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Free Radicals (2):
Recent article
Free Radicals
Abstract
We also describe our experimental set-up for studying peroxynitrite-mediated degradation of hyaluronan, a system, which may be suitable for testing prospective pharmacological substances....
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PMID: 21952432
PDF is available here.
PDF is available here.
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Abstract
These results are consistent with a C3 α-hydroxyalkyl radical in which the p-orbital harboring the unpaired electron spin at C3 is periplanar with the C-H bonds at both C2 and C4....
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PMID: 21513273
PDF is available here.
PDF is available here.
Abstract
Disproportionation of dipyrrolylquinoxaline radical anions occurs via hydrogen atom transfer from the pyrrole moiety to the quinoxaline moiety to produce monodeprotonated dipyrrolylquinoxaline anions and monohydrodipyrrolylquinoxaline anions. In contrast, simple quinoxaline radical anions without pyr...
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PMID: 21510700
PDF is available here.
PDF is available here.
médecine/sciences (27)4 2011
Abstract
Oxidative stress is defined as an imbalance between the production of reactive oxygen species (ROS) and the antioxidant capacity of the cell. For long, ROS have been considered as harmful by-products of the normal aerobic metabolism process of the mitochondria, implicated in a large variety of diseas...
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PMID: 21524406
PDF is available here.
PDF is available here.
Abstract
A comparative H2O2-luminol- and Fe(II)-induced chemiluminescence analysis of extracts of two strains of marine oil oxidizing bacteria Actinetobacter calcoaceticus cultivated either in the presence or absence of oil was carried out. Effects of these extracts on E. coli MG1655 biosensor (pSoxS-lux) wer...
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PMID: 21950119
PDF is available here.
PDF is available here.
Abstract
Four bis-phenolate complexes [Zn(II)L], [Ni(II)L], [Cu(II)L] and [Co(II)L] (where [H(2)L = 2,2'-[2,2']bipyridinyl-6-yl-bis-4,6-di-tert-butylphenol] have been synthesized. The copper(II) and nickel(II) complexes have been characterized by X-ray diffraction, showing a metal ion within a square planar...
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PMID: 20820605
PDF is available here.
PDF is available here.
Abstract
We also report an updated G2(MP2) proton affinity of tryptophan (PA = 946 kJ mol(-1)) and hydrogen atom affinities of the tryptophan indole ring of relevance to electron-based peptide dissociations....
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PMID: 20830385
PDF is available here.
PDF is available here.
Abstract
Reductive elimination of a bridged chlorine from a diiridium(iii) core, [(dfpbo)(2)Ir(μ-Cl)](2) (dfpbo = 2-(3.5-difluorophenyl)benzoxazolato-N,C(2)), afforded an iridium dimer, [(fpbo)(2)Ir](2)(μ-Cl), showing an 18+δ structure with a bent bridge, which can release metalloradicals spontaneously in...
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PMID: 20820618
PDF is available here.
PDF is available here.
Free Radical Research (44)11 2010
Abstract
An increasing incidence of unresponsiveness to antimonials in Leishmaniasis has led to identification of plant-derived anti-leishmanial compounds like Artemisinin. Since iron-mediated generation of free radicals sustains the anti-malarial activity of Artemisinin, this study investigated whether simi...
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PMID: 20815780
PDF is available here.
PDF is available here.
Abstract
The extent to which deuterium can act as a protecting group to prevent unwanted 1,5-hydrogen atom transfer to aryl and vinyl radical intermediates was examined in the context of the generation of α-aminoalkyl radicals in a pyrrolidine ring. Intra- and intermolecular radical trapping following hydro...
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PMID: 20714669
PDF is available here.
PDF is available here.
Abstract
Free radicals (FRs) and oxidants (Os) have different vital activities in our bodies. Biological redox reactions are the major source for FRs-Os. In normal cases, they are under the control of our body's existing antioxidant (antiO) system. If their amounts exceeds a certain limit, they start to atta...
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PMID: 21105570
PDF is available here.
PDF is available here.
