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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Genes, Homeobox (0):
Recent article
Genes, Homeobox
Abstract
Male fetal mortality in group A, B, C, D, and E were 3.57%, 6.90%, 12.00%, 19.23% and 36.36%, respectively, which showed a dose-effect relationship between DES and the male fatal mortality (r=0.999, P<0.01). DTA in group B, C, D and E were (23.7+/-1.7) U, (38.8+/-1.9) U, (49.3+/-1.8) U and (58.6+/-2...
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PMID: 19534997
PDF is available here.
PDF is available here.
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Human Genomics (3)3 2009
Abstract
Human Genomics (3)3 2009
Abstract
We analyse these results and show that the biophysical model explains them successfully....
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PMID: 19403461
PDF is available here.
PDF is available here.
Abstract
We analyzed the dynamic association of MLL and H3K4 trimethylation at different stages of the cell cycle. Interestingly, MLL1, which is normally associated with transcriptionally active chromatins (G1 phase), dissociates from condensed mitotic chromatin and returns at the end of telophase when the n...
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PMID: 19220463
PDF is available here.
PDF is available here.
Cell Cycle (8)5 2009
Abstract
We offer a comprehensive coverage of currently-available in vitro and in vivo models of human epithelial ovarian cancer, focusing on latest updates of genetically-modified rodent and human models and the valuable information conveyed by them....
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PMID: 19221485
PDF is available here.
PDF is available here.
Cell Cycle (8)5 2009
Abstract
We offer a comprehensive coverage of currently-available in vitro and in vivo models of human epithelial ovarian cancer, focusing on latest updates of genetically-modified rodent and human models and the valuable information conveyed by them....
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PMID: 19221485
PDF is available here.
PDF is available here.
Abstract
In cultured prostate cancer cells cAMP blocks proliferation and induces neuroendocrine differentiation. Pyk2 expression inversely correlates with malignancy of prostate cancer. The aim of this study was to investigate the interaction between cAMP and Pyk2 in the prostate. EPN cells, a line derived f...
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PMID: 19106639
PDF is available here.
PDF is available here.
Abstract
We analyzed HOX genes through profiling with multiplex RT-PCR. The results showed that the expression patterns of four HOX genes, HOXA7, HOXB3, HOXA3, and HOXB13, significantly changed during angiogenesis. The expression levels of HOXA7 and HOXB3 were dramatically increased, whereas those of HOXA3 a...
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PMID: 17972163
PDF is available here.
PDF is available here.
Abstract
We will focus on the role of short ncRNAs that repress Hox genes in Drosophila and mammals by RNA interference (RNAi), on long ncRNAs that may repress a Hox in cis in Drosophila by transcriptional interference, and on a novel long ncRNA that functions in trans to regulate Hox genes mammals....
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PMID: 19234521
PDF is available here.
PDF is available here.
Abstract
Denis Duboule is one of the most influential and highly-cited scientists in developmental biology. Born in Geneva in 1955, he holds dual Swiss and French nationality. His undergraduate studies in biology at the University of Geneva included research on mouse embryology. He later learned molecular te...
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PMID: 19557678
PDF is available here.
PDF is available here.
Abstract
I interviewed Cliff on the 3rd October, 2007, in his office at Harvard....
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PMID: 19557679
PDF is available here.
PDF is available here.
Abstract
We summarize the current understanding of how Hox gene clusters have been modified from basal lineages of deuterostomes to diverse taxa of vertebrates. Our parsimony reconstruction of Hox cluster architecture at various stages of vertebrate evolution highlights that the variation in Hox cluster stru...
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PMID: 19557682
PDF is available here.
PDF is available here.
Cells Tissues Organs (189)1-4 2009
Abstract
We used transgenic mice with a knock-in for Msx1 or Msx2. Msx expression was analyzed on whole-mount experiments on heterozygous mice. The results were confirmed by quantitative RT-PCR on mandible and tibia samples. Steady-state levels of Msx2 mRNA were determined at 2 ages, at postnatal day 14 and...
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PMID: 18769023
PDF is available here.
PDF is available here.
