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Welcome to the Pubget Medical Subject Headings (MESH) browser. Click on a topic or subtopic below to explore related papers. In the gold box is the most recent paper about the current MESH term, and below are 20 related papers.
Programming Languages (0):
Recent article
Programming Languages
Abstract
We present a Java library to parse the msf files that constitute the output of Proteome Discoverer. The parser is also implemented as a graphical user interface allowing convenient access to the information found in the msf files, and in Rover, a program to analyze and validate quantitative proteomi...
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PMID: 21714566
PDF is available here.
PDF is available here.
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Abstract
We propose here an 'agile' business rule design framework (BRDF) supporting both the design of alerts for the validation of drug prescriptions and the incorporation of the end user into the design process....
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PMID: 20963255
PDF is available here.
PDF is available here.
Abstract
We also implemented an extended version with two competing template cycles. The new insight from our study is that the coupling of reactions in the chemoton ensures that these templates coexist providing an alternative solution to Eigen's paradox. Our technical innovation involves the introduction o...
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PMID: 21818258
PDF is available here.
PDF is available here.
Abstract
Abstract
Graphics technology has extended medical imaging tools to the hands of surgeons and doctors, beyond the radiology suite. However, a common issue in most medical imaging software is the added complexity for non-radiologists. This paper presents the development of a unique software toolset that is high...
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PMID: 21335815
PDF is available here.
PDF is available here.
Medical Physics (37)11 2010
Abstract
Iterative projection reconstruction algorithms are currently the preferred reconstruction method in proton computed tomography (pCT). However, due to inconsistencies in the measured data arising from proton energy straggling and multiple Coulomb scattering, the noise in the reconstructed image increa...
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PMID: 21158301
PDF is available here.
PDF is available here.
Epidemiology (21)6 2010
Abstract
Health Management Technology (31)11 2010
Abstract
Abstract
New Zealand Medical Journal (123)1318 2010
Abstract
The programme of research fits under an overarching theme of "Growing a professional workforce". Seven key areas of activity have been identified: engaging in community and clinical learning environments; improving recruitment and retention; improving phases of transition; assessing professional beh...
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PMID: 20651864
PDF is available here.
PDF is available here.
Abstract
We present a physiological data fusion model for multisensor WHMS called Prognosis. The proposed methodology is based on a fuzzy regular language for the generation of the prognoses of the health conditions of the patient, whereby the current state of the corresponding fuzzy finite-state machine sig...
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PMID: 20123575
PDF is available here.
PDF is available here.
Abstract
Abstract
Exchanging and sharing scientific results are essential for researchers in the field of computational modelling. BioModels.net defines agreed-upon standards for model curation. A fundamental one, MIRIAM (Minimum Information Requested in the Annotation of Models), standardises the ann...
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PMID: 19939940
PDF is available here.
PDF is available here.
Abstract
We have developed the BASIS system for the simulation and storage of stochastic SBML models together with associated simulation results. This system is exposed as a set of web services to allow users to incorporate its simulation tools into their workflows. Parameter inference for stochastic models...
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PMID: 20056731
PDF is available here.
PDF is available here.
Abstract
We provide a brief description of the tool DiVinE adapted for automatized analysis of biological systems dynamics. The tool employs high-performance computing techniques to enable analysis of large models....
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PMID: 20478855
PDF is available here.
PDF is available here.
Journal of Proteomics (73)6 2010
Abstract
We focus on the management of LC-MS data, which are typically made available in standard XML-based portable formats. The structures that are currently employed to manage these data can be highly inefficient, especially when dealing with high-throughput profile data. LC-MS datasets are usually access...
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PMID: 20167298
PDF is available here.
PDF is available here.
Methods in Molecular Biology (631)631 2010
Abstract
Genome-wide targets of chromatin-associated factors can be identified by a combination of chromatin-immunoprecipitation and oligonucleotide microarray hybridization. Genome-wide mircoarray data analysis represents a major challenge for the experimental biologist. This chapter introduces ChIPR, a pac...
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PMID: 20204875
PDF is available here.
PDF is available here.
Genetic Epidemiology (34)2 2010
Abstract
We describe methods and programs for simulating the genotypes of individuals in a pedigree at large numbers of linked loci when the alleles of the founders are under linkage disequilibrium. Both simulation and estimation of linkage disequilibrium models are shown to be feasible on a genome wide scal...