Food and Chemical Toxicology (48)10 2010
Abstract
Ninety female Balb/c mice were used. The animals were allocated to evenly six groups. While the first group was maintained as control, Groups 3, 4, 5, and 6 were administered 750 ppm, 1500 ppm, 3000 ppm, and 6000 ppm of N-acetylcysteine, respectively, for a period of 15 days. After day 15, Groups 2-...
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PMID: 20637250
PDF is available here.
PDF is available here.
Abstract
Chemoenzymatic dynamic kinetic resolution (DKR) of amines involving sulfanyl radical-induced racemization happened to be the very first switchable DKR process allowing the synthesis of either (R)- or (S)-amides, in good yield and high enantiomeric excess, depending on the nature of the enzyme; the d...
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PMID: 20661510
PDF is available here.
PDF is available here.
Abstract
Benzoyl radicals are generated directly from (hetero)aromatic aldehydes upon tetrabutylammonium decatungstate ((n-Bu(4)N)(4)W(10)O(32)), TBADT) photocatalysis under mild conditions. In the presence of alpha,beta-unsaturated esters, ketones and nitriles radical conjugate addition ensues and gives the...
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PMID: 20661511
PDF is available here.
PDF is available here.
Kidney International (78)10 2010
Abstract
Although chemokines, as chemotactic factors, were already known in 70's of the past century, it was only the progress in molecular biology, genetics and immunology which occurred in the past few years that opened the way to discover new molecules, their chemical structure and biological functions. F...
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PMID: 19388544
PDF is available here.
PDF is available here.
Abstract
Three new complexes of the general formula L[RuCl(3)(DMSO)(3)] (1-3), where L = chlorpromazine hydrochloride, trifluoroperazine dihydrochloride or thioridazine hydrochloride, were prepared and characterized by elemental analysis and spectroscopic methods (FT-IR, UV-Vis, (1)H NMR and (13)C NMR). In a...
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PMID: 20684856
PDF is available here.
PDF is available here.
Abstract
We recently developed a technique for free radical and oxidative stress monitoring using the ex vivo electron spin resonance (ESR) spin trapping method in patients with neuroemergency. Blood samples were collected by catheterization of the internal jugular bulb. The alkoxyl radical level was measure...
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PMID: 19812971
PDF is available here.
PDF is available here.
Abstract
Administration of reamberin leads to rapid reduction of the intoxication symptoms, improves general condition, and reduces fever stage duration. The dynamics of inflammatory symptoms is characterized by decreasing duration of hemocolitis in comparison that in patients receiving glucose-salt solution...
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PMID: 21086650
PDF is available here.
PDF is available here.
Abstract
Using periodic DFT calculations, it is concluded that the stable radiation-induced alanine radical most probably is the result of reductive deamination and protonation of the detached amino group, yielding an NH(4)(+) ammonium ion and a negatively charged radical.
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PMID: 20559598
PDF is available here.
PDF is available here.
Abstract
This paper details the study of applicability of microwave initiated synthesized polyacrylamide grafted guar gum (GG-g-PAM) as matrix for controlled release of 5-amino salicylic acid (a drug used for the treatment of ulcerative colitis). In vitro release of this drug from various grades of GG-g-PAM...
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PMID: 20471416
PDF is available here.
PDF is available here.
Abstract
The photophysical and photochemical properties of violanthrone (V1) and two 16,17-R derivatives with R = OC(8)H(17) and OCOC(17)H(35) (V2 and V3, respectively) in solution were examined. The fluorescence quantum yield of V3 is Phi(f) = 0.2, while that of V1 is low (0.01) and V2 even lower. A radical...
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PMID: 20508892
PDF is available here.
PDF is available here.
Circulation Journal (74)8 2010
Coadministration of carvedilol attenuates nitrate tolerance by preventing cytochrome p450 depletion.
Abstract
Long-term administration of nitroglycerin (NTG) causes tolerance secondary to increased vascular formation of reactive oxygen species. Carvedilol, which has potent antioxidant activity in addition to functioning as an adrenergic blocker, prevents nitrate tolerance by a still to be elucidated mechani...
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PMID: 20574135
PDF is available here.
PDF is available here.
Circulation Journal (74)8 2010
Abstract
Oxidative stress and pulmonary veins (PVs) play critical roles in the pathophysiology of atrial fibrillation. The purpose of the present study was to investigate whether oxidative stress and antioxidant agents can change the electrophysiological characteristics of the left atrium (LA) and PVs.
