18417820
PDF is available here.
Abstract
Besifloxacin acts as an anti-inflammatory agent in monocytes in vitro; this attribute may enhance its efficacy in ocular infections with an inflammatory component and warrants further investigation....
|
PMID: 17965029
PDF is available here.
Abstract
To review and determine the attributed causes of deaths among patients who died in Sekuru Kaguvi Hospital (SKH) Eye Unit Wards between August 1984 and October 2008
Retrospective study of completed BD12 forms and case records of inpatients who died betweenAugust 1984 a...
|
PMID: 21644419
PDF is available here.