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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Computer Simulation (0):
Recent article
Computer Simulation
Medical Physics (38)7 2011
Abstract
To create an accurate 6 MV Monte Carlo simulation phase space for the Varian TrueBeam treatment head geometry imported from CAD (computer aided design) without adjusting the input electron phase space parameters.
GEANT4 v4.9.2.p01 was employed to simulate the 6 MV bea...
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PMID: 21858999
PDF is available here.
PDF is available here.
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Abstract
The cancer risk of ionising radiation varies 1000-fold depending on the dose-rate of radiation and exposure conditions. This analysis explains the discrepancy of cancer risk between A-bomb survivors and radium dial painters....
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PMID: 21250929
PDF is available here.
PDF is available here.
Abstract
The quantitative measurements of uncertainties regarding the contents of hazardous trace elements (HTEs) serve as a basis for better assessment of the geochemistry and mineralogical characteristics of coals and their environmental impacts. In this paper, by using bootstrap simulation methodology, a q...
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PMID: 21850830
PDF is available here.
PDF is available here.
Abstract
We consider here polymeric scaffold-based perfusion bioreactors, where an interstitial fluid supplies nutrients and oxygen to the growing biomass. At the same time, the fluid-induced shear acts as a physiologically relevant stimulus for the metabolic activity of cells, provided that the shear stress...
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PMID: 20865436
PDF is available here.
PDF is available here.
Abstract
The control of the mechanical stimuli transmitted to the cells is critical for the design of functional scaffolds for tissue engineering. The objective of this study was to investigate the dynamics of the mechanical stimuli transmitted to the cells during tissue differentiation in an...
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PMID: 20865437
PDF is available here.
PDF is available here.
Systems Biology, IET (5)4 2011
Abstract
The gene expression response of yeast to various types of stresses/perturbations shows a common functional and dynamical pattern for the vast majority of genes, characterised by a quick transient peak (affecting primarily short genes) followed by a return to the pre-stimulus level. K...
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PMID: 21823758
PDF is available here.
PDF is available here.
Abstract
The Hepatitis Delta Virus (HDV) ribozyme, which is well adapted to the environment of the human cell, is an excellent candidate for the future development of gene-inactivation systems. On top of this, a new generation of HDV ribozymes now exists that benefits from the addition of a s...
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PMID: 21793786
PDF is available here.
PDF is available here.
Abstract
We rescored Autodock4-generated poses using mean-field pathway decoupling free energy of binding calculations and evaluated if these calculations improved virtual screening discrimination between bound and non-bound ligands. Two small molecule databases, containing compounds known to either bind or...
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PMID: 21696204
PDF is available here.
PDF is available here.
Abstract
Neuroprostheses based on electrical stimulation could potentially help disabled persons. They are based on neural interface that aim at creating an intimate contact with neural cells. The efficacy of neuroprostheses can be improved by increasing the selectivity of the neural interfac...
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PMID: 21693427
PDF is available here.
PDF is available here.
Abstract
(rac)-1,1'-Binaphthyl-based simple receptors 1 and 2 have been designed, synthesized and studied theoretically. The receptors utilize naphthyridine as the binding motifs for complexation of dicarboxylic acids in CHCl(3). The emission of the BINOL moiety was monitored experimentally to ascertain the s...
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PMID: 21661730
PDF is available here.
PDF is available here.
Biophysics (40)1 2011
Abstract
Over the past 14 years, ubiquitination has emerged as a centrally important mechanism governing the subcellular trafficking of proteins. Ubiquitination, interaction with sorting factors that contain ubiquitin-binding domains, and deubiquitination govern the itineraries of cargo prote...
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PMID: 21332354
PDF is available here.
PDF is available here.
Abstract
This study investigated the effects of aging and localized muscle fatigue on the neural control of upright stance during small postural perturbations. Sixteen young (aged 18-24 years) and 16 older (aged 55-74 years) participants were exposed to small magnitude, anteriorly-directed postural perturbati...
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PMID: 21118760
PDF is available here.
PDF is available here.
