Abstract
We analyzed self-reported computer use, demographic variables, psychosocial variables, and health and well-being variables collected from 460 ethnically diverse, community-dwelling elders to investigate the relationship computer use has with demographics, well-being, and other key psychosocial varia...
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PMID: 22046718
PDF is available here.
Abstract
The objective of this research is to determine the best location to place a conventional mobile computer supported by a commercially available mount in a light truck cab.
U.S. and Canadian electric utility companies are in the process of integrating mobile computers i...
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PMID: 22046721
PDF is available here.
Abstract
In response to concern about lengthy waiting times for cancer treatment in the UK, the Department of Health introduced 'the colorectal cancer target referral scheme' to improve the referral process for suspected cancer. A user-centred web-based intranet software was developed reflect...
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PMID: 21848449
PDF is available here.
Abstract
We have previously created a novel interaction database for oncology prescriptions (OncoRx). In this project, we leverage on 3G networks to further develop this database into an iPhone-specific application for the mobile internet (OncoRx-MI)....
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PMID: 21848450
PDF is available here.
Abstract
To assess the applicability of the Technology Acceptance Model (TAM) constructs in explaining HIV case managers' behavioural intention to use a continuity of care record (CCR) with context-specific links designed to meet their information needs.
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PMID: 21848452
PDF is available here.
Abstract
We investigated the effects of self-controlled practice on learning multiple motor skills. Thirty participants were randomly assigned to self-control or yoked conditions. Participants learned a three-keystroke pattern with three different relative time structures. Those in the self-control group cho...
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PMID: 21957703
PDF is available here.
Abstract
We sought to develop an appropriate method to examine large sets of GPCR ligand information for both screening collection enhancement and hit expansion. To this end, we have implemented a modified version of BDACCS that removes highly correlated descriptors (rBDACCS). To test the hypothesis that a s...
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PMID: 21761904
PDF is available here.
Abstract
We provided healthy subjects and stroke patients with a virtual task during robot-assisted gait training, which allowed modulating cognitive load by adapting the difficulty level of the task. We quantified the cognitive load of stroke patients by using psychophysiological measurements and performanc...
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PMID: 21827971
PDF is available here.
Abstract
We propose to use a robot-tweezer manipulation system to solve the problem of automatic transportation of biological cells, where optical tweezers function as special robot end effectors. Dynamics equation of the cell in optical tweezers is analyzed. A closed-loop controller is designed for transpor...
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PMID: 21764021
PDF is available here.
Abstract
The computation time required for modeling the nonlinear response of an axon to an applied electric field is a significant limitation to optimizing a large number of neural interface design parameters through use of advanced computer algorithms. This paper introduces two methods of p...
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PMID: 21750371
PDF is available here.
Abstract
Abstract Amyotrophic lateral sclerosis (ALS) is a genetically heterogeneous disorder that shows a characteristic dichotomy of familial forms typically displaying Mendelian inheritance patterns, and sporadic ALS showing no or less obvious familial aggregation. While the former is caus...
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PMID: 21702733
PDF is available here.
Abstract
This paper examines the usefulness of psychophysiological measurements in a biocooperative feedback loop that adjusts the difficulty of an upper extremity rehabilitation task. Psychophysiological measurements (heart rate, skin conductance, respiration and skin temperature) were used...
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PMID: 21708507
PDF is available here.
Abstract
In order to harness the computational capacity of dissociated cultured neuronal networks, it is necessary to understand neuronal dynamics and connectivity on a mesoscopic scale. To this end, this paper uncovers dynamic spatiotemporal patterns emerging from electrically stimulated neu...
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PMID: 21622081
PDF is available here.
Abstract
We present results where ten typically-developing toddlers are trained to drive a robot within an obstacle course. We also report a case study with a toddler with spina-bifida who cannot independently walk. Using algorithms based on artificial potential fields to avoid obstacles, we create force fie...
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PMID: 21324787
PDF is available here.
Abstract
We report here the first comprehensive HCV customized biomedical text-mining based online web resource, dragon exploratory system on hepatitis C virus (DESHCV), a biomedical text-mining and relationship exploring knowledge base was developed by exploring literature on HCV. The pre-compiled dictionar...
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PMID: 21194573
PDF is available here.
Abstract
To develop a novel four-dimensional (4D) intensity modulated radiation therapy (IMRT) treatment planning methodology based on dynamic virtual patient models.
The 4D model-based planning (4DMP) is a predictive tracking method which consists of two main steps: (1) predi...
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PMID: 21776801
PDF is available here.
