Find your PDFs fast.
Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Purpura, Thrombocytopenic (0):
Recent article
Purpura, Thrombocytopenic
A case of nocardiasis complicated with meningitis in a patient with immune thrombocytopenic purpura.
Abstract
We report a 25-year-old male patient who presented with nocardial pneumonia and meningitis without brain abscess. He was diagnosed as immune thrombocytopenic purpura and methyl prednisolone was started 5 weeks previously. Nocardia spp. was obtained from his cerebrospinal fluid culture, but he died a...
|
PMID: 19858711
PDF is available here.
PDF is available here.
| < More recent | Older article > |
Acta clinica Belgica (65)1 2010
Abstract
We describe the case of a 76-year-old male presenting a thrombocytopenia at the diagnosis of Hodgkin disease. Basing on bone marrow biopsy and evolution, we diagnosed an immune thrombocytopenia and treated with intravenous gammaglobulins. The platelet count normalized in a few days under this therap...
|
PMID: 20373597
PDF is available here.
PDF is available here.
Klinicheskaia meditsina (88)5 2010
Abstract
Iatrogenic blood diseases are a primary concern for both patients and physicians. Pathology of blood coagulation system associated with pharmacotherapy has been studied in Samara regional Hemostasiological Centre during the last 30 years. A clinical case of secondary iatrogenic thrombopenic purpura...
|
PMID: 21089462
PDF is available here.
PDF is available here.
Transfusion (50)1 2010
Abstract
Abstract
Helicobacter pylori infection is implicated in the pathogenesis of extradigestive diseases such as acne rosacea and idiopathic chronic urticaria and autoimmune diseases such as autoimmune gastric atrophy, rheumatoid arthritis, anti phospholipid antibody syndrome, autoimmune thyroiditis, Sjoegren syn...
|
PMID: 20170006
PDF is available here.
PDF is available here.
Abstract
Prescrire international (18)104 2009
Abstract
Abstract
We present a case of a patient with newly diagnosed, biopsy-proven metastatic pancreatic adenocarcinoma with new-onset immune thrombocytopenic purpura. The patient's platelet count returned to normal limits after being treated with oral corticosteroid therapy. In conclusion, immune thrombocytopenic...
|
PMID: 20131688
PDF is available here.
PDF is available here.
Ugeskrift for laeger (171)49 2009
Abstract
The thrombotic microangiopathic diseases, which include acquired and congenital TTP and HUS, are most frequently acute disease entities. Untreated, these diseases are associated with a lethal course in many cases. Deficiency of the von Willebrand cleaving enzyme, ADAMTS13, is a decisive pathophysiol...
|
PMID: 19954703
PDF is available here.
PDF is available here.
Abstract
We speculated that she had secondary ITP (ITP-like syndrome) associated with cancer. Only 11 cases of lung cancer with secondary ITP have ever been reported, 4 cases of which attained complete response of cancer and complete remission of ITP by anti-cancer therapy. Therapeutic procedures employed we...
|
PMID: 19994601
PDF is available here.
PDF is available here.
Medizinische Klinik (104)5 2009
Abstract
Journal of Immunology (182)3 2009
Abstract
These results provide insight into the mechanism of CRP regulatory activity in autoimmunity and suggest a potential new therapeutic approach to ITP....
|
PMID: 19155486
PDF is available here.
PDF is available here.
Terapevticheskii arkhiv (81)11 2009
Abstract
The clinical manifestations of hemostatic disorders at the height of ARL were characterized by the appearance of typhoid maculopapular rashes in 91.4% of the patients, solitary elements of which were transformed to petechiae in 20% of cases. At convalescence (on day 10.2 +/- 1.3 of the disease), all...
|
PMID: 20141010
PDF is available here.
PDF is available here.
Abstract
Abstract
We describe a patient with recently diagnosed AIDS who presented to the emergency department with hemorrhagic papules and shortness of breath. She was found to be severely thrombocytopenic, and a Tzanck smear revealed multinucleate giant cells. She received a diagnosis of immune thrombocytopenic pur...
|
PMID: 19181029
PDF is available here.