Abstract
We leverage general purpose filter design (GPFD) to break both of these critical restrictions, freeing the paralyzed user to make reaching movements to arbitrary target sets with various arrival times and definitive stopping. In silico validation predicts that the new approach, GPFD-RSE, outperforms...
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PMID: 21189232
PDF is available here.
PDF is available here.
Abstract
We apply the Wiener deconvolution technique to deal with noise in input data, and investigate a Tikhonov regularization approach to obtain a stable solution that is robust against variances in the sampling of reaction-time distribution (when number of trials is low). Our method is demonstrated using...
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PMID: 21041149
PDF is available here.
PDF is available here.
Abstract
Understanding how the human speech production system is related to the human auditory system has been a perennial subject of inquiry. To investigate the production-perception link, in this paper, a computational analysis has been performed using the articulatory movement data obtaine...
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PMID: 21682422
PDF is available here.
PDF is available here.
Abstract
We have also applied the ACID (anisotropy of the current-induced density) method in this analysis. The main conclusions are the aromatic character of these compounds, the relationship between aromaticity and planarity and the importance of other factors in this aromaticity....
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PMID: 20811801
PDF is available here.
PDF is available here.
Abstract
Magnesium dimers play important roles in inorganic and organometallic chemistry. This study evaluates the inherent bridging ability of a range of different ligands in magnesium dimers. In the first part, the Cambridge Structural Database is interrogated to establish the frequency of...
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PMID: 20820825
PDF is available here.
PDF is available here.
Abstract
Topological analysis based on DFT calculations regarding proton transfer reaction in salicylideneaniline (SA) was performed to scrutinize possible changes in the intramolecular H-bond, pi-electron delocalization and aromaticity levels of certain fragments. Quantum chemical calculatio...
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PMID: 20820826
PDF is available here.
PDF is available here.
Abstract
Quantum chemical methods have been used to study the conformational and electronic properties of sulfanilamide and derivatives with antibacterial activity. Calculations at B3LYP/6-311++G(3df,2p) level of theory predict the existence of four conformers for sulfanilamide depending on t...
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PMID: 20820828
PDF is available here.
PDF is available here.
Abstract
Our analysis showed that dimeric forms predicted theoretically contribute distinctively to the assignments of experimental results. These structures are defined by the orientation of the acetyl moieties with respect to the plane of indole ring. The dimers are formed by two symmetrical IAA monomers (...
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PMID: 20839020
PDF is available here.
PDF is available here.
Abstract
The formation of α-turns is a possibility to reverse the direction of peptide sequences via five amino acids. In this paper, a systematic conformational analysis was performed to find the possible isolated α-turns with a hydrogen bond between the first and fifth amino acid employin...
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PMID: 20842396
PDF is available here.
PDF is available here.
Abstract
Density functional theoretical calculations have been utilized to investigate the interaction of the amino acid arginine with the (100) surface of anatase and the reproduction of experimentally measured (49)Ti NMR chemical shifts of anatase. Significant binding of arginine through el...
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PMID: 20853182
PDF is available here.
PDF is available here.
Abstract
Enoyl-acyl carrier protein (ACP) reductase (ENR) is an attractive and potential target for developing selective antibacterial agents. Recent studies showed that FabK is the sole isoform of ENR in Streptococcus pneumoniae, and at the same time an X-ray crystallographic study of FabK f...
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PMID: 20862594
PDF is available here.
PDF is available here.
Abstract
Spiking neural P systems are a class of distributed parallel computing devices inspired from the way neurons communicate by means of spikes. In this paper, the problem of looking for small universal computing devices is investigated in the framework of spiking neural P systems. A new...
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PMID: 21712164
PDF is available here.
PDF is available here.
Abstract
We first formulated the simultaneous dual-isotope MPS reconstruction problem as a joint estimation problem. A cross-tracer prior that couples voxel values on both images was then proposed. We developed an iterative algorithm to reconstruct the MPS images that converges to the maximum a posteriori so...
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PMID: 20952334
PDF is available here.
PDF is available here.