Abstract
We achieved specific bodily conflicts and induced predictable changes in a fundamental aspect of self-consciousness by altering where healthy subjects experienced themselves to be (self-location). Functional magnetic resonance imaging revealed that temporo-parietal junction (TPJ) activity reflected...
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PMID: 21521620
PDF is available here.
Abstract
We tested the use of a slide scanned from a stained specimen ("virtual slide"). All participants (n = 57) received a sample of the following supports: an unstained slide, a stained one and a virtual slide, all of them from a single human ejaculate. The required tests were the proportion of typic...
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PMID: 21464012
PDF is available here.
Abstract
The objective was to update estimates of maximum potential crash reductions in the United States associated with each of four crash avoidance technologies: side view assist, forward collision warning/mitigation, lane departure warning/prevention, and adaptive headlights. Compared with previous estima...
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PMID: 21376861
PDF is available here.
Abstract
This study presents an evaluation of driver performance while text messaging via handheld mobile phones and an in-vehicle texting system. Participants sent and received text messages while driving with an experimenter on a closed-road course, using their personal mobile phones and the vehicle's syste...
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PMID: 21376886
PDF is available here.
Abstract
A novel system for the vascular tree identification and the quantitative estimation of arteriolar venular ratio clinical index in retinal fundus images is presented. The system is composed of a module for automatic vascular tracking, an interactive editing interface to correct errors and set the requ...
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PMID: 20952330
PDF is available here.
Abstract
We used a 40% video compression, and data feature upload requiring 1 min of extra time following a 10 min interactive session. These results indicate that the proposed platform is suitable to monitor patients with PD to facilitate the titration of medications in the late stages of the disease....
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PMID: 21041152
PDF is available here.
Abstract
To develop and validate a fast and accurate method that uses computed tomography (CT) voxel data to estimate absorbed radiation dose at a point of interest (POI) or series of POIs from a kilovoltage (kV) imaging procedure.
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PMID: 21520849
PDF is available here.
Abstract
Physician requests for additional testing on an existing laboratory specimen (add-ons) are resource intensive and generally require a phone call to the laboratory. Verbal orders such as these have been noted to be associated with errors in accuracy. The aim of this study was to compare a novel comput...
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PMID: 21303296
PDF is available here.
Abstract
Human-robot control interfaces have received increased attention during the last decades. These interfaces increasingly use signals coming directly from humans since there is a strong necessity for simple and natural control interfaces. In this paper, electromyographic (EMG) signals from the muscles...
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PMID: 20403787
PDF is available here.
Abstract
The initial testing of the new PEM/PET system demonstrated that the new system is capable of producing good quality breast-PET images compared standard methods.
© 2011 The Authors. Journal of Medical Imaging and Radiation Oncology © 2011 The Royal Australian and New Zealand College...
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PMID: 21382190
PDF is available here.
Abstract
We use a method called contrast common pattern classifier (CCPC) to predict chemical-protein binding activity. This approach is strongly associated with the classical emerging patterns techniques known from decision tables. It uses two different types of structural patterns (subgraphs): contrast and...
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PMID: 21431564
PDF is available here.
Abstract
We coupled a differential-equation-based model of antimicrobial kinetics to a Monte Carlo simulation framework, and conducted "in silico" clinical trials to explore the anticipated effects of different antimicrobial dosing regimens on relevant pharmacokinetic parameters (AUC/MIC and time greater tha...
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PMID: 21431580
PDF is available here.
Abstract
A brain machine interface (BMI) design for controlling the navigation of a power wheelchair is proposed. Real-time experiments with four able bodied subjects are carried out using the BMI-controlled wheelchair. The BMI is based on only two electrodes and operated by motor imagery of four states. A re...
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PMID: 21431597
PDF is available here.
Abstract
Information and communication technologies progress rapidly and many novel applications have been developed in many domains of human life. In recent years, the demand for healthcare services has been growing because of the increase in the elderly population. Consequently, a number of healthcare insti...
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PMID: 21431601
PDF is available here.
Abstract
The broad range of Computer Assisted Surgery (CAS) represents the integration of computer technology in surgical procedures for presurgical planning, guiding or manipulation. Surgical robots and surgical endoscopic navigation are the most challenging applications to urology. A surgical robot is defin...
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PMID: 21452161
PDF is available here.
Abstract
We strive to promote software improvements; in our case, the physician discharge letter composition process at the Department of Dermatology, University Hospital Erlangen, Germany....
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PMID: 20091017
PDF is available here.
Abstract
An increase of diabetes prevalence of up to 80% is predicted in sub-Saharan Africa (SSA) by 2025 exceeding the worldwide 55%. Mortality rates of diabetes and HIV/AIDS are similar. Diabetes shares several common factors with HIV/AIDS and multidrug-resistant tuberculosis (MDR-TB). The latter two health...