PDF is available here.
Abstract
The presenting features, diagnostic evaluation, seasonal variation and management performed in 110 children with immune thrombocytopenic purpura (ITP) attending at two tertiary level hospitals were evaluated. A peak incidence of children with ITP was observed during the month of June, July and the f...
|
PMID: 19476255
PDF is available here.
PDF is available here.
Abstract
We have successfully generated an animal model of human ITP via intraperitoneal injection of anti-platelet antibody into the Balb/c mouse. Platelet counts were dropped dramatically in animals that received antibody injection within 4 h, maintained at the minimum level for a period of 44 h, started t...
|
PMID: 19022200
PDF is available here.
PDF is available here.
Liver International (28)9 2008
Abstract
Abstract
New England Journal of Medicine (359)17 2008
Abstract
In patients with early, relapsing-remitting multiple sclerosis, alemtuzumab was more effective than interferon beta-1a but was associated with autoimmunity, most seriously manifesting as immune thrombocytopenic purpura. The study was not powered to identify uncommon adverse events. (ClinicalTrials.g...
|
PMID: 18946064
PDF is available here.
PDF is available here.
Abstract
von Willebrand factor (VWF) is a multimeric plasma protein that mediates platelet adhesion and aggregation at sites of vascular injury and also acts as a protective carrier of factor VIII. Although the acquired or inherited deficiency of VWF is associated with a bleeding tendency, there is increasin...
|
PMID: 19085767
PDF is available here.
PDF is available here.
Abstract
Four patients with acquired amegakaryocytic thrombocytopenic purpura, who had failed corticosteroids, intravenous immunoglobulin and cyclophosphamide therapy, were treated with antithymocyte globulin, followed by cyclosporin. Three patients achieved complete remission in 28-178 days and the response...
|
PMID: 18626728
PDF is available here.
PDF is available here.
Abstract
We review the evidence that patients with Haemophilus influenzae associated Guillain Barré Syndrome recover more quickly than those with other causative agents. We also discuss the implications of thrombocytopenia in these patients and the management of hyperthermia in an intensive care unit settin...
|
PMID: 18853594
PDF is available here.
PDF is available here.
Abstract
A single dose of 50 microg/kg of anti-D raised platelet count as efficiently as IVIG in newly diagnosed cases of ITP in Korean children. Although 50 microg/kg of anti-D had a greater effect on the hemoglobin concentration than IVIG, the adverse effects were found to be acceptable, and no serious eve...
|
PMID: 18799936
PDF is available here.
PDF is available here.
Zhongguo shi yan xue ye xue za zhi / Zhongguo bing li sheng li xue hui = Journal of experimental hematology / Chinese Association of Pathophysiology (16)4 2008
Abstract
CD4(+)CD25(+) regulatory T cells are thought to be a subgroup of cells which have the function of immune suppression. 5 to 10 percentage of peripheral CD4(+) T cells and 1% - 2% of peripheral mononuclear cells are CD4(+)CD25(+) regulatory T cells in mouse or healthy human. They can suppress immune r...
|
PMID: 18718098
PDF is available here.
PDF is available here.
Abstract
Thrombosis of the portal venous system is a well-recognized and potentially lethal complication after open or laparoscopic splenectomy. A 7-year-old girl with idiopathic thrombocytopenic purpura developed a portal vein thrombosis after open splenectomy. The portal vein thrombosis was diagnosed by co...
|
PMID: 18675623
PDF is available here.
PDF is available here.
Abstract
Immune thrombocytopenic purpura (ITP) is the commonest cause of sudden onset thrombocytopenia in a healthy child. The condition is frequently preceded by a viral infection. The hematological parameters are essentially normal except a low platelet count. Bone marrow examination is not routinely indic...
|
PMID: 18716743
PDF is available here.
PDF is available here.
