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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Biotin (0):
Recent article
Biotin
Abstract
Whereas older literature has focused on the relationship among nutritional deficiency, malnutrition and poverty, recent research has identified additional patient populations that are at risk for developing nutritional deficiencies. These populations include premature infants, patients with long-ter...
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PMID: 19966568
PDF is available here.
PDF is available here.
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Abstract
We report zinc and biotin deficiencies after pancreaticoduodenectomy in a 16 year old female presenting clinically with marked alopecia, total body hair loss, dry skin with scales, and maculopathy with significant vision loss. These micronutrient deficiencies likely occurred due to resection of the...
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PMID: 20690572
PDF is available here.
PDF is available here.
Abstract
A magnetic modulation biosensing system (MMB) [1,2] rapidly and homogeneously detected biological targets at low concentrations without any washing or separation step. When the IL-8 target was present, a 'sandwich'-based assay attached magnetic beads with IL-8 capture antibody to streptavidin couple...
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PMID: 20616784
PDF is available here.
PDF is available here.
Audio, Transactions of the IRE Professional Group on (Chapter 13) 2010
Abstract
A method is described for the quantitative analysis of protein-protein interactions using the flow cytometry protein interaction assay (FCPIA). This method is based upon immobilizing protein on a polystyrene bead, incubating these beads with a fluorescently labeled binding partner, and assessing the...
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PMID: 20069525
PDF is available here.
PDF is available here.
Abstract
Cells have evolved sophisticated molecular machinery, such as kinesin motor proteins and microtubule filaments, to support active intracellular transport of cargo. While kinesins tail domain binds to a variety of cargoes, kinesins head domains utilize the chemical energy stored in ATP molecules to s...
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PMID: 21085103
PDF is available here.
PDF is available here.
Abstract
We describe a method for observing real time replication of individual DNA molecules mediated by proteins of the bacteriophage replication system. Linearized lambda DNA is modified to have a biotin on the end of one strand, and a digoxigenin moiety on the other end of the same strand. The biotinylat...
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PMID: 20332766
PDF is available here.
PDF is available here.
Abstract
Using this biotin label-based antibody array technology, the expression levels of 507 human, 308 mouse and 90 rat target proteins can be simultaneously detected, including of cytokines, chemokines, adipokines, growth factors, angiogenic factors, proteases, soluble receptors, soluble adhesion molecul...
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PMID: 20551245
PDF is available here.
PDF is available here.
Abstract
We used numerous stably transfected Madin-Darby canine kidney cell models, replacing serine residues with either alanine (A), which prevents phosphorylation, or aspartic acid (D), which mimics the charged state of phosphorylated AQP2, to address whether phosphorylation is involved in regulation of (...
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PMID: 19966308
PDF is available here.
PDF is available here.
Abstract
The PII protein is a signal integrator involved in the regulation of nitrogen metabolism in bacteria and plants. Upon sensing of cellular carbon and energy availability, PII conveys the signal by interacting with target proteins, thereby modulating their biological activity. Plant PII is located to...
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PMID: 20018655
PDF is available here.
PDF is available here.
Abstract
We studied the effects of biotin starvation and replenishment in 3 distantly related eukaryotes: yeast Saccharomyces cerevisiae, nematode Caenorhabditis elegans and rat Rattus norvegicus.
Biotin starvation was produced in Wistar rats, in C. elegans N2 and S. cerevisiae W303A fed with...
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PMID: 20798549
PDF is available here.
PDF is available here.
Abstract
We refer to this technique as transmission at a low frequency and reception at a high frequency (TLRH). Using this wideband, transient echo, we have developed and implemented a targeted imaging technique incorporating a multifrequency colinear array and the Siemens Antares imaging system. The multif...
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PMID: 20178897
PDF is available here.
PDF is available here.
Abstract
Surface plasmon resonance (SPR) is a highly sensitive method for the detection of molecular interactions. One interacting partner is immobilized on the sensor chip surface while the other is injected across the sensor surface. This chapter focuses on high-affinity immobilization of protein substrate...
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PMID: 20217614
PDF is available here.
PDF is available here.
Abstract
A fast and simple chromatographic method to determine biotin in foods is presented. Biotin is extracted using papain (60 degrees C, 1 h). After pH adjustment and filtration, biotin is determined by LC with fluorescence detection using postcolumn reagent avidin-FITC (avidin labeled with fluorescein i...
