Tripodal molecules consisting of a tetrasubstituted adamantane with three phenylacetylene legs and a reversibly photoswitching apex were designed as "single molecular tips" for both chemical and topographical characterization of the substrate surface. By covalent attachment onto gold-coated AFM tips... | PMID: 20589278

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A one-step homogeneous colorimetric immunoassay format coupled with zeta potential measurements for determination of specific diabetic biomarker glycated hemoglobin (HbA1c) using functionalised gold nanoparticles as bioprobes is reported. The assay exhibited an excellent sensitivity based on absorba... | PMID: 20571696

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The synthesis and growth mechanism of well-defined nanostructures are still challenging. In this study, gold microplates with starlike, shieldlike, and other polygonal shapes are successfully achieved in high yields on the basis of the polyol process. Structural studies demonstrate that these newly... | PMID: 20665630

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PMID: 20665752

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This paper begins with an extensive review of the formation of gas bubbles, with a particular focus on the dynamics of triple lines, in a pure liquid and progresses into an experimental study of bubble formation on a micrometer-sized nozzle immersed in a quiescent pool of aqueous gold nanofluid. Unl... | PMID: 20591394

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The targeted cell line Panc-1 had a viability of 46% +/- 12%, whereas the Cama-1 cell had a viability of 92% +/- 2% after RF field exposure (P < .008). Transmission electron microscopy showed gold nanoparticle uptake in Panc-1 cells but negligible uptake by Cama-1 cells. Nontargeted cells do not int... | PMID: 20541785

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Collectively, fluorescent confocal microscopy, transmission electron microscopy, mass spectrometry, and flow cytometry revealed substantial penetration of the AuNP-DNA conjugates into the inner core of the islets and within islet cells. No change in cellular viability occurred and the insulin stimul... | PMID: 20633730

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We studied the reaction between NO, NO donors, and commonly used HNO donors, with Co(II)(P) and Co(III)(P). Second, we covalently attached Co(II)(P) to gold electrodes and characterized its redox and structural properties by electrochemical techniques as well as scanning tunneling microscopy, X-ray... | PMID: 20604525

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PMID: 20564259

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The additional absorption of radiation and the subsequent increase in secondary electrons, attributable to the presence of gold in Au@DTDTPA:Gd, does not lead to radiosensitisation. However, this chelating agent exhibits a chemotherapeutic action which warrants further investigation. When compared t... | PMID: 20586540

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To study crystal growth rates of amorphous griseofulvin (GSF) below its glass transition temperature (T (g)) and the effect of surface crystallization on the overall crystallization kinetics of amorphous GSF. Amorphous GSF was generated by melt quenching. Surface and... | PMID: 20414704

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To characterize and evaluate chitosan film containing PLGA nanoparticles (NPs) as a platform for localized dual-drug release. Fluorescent Paclitaxel (FPTX), a hydrophobic drug, was incorporated into PLGA NPs. FPTX-loaded PLGA NPs and Carboxyfluorescein (CF), a hydroph... | PMID: 20521086

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Thermoresponsive nanohydrogels cross-linked by gold nanoparticles (AuNPs) were prepared by 1,3-dipolar cycloaddition reactions and in situ reversible addition-fragmentation chain-transfer (RAFT) polymerization. In order to synthesize thermoresponsive nanohydrogels, AuNPs decorated wi... | PMID: 20669920

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Optimisation of colloidal properties allows Surface Enhanced Raman Scattering (SERS) to be recorded from a range of analytes at 1546 nm, demonstrating the potential of SERS for use in a wavelength region of particular value for applications such as homeland security. | PMID: 20485767

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Our results show that the dipstick based bioassay is sufficiently sensitive to allow for detection of Paraoxon over the concentration range of 500 nM to approximately 1 mM. Detection can be made by eye or using a digital camera and image analysis, making the assay suitable for remote analysis.... | PMID: 20593080

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A new fluoro-chromogenic chemosensor based on BODIPY-functionalized gold nanoparticles 1 is prepared. Addition of Cu(2+) ions to aqueous solutions of 1 gave an instantaneous color change along with a blue-shift of the absorption band and quenching of the emission spectrum at room temperature. The ch... | PMID: 20574565

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A new strategy was described for amplifying the response of the antigen-antibody sensing processes by functionalizing SiO(2) nanoparticles labeled secondary antibodies based on a sandwich immunoassay in this work. At first, the multi-walled carbon nanotubes (CNTs) were individually dispersed in the... | PMID: 20523934

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A stable and controllable Prussian blue (PB) layer electrodeposited on self-assembled monolayers (SAMs) of thioctic acid amide (T-NH(2)) on gold electrode was prepared. The PB, combining with biocompatible matrix chitosan, was used for the highly efficient immobilization of glucose oxidase (GOD) for... | PMID: 20517545

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Preparation of a high-concentration Au nanoring (NR) water solution and its applications to the enhancement of image contrast in optical coherence tomography (OCT) and the generation of the photothermal effect in a bio-sample through localized surface plasmon (LSP) resonance are demonstrated. Au NRs... | PMID: 20601768

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We used multiple endpoints to characterize the cellular cytotoxic response of a range of cell lines to 1.9 nm gold particles and measured dose modifying effects following transient exposure at low concentrations. Gold nanoparticles caused significant levels of cell type specific cytotoxicity, apopto... | PMID: 20601762

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Chiral ionic liquid monolayer-stabilized gold nanoparticles were synthesized in a two-phase liquid-liquid system and found to self-assemble into ringlike structures at the air/water interface. Control experiments with long-chain ILs revealed that the molecular structure of the CIL significantly affe... | PMID: 20499920

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Unique, porous gold nanobelts consisting of self-organized nanoparticles were synthesized in a high yield by morphology-preserved transformation from metal-surfactant complex precursor nanobelts formed by a bolaform surfactant dodecane-1,12-bis(trimethylammonium bromide) (N-C(12)-NBr(2)) and HAuCl(4... | PMID: 20503996

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We have developed a simple, colorimetric and label-free gold nanoparticle (Au NP)-based probe for the detection of Pb(2+) ions in aqueous solution, operating on the principle that Pb(2+) ions change the ligand shell of thiosulfate (S(2)O(3)(2-))-passivated Au NPs. Au NPs reacted with S(2)O(3)(2-) io... | PMID: 20602929

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In this study, a new, sensitive, and rapid assay was developed to quantitatively measure the proteolytic enzyme activity using the surface-enhanced Raman scattering (SERS) probe. Two different shapes of gold nanoparticles, gold nanosphere and nanorod particles were produced. SERS label, comprising s... | PMID: 20602947

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