Conve...
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PMID: 20562495
PDF is available here.
PDF is available here.
Abstract
The existence of different redox pools within the humate was confirmed, with the quinoid-centered redox entities showing the fastest kinetics. The results pertained to all size and polarity fractions....
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PMID: 20354802
PDF is available here.
PDF is available here.
Abstract
These results show that as oxidative radicals induce high proportions of irreversible damages (polymerisation) centrin 2 is highly sensitive to ionising radiation. This could have important consequences on its biological functions....
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PMID: 20586543
PDF is available here.
PDF is available here.
Inflammopharmacology (18)4 2010
Abstract
The methanol extract of Russelia equisetiformis (MRE), which exhibited significant antiinflammatory activity, was evaluated for the possible mode of action by studying its antioxidant potential in adjuvant- induced arthritic rats. 1, 1 diphenyl-2-picrylhydrazyl (DPPH) radical scavenging effect was d...
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PMID: 20119851
PDF is available here.
PDF is available here.
Abstract
We proposed that production of free radicals can be reduced by preventing high blood glucose levels and by the control of instabilities in blood glucose levels. A contributor to these instabilities in blood glucose is glycaemic control by using of fast blood sugar test. Furthermore, the earlier asse...
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PMID: 21850933
PDF is available here.
PDF is available here.
Abstract
Electromagnetic fields (EMFs) played a role in the initiation of living systems, as well as subsequent evolution. The more recent literature on electrochemistry is documented, as well as magnetism. The large numbers of reports on interaction with living systems and the consequences are presented. An...
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PMID: 20509751
PDF is available here.
PDF is available here.
Hawaii medical journal (69)8 2010
Abstract
Cells ability to evade cell death and to proliferate post geno-/cell-toxic stresses, likely leads to formation of cancer. Activation of p38MAPK and p53 following these stresses help protect cells against cancer development by initiating apoptosis. The duration of p38MAPK and p53 activation is regula...
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PMID: 20845286
PDF is available here.
PDF is available here.
Abstract
Vojnosanitetski pregled (67)8 2010
Abstract
Plasma MDA concentration in the group S was significantly higher at 20 min ATR in comparison with the groups T and R (6.78 +/- 0.33 micromolL-1(-1) vs. 4.07 +/- 1.53 and 3.22 +/- 0.9. micromolL-1(-1), respectively). There was a significant difference in MDA concentration in erytrocythes between the...
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PMID: 20845670
PDF is available here.
PDF is available here.
Abstract
The influence of injection periods of 3-(1H-pyrrol-2-yl)-1H-indazole regarding vitamins A, E, C, selenium (Se), malondialdehyde (MDA) levels, and glutathione peroxidase (GSH-Px) activity in rats has been investigated. The substance was given by subcutaneous injection at 20 mg/kg every other day for...
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PMID: 19756400
PDF is available here.
PDF is available here.
Abstract
Betalains are water-soluble pigments with high antiradical capacity which bestow bright colors on flowers and fruits of most plants of the order Caryophyllales. They are classified as betacyanins, exhibiting a violet coloration, and betaxanthins, which exhibit yellow coloration. Trad...
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PMID: 20467875
PDF is available here.
PDF is available here.
Abstract
Betalains are water-soluble pigments with high antiradical capacity which bestow bright colors on flowers and fruits of most plants of the order Caryophyllales. They are classified as betacyanins, exhibiting a violet coloration, and betaxanthins, which exhibit yellow coloration. Trad...
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PMID: 20467875
PDF is available here.
PDF is available here.
Abstract
Betalains are water-soluble pigments with high antiradical capacity which bestow bright colors on flowers and fruits of most plants of the order Caryophyllales. They are classified as betacyanins, exhibiting a violet coloration, and betaxanthins, which exhibit yellow coloration. Trad...
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PMID: 20467875
PDF is available here.
PDF is available here.
Abstract
Betalains are water-soluble pigments with high antiradical capacity which bestow bright colors on flowers and fruits of most plants of the order Caryophyllales. They are classified as betacyanins, exhibiting a violet coloration, and betaxanthins, which exhibit yellow coloration. Trad...