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PMID: 19582786
PDF is available here.
PDF is available here.
Genetic Epidemiology (34)2 2010
Abstract
We describe methods and programs for simulating the genotypes of individuals in a pedigree at large numbers of linked loci when the alleles of the founders are under linkage disequilibrium. Both simulation and estimation of linkage disequilibrium models are shown to be feasible on a genome wide scal...
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PMID: 19582786
PDF is available here.
PDF is available here.
Genetic Epidemiology (34)2 2010
Abstract
We describe methods and programs for simulating the genotypes of individuals in a pedigree at large numbers of linked loci when the alleles of the founders are under linkage disequilibrium. Both simulation and estimation of linkage disequilibrium models are shown to be feasible on a genome wide scal...
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PMID: 19582786
PDF is available here.
PDF is available here.
Genetic Epidemiology (34)2 2010
Abstract
We describe methods and programs for simulating the genotypes of individuals in a pedigree at large numbers of linked loci when the alleles of the founders are under linkage disequilibrium. Both simulation and estimation of linkage disequilibrium models are shown to be feasible on a genome wide scal...
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PMID: 19582786
PDF is available here.
PDF is available here.
Genetic Epidemiology (34)2 2010
Abstract
We describe methods and programs for simulating the genotypes of individuals in a pedigree at large numbers of linked loci when the alleles of the founders are under linkage disequilibrium. Both simulation and estimation of linkage disequilibrium models are shown to be feasible on a genome wide scal...
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PMID: 19582786
PDF is available here.
PDF is available here.
Genetic Epidemiology (34)2 2010
Abstract
We describe methods and programs for simulating the genotypes of individuals in a pedigree at large numbers of linked loci when the alleles of the founders are under linkage disequilibrium. Both simulation and estimation of linkage disequilibrium models are shown to be feasible on a genome wide scal...
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PMID: 19582786
PDF is available here.
PDF is available here.
Genetic Epidemiology (34)2 2010
Abstract
We describe methods and programs for simulating the genotypes of individuals in a pedigree at large numbers of linked loci when the alleles of the founders are under linkage disequilibrium. Both simulation and estimation of linkage disequilibrium models are shown to be feasible on a genome wide scal...
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PMID: 19582786
PDF is available here.
PDF is available here.
Genetic Epidemiology (34)2 2010
Abstract
We describe methods and programs for simulating the genotypes of individuals in a pedigree at large numbers of linked loci when the alleles of the founders are under linkage disequilibrium. Both simulation and estimation of linkage disequilibrium models are shown to be feasible on a genome wide scal...
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PMID: 19582786
PDF is available here.
PDF is available here.
Genetic Epidemiology (34)2 2010
Abstract
We describe methods and programs for simulating the genotypes of individuals in a pedigree at large numbers of linked loci when the alleles of the founders are under linkage disequilibrium. Both simulation and estimation of linkage disequilibrium models are shown to be feasible on a genome wide scal...
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PMID: 19582786
PDF is available here.
PDF is available here.
Genetic Epidemiology (34)2 2010
Abstract
We describe methods and programs for simulating the genotypes of individuals in a pedigree at large numbers of linked loci when the alleles of the founders are under linkage disequilibrium. Both simulation and estimation of linkage disequilibrium models are shown to be feasible on a genome wide scal...
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PMID: 19582786
PDF is available here.
PDF is available here.
Abstract
Dry-lab experimentation is being increasingly used to complement wet-lab experimentation. However, conducting dry-lab experiments is a challenging endeavor that requires the combination of diverse techniques. JAMES II, a plug-in-based open source modeling and simulation framework, fa...
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PMID: 20118105
PDF is available here.
PDF is available here.
Abstract
The Physiome Project is an effort to understand living creatures using "analysis by synthesis" strategy, i.e., by reproducing their behaviors. In order to achieve its goal, sharing developed models between different computer languages and application programs to incorporate into integrated models is...
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PMID: 20217321
PDF is available here.
PDF is available here.
Abstract
A nationwide implementation of a full-scale SIP based on HL7 v3 would include adopting and translating appropriate international coding systems and nomenclatures, and developing implementation guidelines facilitating the migration from national standards to international ones. Our pilot study showed...
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PMID: 19936441
PDF is available here.
PDF is available here.
Abstract
Three main architectural models for system integration are analyzed: the point to point interface, the messages server and the mediator models. Point to point interface and messages server models are completely supported by traditional HL7 version 2 and version 3 messaging. The HL7 v3 standard speci...