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PMID: 19936439
PDF is available here.
Abstract
Malaria modeling can inform policy and guide research for malaria elimination and eradication from local implementation to global policy. A research and development agenda for malaria modeling is proposed, to support operations and to enhance the broader eradication research agenda. Models are envisi...
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PMID: 21283605
PDF is available here.
Abstract
The heightened focus on health information technology deployment, specifically the electronic health record, has magnified the need for the knowledge and skills of informaticians. The clinical informatician is frequently confused with system analyst and project management roles. In this article, the...
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PMID: 21157241
PDF is available here.
Abstract
We developed for the analysis of MEG, EEG, and other electrophysiological data. The software is implemented as a MATLAB toolbox and includes a complete set of consistent and user-friendly high-level functions that allow experimental neuroscientists to analyze experimental data. It includes algorithm...
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PMID: 21253357
PDF is available here.
Abstract
We have developed an online resource, HelmCoP (Helminth Control and Prevention), built by integrating functional, structural and comparative genomic data from plant, animal and human helminthes, to enable researchers to develop strategies for drug, vaccine and pesticide prioritization, while also pr...
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PMID: 21760913
PDF is available here.
Abstract
The data collected in this study can only be used to provide insight into the performance on the system since the sample size was limited. The next stage for this project is to test the system with a larger sample size to obtain significant results....
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PMID: 21679457
PDF is available here.
Abstract
Tuberculosis (TB) continues to pose a serious challenge to human health afflicting a large number of people throughout the world. In spite of the availability of drugs for the treatment of TB, the non-compliance to 6-9 months long chemotherapeutic regimens often results in the emergence of multidrug...
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PMID: 21818324
PDF is available here.
Abstract
We present a computational approach for predicting the DFG-out inactive conformation using the DFG-in active structures, and develop related conformational selection protocols for the uses of the predicted DFG-out models in the binding pose prediction and virtual screening of type-II ligands. With t...
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PMID: 21818358
PDF is available here.
Abstract
Heuristic evaluation and user testing can help identify usability problems in the early stages of application development, and improve the construct validity of electronic assessments such as the HEADACHE-CAT. An improved computerized HEADACHE-CAT measure can offer headache sufferers an efficient to...
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PMID: 21214341
PDF is available here.
Abstract
We outline the successful creation and implementation of a wrapper class for one robot into the open-source H3DAPI, which integrates the software commands most commonly used by all robots....
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PMID: 21847086
PDF is available here.
Abstract
This study evaluated a newly developed online color training system. The system incorporated basic color training, shade guide matching, and clinical shade selection simulation exercises. Thirty-seven dental students went through baseline Vita-Vita testing with VITA Classical shade guides and then pr...
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PMID: 21479280
PDF is available here.
Abstract
The problems pertaining to the safety of information and communication technologies used in the spheres of education and leisure activities of children and adolescents are discussed. The relevant risk factors are identified. Results of physiological and hygienic studies for substantiating regulations...
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PMID: 21786601
PDF is available here.
Abstract
Our research shows that consistent multisensory input can enhance the visual perception of self-motion in some situations. However, it is clear that multisensory stimulation does not have to be consistent (i.e., ecological) to generate compelling vection in depth....
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PMID: 21650090
PDF is available here.
Abstract
We present several examples of successful applications of both approaches for virtual screening to illustrate their utility. We suggest that the expert use of both QSAR and pharmacophore models, either independently or in combination, enables users to achieve targeted libraries enriched with experim...
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PMID: 20981521
PDF is available here.
Zhengwei Peng,
Bo Yang,
Sarathy Mattaparti,
Thom Shulok,
Thomas Thacher,
James Kong,
Jaroslav Kostrowicki,
Qiyue Hu,
James Na,
Joe Zhongxiang Zhou,
David Klatte,
Bo Chao,
Shogo Ito,
John Clark,
Nunzio Sciammetta,
Bob Coner,
Chris Waller and
Atsuo Kuki
Abstract
We describe the three-tier enterprise software architecture, key data structures that enable a wide variety of design scenarios and workflows, major technical challenges encountered and solved, and lessons learned during its development and deployment throughout its production cycles. In addition, P...
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PMID: 20981530
PDF is available here.
Abstract
We give a short introduction to PGVL Hub, the core workflow it supports, and the rich design capabilities it provides. By re-creating two legacy targeted libraries against the human checkpoint kinase 1 (Chk1) as a showcase, we illustrate how PGVL Hub could be used to help library designers carry out...
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PMID: 20981531
PDF is available here.