Abstract
Osteoporosis is a serious worldwide epidemic. FRAX(®) is a web-based tool developed by the Sheffield WHO Collaborating Center team, that integrates clinical risk factors and femoral neck BMD and calculates the 10 year fracture probability in order to help health care professionals identify patients...
|
PMID: 21810531
PDF is available here.
John F JF de Groot,
Kathleen R KR Lamborn,
Susan M SM Chang,
Mark R MR Gilbert,
Timothy F TF Cloughesy,
Kenneth K Aldape,
Jun J Yao,
Edward F EF Jackson,
Frank F Lieberman,
H Ian HI Robins,
Minesh P MP Mehta,
Andrew B AB Lassman,
Lisa M LM Deangelis,
W K Alfred WK Yung,
Alice A Chen,
Michael D MD Prados and
Patrick Y PY Wen
Abstract
Antivascular endothelial growth factor (anti-VEGF) therapy is a promising treatment approach for patients with recurrent glioblastoma. This single-arm phase II study evaluated the efficacy of aflibercept (VEGF Trap), a recombinantly produced fusion protein that scavenges both VEGF and placental growt...
|
PMID: 21606416
PDF is available here.
Abstract
We analyzed 2,212 submitted results. Precision was highest for von Willebrand factor (vWF) antigen assays (coefficient of variation, 14%), which were performed predominantly by latex immunoassays, and lowest for ristocetin cofactor assays (coefficient of variation, 28%), which were increasingly repl...
|
PMID: 21571959
PDF is available here.
Abstract
We collected mesowear data for North American Equidae for the past 55.5 million years to test the association of molar height and dietary abrasion. Mesowear trends in horses are reflective of global cooling and associated vegetation changes. There is a strong correlation between mesowear and crown h...
|
PMID: 21385712
PDF is available here.
Abstract
We show that human-induced increases in greenhouse gases have contributed to the observed intensification of heavy precipitation events found over approximately two-thirds of data-covered parts of Northern Hemisphere land areas. These results are based on a comparison of observed and multi-model sim...
|
PMID: 21331039
PDF is available here.
Goodarz Danaei,
Mariel M Finucane,
John K Lin,
Gitanjali M Singh,
Christopher J Paciorek,
Melanie J Cowan,
Farshad Farzadfar,
Gretchen A Stevens,
Stephen S Lim,
Leanne M Riley,
Majid Ezzati and
Global Burden of Metabolic Risk Factors of Chronic Diseases Collaborating Group (Blood Pressure)
Abstract
We estimated worldwide trends in population mean systolic blood pressure (SBP).
We estimated trends and their uncertainties in mean SBP for adults 25 years and older in 199 countries and territories. We obtained data from published and unpublished health examination surveys and epide...
|
PMID: 21295844
PDF is available here.
Abstract
We focus on monarch butterflies (Danaus plexippus) and a protozoan parasite (Ophryocystis elektroscirrha) to investigate how host migration affects infectious disease processes. Previous work showed that parasite prevalence was lower among migratory than nonmigratory monarch populations; two explana...
|
PMID: 21618914
PDF is available here.
Abstract
We here propose the following combinations: Mattirolomyces spinosus comb. nov. (≡Terfezia spinosa), Stouffera longii gen. & comb. nov. (≡Terfezia longii) and Temperantia tiffanyae gen. & comb. nov. (≡Mattirolomyces tiffanyae). In addition, we describe a new species, Mattirolomyces mexicanus sp...
|
PMID: 21262987
PDF is available here.
Abstract
We utilized massively parallel pyrosequencing of a reduced representation library (RRL) and a random shotgun library (RSL) to generate a complete mitochondrial genome sequence and identify a large number of putative single nucleotide polymorphisms (SNPs) distributed throughout the white-tailed deer...
|
PMID: 21283515
PDF is available here.
Abstract
Several guidelines to reduce cardiovascular risk in diabetes patients exist in North America, Europe, and Australia. Their ability to achieve this goal efficiently is unclear.
|
PMID: 21283569
PDF is available here.
Abstract
The Tissue Engineering and Regenerative Medicine International Society-North America (TERMIS-NA) Industry Committee was formed in February 2009 to address the common roadblocks (i.e., hurdles) in the commercialization of tissue engineering/regenerative medicine products for its membe...
|
PMID: 20726816
PDF is available here.
