Abstract
The deterministic Acuros XB (AXB) algorithm was recently implemented in the Eclipse treatment planning system. The goal of this study was to compare AXB performance to Monte Carlo (MC) and two standard clinical convolution methods: the anisotropic analytical algorithm (AAA) and the c...
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PMID: 21776802
PDF is available here.
Abstract
We studied the advantages given by a 3D stereoendoscope over a 2D monocular endoscope, first by assessing the variability of stereoacuity in each subject, then in analyzing their overall correct response rate in differentiating between heights of two different images with 2D and 3D vision....
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PMID: 21335748
PDF is available here.
Bram van Ginneken,
Samuel G Armato,
Bartjan de Hoop,
Saskia van Amelsvoort-van de Vorst,
Thomas Duindam,
Meindert Niemeijer,
Keelin Murphy,
Arnold Schilham,
Alessandra Retico,
Maria Evelina Fantacci,
Niccolò Camarlinghi,
Francesco Bagagli,
Ilaria Gori,
Takeshi Hara,
Hiroshi Fujita,
Gianfranco Gargano,
Roberto Bellotti,
Sabina Tangaro,
Lourdes Bolaños,
Francesco De Carlo,
Piergiorgio Cerello,
Sorin Cristian Cheran,
Ernesto Lopez Torres and
Mathias Prokop
Abstract
Numerous publications and commercial systems are available that deal with automatic detection of pulmonary nodules in thoracic computed tomography scans, but a comparative study where many systems are applied to the same data set has not yet been performed. This paper introduces ANODE09 ( http://ano...
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PMID: 20573538
PDF is available here.
Abstract
CBCT simulations defined an average absolute error of 0.94 mm, a standard deviation of 0.90 mm, and a percentage of error less than 2 mm of 86.80%. CONCLUSION: The preliminary results have allowed us to conclude that simulations in orthognathic surgery for skull-maxillofacial deformities using CBCT...
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PMID: 20561464
PDF is available here.
Abstract
Pharmacology decision making requires clinical judgment. The authors created interactive microsimulation applying drug information to varying patients' situations. The theory-based microsimulation requires situational analysis for each scenario. The microsimulation uses an interactive format that al...
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PMID: 20411862
PDF is available here.
Abstract
We studied the networking infrastructure of the hospital and its available image generation devices, we subsequently carried out a series of measurements during the transmissions, which allowed us to analyze the behavior of the system with different network schemes and connection speeds. The results...
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PMID: 20575731
PDF is available here.
Abstract
Depending on the reader's experience, CAD detected between 11 and 21 nodules missed by readers. Human observers found three to 16 lesions missed by the CAD software. CAD used with ES images produced significantly fewer FPs than with non-subtracted images: 1.75 and 2.14 FPs per image, respectively (p...
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PMID: 19936752
PDF is available here.
Abstract
The objective of this study was to develop and validate an automated acquisition system to assess quality of care (QC) measures for cardiovascular diseases. This system combining searching and retrieval algorithms was designed to extract QC measures from electronic discharge notes and to estimate th...
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PMID: 20442141
PDF is available here.
Abstract
Chinese dietary exposure evaluation software was developed successfully. On the rationality, the results from probabilistic model were lower than that from the point estimation (e.g., cucumber: the result of point estimation of acephate was 4.78 microg x kg(-1) x d(-1), while the results of probabil...
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PMID: 20450740
PDF is available here.
Abstract
We present a statistical model and Gibbs sampling approach to generate liability predictions for multifactorial disease for the synthesis stage. We have implemented the approach in a software program. We apply this program to a specimen disease pedigree, and discuss the results produced, comparing i...
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PMID: 19771574
PDF is available here.
Abstract
We present a statistical model and Gibbs sampling approach to generate liability predictions for multifactorial disease for the synthesis stage. We have implemented the approach in a software program. We apply this program to a specimen disease pedigree, and discuss the results produced, comparing i...
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PMID: 19771574
PDF is available here.
Abstract
We present a statistical model and Gibbs sampling approach to generate liability predictions for multifactorial disease for the synthesis stage. We have implemented the approach in a software program. We apply this program to a specimen disease pedigree, and discuss the results produced, comparing i...
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PMID: 19771574
PDF is available here.