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PMID: 21140662
PDF is available here.
PDF is available here.
Abstract
To develop a novel high-throughput tool for monitoring carbohydrate-protein interactions, carbohydrate or glycoprotein microarrays have been prepared for binding with lectins. The interaction events are marked by attachment of fluorescent dyes and gold nanoparticles. The attachment of the fluorescen...
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PMID: 19882126
PDF is available here.
PDF is available here.
Abstract
We describe a synthetic approach to polyacrylamide-based glycoconjugates with biotin tag, with special emphasis to development of carbohydrate biosensors and arrays....
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PMID: 19882121
PDF is available here.
PDF is available here.
Abstract
Oral submucous fibrosis (OSF) is a form of pathological fibrosis affecting the oral mucosa. There is compelling evidence to implicate the habitual chewing of areca nut with the development of OSF. Because collagens are the major structural components of connective tissues, including oral submucosa,...
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PMID: 20930336
PDF is available here.
PDF is available here.
Abstract
We aimed to determine the somatotopy and morphological features of the thalamocortical neurons within mouse VL. Retrograde tracing studies revealed that whisker-related VL neurons were found relatively anterior and medial to those labeled following injection of retrograde tracer into hindpaw motor a...
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PMID: 20141408
PDF is available here.
PDF is available here.
Neuroscience (165)2 2010
Abstract
We aimed to characterize non-fornical forebrain projections from this region that might mediate the PPI-disruptive effects of the ventral temporal lobe. Electrolytic lesions of the precommissural fornix in male Sprague-Dawley rats were followed by infusions of fluorogold into the mPFC or by infusion...
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PMID: 19854244
PDF is available here.
PDF is available here.
Abstract
We report the crystal structures of the biotin carboxylase (BC) domain of human ACC2 phosphorylated by AMP-activated protein kinase (AMPK). The phosphorylated Ser222 binds to the putative dimer interface of BC, disrupting polymerization and providing the molecular mechanism of inactivation by AMPK....
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PMID: 19900410
PDF is available here.
PDF is available here.
Abstract
A novel method to significantly enhance fluorescence resonance energy transfer (FRET) signal which occurred from fluoresceine isothiocyanate (FITC) to Dylight 549 was studied in this paper. Streptavidin was labeled with the donor fluorophore FITC and biotinamide was conjugated to the acceptor Dyligh...
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PMID: 19836503
PDF is available here.
PDF is available here.
Journal of Neuroscience (29)48 2009
Abstract
We examined the molecular mechanism that controls photoreceptor coupling in zebrafish retina. Connexin 35 (homologous to Cx36 of mammals) was found at both cone-cone and rod-cone gap junctions. Photoreceptors showed strong Neurobiotin tracer coupling at night, extensively labeling the network of con...
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PMID: 19955370
PDF is available here.
PDF is available here.
Abstract
Like children with profound biotinidase deficiency, children with partial biotinidase deficiency are symptom-free at birth. However, the subsequent occurrence of symptoms of profound biotinidase deficiency in our patient with partial deficiency suggests that biotin therapy for this condition may be...
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PMID: 20333870
PDF is available here.
PDF is available here.
Proteomics (9)24 2009
Abstract
We introduce an integrated method, biotin tagging coupled with amino acid-coded mass tagging, for highly sensitive and accurate screening of mammalian protein-protein interactions. Without the need of establishing a stable cell line, using a short peptide tag which could be specifically biotinylated...
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PMID: 19834888
PDF is available here.
PDF is available here.
médecine/sciences (25)12 2009
Abstract
Monoclonal antibodies have emerged as a very successful class of therapeutic agents. In their native format, monoclonal antibodies are monospecific in that they recognize only one epitope, but their Fc domain also binds to FcfR-expressing cells. Attempts to improve the cytotoxicity of antibodies, pa...
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PMID: 20035697
PDF is available here.
PDF is available here.
Thrombosis and Haemostasis (102)5 2009
Abstract
The elucidation of the structure of the antithrombin binding sequence in heparin has given a large impulse to the rational design of heparin related drugs. De novo chemical synthesis of the corresponding pentasaccharide as well as simplified analogues has provided very specific, antithrombin-mediate...
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PMID: 19888512
PDF is available here.
PDF is available here.