Abstract
The objective of the present work was to develop indications for the combined treatment of patients presenting with osteoarthrosis including the use of peloid applications and intramuscular injections of alflutop. The study was based at Yakty-Kul' health resort and included 94 patients at the age fro...
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PMID: 21584955
PDF is available here.
Abstract
The study of the fitness for military service in the Republic of Bashkortostan according to the medical examination results has shown that the common morbidity in draft-age adolescents increased in four times. More significant risk factors determining the growth of chronic non-infectious diseases in...
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PMID: 21089432
PDF is available here.
Abstract
The research was aimed at studying molecular genetics basis of human longevity. The genotyping of polymorphisms in genes of interleukin 6 (IL-6, 7p21, -572G>C, rs1800796), 10 (IL-10, 1q31-q32, -627C>A, rs1800792), 12, (IL-12B, 5q31.1-q33.1, -1159C>A) and tumor necrosis factor-alpha (...
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PMID: 21137202
PDF is available here.
Abstract
The research was aimed at studying molecular genetics basis of human longevity. The genotyping of polymorphisms in genes of interleukin 6 (IL-6, 7p21, -572G>C, rs1800796), 10 (IL-10, 1q31-q32, -627C>A, rs1800792), 12, (IL-12B, 5q31.1-q33.1, -1159C>A) and tumor necrosis factor-alpha (TNF-alpha, 6p21....
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PMID: 21137202
PDF is available here.
Abstract
We did not find any association of Leu432Val CYP1B1 gene with chronic obstructive pulmonary disease....
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PMID: 20198857
PDF is available here.
Abstract
The article presents results of neurophysiologic study of neuro-muscular disorders in skeletal and muscular diseases in oil industry workers. Findings are that intrasystemic relationships in nervous system of segmentary and suprasegmentary levels are involved into neuro-muscular disorders formation....
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PMID: 20480815
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Abstract
Studies covered changes in serum vitamin antioxidant content in patients with hemorrhagic fever with renal syndrome male workers, in accordance with occupational activity type. Findings are that during the disease and convalescence period the drivers examined demonstrated reliably lower levels of vi...
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PMID: 20480967
PDF is available here.
Abstract
According to psychobiological model of personality proposed by Cloninger, personality traits characterizing enhanced tendency to novel stimuli, impulsivity and sociability are influenced by dopaminergic system functioning. The present study considered both the main effect of two polymorphic loci (VN...
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PMID: 19769301
PDF is available here.
Abstract
In this study, frequencies of the polymorphic variants of the genes encoding antioxidant enzymes, GSTM1, GSTT1, GSTP1, CAT, GPX1, NQO1, SOD1, and SOD3 were examined in three ethnic groups of healthy subjects from the Republic of Bashkortostan (Russians, Tatars, and Bashkirs). An association of these...
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PMID: 19705749
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S Sh Murzabaeva,
R A Zinchenko,
Ia I Grinberg,
V A Galkina,
O V Khlebnikova,
E L Dadali,
V P Fedotov,
G I El'chinova,
I G Terekhovskaia,
I M Khidiiatova,
E K Khusnutdinova and
E K Ginter
Abstract
We present the data obtained during medical genetic examination of the population of five districts of Bashkortostan Republic (Burzyanskii, Baimakskii, Abzelilovskii, Salavatskii, and Arkhangelskii) populated with 168050 persons including 135748 Bashkirs. The study involved all the population of the...
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PMID: 19507708
PDF is available here.
Abstract
The marriage migration structure of the populations of six districts of Bashkortostan Republic has been studied. The rates of assortative marriages in Bashkirs, Tatars, and Russians are 1.02-2.71, 1.30-5.99, and 2.14-7.50, respectively; the endogamy indices are 0.58-0.97, 0.90, and 0.68, respectivel...
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PMID: 19382695
PDF is available here.
Abstract
Enzymes of biotransformation system involved in the metabolism of exogenous and endogenous compounds are effective mechanism of protection from negative environmental factors. Decreasing activity or insufficient synthesis of biotransformation system enzymes caused by genetic polymorphism form the ri...
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PMID: 20088379
PDF is available here.
Abstract
The authors studied influence of occupational environment and work process factors on health of workers engaged into oil extraction. Analysis covered 7487 oil industry workers. Locomotory system and peripheral nervous system diseases, arterial hypertension, ENT diseases, gastro-intestinal disorders...
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PMID: 19810182
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Abstract
The authors analysed occupational morbidity in chemical industry workers of Bashkortostan republic over 1997-2006, including "Steklonit" JSC workers, presented hygienic evaluation of work conditions. Evidence is that occupational morbidity level in operators of continuous glass fiber production is c...
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PMID: 19803359
PDF is available here.
Abstract
The authors studied occupational morbidity accumulated over 35 years in oil industry workers of Bashkortostan Republic. Leading place in morbidity structure is occupied by diseases caused by physical overload and certain organs and systems overstrain (81.5%), by physical factors (10.6%). Occupationa...