Abstract
We present a statistical model and Gibbs sampling approach to generate liability predictions for multifactorial disease for the synthesis stage. We have implemented the approach in a software program. We apply this program to a specimen disease pedigree, and discuss the results produced, comparing i...
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PMID: 19771574
PDF is available here.
Abstract
We present a statistical model and Gibbs sampling approach to generate liability predictions for multifactorial disease for the synthesis stage. We have implemented the approach in a software program. We apply this program to a specimen disease pedigree, and discuss the results produced, comparing i...
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PMID: 19771574
PDF is available here.
Abstract
We present a statistical model and Gibbs sampling approach to generate liability predictions for multifactorial disease for the synthesis stage. We have implemented the approach in a software program. We apply this program to a specimen disease pedigree, and discuss the results produced, comparing i...
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PMID: 19771574
PDF is available here.
Abstract
We present a statistical model and Gibbs sampling approach to generate liability predictions for multifactorial disease for the synthesis stage. We have implemented the approach in a software program. We apply this program to a specimen disease pedigree, and discuss the results produced, comparing i...
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PMID: 19771574
PDF is available here.
Abstract
We present a statistical model and Gibbs sampling approach to generate liability predictions for multifactorial disease for the synthesis stage. We have implemented the approach in a software program. We apply this program to a specimen disease pedigree, and discuss the results produced, comparing i...
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PMID: 19771574
PDF is available here.
Abstract
We present a statistical model and Gibbs sampling approach to generate liability predictions for multifactorial disease for the synthesis stage. We have implemented the approach in a software program. We apply this program to a specimen disease pedigree, and discuss the results produced, comparing i...
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PMID: 19771574
PDF is available here.
Abstract
We highlight the use of the latest version of DESPAIR to decide to what extent additional fine mapping in a candidate region of interest can lead to an increase in power in a previous linkage study sample. We also discuss new features of the program, such as the mean difference test for affected and...
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PMID: 19797908
PDF is available here.
Abstract
For both experimental set-ups analysed in this project (rabbit and sheep bone defects), the objectivity was significantly higher in the GIMP-based evaluation compared to the evaluation according to Mosheiff and Werntz using the Bland-Altman coefficient (rabbit: GIMP: 0.095, Mosheiff: 0.272, Werntz:...
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PMID: 20135589
PDF is available here.
Abstract
Transcribed data from the 29 consultations input into CASC resulted in two diagrams of concept structure and concept space to assess the quality of consultation. The concordance rate between the assessments by CASC and the researchers was 75 percent. ORIGINALITY/VALUE: In this study, a computer-base...
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PMID: 20535907
PDF is available here.
Abstract
The accuracy and flexibility of the Monte Carlo based RapidArc QA system were demonstrated. Good machine performance and accurate dose distribution delivery of RapidArc plans were observed. The sampling used in the TPS optimization algorithm was found to be adequate....
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PMID: 20175472
PDF is available here.
Abstract
The interplay between the motions of the LINAC and the target can result in an error in the delivered dose. This effect increases with plan complexity, and with target magnitude and period. It may average out after many fractions....
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PMID: 20175460
PDF is available here.
Abstract
Colorectal cancer (CRC) screening rates are low despite confirmed benefits. The authors investigated the use of natural language processing (NLP) to identify previous colonoscopy screening in electronic records from a random sample of 200 patients at least 50 years old. The authors developed algorit...
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PMID: 20595304
PDF is available here.
Abstract
Reducing custom software development effort is an important goal in information retrieval (IR). This study evaluated a generalizable approach involving with no custom software or rules development. The study used documents "consistent with cancer" to evaluate system performance in the domains of col...
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PMID: 20595303
PDF is available here.
Abstract
We estimate the level of agreement of the two codes. Nuclear interactions predicted by SHIELD-HIT underestimate the total amount of measured charge. The energy distributions from SHIELD-HIT and GEANT4 show differences exceeding the statistical uncertainties of 2%. Due to a difference of the Bragg cu...
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PMID: 19864697
PDF is available here.
Abstract
The aim of this work was to evaluate the performance of the voxel-based Monte Carlo algorithm implemented in the commercial treatment planning system ONCENTRA MASTERPLAN for a 9 MeV electron beam produced by a linear accelerator Varian Clinac 2100 C/D. In order to realize an experimental verificatio...
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PMID: 19544794
PDF is available here.