Abstract
Until recently the only mode of mechanical circulatory support available in North America for use as bridge to cardiac transplantation in small children was extra-corporeal membrane oxygenation. However, since 2005 the Berlin Heart pediatric ventricular assist device has been increasingly widely used...
|
PMID: 21444059
PDF is available here.
Abstract
We identified a group formed by South African and another one by South American and European sequences. In the latter, the monophyletic group was formed by seven Argentinean sequences. In the NJ tree, we identified a group formed by six Argentinean sequences. The Tajima's test showed a D value of 1....
|
PMID: 20689314
PDF is available here.
Michael M Weisman,
Thomas J TJ Learch,
Xenofon X Baraliakos,
Vinod V Chandran,
Dafna D DD Gladman,
Siba P SP Raychaudhuri,
Huji H Xu,
Eduardo E Collantes-Estévez,
Janitzia J Vázquez-Mellado,
Philip J PJ Mease,
Joachim J Sieper,
Atul A AA Deodhar,
Robert A RA Colbert,
Daniel O DO Clegg and
Abstract
The Spondyloarthritis Research and Therapy Network (SPARTAN), founded in 2003 to promote research, education, and treatment of ankylosing spondylitis (AS) and related forms of spondyloarthritis (SpA), held its 7th Annual Research and Education Meeting in July 2009 in Houston, Texas. Current controver...
|
PMID: 21123334
PDF is available here.
Abstract
Abraham Flexner's 1910 report, Medical Education in the United States and Canada, was hardly noticed in the Netherlands, and though his 1925 book, Medical Education: A Comparative Study, was extensively discussed in the Dutch Medical Journal, it did not and could not affect medical education in the...
|
PMID: 20980851
PDF is available here.
Abstract
We identified publications by searching electronic databases, including MEDLINE (1966-October 2009) and EMBASE (1975-October 2009). Primary search criteria were age of menopause and climacteric symptoms. A sensitive analysis that excluded papers without full data was performed.
The median age at men...
|
PMID: 20690868
PDF is available here.
Abstract
We found that annual gross primary production (GPP) was the strongest correlate of richness (adjusted R2 = 0.55), with a quadratic model being the strongest model. The negative slope of the model was confirmed significantly negative at the highest energy levels. This finding demonstrates that there...
|
PMID: 21049886
PDF is available here.
Abstract
Questionnaires administered to practicing orthopedic and neurosurgical spine surgeons from North America, Europe, Asia, Australia, and New Zealand.
To determine diversity and commonalities in the treatment of spine trauma internationally.
Previous studies have had suggested that there is significant...
|
PMID: 20881459
PDF is available here.
Abstract
This is the seventh and last in a series of articles from Planetree, an international non profit organization founded in 1978 that's "committed to improving medical care from the patient's perspective." For more information, go to www.planetree.org. To register for a free Webinar based on this serie...
|
PMID: 20736711
PDF is available here.
Abstract
These data support the conclusion that ulceration is a predictive marker for response to adjuvant IFN therapy. Future studies to evaluate specifically the differential effect of IFN on patients with ulcerated melanomas may allow us to focus this therapy on patients most likely to benefit from it....
|
PMID: 20739846
PDF is available here.
Abstract
The role of natural selection in the evolution of human populations from Northeastern Eurasia was studied. Selection for the regions-specific haplogroup C was demonstrated.
|
PMID: 21061628
PDF is available here.
Abstract
We investigate the role of recombination in transposable element (TE) proliferation in the cyclical parthenogen, Daphnia pulex. Recombination provides a mechanism by which the rate of both TE gain and loss can be accelerated, a duality that has long intrigued many biologists interested in the influe...
|
PMID: 20356890
PDF is available here.
Abstract
The evolution of the eastern Asian and eastern North American disjunction of the witch-hazel genus Hamamelis L. (Hamamelidaceae) was examined through phylogenetic and biogeographic analyses. Phylogenetic relationships of all Hamamelis species were reconstructed using parsimony and Bayesian analyses...
|
PMID: 20171295
PDF is available here.
Abstract
We have seen an increasing trend of foreign data as part of clinical trial data submitted in new drug applications (NDA) to US Food and Drug Administration (FDA). To understand the design and analysis characteristics, we studied schizophrenia multi-regional clinical trials (MRCTs). The schizophrenia...
|
PMID: 20872622
PDF is available here.