Haematologica (93)7 2008
Abstract
Ugeskrift for laeger (170)24 2008
Abstract
Today several monoclonal antibodies, including the anti-CD20 antibody (rituximab), the anti-CD52 antibody (alemtuzumab) and the anti-CD33 antibody (gemtuzumab ozogamacin) are all integrated in the therapeutic armamentarium of patients with malignant lymphoma, chronic lymphocytic leukaemia and acute...
|
PMID: 18565291
PDF is available here.
PDF is available here.
Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive (16)2 2008
Abstract
We report a case of an immunocompetent child with clinical and serological evidence of Bartonella henselae infection presenting with purpura and cervical lymphoadenopathy and treated with intravenous immunoglobulin. The patient obtained a rapid and persistent increase in platelet count and a complet...
|
PMID: 18622151
PDF is available here.
PDF is available here.
Pathology International (58)6 2008
Abstract
A 64-year-old Japanese woman suffering from idiopathic thrombocytopenic purpura was treated with prednisolone. During the course of steroid withdrawal she developed parotid gland enlargement and cervical lymph node swelling with multiple dome-shaped red papules on her trunk and upper limbs. On admis...
|
PMID: 18477219
PDF is available here.
PDF is available here.
Leukemia Research (32)5 2008
Abstract
We report a case in which these disorders were associated with an occult large granular lymphocyte leukemia. The peripheral blood cytopenias improved after glucocorticoids and intravenous immunoglobulin were administered, and response was maintained with cyclosporine. Large granular lymphocyte leuke...
|
PMID: 17915315
PDF is available here.
PDF is available here.
Abstract
Pediatrics (121)3 2008
Abstract
A total of 1,036,689 children received 1,107,814 measles-mumps-rubella vaccinations; there were 259 confirmed patients with immune thrombocytopenia purpura. Because only 5 exposed cases occurred after age 2, analyses were limited to children aged 12 to 23 months. Exposed patients aged 12 to 23 month...
|
PMID: 18310189
PDF is available here.
PDF is available here.
Pediatrics (121)3 2008
Abstract
Abstract
The Lancet (371)9610 2008
Abstract
Transfusion (48)2 2008
Abstract
BACKGROUND: During the past three decades, HLA matching for platelet (PLT) transfusion of refractory thrombocytopenic patients has been based on serologic cross-reactivity between HLA-A and HLA-B antigens. Although many blood banks are using this matching strategy, the general experience is that suc...
|
PMID: 18005328
PDF is available here.
PDF is available here.
Endokrynologia, diabetologia i choroby przemiany materii wieku rozwojowego : organ Polskiego Towarzystwa Endokrynologow Dzieciecych (14)2 2008
Abstract
We describe here a young girl who developed severe thrombocytopenia following Varicella infection. She was previously diagnosed with diabetes. In addition she demonstrated anti-nuclear factor positivity. Immune thrombocytopenic purpura induced by varicella is rare in children with diabetes.
|
PMID: 18721501
PDF is available here.
PDF is available here.
Abstract
Splenectomy has 50% to 70% long-term efficacy for immune thrombocytopenic purpura (ITP). In some patients, relapse is due to the presence of residual accessory splenic tissue.
|
PMID: 18765061
PDF is available here.
PDF is available here.
Epidemiology and Infection (136)1 2008
Abstract
We sought to identify both outcomes and current management strategies using prospective, national surveillance of HUS and TTP, from 2003 to 2005 inclusive. We also investigated the links between these disorders and factors implicated in the aetiology of HUS and TTP including infections, chemotherapy...
|
PMID: 17335633
PDF is available here.
PDF is available here.
Immunologic Research (42)1-3 2008
Abstract
Our laboratory has combined these techniques with novel selection methods to isolate extraordinarily large arrays of human antibodies that can be used for developing new diagnostic reagents and methods for their use, as well as reagents that may serve as leads for the design of novel therapeutic mol...
|
PMID: 18773308
PDF is available here.
PDF is available here.
Complement activation in vitro by antiplatelet antibodies in chronic immune thrombocytopenic purpura
Abstract
We assessed the ability of various antiplatelet antibodies (APA) to activate and deposit complement proteins and to cause platelet lysis in vitro. Platelet sensitization with rabbit APA, anti-PlA1 antibody (one patient), anti-HLA antibody (two patients) and ITP autoantibodies (four patients) resulte...
|
PMID: 3718872
PDF is available here.