Abstract
Several updated Monte Carlo (MC) codes are available to perform calculations of voxel S values for radionuclide targeted therapy. The aim of this work is to analyze the differences in the calculations obtained by different MC codes and their impact on absorbed dose evaluations performed by voxel dos...
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PMID: 19544770
PDF is available here.
Abstract
The precentral cerebellar vein, superior vermian vein, and its tributary, the supraculminate vein, were depicted in 52 (52%) patients. The internal occipital vein was delineated on 99 (49.5%) sides and joined the basal vein and vein of Galen in 39 (39.4%) and 60 (60.6%) hemispheres, respectively. Co...
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PMID: 19404105
PDF is available here.
Abstract
Phantom-based accuracy measurements yielded a mean target point deviation of 0.7 mm. Between February 2007 and April 2008, 27 patients were diagnostically biopsied. Lesion volumes ranged from 0.2 to 117.6 cm3, trajectory length ranged from 25.3 to 64.1 mm, and the diagnostic yield was 93%. CONCLUSIO...
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PMID: 19404116
PDF is available here.
Abstract
We have simulated several cranial base procedures including approaches via the floor of the middle fossa and the lateral petrous bone. The virtual model suitably illustrated the core facts of anatomic spatial relationships while simulating different stages of bone drilling along a variety of surgica...
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PMID: 19404102
PDF is available here.
Abstract
We have found that to reach statistical significance it is generally necessary to trace about 100 neurons in each treatment group. Posttracing data analysis requires importing each text file into a statistics program. Analysis of distinct parameters, such as effects of a treatment on axonal versus d...
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PMID: 18937344
PDF is available here.
Abstract
Recently, Stilgoe, et al., [Opt. Express 16, 15039 (2008)] reported calculations of the force on an optically trapped sphere performed using the "optical tweezers toolbox". This software suffers from numerical inaccuracies that lead to qualitative errors in the state diagram for stable trapping, par...
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PMID: 19219169
PDF is available here.
Abstract
The software-assisted scan simulation was a fast and simple procedure that allowed the selection of optimal computed tomographic parameters in >80% of patients. The procedure may be a useful adjunct to avoid unwanted synchronicity of gantry rotation and heart cycle and optimize temporal resolution i...
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PMID: 19124110
PDF is available here.
Abstract
Human factors (HF) studies are increasingly important as technology infuses into clinical settings. No nursing research reviews exist in this area. The authors conducted a systematic review on designs of clinical technology, 34 articles with 50 studies met inclusion criteria. Findings were classified...
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PMID: 19707093
PDF is available here.
Abstract
Careful selection of quality criteria and the usage of automated process tools lead to a lightweight quality refinement process suitable for scientific research groups that can be applied to ensure a successful transfer of technical software prototypes into clinical research workflows....
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PMID: 19499144
PDF is available here.
Abstract
The PC-based detection and analysis of PQRST points showed a high level of agreement with the CSE database reference values....
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PMID: 19143742
PDF is available here.
Abstract
The use of modern software tools and processes can make a significant contribution to developing reliable software for medical devices. These techniques can help bring products to market more rapidly and cost-effectively because the production of compliance documentation is automated and ensures tha...
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PMID: 19626951
PDF is available here.
Abstract
The automatic landmark identification system was clinically acceptable (p > 0.05 comparing with 2-mm error range) for five landmarks. CONCLUSION: The automatic landmark identification is accurate for only some landmarks. Additional studies may be necessary to improve this method....
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PMID: 20108870
PDF is available here.
Abstract
We tested the performance of our covariance method in measuring thrashing rates of worms using mutations that affect motility and found that it accurately substituted for laborious, manual measurements over a wide range of thrashing rates. The algorithm used also enabled us to determine a dose-depen...
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PMID: 19619274
PDF is available here.
Abstract
Our novel strategy was extensively evaluated using the leave-one-out cross validation strategy on fragments of variable length (800 bp - 50 Kbp) from 373 completely sequenced genomes. TACOA is able to classify genomic fragments of length 800 bp and 1 Kbp with high accuracy until rank class. For long...
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PMID: 19210774
PDF is available here.
Abstract
Using THR Simulator, the users can incorporate many parameters together for radiograph synthesis. These parameters include thickness, film size, tube distance, film distance, anteversion, abduction, upper wear, medial wear, and posterior wear. These parameters are adequate for any radiographic measu...
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PMID: 19149874
PDF is available here.