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PMID: 20213040
PDF is available here.
PDF is available here.
Abstract
We searched for alternative approaches. To this end, we evaluated scanner generators for various programming languages with respect to their potential of standalone, small and fast applications that can easily delivered on any modern and many ancient operating system. We developed sample application...
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PMID: 20375454
PDF is available here.
PDF is available here.
Abstract
Data management in the life sciences has evolved from simple storage of data to complex information systems providing additional functionalities like analysis and visualization capabilities, demanding the integration of statistical tools. In many cases the used statistical tools are hard-coded withi...
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PMID: 20410555
PDF is available here.
PDF is available here.
Abstract
We present EHRflex, a generic system based on archetypes. It empowers the clinician and allows him to manage his own EHR system in a simple and generic way, assuring that the user works with underlying standardized data structures. These can be exchanged with other people and systems when needed. EH...
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PMID: 20543331
PDF is available here.
PDF is available here.
Abstract
Sharing information and knowledge among heterogeneous health information systems requires semantic interoperability. Most integration projects address semantic interoperability by implementing HL7 version 3 standard interfaces. However, it is challenging to achieve computable semantic interoperabili...
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PMID: 20543317
PDF is available here.
PDF is available here.
Abstract
We describe a proposal and a pilot implementation of a semantic interoperability platform (SIP) interconnecting current EHR-Ss by using HL7 v3 messages and concepts mappings on most widely used classification systems. The increasing number of classification systems and nomenclatures requires designi...
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PMID: 20543319
PDF is available here.
PDF is available here.
Abstract
In considering a 'history' of Health Informatics it is important to be aware that the discipline encompasses a wide array of activities, products, research and theories. Health Informatics is as much a result of evolution as planned philosophy, having its roots in the histories of information techno...
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PMID: 20407147
PDF is available here.
PDF is available here.
Abstract
The Bioconductor project is an "open source and open development software project for the analysis and comprehension of genomic data" (1), primarily based on the R programming language. Infrastructure packages, such as Biobase, are maintained by Bioconductor core developers and serve several key rol...
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PMID: 19957145
PDF is available here.
PDF is available here.
Abstract
BMC Bioinformatics (11) 2010
Abstract
We have developed a software framework, designated here as miRMaid, with the goal of integrating miRNA data resources in a uniform web service interface that can be accessed and queried by researchers and, most importantly, by computers. miRMaid is built around data from miRBase and is designed to f...
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PMID: 20074352
PDF is available here.
PDF is available here.
Abstract
The mean difference between PAL(cell) and PAL(ref) was small (0.014) with narrow limits of agreement (2SD = 0.30). Compared with PAL(ref), the mean difference was also small for PAL(quest1) and PAL(quest2) (0.004 and 0.07, respectively); however, the limits of agreement were wider (PAL(quest1), 2SD...
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PMID: 20118036
PDF is available here.
PDF is available here.
BMC Bioinformatics (11) 2010
Abstract
The new tool allows to compute and visually analyze sequence data for possible co-evolutionary signals. The tool has already been successfully employed in evolutionary studies on HIV1 protease and acetylcholinesterase. The functionality of the tool was defined by users using the tool in real-world r...
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PMID: 20565748
PDF is available here.
PDF is available here.
BMC Bioinformatics (11) 2010
Abstract
Thus mu-CS users can directly manage binary data without worrying about locating and invoking the proper preprocessing tools and chip-specific libraries. Moreover, users of the mu-CS plugin for TM4 can manage Affymetrix binary files without using external tools, such as APT (Affymetrix Power Tools)...
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PMID: 20537149
PDF is available here.
PDF is available here.
Abstract
This format, if widely adopted could promote BSPM interoperability, knowledge sharing and data mining. This work could also be used to provide conceptual solutions and inspire existing formats such as DICOM, SCP-ECG and aECG to support the storage of BSPMs. In summary, this research provides initial...
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PMID: 20470392
PDF is available here.
PDF is available here.
International Conference of the IEEE Engineering in Medicine and Biology Society. Proceedings (2010) 2010
Abstract
Using Web-PACS has become an attractive option that brings access to medical imaging databases from remote hosts. However, the big size of the medical images to be transmitted impacts negatively on the teleradiologist experience by increasing the dead times elapsed between study requ...