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PMID: 20467875
PDF is available here.
PDF is available here.
Abstract
Betalains are water-soluble pigments with high antiradical capacity which bestow bright colors on flowers and fruits of most plants of the order Caryophyllales. They are classified as betacyanins, exhibiting a violet coloration, and betaxanthins, which exhibit yellow coloration. Trad...
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PMID: 20467875
PDF is available here.
PDF is available here.
Abstract
Betalains are water-soluble pigments with high antiradical capacity which bestow bright colors on flowers and fruits of most plants of the order Caryophyllales. They are classified as betacyanins, exhibiting a violet coloration, and betaxanthins, which exhibit yellow coloration. Trad...
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PMID: 20467875
PDF is available here.
PDF is available here.
Abstract
Betalains are water-soluble pigments with high antiradical capacity which bestow bright colors on flowers and fruits of most plants of the order Caryophyllales. They are classified as betacyanins, exhibiting a violet coloration, and betaxanthins, which exhibit yellow coloration. Trad...
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PMID: 20467875
PDF is available here.
PDF is available here.
Abstract
Betalains are water-soluble pigments with high antiradical capacity which bestow bright colors on flowers and fruits of most plants of the order Caryophyllales. They are classified as betacyanins, exhibiting a violet coloration, and betaxanthins, which exhibit yellow coloration. Trad...
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PMID: 20467875
PDF is available here.
PDF is available here.
Abstract
Betalains are water-soluble pigments with high antiradical capacity which bestow bright colors on flowers and fruits of most plants of the order Caryophyllales. They are classified as betacyanins, exhibiting a violet coloration, and betaxanthins, which exhibit yellow coloration. Trad...
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PMID: 20467875
PDF is available here.
PDF is available here.
Abstract
Betalains are water-soluble pigments with high antiradical capacity which bestow bright colors on flowers and fruits of most plants of the order Caryophyllales. They are classified as betacyanins, exhibiting a violet coloration, and betaxanthins, which exhibit yellow coloration. Trad...
|
PMID: 20467875
PDF is available here.
PDF is available here.
Abstract
Betalains are water-soluble pigments with high antiradical capacity which bestow bright colors on flowers and fruits of most plants of the order Caryophyllales. They are classified as betacyanins, exhibiting a violet coloration, and betaxanthins, which exhibit yellow coloration. Trad...
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PMID: 20467875
PDF is available here.
PDF is available here.
Abstract
Betalains are water-soluble pigments with high antiradical capacity which bestow bright colors on flowers and fruits of most plants of the order Caryophyllales. They are classified as betacyanins, exhibiting a violet coloration, and betaxanthins, which exhibit yellow coloration. Trad...
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PMID: 20467875
PDF is available here.
PDF is available here.
Abstract
Betalains are water-soluble pigments with high antiradical capacity which bestow bright colors on flowers and fruits of most plants of the order Caryophyllales. They are classified as betacyanins, exhibiting a violet coloration, and betaxanthins, which exhibit yellow coloration. Trad...
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PMID: 20467875
PDF is available here.
PDF is available here.
Abstract
Betalains are water-soluble pigments with high antiradical capacity which bestow bright colors on flowers and fruits of most plants of the order Caryophyllales. They are classified as betacyanins, exhibiting a violet coloration, and betaxanthins, which exhibit yellow coloration. Trad...
|
PMID: 20467875
PDF is available here.
PDF is available here.
Abstract
Betalains are water-soluble pigments with high antiradical capacity which bestow bright colors on flowers and fruits of most plants of the order Caryophyllales. They are classified as betacyanins, exhibiting a violet coloration, and betaxanthins, which exhibit yellow coloration. Trad...
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PMID: 20467875
PDF is available here.
PDF is available here.
Heart and Vessels (25)4 2010
Abstract
We sought to determine whether circulating oxidized low-density lipoprotein (ox-LDL) levels differ between subjects with isolated hypercholesterolemia and combined hyperlipidemia, as well as the effect of simvastatin on circulating ox-LDL according to the type of dyslipidemia. Twenty-five subjects w...
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PMID: 20676836
PDF is available here.
PDF is available here.