Abstract
There has been limited investigation of the sexuality and sexual dysfunction in non-heterosexual subjects by the sexual medicine community. Additional research in these populations is needed.
To investigate and compare sexuality and sexual function in students of vary...
|
PMID: 20384941
PDF is available here.
Abstract
There has been limited investigation of the sexuality and sexual dysfunction in non-heterosexual subjects by the sexual medicine community. Additional research in these populations is needed.
To investigate and compare sexuality and sexual function in students of vary...
|
PMID: 20384941
PDF is available here.
Abstract
There has been limited investigation of the sexuality and sexual dysfunction in non-heterosexual subjects by the sexual medicine community. Additional research in these populations is needed.
To investigate and compare sexuality and sexual function in students of vary...
|
PMID: 20384941
PDF is available here.
Abstract
The early results of this study show a low incidence of valve-related adverse events and excellent hemodynamic performance. Continued follow-up is needed to determine if long-term durability in North American patients is comparable to that in previous reports on the durability of the Mitroflow valve...
|
PMID: 20609765
PDF is available here.
Abstract
Median thickness of melanoma was 5.6 mm, and patients were followed up for a median of 50 months. The SLNs were tumor positive in 100 patients (41.7%); 18% of these had additional positive nodes on completion lymphadenectomy. Extremity tumor location (risk ratio, 1.66; 95% confidence interval, 1.24-...
|
PMID: 20644123
PDF is available here.
Abstract
We used two mitochondrial loci (nicotinamide adenine dinucleotide dehydrogenase subunit 4 and cytochrome oxidase II) and a nuclear locus (28S-D2 spacer) for a total of 1337 bp to evaluate the relationships among the four subspecies of Aedes (Finlaya) japonicus Theobald. Ae. j. japonicus was recently...
|
PMID: 20695267
PDF is available here.
Abstract
We explore the interaction between two of the most widespread earthworm invaders in the world (Asian Amynthas agrestis and European Lumbricus rubellus) and study the effects of species invasiveness and habitat invasibility separately through an alternative approach of "third habitat" in Tennessee, U...
|
PMID: 20715629
PDF is available here.
Abstract
We demonstrate how direct and indirect consumer effects prevent recruitment by Quercus garryana, a keystone savanna species of northwestern North America. Foremost, intense herbivory by mostly exotic small mammals severely damaged or killed 100% of unprotected seedlings during winter. Many damaged s...
|
PMID: 20715631
PDF is available here.
S E Jamieson,
A L Peixoto-Rangel,
A C Hargrave,
L-A de Roubaix,
E J Mui,
N R Boulter,
E N Miller,
S J Fuller,
J S Wiley,
L Castellucci,
K Boyer,
R G Peixe,
M J Kirisits,
L de Souza Elias,
J J Coyne,
R Correa-Oliveira,
M Sautter,
N C Smith,
M P Lees,
C N Swisher,
P Heydemann,
A G Noble,
D Patel,
D Bardo,
D Burrowes,
D McLone,
N Roizen,
S Withers,
L M G Bahia-Oliveira,
R McLeod and
J M Blackwell
Abstract
We examined polymorphisms at P2RX7 in 149 child/parent trios from North America. We found association (FBAT Z-scores +/-2.429; P=0.015) between the derived C(+)G(-) allele (f=0.68; OR=2.06; 95% CI: 1.14-3.75) at single-nucleotide polymorphism (SNP) rs1718119 (1068T>C; Thr-348-Ala), and a second syno...
|
PMID: 20535134
PDF is available here.
Abstract
We investigated the growth performance and life history characteristics of plants from 12 European and 24 North American (12 diploid, 12 tetraploid) populations in a common garden experiment involving two nutrient and two calcium treatments. Twelve plants per population were grown in pots for two se...
|
PMID: 20238128
PDF is available here.
Abstract
We investigated the growth performance and life history characteristics of plants from 12 European and 24 North American (12 diploid, 12 tetraploid) populations in a common garden experiment involving two nutrient and two calcium treatments. Twelve plants per population were grown in pots for two se...
|
PMID: 20238128
PDF is available here.
Abstract
We investigated the growth performance and life history characteristics of plants from 12 European and 24 North American (12 diploid, 12 tetraploid) populations in a common garden experiment involving two nutrient and two calcium treatments. Twelve plants per population were grown in pots for two se...
|
PMID: 20238128
PDF is available here.