Abstract
The success of the molecular-replacement method for solving protein structures from experimental diffraction data depends on the availability of a suitable search model. Typically, this is derived from a previously solved structure, sometimes by homology modelling. Very recently, Baker, Read and cow...
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PMID: 19018106
PDF is available here.
Abstract
From 363 terms extracted, 304 (84%) were found and 59 (16%) were not found in RadLex. Report indexing showed a mean of 16.2 encoded items per report and 3.2 Finding per report. Term categories most frequently encoded were Modifier (1,030 of 3,244, 31.8%), Anatomic Location (813, 25.1%), Relationship...
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PMID: 17661140
PDF is available here.
Abstract
Software application frameworks provide a modular and reusable context for the development of custom applications, e.g. in the domain of medical image processing and computer assisted surgery (CAS). The utilization of an appropriate software framework can strongly reduce time and costs for software...
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PMID: 18575913
PDF is available here.
Abstract
The performance of the CAD software indicated that the sensitivity in detecting lung nodules was 71.4%, with 0.95 false-positive results per case. When radiologists used the CAD software, the average sensitivity improved from 39.5% to 81.0%, with an increase in the average number of false-positive r...
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PMID: 19000867
PDF is available here.
Abstract
We describe a fully automated method for hippocampal segmentation. The method uses SPM5 (http://www.fil.ion.ucl.ac.uk/spm/) software to segment the brain into grey/white matter, and spatially normalize the images to standard space. Grey matter pixels within a predefined hippocampal region in standar...
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PMID: 17979118
PDF is available here.
Abstract
MobilDent is a feasible application for oral health assessment fieldwork, and the oral health assessment database may prove a valuable source for care planning, educational and research purposes. Further development of the MobilDent system will include wireless connectivity with download-on-demand t...
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PMID: 18833206
PDF is available here.
Abstract
We present a framework for how full sensitivity mapping can be done in the most efficient way, via spaced seeds. Using the framework, we have developed software called ZOOM, which is able to map the Illumina/Solexa reads of 15x coverage of a human genome to the reference human genome in one CPU-day,...
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PMID: 18684737
PDF is available here.
Abstract
The laparoscopic smoothness metric in the hybrid simulator demonstrated construct validity by effectively differentiating between experienced and novice urology residents using validated MISTELS tasks. The outcome suggests that the hybrid simulator smoothness metric is a valuable asset in residency...
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PMID: 18710760
PDF is available here.
Abstract
In recent years there has been a great effort to convert the existing Air Traffic Control system into a novel system known as Free Flight. Free Flight is based on the concept that increasing international airspace capacity will grant more freedom to individual pilots during the enroute flight phase,...
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PMID: 18991361
PDF is available here.
Abstract
Classification of blood cell types can be time consuming and susceptible to error due to the different morphological features of the cells. This paper presents a blood cell identification system that simulates a human visual inspection and identification of the three blood cell types. The proposed s...
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PMID: 18991367
PDF is available here.
Abstract
We present an approach to compare simulation results between several SBML capable simulators and provide a website for the community to share simulation results. AVAILABILITY: The website with simulation results and additional material can be found under: http://sys-bio.org/sbwWiki/compare. The soft...
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PMID: 18579569
PDF is available here.
Abstract
We demonstrate here that, when proper measures are taken to handle the various sources of temporal error, accuracy can be achieved at the 1 ms time-scale that is relevant for the alignment of behavioral and neural events....
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PMID: 18606188
PDF is available here.
Abstract
With more and more ribonucleic acid (RNA) secondary structures accumulated, the need for comparing different RNA secondary structures often arises in function prediction and evolutionary analysis. Numerous efficient algorithms were developed for comparing different RNA secondary structures, but chal...
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PMID: 18538347
PDF is available here.
Abstract
We present the results of our validation of the Monte Carlo model of the double scattering system used at our Proton Therapy Center in Houston. In this study, we compared Monte Carlo simulated depth doses and lateral profiles to measured data for a magnitude of beam parameters. We varied simulated p...
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PMID: 18670050
PDF is available here.
Abstract
In order to deal with this problem, we propose the use of patterns, that is, high-level query templates that capture recurring biological questions and can be automatically translated into temporal logic. The applicability of the developed set of patterns has been investigated by the analysis of an...
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PMID: 18689830
PDF is available here.