Abstract
Our data indicate that besides cold and osmotic stress adaptation roles, Csp family proteins also promote efficient host cell invasion and oxidative stress adaptation processes in L. monocytogenes....
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PMID: 20184451
PDF is available here.
PDF is available here.
Biochimica et Biophysica Acta (1804)7 2010
Abstract
We performed a proteomic study to understand how Saccharomyces cerevisiae adapts its metabolism during the exponential growth on three different concentrations of glucose; this information will be necessary to understand yeast carbon metabolism in different environments. We induced a natural diauxic...
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PMID: 20362699
PDF is available here.
PDF is available here.
Abstract
The vast majority of energy necessary for cellular function is produced in mitochondria. Free-radical production and apoptosis are other critical mitochondrial functions. The complex structure, electrochemical properties of the inner mitochondrial membrane (IMM), and genetic control from both mitoch...
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PMID: 20818734
PDF is available here.
PDF is available here.
Minerva Pediatrica (62)3 Suppl 1 2010
Abstract
Our goal is to identify reliable markers for the detection of OS in physiology and pathology. These biomarkers can be useful for several clinical purpose such as to monitor the response to any antioxidant intervention and then develop preventive strategies. The standardization and a large clinical u...
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PMID: 21089735
PDF is available here.
PDF is available here.
Minerva Pediatrica (62)3 Suppl 1 2010
Abstract
We investigated whether oxidative stress can play a role in this process. Here we resume our findings, that recall to a greater safeguard of babies from unjustified pain....
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PMID: 21089720
PDF is available here.
PDF is available here.
Abstract
We observed a statistically increased level of TBARS in plasma and isoprostanes in urine of patients with invasive breast cancer in comparison with a control group. The concentration of tested biomarkers in plasma or urine from patients with invasive breast cancer was also higher than in patients wi...
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PMID: 20577033
PDF is available here.
PDF is available here.
Abstract
We have used a xanthine oxidase/acetaldehyde system to generate tyrosyl radicals on sperm whale myoglobin in the presence of superoxide. Using mass spectrometry we found that superoxide prevented myoglobin dimer formation by repairing the protein tyrosyl radical. An addition product of superoxide at...
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PMID: 20211247
PDF is available here.
PDF is available here.
Abstract
Gas-phase guanine (G) radical cations were generated by electrospraying a solution of guanosine (L) and Cu(NO(3))(2). Collision-induced dissociation (CID) for guanine radical cations yielded five competing dissociation channels, corresponding to the elimination neutral molecules of NH(3), HCN, H(2)N...
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PMID: 20428546
PDF is available here.
PDF is available here.
Abstract
We propose that a different, but also effective, electron-transfer cascade is conserved among the class II photolyases. The existence of such electron transfer pathways is supported by the observation that the catalytically active fully reduced flavin state obtained by photoreduction is maintained e...
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PMID: 20227927
PDF is available here.
PDF is available here.
Abstract
Two low-molecular-weight polysaccharides, GLP(L)1 and GLP(L)2, purified from a crude Ganoderma lucidum polysaccharide preparation GLPP were investigated for their physicochemical properties, structure characterization and antioxidant activities. The results indicated that GLP(L)1 was a glucan with a...
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PMID: 20153767
PDF is available here.
PDF is available here.
Journal of Physical Chemistry B (114)16 2010
Abstract
X-irradiation of L-arginine hydrochloride monohydrate crystals at 66 K led to at least five radicals detectable with K-band Electron Paramagnetic Resonance (EPR), Electron-Nuclear DOuble Resonance (ENDOR) and ENDOR-induced EPR (EIE) techniques. Radicals R1a and R1b were identified as carboxyl-center...
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PMID: 20364864
PDF is available here.
PDF is available here.
Journal of Physical Chemistry B (114)16 2010
Abstract
Triplet-excited riboflavin ((3)RF*) was found by laser flash photolysis to be quenched by polyunsaturated fatty acid methyl esters in tert-butanol/water (7:3, v/v) in a second-order reaction with k approximately 3.0 x 10(5) L mol(-1) s(-1) at 25 degrees C for methyl linoleate and 3.1 x 10(6) L mol(-...
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PMID: 20377218
PDF is available here.
PDF is available here.