Abstract
We investigated the growth performance and life history characteristics of plants from 12 European and 24 North American (12 diploid, 12 tetraploid) populations in a common garden experiment involving two nutrient and two calcium treatments. Twelve plants per population were grown in pots for two se...
|
PMID: 20238128
PDF is available here.
Abstract
We investigated the growth performance and life history characteristics of plants from 12 European and 24 North American (12 diploid, 12 tetraploid) populations in a common garden experiment involving two nutrient and two calcium treatments. Twelve plants per population were grown in pots for two se...
|
PMID: 20238128
PDF is available here.
Abstract
We investigated the growth performance and life history characteristics of plants from 12 European and 24 North American (12 diploid, 12 tetraploid) populations in a common garden experiment involving two nutrient and two calcium treatments. Twelve plants per population were grown in pots for two se...
|
PMID: 20238128
PDF is available here.
Abstract
We investigated the growth performance and life history characteristics of plants from 12 European and 24 North American (12 diploid, 12 tetraploid) populations in a common garden experiment involving two nutrient and two calcium treatments. Twelve plants per population were grown in pots for two se...
|
PMID: 20238128
PDF is available here.
Abstract
We investigated the growth performance and life history characteristics of plants from 12 European and 24 North American (12 diploid, 12 tetraploid) populations in a common garden experiment involving two nutrient and two calcium treatments. Twelve plants per population were grown in pots for two se...
|
PMID: 20238128
PDF is available here.
Abstract
We investigated the growth performance and life history characteristics of plants from 12 European and 24 North American (12 diploid, 12 tetraploid) populations in a common garden experiment involving two nutrient and two calcium treatments. Twelve plants per population were grown in pots for two se...
|
PMID: 20238128
PDF is available here.
Abstract
We investigated the growth performance and life history characteristics of plants from 12 European and 24 North American (12 diploid, 12 tetraploid) populations in a common garden experiment involving two nutrient and two calcium treatments. Twelve plants per population were grown in pots for two se...
|
PMID: 20238128
PDF is available here.
Abstract
We investigated the growth performance and life history characteristics of plants from 12 European and 24 North American (12 diploid, 12 tetraploid) populations in a common garden experiment involving two nutrient and two calcium treatments. Twelve plants per population were grown in pots for two se...
|
PMID: 20238128
PDF is available here.
Abstract
We investigated the growth performance and life history characteristics of plants from 12 European and 24 North American (12 diploid, 12 tetraploid) populations in a common garden experiment involving two nutrient and two calcium treatments. Twelve plants per population were grown in pots for two se...
|
PMID: 20238128
PDF is available here.
Abstract
We investigated the growth performance and life history characteristics of plants from 12 European and 24 North American (12 diploid, 12 tetraploid) populations in a common garden experiment involving two nutrient and two calcium treatments. Twelve plants per population were grown in pots for two se...
|
PMID: 20238128
PDF is available here.
Abstract
We investigated the growth performance and life history characteristics of plants from 12 European and 24 North American (12 diploid, 12 tetraploid) populations in a common garden experiment involving two nutrient and two calcium treatments. Twelve plants per population were grown in pots for two se...
|
PMID: 20238128
PDF is available here.
Abstract
We investigated the growth performance and life history characteristics of plants from 12 European and 24 North American (12 diploid, 12 tetraploid) populations in a common garden experiment involving two nutrient and two calcium treatments. Twelve plants per population were grown in pots for two se...
|
PMID: 20238128
PDF is available here.
Abstract
We investigated the growth performance and life history characteristics of plants from 12 European and 24 North American (12 diploid, 12 tetraploid) populations in a common garden experiment involving two nutrient and two calcium treatments. Twelve plants per population were grown in pots for two se...
|
PMID: 20238128
PDF is available here.
Abstract
We investigated the growth performance and life history characteristics of plants from 12 European and 24 North American (12 diploid, 12 tetraploid) populations in a common garden experiment involving two nutrient and two calcium treatments. Twelve plants per population were grown in pots for two se...
|
PMID: 20238128
PDF is available here.
Abstract
We investigated the growth performance and life history characteristics of plants from 12 European and 24 North American (12 diploid, 12 tetraploid) populations in a common garden experiment involving two nutrient and two calcium treatments. Twelve plants per population were grown in pots for two se...
|
PMID: 20238128
PDF is available here.