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PMID: 21097025
PDF is available here.
PDF is available here.
International Conference of the IEEE Engineering in Medicine and Biology Society. Proceedings (2010) 2010
Abstract
We developed a wireless blood pressure monitoring system which provides a useful tool for users to measure and manage their daily blood pressure values. This system includes an ARM-based blood pressure monitor with a ZigBee wireless transmission module and a PC-based management unit with graphic use...
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PMID: 21095689
PDF is available here.
PDF is available here.
Abstract
We propose a stochastic model of reaction-diffusion systems, in which the diffusion coefficients are function of the local concentration, viscosity and frictional forces. We then describe the software tool Redi (REaction-DIffusion simulator) which we have developed in order to implement this model i...
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PMID: 21098882
PDF is available here.
PDF is available here.
Abstract
We describe a flexible and efficient SAS macro that implements the 2-sample clustered permutation test. We discuss the theory and applications behind this test as well as details of the SAS code....
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PMID: 19321221
PDF is available here.
PDF is available here.
Optics Express (17)13 2009
Abstract
We consider the use of the spatio-temporal Hotelling observer for exoplanet detection....
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PMID: 19550494
PDF is available here.
PDF is available here.
Abstract
We first optimized JPEG2000 code-stream parameters for virtual slide viewing (i.e., fast navigation, zooming, and use of an overview window). Compression using ratios 25:1-30:1 with the irreversible wavelet filter were found to provide the best compromise between file size and image quality. Optimal...
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PMID: 17999112
PDF is available here.
PDF is available here.
Abstract
We show that there is no need to add plug-in components to browsers in order to handle virtual slides on the web. In a heterogeneous healthcare environment, methods using pure HTML and JavaScript to deal with pathologic content are more appropriate than using proprietary technologies supported only...
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PMID: 18584245
PDF is available here.
PDF is available here.
Bioinformatics (25)10 2009
Abstract
SUMMARY: The rise in biological sequence data has led to a proliferation of separate, specialized databases. While there is great value in having many independent annotations, it is critical that there be a way to integrate them in one combined view. The Distributed Annotation System (DAS) was devel...
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PMID: 19297349
PDF is available here.
PDF is available here.
Ecological Applications (19)3 2009
Abstract
Bioinformatics (25)4 2009
Abstract
We developed a C library which provides layout and drawing capabilities for annotation features. It supports several common input and output formats and can easily be integrated into custom C applications. To exemplify the use of AnnotationSketch in other languages, we provide bindings to the script...
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PMID: 19106120
PDF is available here.
PDF is available here.
Abstract
We address the problem of unsupervised feature selection. First, we extend Laplacian linear discriminant analysis (LLDA) to unsupervised cases. Second, we propose a novel algorithm for computing LLDA, which is efficient in the case of high dimensionality and small sample size as in microarray data....
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PMID: 19875859
PDF is available here.
PDF is available here.
Abstract
We present a model version control method, along with a prototype implementation, based on XML patches. We show its application to the EGF/RAS/RAF pathway. CONCLUSION: Our method allows quick and convenient storage of a wide range of model variations and enables a thorough explanation of these varia...
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PMID: 19292901
PDF is available here.
PDF is available here.
Abstract
Here we use a high-level narrative language in designing a computational model of the gp130/JAK/STAT signalling pathway and show that the model reproduces the dynamic behaviour of the pathway derived by biological observation. We then "experiment" on the model by simulation and sensitivity analysis...
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PMID: 19368721
PDF is available here.
PDF is available here.
Abstract
We develop this concept for two purposes. One is to develop a new theory for self-organization and self-assembly of multi-robots systems that can detect and recover from unforeseen errors or attacks. This self-healing and self-regeneration is used to minimize the compromise of overall function for t...
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PMID: 19557691
PDF is available here.
PDF is available here.
Abstract
Mathematical modelling in environmental biotechnology has been a traditionally difficult resource to access for researchers and students without programming expertise. The great degree of flexibility required from model implementation platforms to be suitable for research applications restricts thei...
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PMID: 19182350
PDF is available here.
PDF is available here.
Abstract
We present our CPG-knowledge computerization framework that has been developed and implemented along the lines of knowledge management approaches. This framework adds context, semantics and related meta-information to the CPGs knowledge content using an extended-knowledge component ontology and UMLS...
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PMID: 19745389
PDF is available here.
PDF is available here.