PDF is available here.
Abstract
Acta Paediatrica (96)11 2007
Abstract
The HPA-15 platelet (PLT) group was recently described. Severe neonatal thrombocytopenia due to alloimmunization by HPA-15b has very rarely been observed. A 22-year-old mother, gravida 1/para 1, gave birth to a male infant who presented with a severe thrombocytopenia, the PLT count recorded to be 3...
|
PMID: 17850392
PDF is available here.
PDF is available here.
New England Journal of Medicine (357)18 2007
Abstract
New England Journal of Medicine (357)18 2007
Abstract
Seminars in Hematology (44)4 Suppl 5 2007
Abstract
Thrombopoietin (TPO) is a potent endogenous cytokine and the principal regulator of platelet production. Advances in the understanding of the structure of TPO enabled development of the first generation of thrombopoietic growth factors, recombinant human thrombopoietin (rhTPO) and pegylated human re...
|
PMID: 18096471
PDF is available here.
PDF is available here.
Abstract
Abstract
I large white X Landrace females. Colostrum, containing maternal antibodies incompatible with platelet antigens inherited from the sire, was ingested and absorbed by the piglets. Six piglets were affected and displayed signs of lethargy and depression with petechiation, ecchymosis, and severe bruisi...
|
PMID: 17824332
PDF is available here.
PDF is available here.
Journal of Dermatology (34)7 2007
Abstract
We experienced a 69-year-old male who developed thrombocytopenic purpura due to tosufloxacin tosilate. The diagnosis was made when similar symptoms (petechiae and thrombocytopenia) were induced by inadvertent challenge with tosufloxacin tosilate. In this paper, we report the first case of tosufloxac...
|
PMID: 17584324
PDF is available here.
PDF is available here.
Archives de Pédiatrie (14)6 2007
Abstract
Abstract
QoL was impaired in patients with ITP, especially in the acute patients. The platelet count and the feeling of fear about bleeding had a detrimental impact on QoL....
|
PMID: 17419740
PDF is available here.
PDF is available here.
Abstract
Eighty-five questionnaires were evaluated. Age (median 34 yr) and gender distribution (38% male, 62% female) were similar to other surveys. Median duration of disease was 5.2 yr. Seventy-five percent had platelets <20,000/microL at the time of diagnosis. Twenty-four percent still had <20,000 platele...
|
PMID: 17331128
PDF is available here.
PDF is available here.
Abstract
Abstract
Abstract
A 35-week pregnant 38-year-old woman presented with isolated thrombocytopenia (platelet count 4 x 10(9)/l). Investigations confirmed immune thrombocytopenic purpura, and she received treatment with prednisolone and intravenous immunoglobulins with no increment in the platelet count. At 37 and 38 wee...
|
PMID: 17309547
PDF is available here.
PDF is available here.
Abstract
We report a case of ITP after primary CMV infection in a 3-year-old boy recipient of living-related orthotopic liver transplantation (OLT). The ITP developed 2 years after OLT in this patient who had received tacrolimus as an immunosuppressive agent, with nadir platelet counts of 5000/mm(3) in 2 wee...
|
PMID: 17475612
PDF is available here.
PDF is available here.
Annals of Hematology (86)3 2007
Abstract
We describe 11 patients with severe refractory autoimmune cytopenias treated with the anti-CD20 monoclonal antibody rituximab. Six patients had autoimmune neutropenia (AIN), two had pure red cell aplasia (PRCA), one had AIN and autoimmune haemolytic anaemia, one had AIN and immune thrombocytopaenia...
|
PMID: 17123083
PDF is available here.
PDF is available here.
Abstract
These results suggest that the increase in cytokine expression observed in ITP patients following IVIg or anti-D infusion is not required for their therapeutic effects but may rather represent a side-effect of the treatment....
|
PMID: 17341270
PDF is available here.
PDF is available here.