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PMID: 19943530
PDF is available here.
Abstract
The authors analyzed occupational morbidity changes in agricultural workers of Bashkortostan Republic over 1997 2006, in relation to occupation, sex, age, length of service, work conditions and type. Findings are signs of elevated occupational morbidity level. Criteria of occupational risk for agric...
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PMID: 20151594
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Abstract
I antigens with uveitis in patients from the Republic of Bashkortostan it has been proven that HLA B27 and B47 and haplotype A2B47 should be considered to be the markers responsible for the occurrence of uveitis in systemic and syndromic diseases. The greatest relative risk of herpetic anterior and...
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PMID: 19566039
PDF is available here.
Abstract
The authors describe unique natural therapeutic factors of the Yangan-Tau health resort including its climatic features, drinking mineral waters, steam-and-air baths, etc. Modern approaches to the exploitation of these resources for the management of various pathological conditions are discussed.
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PMID: 19639696
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Abstract
The integrated assessment of urban general educational establishments has revealed that teaching conditions at most of them do not meet the requirements of hygiene and the natural science bases of age-related psychophysiology. Only at the recently commissioned schools, the teaching conditions are re...
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PMID: 19514293
PDF is available here.
Abstract
In three ethnic groups from the Republic of Bashkortostan, Russians (N = 451), Tatars (N= 333), and Bashkirs (N= 171), allele, genotype, and haplotype frequency distribution patterns of the CYP1A1 gene single nucleotide polymorphisms, A2455G and T33801C, were investigated. Substantial interethnic di...
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PMID: 19178087
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Abstract
Hereditary motor and sensory neuropathy type 1X (HMSN 1X) is the second most frequent form of demyelinating polyneuropathies and is caused by mutations in the gene for connexin 32 protein (Cx32, GJB1). The contribution of HMSN 1X to the structure of HMSN in the Republic of Bashkortostan was determin...
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PMID: 19062535
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Abstract
Molecular genetic analysis of congenital adrenal hyperplasia (CAH) was carried out in 59 patients from the Republic of Baskortostan, which belonged to two main groups. The first group was represented by 35 patients with salt wasting form of the disease, and the second group was comprised of 24 patie...
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PMID: 19062540
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Abstract
The extent and spatial pattern of genetic variation at polymorphic allozyme loci in a population of pedunculate oak Quercus robur from the Bashkir Transural region was investigated using autocorrelation analysis. In the plantation examined, statistically significant local concentration of most of th...
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PMID: 18825965
PDF is available here.
Abstract
We found that the IL10 -627 *C/*C genotype was associated with decreased risk of hypertension (OR = 0.64, P = 0.035). IL6 genotypes and allele distribution did not differ significantly between subjects with and without hypertension, but the IL6 -572 *G/*G genotype frequency was found to be significa...
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PMID: 18163209
PDF is available here.
Abstract
We suggest that the increased expression of MMP9 gene caused by genetic polymorphism in the gene promoter is important in the early development of serious complications of the disease....
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PMID: 18619044
PDF is available here.
Abstract
The paper assesses c5266dupC (5382insC) mutation incidence among breast cancer patients, residents of the Republic of Bashkorstan and Tyumen Region. It appeared as high as 4%.
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PMID: 18416054
PDF is available here.
Abstract
Electrocardiographic and echocardiographic parameters were studied in 364 patients admitted to the department of thoracic surgery of Bashkirian Medical University clinic in 1997-2006. The patients had hemorrhagic shock due to acute traumatic blood loss or long operative intervention with massive hem...
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PMID: 19198265
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Abstract
We did not find any differences in the genotypes and haplotypes frequency distributions of the CYP1A2 gene within the patients and healthy groups in Russian ethnic group. We also did not find any association of CYP1A1 gene with COPD in ethnic groups of Bashkortostan....
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PMID: 18389617
PDF is available here.
Abstract
The author summarized and analyzed results of psychosocial studies in five occupational groups (oilmen, glass production workers, doctors of all specialities, surgeons, teachers) through the same questionnaire. Finding is high significance of fear connected with losing the workplace for workers, and...
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PMID: 18688968
PDF is available here.
Abstract
The authors analyzed occupational morbidity in major economic branches of Bashkortostan Republic over 2002-2006, in comparison with Russian Federation, performed ranking of the economic branches according to the share of accumulated occupational morbidity, gave brief hygienic evaluation of work cond...
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PMID: 18589901
PDF is available here.
Abstract
The author performed complex hygienic and psychosocial study of work conditions and health state of glass production workers and of teachers in comprehensive schools. Finding was high probability of occupational diseases due to high work load and work intensity.
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PMID: 18589902
PDF is available here.
Abstract
The article deals with results of evaluated metals intake by residents of Ufa - major industrial city. Findings are that in absence of occupational exposure to heavy metal salts human health becomes more vulnerable to ecologic influence. Main sources of heavy metals intake by humans are foods provid...
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PMID: 18589723
PDF is available here.