Abstract
We identified in silico the putative full complement of Irx genes in the sequenced genomes of 36 different species representative of the main metazoan lineages, including non bilaterian species, several arthropods, non vertebrate chordates, and a basal vertebrate, the sea lamprey. We performed exten...
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PMID: 19368711
PDF is available here.
PDF is available here.
Abstract
The DEF-like genes from Orchidaceae form four well-supported, ancient clades of orthologues. In contrast, orchid GLO-like genes form a single clade of ancient orthologues and recent paralogues. DEF-like genes from orchid clade 2 (OMADS3-like genes) are under less stringent purifying selection than t...
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PMID: 19383167
PDF is available here.
PDF is available here.
Abstract
We summarize recent progress in understanding the pathology and biology of this disease and in development of models for preclinical research. Our new understanding of this disease suggests new targets for therapeutic intervention and novel markers for early detection of disease....
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PMID: 19273186
PDF is available here.
PDF is available here.
Abstract
We define a gene regulatory network for Hoxa2, responsible for temporal and spatial expression in hindbrain development. Hoxa2 plays an important role in regulating the regional identity of rhombomere 2 (r2) and is the only Hox gene expressed in this segment. In this study, we found that a Hoxa2 cis...
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PMID: 19104046
PDF is available here.
PDF is available here.
Developmental Biology (324)2 2008
Abstract
We have generated Six3+/- ;Hesx1Cre/+ double heterozygous mice. Strikingly, these mice show marked dwarfism, which is first detectable around weaning, and die by the 5th-6th week of age. Thyroid and gonad development is also impaired in these animals. Analysis of Six3+/- ;Hesx1Cre/+ compound embryos...
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PMID: 18775421
PDF is available here.
PDF is available here.
Collegium Antropologicum (32)4 2008
Abstract
The 2nd to 4th digit ratio (2D:4D) is a sexually dimorphic biometric marker, related to prenatal estrogen and testosterone levels in utero, and determined genetically by the HOX genes. 2D:4D presents a population variation, which seems to be dependent on geographical position or ethnicity, and may r...
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PMID: 19149213
PDF is available here.
PDF is available here.
Genome Research (18)12 2008
Abstract
We made such predictions across the large, complex ceh-13/lin-39 locus and tested them transgenically. We also examined how prediction quality varied with different genomes and parameters in our comparisons. Specifically, we sequenced approximately 0.5% of the C. brenneri and C. sp. 3 PS1010 genomes...
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PMID: 18981268
PDF is available here.
PDF is available here.
Abstract
We have identified 102 homeobox genes in the typical insect of Lepidoptera, Bombyx mori, based on the newly assembled genome sequence with 9X coverage. These identified homeobox genes were categorized into nine classes including at least 74 families. The available ESTs and microarray data at present...
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PMID: 19280701
PDF is available here.
PDF is available here.
Abstract
We report here on the current knowledge of the role played by homeobox genes in normal and abnormal vasculogenesis and postulate a common molecular mechanism accounting for the involvement of homeobox genes in the regulation of the nuclear export of specific transcripts potentially capable of genera...
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PMID: 19013779
PDF is available here.
PDF is available here.
Abstract
We show that S and AN, which encode a homeobox transcription factor and an F-box protein, respectively, control inflorescence architecture by promoting successive stages in the progression of an inflorescence meristem to floral specification. S and AN are sequentially expressed during this gradual p...
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PMID: 19018664
PDF is available here.
PDF is available here.
Abstract
We conducted cDNA sequencing in diverse early vertebrates for members of homeobox-containing (Dlx and ParaHox) and other gene families that would serve as landmarks for genome duplications. Including these new sequences, we performed a molecular phylogenetic census using the maximum likelihood metho...
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PMID: 18842688
PDF is available here.
PDF is available here.
Genome Research (18)10 2008
Abstract
We used tiled microarrays to identify stable nucleosome positions along the HOX gene clusters in human cell lines. We show that nucleosome positions exhibit sequence properties and long-range organization that are different from those characterized in other organisms. Despite overall variability of...
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PMID: 18723689
PDF is available here.
PDF is available here.