Abstract
The authors demonstrated relationship between alimentation dependent diseases among adult population of the Republic and nutritional traits of the population, defined major directions of program to optimize nutrition of the population.
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PMID: 18589724
PDF is available here.
Abstract
The authors analyzed materials of thorough medical examinations among ore-dressing and processing enterprise workers. All studied workers appeared to have increased risk of locomotor diseases and connective tissue disorders, ailments of respiratory tract, nervous system, ENT organs, digestive system...
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PMID: 18589725
PDF is available here.
Abstract
The authors presented results of studies concerning oral cavity state and mineral homeostasis in agriculture workers with diagnosed nephrolithiasis. Severity of nephrolithiasis appeared to correlate with oral cavity state.
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PMID: 18589903
PDF is available here.
Abstract
The paper presents data on the content of chemical elements in the snow blanket, water sources, soil, and agricultural products in the Uchaly and Baimak districts of the Republic of Bashkortostan. The integrated pollution of environmental objects and the content of metals in the biological environme...
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PMID: 18365466
PDF is available here.
Abstract
We evaluated familial correlations and performed segregation analysis. Results of our study suggest the familial aggregations of TOSS variation in the Chuvashian pedigrees. In a segregation analysis we found a significant major gene (MG) effect in the individual's TOSS with a dominant most parsimoni...
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PMID: 17588211
PDF is available here.
Abstract
Data on several populations of Russia have been used to demonstrate that the change in the endogamy index detected in the second half of the 20th century is not global. Migration activity remains high in populations with relatively low endogamy indices, and their endogamy does not change with time....
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PMID: 17958317
PDF is available here.
Abstract
The paper presents the results of sanitary and parasitological studies of natural portable water, sewage, its deposits, soil, and other environmental objects in the Republic of Bashkortostan. The high extensive rates (14.2 to 91.6%) of semination with helminth eggs and pathogenic intestinal protozoa...
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PMID: 17657953
PDF is available here.
Abstract
The analysis of the dynamics of the oncological mortality in the Republic of Bashkortostan from 1989 to 2005 was carried out. It is revealed that since 1992 the oncological mortality occupies the third position in the structure of population morbidity (10.4-14%). The minor trend to the increase of t...
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PMID: 17674529
PDF is available here.
Abstract
We did not succeed in detecting the local root nodule bacteria that were either initially able to infect oriental goat's rue or had adapted to infecting this species due to various genetic rearrangements....
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PMID: 17619578
PDF is available here.
Abstract
We found that sex differences regarding the rate of OSS change began in the fifth decade, but became statistically significant only in the sixth and seventh decades. Thereafter, the rate of OSS change again became virtually equal between sexes....
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PMID: 17160987
PDF is available here.
Abstract
Polymerase chain reaction was used to study the association of polymorphic markers I/D of the angiotensin-converting enzyme gene (ACE) and A1166C of the angiotensin II type 1 receptor gene (AT2R1) with chronic heart failure (CHF) in Russian and Tatar patients that had had myocardial infarction. In R...
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PMID: 17326392
PDF is available here.
Abstract
Clinical presentations and course of multiple sclerosis (MS) have been studied in ethnic groups of Bashkortostan Republic. An analysis of 4 groups of patients, 234 Tartars, 80 Bashkirs, 22 Chuvashes and 237 Russians, revealed that the prevalence of MS was the least in the Bashkirs--3 times less than...
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PMID: 17172230
PDF is available here.
Abstract
The distribution of alleles and genotypes of vitamin D-binding protein (DBP) gene has been studied in patients with Chronic Obstructive Pulmonary Disease (COPD, n = 298) and healthy individuals (n = 237) from two ethnic groups (Tatars and Russians) living in Republic Bashkortostan. Statistically sig...
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PMID: 16637263
PDF is available here.
Abstract
The article contains results of analysis covering lifestyle and health state of doctors according to questionnaires among 6077 doctors of Bashkortostan republic in 2002-2003. The author proved that nowadays doctors are characterized by low quality of life and health, their lifestyle could not be con...
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PMID: 17300051
PDF is available here.
Abstract
The article describes effects of unique thermal springs of Yangan-Tau mountain in patients with locomotor diseases. Effects of gas, steam and thermal factors of the water from the above springs were studied in patients with rheumatoid arthritis who took baths in the sanatorium Yangan-Tau. Changes in...
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PMID: 16752740
PDF is available here.
Abstract
We used three different transmission disequilibrium tests and obtained highly significant association signals. Alleles of the upstream microsatellite marker as well as several single-nucleotide polymorphism haplotypes consistently revealed the association. Thus, our data highlights variability of EN...
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PMID: 16207325
PDF is available here.
Abstract
A genetic association of the ENPP1 gene with primary hand osteoarthritis was recently reported in this journal. ENPP1 encodes an enzyme that regulates soft tissue calcification. The study as it stands is far from complete because the actual causal variant(s) within ENPP1 has not been identified and...
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PMID: 16207345
PDF is available here.